ATE199157T1 - Multichromophore fluoreszierende sonden - Google Patents

Multichromophore fluoreszierende sonden

Info

Publication number
ATE199157T1
ATE199157T1 AT91906708T AT91906708T ATE199157T1 AT E199157 T1 ATE199157 T1 AT E199157T1 AT 91906708 T AT91906708 T AT 91906708T AT 91906708 T AT91906708 T AT 91906708T AT E199157 T1 ATE199157 T1 AT E199157T1
Authority
AT
Austria
Prior art keywords
labels
fluorescent
fluorescent probe
dyes
labeling
Prior art date
Application number
AT91906708T
Other languages
English (en)
Inventor
Alexander Maniot Glazer
Richard Alfred Mathies
Konan Peck
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of ATE199157T1 publication Critical patent/ATE199157T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44717Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G01N27/44726Arrangements for investigating the separated zones, e.g. localising zones by optical means using specific dyes, markers or binding molecules
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Electrochemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Harvester Elements (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT91906708T 1990-03-14 1991-03-08 Multichromophore fluoreszierende sonden ATE199157T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49330790A 1990-03-14 1990-03-14
PCT/US1991/001604 WO1991013897A1 (en) 1990-03-14 1991-03-08 Multichromophore fluorescent probes

Publications (1)

Publication Number Publication Date
ATE199157T1 true ATE199157T1 (de) 2001-02-15

Family

ID=23959690

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91906708T ATE199157T1 (de) 1990-03-14 1991-03-08 Multichromophore fluoreszierende sonden

Country Status (7)

Country Link
EP (1) EP0520014B1 (de)
JP (1) JPH05505526A (de)
AT (1) ATE199157T1 (de)
AU (1) AU7579891A (de)
CA (1) CA2078006C (de)
DE (1) DE69132535T2 (de)
WO (1) WO1991013897A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9218131D0 (en) * 1992-08-26 1992-10-14 Slater James H A method of marking a liquid
JP3260884B2 (ja) 1993-02-05 2002-02-25 キヤノン株式会社 標識複合体、それを用いる分析法、生体関連物質の検出および定量の方法
US5808077A (en) * 1993-06-30 1998-09-15 Abbott Laboratories Intercalators having affinity for DNA and methods of use
EP0684316B1 (de) * 1994-04-29 2004-10-20 Johnson & Johnson Clinical Diagnostics, Inc. Homogenes Verfahren zum Nachweis von Doppelstrang-Nukleinsäuren mittels fluoreszierender Farbstoffe und dafür nützliche Kits
US5571673A (en) * 1994-11-23 1996-11-05 Hoffmann-La Roche Inc. Methods for in-solution quenching of fluorescently labeled oligonucleotide probes
US6037130A (en) * 1998-07-28 2000-03-14 The Public Health Institute Of The City Of New York, Inc. Wavelength-shifting probes and primers and their use in assays and kits
GB0103611D0 (en) * 2001-02-14 2001-03-28 Zetatronics Ltd Further improved method for detecting cells

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4737454A (en) * 1983-07-14 1988-04-12 Molecular Diagnostics, Inc. Fast photochemical method of labelling nucleic acids for detection purposes in hybridization assays
US4743535A (en) * 1984-11-07 1988-05-10 Miles Inc. Hybridization assay employing labeled probe and anti-hybrid
US4748111A (en) * 1984-03-12 1988-05-31 Molecular Diagnostics, Inc. Nucleic acid-protein conjugate used in immunoassay

Also Published As

Publication number Publication date
EP0520014B1 (de) 2001-02-14
AU7579891A (en) 1991-10-10
EP0520014A4 (de) 1994-04-27
EP0520014A1 (de) 1992-12-30
DE69132535D1 (de) 2001-03-22
CA2078006C (en) 2002-02-05
JPH05505526A (ja) 1993-08-19
WO1991013897A1 (en) 1991-09-19
CA2078006A1 (en) 1991-09-15
DE69132535T2 (de) 2001-06-07

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Legal Events

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