ATE199730T1 - Oberflächenaktives lungenprotein und verwandte polypeptide - Google Patents

Oberflächenaktives lungenprotein und verwandte polypeptide

Info

Publication number
ATE199730T1
ATE199730T1 AT93119102T AT93119102T ATE199730T1 AT E199730 T1 ATE199730 T1 AT E199730T1 AT 93119102 T AT93119102 T AT 93119102T AT 93119102 T AT93119102 T AT 93119102T AT E199730 T1 ATE199730 T1 AT E199730T1
Authority
AT
Austria
Prior art keywords
amino acid
acid residue
related polypeptides
lung protein
polypeptides
Prior art date
Application number
AT93119102T
Other languages
English (en)
Inventor
Charles G Cochrane
Susan D Revak
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Application granted granted Critical
Publication of ATE199730T1 publication Critical patent/ATE199730T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Materials For Medical Uses (AREA)
AT93119102T 1988-01-06 1989-01-05 Oberflächenaktives lungenprotein und verwandte polypeptide ATE199730T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14120088A 1988-01-06 1988-01-06
US07/293,201 US5164369A (en) 1988-01-06 1989-01-04 Pulmonary surfactant protein and related polypeptide

Publications (1)

Publication Number Publication Date
ATE199730T1 true ATE199730T1 (de) 2001-03-15

Family

ID=26838883

Family Applications (2)

Application Number Title Priority Date Filing Date
AT93119102T ATE199730T1 (de) 1988-01-06 1989-01-05 Oberflächenaktives lungenprotein und verwandte polypeptide
AT89901885T ATE196298T1 (de) 1988-01-06 1989-01-05 Oberflächenaktives lungenprotein und verwandte polypeptide

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT89901885T ATE196298T1 (de) 1988-01-06 1989-01-05 Oberflächenaktives lungenprotein und verwandte polypeptide

Country Status (8)

Country Link
US (1) US5164369A (de)
EP (2) EP0593094B1 (de)
JP (2) JP3009690B2 (de)
AT (2) ATE199730T1 (de)
DE (2) DE68929287T2 (de)
DK (1) DK174818B1 (de)
FI (1) FI102180B1 (de)
WO (1) WO1989006657A1 (de)

Families Citing this family (51)

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AU2609488A (en) * 1987-11-07 1989-06-01 Agricultural And Food Research Council, The Emulsifiers
US5260273A (en) * 1988-01-06 1993-11-09 The Scripps Research Institute Pulmonary surfactant protein and related polypeptide
US6613734B2 (en) * 1988-01-06 2003-09-02 The Scripps Research Institute Peptides-containing liposomal surfactants
US6013619A (en) * 1988-01-06 2000-01-11 The Scripps Research Institute Pulmonary surfactants and therapeutic uses, including pulmonary lavage
US5238920A (en) * 1989-08-22 1993-08-24 Abbott Laboratories Pulmonary surfactant protein fragments
US5272252A (en) * 1991-11-04 1993-12-21 Merrell Dow Pharmaceuticals Inc. Synthetic lung surfactant having antioxidant properties
EP0635028B1 (de) * 1992-04-10 2003-01-22 Abbott Laboratories Fragmente eines oberflächenaktiven lungenproteins
US6129934A (en) * 1995-06-07 2000-10-10 Ony, Inc. Modification of animal lung surfactant for treating respiratory disease due to lung surfactant deficiency or dysfunction
DE69620801T2 (de) * 1995-11-20 2002-10-10 Ortho Mcneil Pharm Inc Verfahren zur solubisierung des pulmonnären oberflächeraktiven peptides
CZ292186B6 (cs) 1996-01-24 2003-08-13 Altana Pharma Ag Způsob výroby práškového prostředku s obsahem plicní povrchově aktivní látky, práškový prostředek a jeho použití
US6031075A (en) * 1996-02-05 2000-02-29 Children's Hospital Medical Center Mature alveolar SP-B and a process for producing the same
WO1997035882A1 (en) * 1996-03-27 1997-10-02 Ortho Pharmaceutical Corporation Lyophilized pulmonary surfactant peptide compositions
US6013764A (en) 1996-07-17 2000-01-11 Ortho Pharmaceutical Corp. Liquid phase peptide synthesis of KL-4 pulmonary surfactant
WO2003033014A2 (de) 2001-10-11 2003-04-24 Altana Pharma Ag Neue verwendung von lungensurfactant
KR20110017465A (ko) * 2002-04-25 2011-02-21 더 스크립스 리서치 인스티튜트 폐질환 증상의 치료 및 예방
AU2004296206A1 (en) * 2003-12-04 2005-06-23 The Scripps Research Institute Treatment and preventions of asthma
US20060078506A1 (en) * 2004-05-20 2006-04-13 Ralph Niven Methods, systems and devices for noninvasive pulmonary delivery
EP1781323B1 (de) 2004-08-06 2010-02-17 Nycomed GmbH Zusammensetzung aus einem pulmonalen surfactant und einem von tnf stammenden peptid
US7464012B2 (en) * 2004-12-10 2008-12-09 L'air Liquide, Societe Anonyme A Directoire Et Conseil De Surveillance Pour L'etude Et L'exploitation Des Procedes Georges Claude Simplified process simulator
US7582312B2 (en) 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
US8337815B2 (en) * 2004-12-23 2012-12-25 Discovery Laboratories, Inc. Pulmonary surfactant formulations
WO2006074296A1 (en) 2005-01-06 2006-07-13 Discovery Laboratories, Inc. Surfactant treatment regimen for treating or preventing bronchopulmonary dysplasia
US8028697B2 (en) 2005-04-28 2011-10-04 Trudell Medical International Ventilator circuit and method for the use thereof
KR101486183B1 (ko) 2006-02-08 2015-01-28 모르포테크, 인크. 항원성 ｇｍ-ｃｓｆ 펩티드 및 ｇｍ-ｃｓｆ에 대한 항체
WO2008036293A1 (en) * 2006-09-19 2008-03-27 Discovery Laboratories, Inc. Pulmonary surfactant formulations and methods for promoting mucus clearance
US7951781B2 (en) 2006-11-02 2011-05-31 University Of Iowa Research Foundation Methods and compositions related to PLUNC surfactant polypeptides
CN101754747A (zh) * 2007-06-05 2010-06-23 Paka肺部医药公司 用于向肺脏递送药物的方法以及组合物
US8048043B2 (en) 2007-06-08 2011-11-01 Chiesi Farmaceutici S. P. A. Method of administration of a pulmonary surfactant
HRP20160258T1 (hr) 2008-03-17 2016-04-22 Discovery Laboratories, Inc. Adapter za cijevni sustav ventilacije i proksimalni sustav za dovođenje aerosola
ES2402241T3 (es) 2008-10-22 2013-04-30 Trudell Medical International Sistema de suministro de aerosol modular
US9289388B2 (en) 2008-12-10 2016-03-22 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of medicaments to the lungs
BR112012004651B1 (pt) 2009-09-08 2022-02-08 Chiesi Farmaceutici S.P.A. Surfactante pulmonar exógeno, uso de uma combinação terapêutica, medicamento e kit
WO2011035140A1 (en) 2009-09-18 2011-03-24 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of contrast moieties to the lungs
WO2013188016A2 (en) 2012-05-04 2013-12-19 Discovery Laboratories, Inc. Surfactant therapy for exposure to ionizing radiation
EP3106090A1 (de) 2015-06-15 2016-12-21 CHIESI FARMACEUTICI S.p.A. System zur effektiven und atemsynchronisierten abgabe eines medikaments in die lungen
EP3285645B1 (de) 2015-04-22 2020-08-12 Chiesi Farmaceutici S.p.A. System zur effektiven und atemsynchronisierten abgabe eines medikaments in die lungen
WO2016173634A1 (en) 2015-04-28 2016-11-03 Chiesi Farmaceutici S.P.A Device for facilitating the administration of a medicament to the lung by a catheter
JP2018514545A (ja) 2015-04-30 2018-06-07 ユニバーシティ オブ ブレーメン 医療用および美容用の新規な皮膚ケア製造物
CN109496159A (zh) 2016-07-28 2019-03-19 奇斯药制品公司 用于递送雾化药剂的方法和系统
AU2017349790A1 (en) 2016-10-26 2019-05-02 Chiesi Farmaceutici S.P.A. Device for facilitating the administration of a medicament to the lung by a catheter
JP7777392B2 (ja) 2016-12-22 2025-11-28 キエージ・フアルマチエウテイチ・エツセ・ピ・ア 進行性のｂｐｄの処置のための肺サーファクタント及びステロイドを含む処置的組み合わせ物
TW201927286A (zh) 2017-12-15 2019-07-16 義大利商凱西製藥公司 用於噴霧投藥之包含肺表面張力素的藥學調配物
WO2019115771A1 (en) 2017-12-15 2019-06-20 Pari Pharma Gmbh Nebuliser system, holding system, combination comprising nebuliser system and holding system, and aerosol administration method
MA52353A (fr) 2018-04-23 2021-04-28 Chiesi Farm Spa Combinaison thérapeutique comprenant un tensioactif pulmonaire et un stéroïde pour la prophylaxie de la dbp
EP3666316A1 (de) 2018-12-14 2020-06-17 PARI Pharma GmbH Aerosolabgabevorrichtung und verfahren zum betrieb der aerosolabgabevorrichtung
EP3666315A1 (de) 2018-12-14 2020-06-17 PARI Pharma GmbH Aerosolabgabevorrichtung und verfahren zum betrieb der aerosolabgabevorrichtung
EP3843105A1 (de) 2019-12-23 2021-06-30 PARI Pharma GmbH Steuerungsvorrichtung für aerosolzerstäubersystem
WO2021151853A1 (en) 2020-01-28 2021-08-05 Chiesi Farmaceutici S.P.A. Polypeptides having improved properties
EP4411745A1 (de) 2023-02-01 2024-08-07 Pari Medical Holding GmbH Medizinisches beurteilungsverfahren, aerosolzerstäuber und medizinisches beurteilungssystem
EP4464354A1 (de) 2023-05-15 2024-11-20 Pari Medical Holding GmbH Verfahren zum betreiben einer inhalationsvorrichtung, inhalationsvorrichtung und inhalationsvorrichtungssystem zur bereitstellung eines inhalationsverfahrens/ einer atemführung
EP4464236A1 (de) 2023-05-15 2024-11-20 Pari Medical Holding GmbH Verfahren zum betreiben einer inhalationsvorrichtung, inhalationsvorrichtung und inhalationsvorrichtungssystem zur bereitstellung von inhalationsverfahrensrückmeldung

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4562003A (en) * 1984-10-26 1985-12-31 California Biotechnology, Inc. Monoclonal antibodies against alveolar surfactant protein
US4659805A (en) * 1984-12-11 1987-04-21 California Biotechnology, Inc. Recombinant alveolar surfactant protein
US4933280A (en) * 1984-12-11 1990-06-12 California Biotechnology Inc. Recombinant DNA sequence encoding Alveolar Surfactant Protein
JPS63503222A (ja) * 1986-05-06 1988-11-24 サイオス　ノバ　インコーポレイテッド 肺の疎水性界面活性物質に結合した分子量６，０００ダルトンのタンパク質及びその多量体
WO1988003170A1 (en) * 1986-10-24 1988-05-05 Whitsett Jeffrey A Pulmonary hydrophobic surfactant-associated proteins
JP2602968B2 (ja) * 1987-11-04 1997-04-23 カリフォルニア バイオテクノロジー インコーポレイテッド 肺胞の界面活性タンパク類
US4861756A (en) * 1988-03-08 1989-08-29 Merrell Dow Pharmaceuticals Inc. Synthetic pulmonary surfactant

Also Published As

Publication number Publication date
EP0593094A2 (de) 1994-04-20
FI894187A0 (fi) 1989-09-05
EP0350506B1 (de) 2000-09-13
JPH11262389A (ja) 1999-09-28
DK439089D0 (da) 1989-09-05
EP0350506A4 (en) 1992-01-22
EP0350506A1 (de) 1990-01-17
JPH02502917A (ja) 1990-09-13
US5164369A (en) 1992-11-17
DE68929248D1 (de) 2000-10-19
WO1989006657A1 (en) 1989-07-27
DE68929287T2 (de) 2001-07-05
AU629233B2 (en) 1992-10-01
AU3960089A (en) 1989-08-11
DE68929248T2 (de) 2001-01-25
DE68929287D1 (de) 2001-04-19
DK174818B1 (da) 2003-12-01
DK439089A (da) 1989-09-05
FI102180B (fi) 1998-10-30
EP0593094B1 (de) 2001-03-14
JP3009690B2 (ja) 2000-02-14
FI102180B1 (fi) 1998-10-30
ATE196298T1 (de) 2000-09-15
EP0593094A3 (de) 1994-11-02

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time