ATE196735T1 - Neue antibiotika und ihre enthaltende antibiotische zusammensetzungen für die inhibition gram positiven bakterien und mykoplasmen. - Google Patents

Neue antibiotika und ihre enthaltende antibiotische zusammensetzungen für die inhibition gram positiven bakterien und mykoplasmen.

Info

Publication number
ATE196735T1
ATE196735T1 AT95930997T AT95930997T ATE196735T1 AT E196735 T1 ATE196735 T1 AT E196735T1 AT 95930997 T AT95930997 T AT 95930997T AT 95930997 T AT95930997 T AT 95930997T AT E196735 T1 ATE196735 T1 AT E196735T1
Authority
AT
Austria
Prior art keywords
positive bacteria
inhibition
mycoplasms
compositions containing
gram positive
Prior art date
Application number
AT95930997T
Other languages
English (en)
Inventor
Neal C Brown
George Wright
Original Assignee
Univ Massachusetts Medical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Massachusetts Medical filed Critical Univ Massachusetts Medical
Application granted granted Critical
Publication of ATE196735T1 publication Critical patent/ATE196735T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
AT95930997T 1994-08-30 1995-08-30 Neue antibiotika und ihre enthaltende antibiotische zusammensetzungen für die inhibition gram positiven bakterien und mykoplasmen. ATE196735T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/298,011 US5516905A (en) 1994-08-30 1994-08-30 Antibiotic compounds and methods to treat gram-positive bacterial and mycoplasmal infections
PCT/US1995/010943 WO1996006614A1 (en) 1994-08-30 1995-08-30 Novel antibiotic compounds and methods to treat gram-positive bacterial and mycoplasmal infections

Publications (1)

Publication Number Publication Date
ATE196735T1 true ATE196735T1 (de) 2000-10-15

Family

ID=23148623

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95930997T ATE196735T1 (de) 1994-08-30 1995-08-30 Neue antibiotika und ihre enthaltende antibiotische zusammensetzungen für die inhibition gram positiven bakterien und mykoplasmen.

Country Status (10)

Country Link
US (1) US5516905A (de)
EP (1) EP0772439B1 (de)
JP (1) JPH10509134A (de)
KR (1) KR970705392A (de)
AT (1) ATE196735T1 (de)
AU (1) AU703511B2 (de)
CA (1) CA2198739A1 (de)
DE (1) DE69519031T2 (de)
ES (1) ES2151608T3 (de)
WO (1) WO1996006614A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5994361A (en) * 1994-06-22 1999-11-30 Biochem Pharma Substituted purinyl derivatives with immunomodulating activity
FR2751224B1 (fr) * 1996-07-19 1998-11-20 Rhone Merieux Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs
US7432365B1 (en) 1998-01-27 2008-10-07 O'donnell Michael E DNA molecules encoding beta clamp proteins of gram positive bacteria
WO1999037661A1 (en) 1998-01-27 1999-07-29 The Rockefeller University Dna replication proteins of gram positive bacteria and their use to screen for chemical inhibitors
US6417180B1 (en) * 1998-10-07 2002-07-09 University Of Massachusetts Zinc finger-reactive antimicrobial compounds
WO2000037471A1 (en) * 1998-12-23 2000-06-29 Neurogen Corporation 2-amino-9-alkylpurines: gaba brain receptor ligands
US6448256B1 (en) 1999-05-24 2002-09-10 University Of Massachusetts Antibiotic prodrugs
AU6749900A (en) * 1999-07-29 2001-02-19 Rockefeller University, The Dna replication proteins of gram positive bacteria and their use to screen for chemical inhibitors
AU2247701A (en) * 1999-10-21 2001-04-30 Merck & Co., Inc. Gram-positive selective antibacterial compounds, compositions containing such compounds and methods of treatment
US6777420B2 (en) * 2001-06-15 2004-08-17 Microbiotix, Inc. Heterocyclic antibacterial compounds
WO2003011297A1 (en) * 2001-06-15 2003-02-13 University Of Massachusetts N3-substituted 6-anilinopyrimidines and methods to treat gram-positive bacterial and mycoplasmal infections
WO2003000665A1 (de) * 2001-06-22 2003-01-03 Bayer Aktiengesellschaft Antibakterielle uracilderivate.
WO2003000664A1 (de) * 2001-06-22 2003-01-03 Bayer Aktiengesellschaft Uracilderivative und ihre verwendung bei der behandlung bakterieller erkrankungen
US6926763B2 (en) * 2002-02-08 2005-08-09 Glsynthesis, Inc. Purine and isosteric antibacterial compounds
DE10208256A1 (de) * 2002-02-26 2003-09-04 Bayer Ag Piperidinouracile
US7482355B2 (en) * 2002-08-24 2009-01-27 Astrazeneca Ab Pyrimidine derivatives as modulators of chemokine receptor activity
KR20050084027A (ko) * 2002-11-28 2005-08-26 쉐링 악티엔게젤샤프트 Ｃｈｋ-, ｐｄｋ- 및 ａｋｔ-억제성 피리미딘, 그의제조방법 및 약제로서의 그의 용도
AU2003287290A1 (en) * 2003-09-11 2005-04-27 Smithsonian Tropical Research Institute Fluorescense based bioassay for anti-parasitic drugs
WO2009034386A1 (en) * 2007-09-13 2009-03-19 Astrazeneca Ab Derivatives of adenine and 8-aza-adenine and uses thereof-796
CA2772907C (en) 2009-09-11 2018-01-09 Glsynthesis Inc. Selective antibacterials for clostridium difficile infections
SMT202000071T1 (it) 2013-06-21 2020-03-13 Myokardia Inc Composti di pirimidinadione contro le condizioni cardiache
WO2014205234A1 (en) 2013-06-21 2014-12-24 MyoKardia, Inc. Cycloalkyl-substituted pyrimidinedione compounds

Also Published As

Publication number Publication date
DE69519031T2 (de) 2001-05-17
EP0772439A1 (de) 1997-05-14
WO1996006614A1 (en) 1996-03-07
KR970705392A (ko) 1997-10-09
AU703511B2 (en) 1999-03-25
JPH10509134A (ja) 1998-09-08
US5516905A (en) 1996-05-14
ES2151608T3 (es) 2001-01-01
EP0772439B1 (de) 2000-10-04
EP0772439A4 (de) 1998-01-07
CA2198739A1 (en) 1996-03-07
AU3418595A (en) 1996-03-22
DE69519031D1 (de) 2000-11-09

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties