ATE196604T1 - Zusammensetzung enthaltend pdgf und dexamethason zur förderung von gewebsreparatur und - regenerierung - Google Patents

Zusammensetzung enthaltend pdgf und dexamethason zur förderung von gewebsreparatur und - regenerierung

Info

Publication number
ATE196604T1
ATE196604T1 AT92908042T AT92908042T ATE196604T1 AT E196604 T1 ATE196604 T1 AT E196604T1 AT 92908042 T AT92908042 T AT 92908042T AT 92908042 T AT92908042 T AT 92908042T AT E196604 T1 ATE196604 T1 AT E196604T1
Authority
AT
Austria
Prior art keywords
regeneration
dexamethason
composition containing
tissue repair
pdgf
Prior art date
Application number
AT92908042T
Other languages
English (en)
Inventor
Robert Bruce Rutherford
Marc F Charette
Original Assignee
Creative Biomolecules Inc
Univ Connecticut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Creative Biomolecules Inc, Univ Connecticut filed Critical Creative Biomolecules Inc
Application granted granted Critical
Publication of ATE196604T1 publication Critical patent/ATE196604T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT92908042T 1991-03-12 1992-03-12 Zusammensetzung enthaltend pdgf und dexamethason zur förderung von gewebsreparatur und - regenerierung ATE196604T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/669,070 US5149691A (en) 1991-03-12 1991-03-12 Issue repair and regeneration through the use of platelet derived growth factor (pdgf) in combination with dexamethasone
PCT/US1992/002043 WO1992016181A2 (en) 1991-03-12 1992-03-12 Composition for promoting tissue repair and regeneration

Publications (1)

Publication Number Publication Date
ATE196604T1 true ATE196604T1 (de) 2000-10-15

Family

ID=24684879

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92908042T ATE196604T1 (de) 1991-03-12 1992-03-12 Zusammensetzung enthaltend pdgf und dexamethason zur förderung von gewebsreparatur und - regenerierung

Country Status (8)

Country Link
US (2) US5149691A (de)
EP (1) EP0575484B1 (de)
JP (1) JPH07505858A (de)
AT (1) ATE196604T1 (de)
AU (1) AU656372B2 (de)
CA (1) CA2106073C (de)
DE (1) DE69231486T2 (de)
WO (1) WO1992016181A2 (de)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5149691A (en) * 1991-03-12 1992-09-22 Creative Biomolecules, Inc. Issue repair and regeneration through the use of platelet derived growth factor (pdgf) in combination with dexamethasone
US5770209A (en) * 1991-08-30 1998-06-23 University Of South Florida Acceleration of wound healing using connective tissue growth factor
US7384634B2 (en) * 1991-08-30 2008-06-10 University Of South Florida Connective tissue growth factor
US5837258A (en) * 1991-08-30 1998-11-17 University Of South Florida Induction of tissue, bone or cartilage formation using connective tissue growth factor
US5408040A (en) * 1991-08-30 1995-04-18 University Of South Florida Connective tissue growth factor(CTGF)
US5326695A (en) * 1992-05-15 1994-07-05 Ludwig Institute For Cancer Research Platelet derived growth factor agonists
US5444151A (en) * 1992-05-15 1995-08-22 Ludwig Institute For Cancer Research Platelet derived growth factor antagonists
DE4228457A1 (de) * 1992-08-27 1994-04-28 Beiersdorf Ag Herstellung von heterodimerem PDGF-AB mit Hilfe eines bicistronischen Vektorsystems in Säugerzellen
JP3699111B2 (ja) * 1993-03-29 2005-09-28 ザイモジェネティクス，インコーポレイティド Ｐｄｇｆおよびビタミンｄを含有する骨芽細胞の成長を刺激する組成物
US5455041A (en) * 1993-09-13 1995-10-03 Research Foundation Of State University Of New York At Buffalo Method for inducing periodontal tissue regeneration
US5942496A (en) * 1994-02-18 1999-08-24 The Regent Of The University Of Michigan Methods and compositions for multiple gene transfer into bone cells
US6551618B2 (en) 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
EP0743066A3 (de) * 1995-05-16 1998-09-30 Mitsui Pharmaceuticals, Inc. Wundheilmittel
US6902584B2 (en) 1995-10-16 2005-06-07 Depuy Spine, Inc. Bone grafting matrix
US5776193A (en) * 1995-10-16 1998-07-07 Orquest, Inc. Bone grafting matrix
AU3214797A (en) * 1996-05-28 1998-01-05 Regents Of The University Of Michigan, The Engineering oral tissues
DE19754140A1 (de) * 1997-12-05 1999-06-24 Era Beschichtung Gmbh & Co Kg Innenraummaterial auf der Basis von Kunststoff, Verfahren zu dessen Herstellung und Verwendung desselben
MXPA00000009A (es) 1998-06-22 2005-09-08 Autologous Wound Therapy Inc Solicitud para patente de utilidad para curativo de heridas mejorado enriquecido con plaquetas.
WO2001032197A2 (en) * 1999-11-02 2001-05-10 Eli Lilly And Company Methods of using lp8, a pdgf-related protein, to treat musculoskeletal disorders
US7847087B2 (en) 2001-03-05 2010-12-07 Siemens Healthcare Diagnostics Inc. Methods and primers for evaluating HIV-1 mutations
RU2004137651A (ru) * 2001-06-07 2005-10-10 Чю Консалтинг Инк. (US) Составы и способы профилактики и лечения афтозных язв и поражений вирусом герпес симплекс
US7819888B2 (en) * 2001-10-23 2010-10-26 Innovasive Devices, Inc. Method and apparatus for harvesting and implanting bone plugs
DE10152956A1 (de) * 2001-10-26 2003-05-15 Fresenius Kabi De Gmbh Pharmazeutische Zusammensetzung, einen Wachstumsfaktor und/oder ein Zytokin und ein antiseptisches Biguanid umfassend
RU2308954C2 (ru) * 2002-05-09 2007-10-27 Медиджинез Фармацевтическая композиция для лечения ран, содержащая плазму или сыворотку крови
US6616923B1 (en) * 2002-07-26 2003-09-09 Chiou Consulting, Inc. Aqueous compositions for facial cosmetics
US20040018220A1 (en) * 2002-07-26 2004-01-29 Chiou Consulting, Inc. Aqueous compositions for facial cosmetics
US20060076295A1 (en) 2004-03-15 2006-04-13 The Trustees Of Columbia University In The City Of New York Systems and methods of blood-based therapies having a microfluidic membraneless exchange device
US20040225249A1 (en) 2003-03-14 2004-11-11 Leonard Edward F. Systems and methods of blood-based therapies having a microfluidic membraneless exchange device
US7309232B2 (en) * 2003-10-10 2007-12-18 Dentigenix Inc. Methods for treating dental conditions using tissue scaffolds
US7258875B2 (en) * 2003-12-04 2007-08-21 Chiou Consulting, Inc. Compositions and methods for topical treatment of skin infection
US8293890B2 (en) * 2004-04-30 2012-10-23 Advanced Cardiovascular Systems, Inc. Hyaluronic acid based copolymers
GB0414803D0 (en) * 2004-07-01 2004-08-04 Glaxo Group Ltd Composition
US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
US20060115266A1 (en) * 2004-12-01 2006-06-01 Gil Levi All-optical protection signaling systems and methods in optical communication networks
US8119591B2 (en) * 2005-08-01 2012-02-21 Genera Istrazivanja D.O.O. Methods and compositions for regenerating articular cartilage
KR20080084808A (ko) 2005-11-17 2008-09-19 바이오미메틱 세라퓨틱스, 인크. ｒｈＰＤＧＦ-ＢＢ 및 생체적합성 매트릭스를 사용하는상악안면골 보강
AU2006335748A1 (en) 2006-01-23 2007-07-26 Imagene Co., Ltd. Novel peptide and use thereof
ES2427993T3 (es) * 2006-02-09 2013-11-05 Biomimetic Therapeutics, Llc Composiciones y métodos para el tratamiento de hueso
EP2019658B1 (de) 2006-05-22 2012-01-25 The Trustees of Columbia University in the City of New York Verfahren für membranlosen mikrofluidaustausch in einem h-filter und filterung der extraktionsflüssigkeitsausgangsströme
US9642891B2 (en) 2006-06-30 2017-05-09 Biomimetic Therapeutics, Llc Compositions and methods for treating rotator cuff injuries
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
WO2008073628A2 (en) * 2006-11-03 2008-06-19 Biomimetic Therapeutics, Inc. Compositions and methods for arthrodetic procedures
AU2013203287B2 (en) * 2006-11-03 2015-12-17 Stryker Corporation Compositions and methods for arthrodetic procedures
US9511076B2 (en) * 2008-05-30 2016-12-06 Clarion Research Group Formulations and methods for recovery from dental surgery
WO2009052221A2 (en) * 2007-10-15 2009-04-23 The Regents Of The University Of Colorado Methods for extracting platelets and compositions obtained therefrom
MX2010007442A (es) 2008-01-07 2010-12-21 Vereniging Voor Christelijk Hoger Onderwijs Wetenschappelijk Onderzoek En Patientenzorg Uso de peptidos para promover la curacion de heridas.
BRPI0907473A2 (pt) 2008-02-04 2019-09-24 Univ Columbia métodos, sistemas e dispositivos de separação de fluidos
AU2009212151C1 (en) 2008-02-07 2015-09-17 Stryker Corporation Compositions and methods for distraction osteogenesis
MX2011002555A (es) 2008-09-09 2011-08-03 Biomimetic Therapeutics Inc Composiciones de factor de crecimiento derivadas de plaquetas y metodo para el tratamiento de lesiones de tendon y ligamentos.
US20120100111A1 (en) * 2009-03-06 2012-04-26 Universite Paris Descartes Method for treating cancer
WO2011103598A1 (en) 2010-02-22 2011-08-25 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods for the treatment of tendinopathies
ES2410804T3 (es) 2010-06-14 2013-07-03 Gene Signal International Sa Péptidos para la curación de heridas
US8288334B2 (en) 2010-06-14 2012-10-16 Gene Signal International Sa Peptides for wound healing
US20130157949A1 (en) 2010-06-14 2013-06-20 Gene Signal International Sa Novel Peptides for Wound Healing
WO2012021249A2 (en) 2010-07-12 2012-02-16 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-trna synthetases
US20130108683A1 (en) * 2011-10-25 2013-05-02 Biomimetic Therapeutics, Inc. Compositions and methods for treating partial and full thickness wounds and injuries
AU2013221317B2 (en) 2012-02-16 2017-07-06 Pangu Biopharma Limited Histidyl-tRNA synthetases for treating autoimmune and inflammatory diseases
ES2847383T3 (es) 2013-03-15 2021-08-03 Atyr Pharma Inc Conjugados de Fc-histidil-ARNt sintetasa
CA2962954A1 (en) 2014-10-14 2016-04-21 Samuel Lynch Compositions for treating wounds
ES2994451T3 (en) 2017-04-20 2025-01-24 Atyr Pharma Inc Compositions for treating lung inflammation
KR102668789B1 (ko) 2018-11-23 2024-05-24 (주)메디코스바이오텍 창상치료용 약학조성물
CZ308845B6 (cs) 2019-01-21 2021-07-07 Globetech Innovation S.R.O Farmaceutická směs topicky hojivých peptidových složek pro použití k topické léčbě kožních defektů a/nebo k topickému hojení ran
PL245202B1 (pl) 2020-03-06 2024-06-03 Gdanski Univ Medyczny Lipopeptydowe koniugaty i ich sole, sposób wytwarzania lipopeptydowych koniugatów i ich soli, kompozycja farmaceutyczna zawierająca lipopeptydowy koniugat i jego sole do leczenia ran przewlekłych
LU505892B1 (fr) 2023-12-21 2025-06-24 Lumatrix Formule pharmaceutique de cicatrisation et de régénération de la peau et son utilisation

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6028999A (ja) * 1983-06-30 1985-02-14 Maruho Kk 細胞増殖促進作用を有するたんぱく質、その組成物と製造方法
US4957742A (en) * 1984-11-29 1990-09-18 Regents Of The University Of Minnesota Method for promoting hair growth
US5124316A (en) * 1986-11-14 1992-06-23 President And Fellows Of Harvard College Method for periodontal regeneration
US4861757A (en) * 1986-11-14 1989-08-29 Institute Of Molecular Biology Wound healing and bone regeneration using PDGF and IGF-I
WO1988004180A1 (en) * 1986-12-11 1988-06-16 National Research Development Corporation Improvements in or relating to the use of epidermal growth factor
US4808402A (en) * 1987-05-29 1989-02-28 Northwestern University Method and compositions for modulating neovascularization
US4874746A (en) * 1987-12-22 1989-10-17 Institute Of Molecular Biology, Inc. Wound headling composition of TGF-alpha and PDGF
AU657472B2 (en) * 1990-03-06 1995-03-16 Claude Paul Genero Towel or blanket support device
US5149691A (en) * 1991-03-12 1992-09-22 Creative Biomolecules, Inc. Issue repair and regeneration through the use of platelet derived growth factor (pdgf) in combination with dexamethasone
WO1992018153A1 (en) * 1991-04-12 1992-10-29 Creative Biomolecules, Inc. Method of treating gastrointestinal ulcers with platelet derived growth factor

Also Published As

Publication number Publication date
US5376636A (en) 1994-12-27
DE69231486D1 (de) 2000-11-02
AU1559192A (en) 1992-10-21
WO1992016181A3 (en) 1992-11-12
DE69231486T2 (de) 2001-04-26
EP0575484B1 (de) 2000-09-27
EP0575484A1 (de) 1993-12-29
CA2106073C (en) 2003-09-30
WO1992016181A2 (en) 1992-10-01
AU656372B2 (en) 1995-02-02
US5149691A (en) 1992-09-22
CA2106073A1 (en) 1993-09-13
JPH07505858A (ja) 1995-06-29

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