ATE197126T1 - Verbindungen und methoden zur sublingualen oder buccalen verabreichung von therapeutischen agentien - Google Patents

Verbindungen und methoden zur sublingualen oder buccalen verabreichung von therapeutischen agentien

Info

Publication number
ATE197126T1
ATE197126T1 AT92918805T AT92918805T ATE197126T1 AT E197126 T1 ATE197126 T1 AT E197126T1 AT 92918805 T AT92918805 T AT 92918805T AT 92918805 T AT92918805 T AT 92918805T AT E197126 T1 ATE197126 T1 AT E197126T1
Authority
AT
Austria
Prior art keywords
sublingual
therapeutic agents
buccal administration
compounds
methods
Prior art date
Application number
AT92918805T
Other languages
English (en)
Inventor
Lu Mou-Ying Fu
Thomas L Reiland
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE197126T1 publication Critical patent/ATE197126T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT92918805T 1991-08-26 1992-08-18 Verbindungen und methoden zur sublingualen oder buccalen verabreichung von therapeutischen agentien ATE197126T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75084391A 1991-08-26 1991-08-26
PCT/US1992/006944 WO1993003751A1 (en) 1991-08-26 1992-08-18 Compositions and methods for the sublingual or buccal administration of therapeutic agents

Publications (1)

Publication Number Publication Date
ATE197126T1 true ATE197126T1 (de) 2000-11-15

Family

ID=25019382

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92918805T ATE197126T1 (de) 1991-08-26 1992-08-18 Verbindungen und methoden zur sublingualen oder buccalen verabreichung von therapeutischen agentien

Country Status (14)

Country Link
US (1) US5284657A (de)
EP (1) EP0601053B1 (de)
JP (1) JPH06510046A (de)
KR (1) KR100256715B1 (de)
AT (1) ATE197126T1 (de)
AU (1) AU669856B2 (de)
CA (1) CA2103163C (de)
DE (1) DE69231536T2 (de)
DK (1) DK0601053T3 (de)
ES (1) ES2153362T3 (de)
GR (1) GR3035116T3 (de)
IL (1) IL102857A (de)
PT (1) PT100812B (de)
WO (1) WO1993003751A1 (de)

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US5716928A (en) * 1995-06-07 1998-02-10 Avmax, Inc. Use of essential oils to increase bioavailability of oral pharmaceutical compounds
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EP0880969A1 (de) * 1997-05-28 1998-12-02 Applied Research Systems ARS Holdings N.V. Im physiologischem Medium schwerlösliche pharmazeutische Peptidezusammensetzungen
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AU4894697A (en) 1997-10-01 1999-04-23 Flemington Pharmaceutical Corporation Buccal, polar and non-polar spray or capsule
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US20040136914A1 (en) * 1997-10-01 2004-07-15 Dugger Harry A. Buccal, polar and non-polar spray containing ondansetron
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US6426090B1 (en) * 1999-04-06 2002-07-30 Wm. Wrigley Jr. Company Over-coated product including tableted center and medicament
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US6645535B2 (en) 1999-09-02 2003-11-11 Wm. Wrigley Jr. Company Method of making coated chewing gum products containing various antacids
US6569472B1 (en) 2000-09-01 2003-05-27 Wm. Wrigley Jr. Company Coated chewing gum products containing antacid and method of making
US6663849B1 (en) 2000-09-01 2003-12-16 Wm. Wrigley Jr. Company Antacid chewing gum products coated with high viscosity materials
US6541048B2 (en) 1999-09-02 2003-04-01 Wm. Wrigley Jr. Company Coated chewing gum products containing an acid blocker and process of preparing
US9253991B2 (en) 1999-09-20 2016-02-09 Jack Barreca Chewing gum with B vitamins
AU3885201A (en) * 1999-09-20 2001-04-24 Mastercare Diet and weight control gum and sucker
US9387168B2 (en) 1999-09-20 2016-07-12 Jack Barreca Chewing gum with tomatidine
US6572900B1 (en) 2000-06-09 2003-06-03 Wm. Wrigley, Jr. Company Method for making coated chewing gum products including a high-intensity sweetener
US7115288B2 (en) * 2000-06-09 2006-10-03 Wm. Wrigley Jr. Company Method for making coated chewing gum products with a coating including an aldehyde flavor and a dipeptide sweetener
US6444241B1 (en) 2000-08-30 2002-09-03 Wm. Wrigley Jr. Company Caffeine coated chewing gum product and process of making
US6579545B2 (en) 2000-12-22 2003-06-17 Wm. Wrigley Jr. Company Coated chewing gum products containing an antigas agent
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Also Published As

Publication number Publication date
AU669856B2 (en) 1996-06-27
IL102857A (en) 1997-02-18
WO1993003751A1 (en) 1993-03-04
CA2103163C (en) 1998-10-20
IL102857A0 (en) 1993-01-31
EP0601053A4 (en) 1996-07-17
ES2153362T3 (es) 2001-03-01
DE69231536T2 (de) 2001-06-13
AU2519392A (en) 1993-03-16
EP0601053B1 (de) 2000-10-25
US5284657A (en) 1994-02-08
JPH06510046A (ja) 1994-11-10
KR100256715B1 (ko) 2000-05-15
CA2103163A1 (en) 1993-03-04
PT100812A (pt) 1993-09-30
PT100812B (pt) 1999-07-30
DK0601053T3 (da) 2001-01-08
GR3035116T3 (en) 2001-03-30
EP0601053A1 (de) 1994-06-15
DE69231536D1 (de) 2000-11-30

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Legal Events

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REN Ceased due to non-payment of the annual fee