ATE199833T1 - Ausgabeverfahren für fibrindichtungsmittel - Google Patents

Ausgabeverfahren für fibrindichtungsmittel

Info

Publication number
ATE199833T1
ATE199833T1 AT91902627T AT91902627T ATE199833T1 AT E199833 T1 ATE199833 T1 AT E199833T1 AT 91902627 T AT91902627 T AT 91902627T AT 91902627 T AT91902627 T AT 91902627T AT E199833 T1 ATE199833 T1 AT E199833T1
Authority
AT
Austria
Prior art keywords
thrombin
fibrin sealant
dispensing method
sealant dispensing
under conditions
Prior art date
Application number
AT91902627T
Other languages
English (en)
Inventor
Smith Brenda Morse
A Denise Turner
Robert T Mcnally
Original Assignee
Cryolife Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cryolife Inc filed Critical Cryolife Inc
Application granted granted Critical
Publication of ATE199833T1 publication Critical patent/ATE199833T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/00491—Surgical glue applicators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/00491—Surgical glue applicators
    • A61B2017/00495—Surgical glue applicators for two-component glue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22082—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Debugging And Monitoring (AREA)
  • External Artificial Organs (AREA)
AT91902627T 1990-01-03 1991-01-02 Ausgabeverfahren für fibrindichtungsmittel ATE199833T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/460,379 US5219328A (en) 1990-01-03 1990-01-03 Fibrin sealant delivery method
PCT/US1991/000003 WO1991009641A1 (en) 1990-01-03 1991-01-02 Fibrin sealant delivery method

Publications (1)

Publication Number Publication Date
ATE199833T1 true ATE199833T1 (de) 2001-04-15

Family

ID=23828479

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91902627T ATE199833T1 (de) 1990-01-03 1991-01-02 Ausgabeverfahren für fibrindichtungsmittel

Country Status (11)

Country Link
US (1) US5219328A (de)
EP (1) EP0509041B1 (de)
JP (1) JP3136157B2 (de)
KR (1) KR100197930B1 (de)
AT (1) ATE199833T1 (de)
AU (1) AU641472B2 (de)
CA (1) CA2072355C (de)
DE (1) DE69132563T2 (de)
ES (1) ES2155055T3 (de)
RU (1) RU2104701C1 (de)
WO (1) WO1991009641A1 (de)

Families Citing this family (161)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5318524A (en) * 1990-01-03 1994-06-07 Cryolife, Inc. Fibrin sealant delivery kit
US5108421A (en) * 1990-10-01 1992-04-28 Quinton Instrument Company Insertion assembly and method of inserting a vessel plug into the body of a patient
US6197325B1 (en) 1990-11-27 2001-03-06 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6559119B1 (en) 1990-11-27 2003-05-06 Loyola University Of Chicago Method of preparing a tissue sealant-treated biomedical material
US7208179B1 (en) 1990-11-27 2007-04-24 The American National Red Cross Methods for treating disease and forming a supplemented fibrin matrix
US6117425A (en) * 1990-11-27 2000-09-12 The American National Red Cross Supplemented and unsupplemented tissue sealants, method of their production and use
US6054122A (en) * 1990-11-27 2000-04-25 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US5403278A (en) * 1992-04-15 1995-04-04 Datascope Investment Corp. Device and method for treating hematomas and false aneurysms
DK83092D0 (da) * 1992-06-24 1992-06-24 Unes As Fremgangsmaade til udvinding af thrombin
US5413571A (en) * 1992-07-16 1995-05-09 Sherwood Medical Company Device for sealing hemostatic incisions
FR2696095B1 (fr) * 1992-09-30 1994-11-25 Inoteb Colle biologique à base de protéines coagulables par la thrombine, enrichie en facteurs plaquettaires, sa préparation et son application.
CN1091315A (zh) * 1992-10-08 1994-08-31 E·R·斯奎布父子公司 血纤维蛋白封闭剂组合物及其使用方法
US5552452A (en) * 1993-03-15 1996-09-03 Arch Development Corp. Organic tissue glue for closure of wounds
US5951531A (en) * 1993-04-20 1999-09-14 Medchem Products, Inc. Apparatus and method for applying a particulate hemostatic agent to living tissue
US6017359A (en) 1993-05-25 2000-01-25 Vascular Solutions, Inc. Vascular sealing apparatus
US5383896A (en) * 1993-05-25 1995-01-24 Gershony; Gary Vascular sealing device
US5795780A (en) * 1993-06-23 1998-08-18 Bristol-Myers Squibb Company Method of use of autologous thrombin blood fraction in a cell culture with keratinocytes
US5759194A (en) * 1993-09-28 1998-06-02 Hemodynamics, Inc. Vascular patch applicator
US5653730A (en) * 1993-09-28 1997-08-05 Hemodynamics, Inc. Surface opening adhesive sealer
US5843124A (en) * 1993-09-28 1998-12-01 Hemodynamics, Inc. Surface opening adhesive sealer
US6302898B1 (en) 1994-06-24 2001-10-16 Advanced Closure Systems, Inc. Devices for sealing punctures in body vessels
US6033401A (en) 1997-03-12 2000-03-07 Advanced Closure Systems, Inc. Vascular sealing device with microwave antenna
US5660873A (en) * 1994-09-09 1997-08-26 Bioseal, Limited Liability Corporaton Coating intraluminal stents
US5585007A (en) 1994-12-07 1996-12-17 Plasmaseal Corporation Plasma concentrate and tissue sealant methods and apparatuses for making concentrated plasma and/or tissue sealant
US20020131933A1 (en) * 1996-01-16 2002-09-19 Yves Delmotte Biopolymer membrane and methods for its preparation
US6965014B1 (en) * 1996-01-16 2005-11-15 Baxter International Inc. Fibrin material and method for producing and using the same
US5649959A (en) * 1995-02-10 1997-07-22 Sherwood Medical Company Assembly for sealing a puncture in a vessel
US5674394A (en) * 1995-03-24 1997-10-07 Johnson & Johnson Medical, Inc. Single use system for preparation of autologous plasma
US6217603B1 (en) 1997-08-29 2001-04-17 Closure Medical Corporation Methods of applying monomeric compositions effective as wound closure devices
US5928611A (en) * 1995-06-07 1999-07-27 Closure Medical Corporation Impregnated applicator tip
US20020018689A1 (en) * 1995-06-07 2002-02-14 Badejo Ibraheem T. Adhesive applicators with improved polymerization initiators
US6676322B1 (en) * 1995-06-07 2004-01-13 Closure Medical Corporation Impregnated applicator tip
AU7398196A (en) * 1995-10-11 1997-04-30 Fusion Medical Technologies, Inc. Device and method for sealing tissue
DE29723807U1 (de) * 1996-04-30 1999-11-04 Medtronic, Inc., Minneapolis, Minn. Autologe Fibrin-Blutstillungsmittel
WO2000062828A1 (en) * 1996-04-30 2000-10-26 Medtronic, Inc. Autologous fibrin sealant and method for making the same
EP0863725B1 (de) 1996-08-06 2007-10-17 St. Jude Medical Puerto Rico B.V. Einführungsvorrichtung zum einführen eines hemostatischen verschlusses in einen einschnitt
US8603511B2 (en) 1996-08-27 2013-12-10 Baxter International, Inc. Fragmented polymeric compositions and methods for their use
US7435425B2 (en) * 2001-07-17 2008-10-14 Baxter International, Inc. Dry hemostatic compositions and methods for their preparation
US7871637B2 (en) 1996-08-27 2011-01-18 Baxter International Inc. Dry hemostatic compositions and methods for their preparation
US8303981B2 (en) 1996-08-27 2012-11-06 Baxter International Inc. Fragmented polymeric compositions and methods for their use
US6066325A (en) * 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US6063061A (en) * 1996-08-27 2000-05-16 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
WO1998012274A1 (en) 1996-09-23 1998-03-26 Chandrashekar Pathak Methods and devices for preparing protein concentrates
US6566406B1 (en) 1998-12-04 2003-05-20 Incept, Llc Biocompatible crosslinked polymers
US8003705B2 (en) 1996-09-23 2011-08-23 Incept Llc Biocompatible hydrogels made with small molecule precursors
US20090324721A1 (en) 1996-09-23 2009-12-31 Jack Kennedy Hydrogels Suitable For Use In Polyp Removal
US5844087A (en) * 1996-11-05 1998-12-01 Bayer Corporation Method and device for delivering fibrin glue
US6733515B1 (en) 1997-03-12 2004-05-11 Neomend, Inc. Universal introducer
EP0993311B1 (de) 1997-06-18 2012-11-14 Angiotech Pharmaceuticals (US), Inc. Thrombin und mikrofibrillares collagen enthaltene zusammensetzung sowie herstellungsmethoden und dessen gebrauch
US6168788B1 (en) 1997-09-26 2001-01-02 Leon Wortham Fibrin glue without fibrinogen and biosealant compositions and methods
US6033427A (en) * 1998-01-07 2000-03-07 Lee; Benjamin I. Method and device for percutaneous sealing of internal puncture sites
US6762336B1 (en) 1998-01-19 2004-07-13 The American National Red Cross Hemostatic sandwich bandage
US20050196431A1 (en) * 1998-04-30 2005-09-08 Upvan Narang Adhesive applicator tip with a polymerization initiator, polymerization rate modifier, and/or bioactive material
US6274090B1 (en) 1998-08-05 2001-08-14 Thermogenesis Corp. Apparatus and method of preparation of stable, long term thrombin from plasma and thrombin formed thereby
SE9802938D0 (sv) * 1998-09-01 1998-09-01 Astra Ab Improved stability for injection solutions
US6310036B1 (en) 1999-01-09 2001-10-30 Last Chance Tissue Adhesives Corporation High strength, Bio-compatible tissue adhesive and methods for treating vigorously bleeding surfaces
US6472162B1 (en) 1999-06-04 2002-10-29 Thermogenesis Corp. Method for preparing thrombin for use in a biological glue
DE29911689U1 (de) * 1999-07-06 2000-04-06 Sterk, Peter, Dr., 88212 Ravensburg Mittel für den Gefässverschluß von organischem Gewebe
US20050049178A1 (en) * 1999-07-06 2005-03-03 Oberschwabenklinik Gmbh Agent for the occlusion of blood vessels
US6428233B1 (en) 2000-01-07 2002-08-06 Closure Medical Corporation Adhesive applicator tips with improved flow properties
US6428234B1 (en) 2000-01-07 2002-08-06 Closure Medical Corporation Adhesive applicator tips with improved flow properties
US6425704B2 (en) 2000-01-07 2002-07-30 Closure Medical Corporation Adhesive applicators with improved applicator tips
DE10012732A1 (de) * 2000-03-18 2001-09-20 Aventis Behring Gmbh Thrombin-Zubereitungen und Verfahren zu ihrer Herstellung
US20030209612A1 (en) * 2000-07-17 2003-11-13 Kevin Hahnen Spray head for applying a multi-component mixture
US6648911B1 (en) 2000-11-20 2003-11-18 Avantec Vascular Corporation Method and device for the treatment of vulnerable tissue site
RU2187347C1 (ru) * 2001-01-12 2002-08-20 Государственный научный центр Российской Федерации "НИОПИК" Способ фотодинамической терапии и аппликатор для его осуществления
JP4680483B2 (ja) 2001-02-23 2011-05-11 ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 組織および臓器の治療および修復に用いるための幹細胞マトリックスの迅速な調製方法
EP1407780B1 (de) 2001-07-10 2013-05-01 The Chemo-Sero-Therapeutic Research Institute Pharmazeutisch stabile hämostatische zusammensetzungen
US6616019B2 (en) 2001-07-18 2003-09-09 Closure Medical Corporation Adhesive applicator with improved applicator tip
EP1465521A4 (de) 2001-11-01 2008-10-08 Spine Wave Inc System und verfahren zur vorbehandlung der endplatten einer bandscheibe
JP3993855B2 (ja) * 2001-11-01 2007-10-17 スパイン・ウェイブ・インコーポレーテッド 脊椎椎間板の回復のための装置
US7179391B2 (en) 2002-05-24 2007-02-20 Biomet Manufacturing Corp. Apparatus and method for separating and concentrating fluids containing multiple components
US7992725B2 (en) 2002-05-03 2011-08-09 Biomet Biologics, Llc Buoy suspension fractionation system
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
US7374678B2 (en) 2002-05-24 2008-05-20 Biomet Biologics, Inc. Apparatus and method for separating and concentrating fluids containing multiple components
US20030205538A1 (en) 2002-05-03 2003-11-06 Randel Dorian Methods and apparatus for isolating platelets from blood
US20060278588A1 (en) 2002-05-24 2006-12-14 Woodell-May Jennifer E Apparatus and method for separating and concentrating fluids containing multiple components
US7845499B2 (en) 2002-05-24 2010-12-07 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
AU2003270401B2 (en) 2002-09-10 2008-03-13 American National Red Cross Hemostatic dressing
US8834864B2 (en) * 2003-06-05 2014-09-16 Baxter International Inc. Methods for repairing and regenerating human dura mater
US7927626B2 (en) * 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
EP1729672A2 (de) * 2004-01-08 2006-12-13 Spine Wave, Inc. Vorrichtung und verfahren zum injizieren von fliessendem material an einer auseinandergezogenen gewebestelle
US7789913B2 (en) * 2004-06-29 2010-09-07 Spine Wave, Inc. Methods for injecting a curable biomaterial into an intervertebral space
US7597687B2 (en) * 2004-10-29 2009-10-06 Spinal Restoration, Inc. Injection of fibrin sealant including an anesthetic in spinal applications
US8206448B2 (en) * 2004-10-29 2012-06-26 Spinal Restoration, Inc. Injection of fibrin sealant using reconstituted components in spinal applications
CA2574773A1 (en) * 2004-07-22 2006-02-02 Allan D. Pronovost Compositions and methods for treating excessive bleeding
US20110213464A1 (en) * 2004-10-29 2011-09-01 Whitlock Steven I Injection of fibrin sealant in the absence of corticosteroids in spinal applications
US7866485B2 (en) 2005-02-07 2011-01-11 Hanuman, Llc Apparatus and method for preparing platelet rich plasma and concentrates thereof
EP2666494B1 (de) 2005-02-07 2018-01-17 Hanuman LLC Vorrichtung und Verfahren für blutplättchenreiches Plasmakonzentrat
WO2006086201A2 (en) 2005-02-07 2006-08-17 Hanuman Llc Platelet rich plasma concentrate apparatus and method
EP1846505B1 (de) 2005-02-09 2015-11-11 Covidien LP Synthetische dichtungsmittel
US7766900B2 (en) 2005-02-21 2010-08-03 Biomet Manufacturing Corp. Method and apparatus for application of a fluid
WO2007127198A2 (en) 2006-04-24 2007-11-08 Incept, Llc Protein crosslinkers, crosslinking methods and applications thereof
US8567609B2 (en) 2006-05-25 2013-10-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
MX2008014847A (es) * 2006-05-31 2009-04-30 Baxter Int Metodo para crecimiento interno en la celula dirigido y regeneracion controlada de los tejidos en la cirugia espinal.
TWI436793B (zh) * 2006-08-02 2014-05-11 巴克斯特國際公司 快速作用之乾密封膠及其使用和製造方法
US20080033333A1 (en) * 2006-08-04 2008-02-07 Macphee Martin Solid dressing for treating wounded tissue
US8328024B2 (en) 2007-04-12 2012-12-11 Hanuman, Llc Buoy suspension fractionation system
WO2008127639A1 (en) 2007-04-12 2008-10-23 Biomet Biologics, Llc Buoy suspension fractionation system
US20090075891A1 (en) * 2007-08-06 2009-03-19 Macphee Martin Methods and dressings for sealing internal injuries
US8067028B2 (en) 2007-08-13 2011-11-29 Confluent Surgical Inc. Drug delivery device
TWI461227B (zh) 2007-10-30 2014-11-21 Baxter Int 再生生物功能性膠原生物基質用來治療內臟或體壁缺陷的用途
US20090117188A1 (en) * 2007-11-02 2009-05-07 Gershkovich Julia B Methods of Augmenting or Repairing Soft Tissue
PL2259774T3 (pl) 2008-02-27 2013-04-30 Biomet Biologics Llc Sposoby i kompozycje dla wprowadzania antagonisty receptora interleukiny-1
EP2259803B2 (de) 2008-02-29 2019-03-13 Ferrosan Medical Devices A/S Vorrichtung zur förderung von hämostase und/oder wundheilung
US8337711B2 (en) 2008-02-29 2012-12-25 Biomet Biologics, Llc System and process for separating a material
US8518272B2 (en) 2008-04-04 2013-08-27 Biomet Biologics, Llc Sterile blood separating system
US9839772B2 (en) 2008-05-06 2017-12-12 Cook Medical Technologies Llc Apparatus and methods for delivering therapeutic agents
US8012077B2 (en) 2008-05-23 2011-09-06 Biomet Biologics, Llc Blood separating device
CA2747390C (en) 2008-12-23 2016-10-04 Wilson-Cook Medical Inc. Apparatus and methods for containing and delivering therapeutic agents
US8187475B2 (en) 2009-03-06 2012-05-29 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US8313954B2 (en) 2009-04-03 2012-11-20 Biomet Biologics, Llc All-in-one means of separating blood components
US9039783B2 (en) 2009-05-18 2015-05-26 Baxter International, Inc. Method for the improvement of mesh implant biocompatibility
US8118777B2 (en) 2009-05-29 2012-02-21 Cook Medical Technologies Llc Systems and methods for delivering therapeutic agents
US9101744B2 (en) 2009-05-29 2015-08-11 Cook Medical Technologies Llc Systems and methods for delivering therapeutic agents
WO2010146582A2 (en) * 2009-06-15 2010-12-23 Technion- Research And Development Foundation Ltd. Reinforced surgical adhesives and sealants and their in-situ application
ES2532428T3 (es) 2009-06-16 2015-03-26 Baxter International Inc Esponja hemostática
US9011800B2 (en) 2009-07-16 2015-04-21 Biomet Biologics, Llc Method and apparatus for separating biological materials
US20120141587A1 (en) * 2009-08-25 2012-06-07 Dale Yoo Compositions and methods for treatment or prevention of post-operative organ or tissue inflammation
MX2012007056A (es) 2009-12-16 2012-09-28 Baxter Healthcare Sa Esponja hemostatica.
SA111320355B1 (ar) 2010-04-07 2015-01-08 Baxter Heathcare S A إسفنجة لايقاف النزف
US8591391B2 (en) 2010-04-12 2013-11-26 Biomet Biologics, Llc Method and apparatus for separating a material
EP2575775B1 (de) 2010-06-01 2018-04-04 Baxter International Inc. Verfahren zur herstellung von trockenen und stabilen hämostatischen zusammensetzungen
JP6289096B2 (ja) 2010-06-01 2018-03-07 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ 乾燥した安定な止血組成物を作製するためのプロセス
WO2011151386A1 (en) 2010-06-01 2011-12-08 Baxter International Inc. Process for making dry and stable hemostatic compositions
US8440309B2 (en) 2011-01-31 2013-05-14 Confluent Surgical, Inc. Crosslinked polymers with the crosslinker as therapeutic for sustained release
WO2012127328A1 (en) 2011-03-24 2012-09-27 Sofradim Production Enzymatically degradable compositions
AU2012318258B2 (en) 2011-10-11 2015-07-09 Baxter Healthcare S.A. Hemostatic compositions
EP4137165A1 (de) 2011-10-11 2023-02-22 Baxter International Inc. Hämostatische zusammensetzungen
WO2013060770A1 (en) 2011-10-27 2013-05-02 Baxter International Inc. Hemostatic compositions
US8999376B2 (en) 2012-02-03 2015-04-07 Xcede Technologies, Inc. Tissue patch
RU2657955C2 (ru) 2012-03-06 2018-06-18 Ферросан Медикал Дивайсиз А/С Контейнер под давлением, содержащий гемостатическую пасту
RU2636240C2 (ru) 2012-06-12 2017-11-21 Ферросан Медикал Дивайсиз А/С Сухая гемостатическая композиция
US9642956B2 (en) 2012-08-27 2017-05-09 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US10016527B2 (en) 2012-10-23 2018-07-10 Orthovita, Inc. Materials and methods for repair of cartilage defects
US10208095B2 (en) 2013-03-15 2019-02-19 Biomet Manufacturing, Llc Methods for making cytokine compositions from tissues using non-centrifugal methods
US11931227B2 (en) 2013-03-15 2024-03-19 Cook Medical Technologies Llc Bimodal treatment methods and compositions for gastrointestinal lesions with active bleeding
US9867931B2 (en) 2013-10-02 2018-01-16 Cook Medical Technologies Llc Therapeutic agents for delivery using a catheter and pressure source
US10143725B2 (en) 2013-03-15 2018-12-04 Biomet Biologics, Llc Treatment of pain using protein solutions
US20140271589A1 (en) 2013-03-15 2014-09-18 Biomet Biologics, Llc Treatment of collagen defects using protein solutions
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US9950035B2 (en) 2013-03-15 2018-04-24 Biomet Biologics, Llc Methods and non-immunogenic compositions for treating inflammatory disorders
CN105358071B (zh) 2013-06-21 2018-07-31 弗罗桑医疗设备公司 真空膨胀的干组合物和用于保留该干组合物的注射器
WO2015086028A1 (en) 2013-12-11 2015-06-18 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
IL230150A0 (en) 2013-12-24 2014-09-30 Omrix Biopharmaceuticals Ltd One-component fibrin glue containing zymogens
IL230151A0 (en) 2013-12-24 2014-09-30 Omrix Biopharmaceuticals Ltd One-component fibrin glue containing a polymerization inhibitor
IL231792A0 (en) 2014-03-27 2014-08-31 Omrix Biopharmaceuticals Ltd Device and method for the preparation and administration of one-component fibrin glue
US11046818B2 (en) 2014-10-13 2021-06-29 Ferrosan Medical Devices A/S Dry composition for use in haemostasis and wound healing
CN107206165B (zh) 2014-12-24 2020-10-23 弗罗桑医疗设备公司 用于保持并混合第一和第二物质的注射器
US9713810B2 (en) 2015-03-30 2017-07-25 Biomet Biologics, Llc Cell washing plunger using centrifugal force
EA026104B1 (ru) * 2015-04-02 2017-03-31 Общество С Ограниченной Ответственностью "Тектум" Кровоостанавливающее и ранозаживляющее средство
US9757721B2 (en) 2015-05-11 2017-09-12 Biomet Biologics, Llc Cell washing plunger using centrifugal force
CA2986981A1 (en) 2015-07-03 2017-01-12 Ferrosan Medical Devices A/S Syringe for mixing two components and for retaining a vacuum in a storage condition
US9833538B2 (en) 2015-08-07 2017-12-05 Xcede Technologies, Inc. Adhesive compositions and related methods
US9540548B1 (en) 2015-08-07 2017-01-10 Xcede Technologies, Inc. Adhesive compositions and related methods
WO2017027378A1 (en) 2015-08-07 2017-02-16 Xcede Technologies, Inc. Adhesive compositions and related methods
EP3790600B1 (de) 2018-05-09 2023-12-27 Ferrosan Medical Devices A/S Verfahren zur herstellung einer hämostatischen zusammensetzung
EP3934542B1 (de) 2019-03-06 2025-04-23 Gambro Lundia AB Vorrichtung und verfahren zur abgabe eines thrombinaktivierten fibrinversiegelers
BR112022023464A2 (pt) 2020-06-05 2022-12-20 Cook Medical Technologies Llc Endoscópios médicos para entregar agentes terapêuticos
US12543936B2 (en) 2021-07-14 2026-02-10 Cook Medical Technologies Llc Systems and methods for preventing clogging of a delivery system
US12496429B2 (en) 2022-10-18 2025-12-16 Cook Medical Technologies Llc Systems and methods for delivering pressurized fluid to a target site alone or in conjunction with therapeutic agents

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2533004A (en) * 1943-10-27 1950-12-05 John D Ferry Fibrin clots and methods for preparing the same
US2492458A (en) * 1944-12-08 1949-12-27 Jr Edgar A Bering Fibrin foam
US3723244A (en) * 1971-01-18 1973-03-27 Atomic Energy Commission Fibrous fibrin sheet and method for producing same
US4265233A (en) * 1978-04-12 1981-05-05 Unitika Ltd. Material for wound healing
AT359653B (de) * 1979-02-15 1980-11-25 Immuno Ag Verfahren zur herstellung eines gewebekleb- stoffes
AT366916B (de) * 1980-04-02 1982-05-25 Immuno Ag Vorrichtung zur applikation eines gewebeklebstoffes auf basis von menschlichen oder tierischenproteinen
US4359463A (en) * 1980-11-26 1982-11-16 Rock Gail A Stabilization of Factor VIII activity in whole blood or blood plasma
DE3105624A1 (de) * 1981-02-16 1982-09-02 Hormon-Chemie München GmbH, 8000 München Material zum abdichten und heilen von wunden
FR2505587A1 (fr) * 1981-05-08 1982-11-12 Trt Telecom Radio Electr Dispositif destine a eviter des oscillations entretenues genantes dans un systeme boucle
ATE13810T1 (de) * 1981-06-25 1985-07-15 Serapharm Gmbh & Co Kg Angereichertes plasmaderivat zur unterstuetzung von wundverschluss und wundabdeckung.
US4442655A (en) * 1981-06-25 1984-04-17 Serapharm Michael Stroetmann Fibrinogen-containing dry preparation, manufacture and use thereof
AT379311B (de) * 1984-03-29 1985-12-27 Immuno Ag Vorrichtung zur applikation eines gewebeklebstoffes
JPS6144825A (ja) * 1984-08-09 1986-03-04 Unitika Ltd 止血剤
US4627879A (en) * 1984-09-07 1986-12-09 The Trustees Of Columbia University In The City Of New York Fibrin adhesive prepared as a concentrate from single donor fresh frozen plasma
AT382783B (de) * 1985-06-20 1987-04-10 Immuno Ag Vorrichtung zur applikation eines gewebeklebstoffes
US4696812A (en) * 1985-10-28 1987-09-29 Warner-Lambert Company Thrombin preparations
DE3622642A1 (de) * 1986-07-05 1988-01-14 Behringwerke Ag Einkomponenten-gewebekleber sowie verfahren zu seiner herstellung
US4902281A (en) * 1988-08-16 1990-02-20 Corus Medical Corporation Fibrinogen dispensing kit

Also Published As

Publication number Publication date
JP3136157B2 (ja) 2001-02-19
DE69132563T2 (de) 2001-10-31
WO1991009641A1 (en) 1991-07-11
AU641472B2 (en) 1993-09-23
EP0509041A1 (de) 1992-10-21
AU7173391A (en) 1991-07-24
EP0509041A4 (en) 1993-10-13
CA2072355C (en) 2001-05-15
ES2155055T3 (es) 2001-05-01
US5219328A (en) 1993-06-15
RU2104701C1 (ru) 1998-02-20
KR100197930B1 (ko) 1999-06-15
DE69132563D1 (de) 2001-04-26
CA2072355A1 (en) 1991-07-04
KR927003146A (ko) 1992-12-17
JPH05504950A (ja) 1993-07-29
EP0509041B1 (de) 2001-03-21

Similar Documents

Publication Publication Date Title
ATE199833T1 (de) Ausgabeverfahren für fibrindichtungsmittel
ATE15143T1 (de) Material zum abdichten und heilen von wunden und verfahren zu dessen herstellung.
DE3866817D1 (de) Knochenzement zur kontrollierten abgabe von wirkstoffen.
MX9603285A (es) Concentrado de plasma y composiciones obturadoras de tejido y metodos y aparatos para preparar el concentrado de plasma y/o el obturador de tejido para sellar el tejido, para la separacion rapida de particulas de suspensiones y para la concentracion
DE69734557D1 (de) Sprühvorrichtung zum aufbringen von gewebeklebstoff
EP0341007A3 (en) Surgical adhesive material
CA2182862A1 (en) Plasma concentrate and tissue sealant compositions
ATE20824T1 (de) Angereichertes plasmaderivat zur unterstuetzung von wundverschluss und wundheilung.
NO20002357L (no) Fibrin-tetningsmidler eller -ad-hesiver inneholdende et hyaluronsyrederivat-materiale
ATE262833T1 (de) Vorrichtung zum auftragen von fibrinkleber
DE60027266D1 (de) Vorrichtung zur aufbereitung einer medizinischen flüssigkeit
DE3473407D1 (en) Method of inactivating pathogens
ATE110578T1 (de) Von hydrogel angetriebene verabreichungsvorrichtung.
ES8304800A1 (es) "procedimiento de preparacion de una composicion terapeutica en la que el unico agente hemostatico activado efectivo sea el factor viia".
ATE103564T1 (de) Verpackung zur aufnahme und mischung von zwei komponenten.
ATE187651T1 (de) Zweikomponenten-fibrinkleber
IT1214710B (it) Composizione detergente per bucato non ionica,liquida e non acquosa senza fosfato o a bassa concentrazione di fosfato ,e procedimento di impiego
EP0230273A3 (en) Bottle for mixing and method of mixing with the said bottle
DE3577745D1 (de) Verfahren und geraet zur untersuchung von fluessigkeit in einer rohrleitung.
BR9810242A (pt) Composições úteis como selante de fibrina
ATE48587T1 (de) Mittel zur entschwefelnden reinigung von karbonatsteinoberflaechen.
Kram et al. Use of concentrated fibrinogen in experimental splenic trauma
ATE50520T1 (de) Verfahren zum behandeln von naegeln.
PT83322B (pt) Processo para a preparacao de composicoes farmaceuticas para tratamento da hipertensao do sangue contendo um inibidor da enzima de conversao da angiotensina em mistura sinergica com um agente diuretico de laco
JPS6425843A (en) Apparatus for applying living body adhesive

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee