ATE203916T1 - Biotherapeutische mikrosphären beschichtet mit zellen - Google Patents

Biotherapeutische mikrosphären beschichtet mit zellen

Info

Publication number
ATE203916T1
ATE203916T1 AT93911706T AT93911706T ATE203916T1 AT E203916 T1 ATE203916 T1 AT E203916T1 AT 93911706 T AT93911706 T AT 93911706T AT 93911706 T AT93911706 T AT 93911706T AT E203916 T1 ATE203916 T1 AT E203916T1
Authority
AT
Austria
Prior art keywords
pct
skin
date nov
microspheres
sec
Prior art date
Application number
AT93911706T
Other languages
English (en)
Inventor
David W Armstrong
Original Assignee
Ca Nat Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ca Nat Research Council filed Critical Ca Nat Research Council
Application granted granted Critical
Publication of ATE203916T1 publication Critical patent/ATE203916T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11Encapsulated compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A61K8/985Skin or skin outgrowth, e.g. hair, nails
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60Materials for use in artificial skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0697Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C12N5/0698Skin equivalents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41Particular ingredients further characterized by their size
    • A61K2800/412Microsized, i.e. having sizes between 0.1 and 100 microns
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/09Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
    • C12N2502/094Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/13Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323Adult fibroblasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2531/00Microcarriers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/30Synthetic polymers
    • C12N2533/40Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Birds (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT93911706T 1992-05-18 1993-04-23 Biotherapeutische mikrosphären beschichtet mit zellen ATE203916T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929210574A GB9210574D0 (en) 1992-05-18 1992-05-18 Biotherapeutic cell-coated microspheres for wound/burn and prothesis implant applications
PCT/CA1993/000187 WO1993023088A1 (en) 1992-05-18 1993-04-23 Biotherapeutic cell-coated microspheres

Publications (1)

Publication Number Publication Date
ATE203916T1 true ATE203916T1 (de) 2001-08-15

Family

ID=10715656

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93911706T ATE203916T1 (de) 1992-05-18 1993-04-23 Biotherapeutische mikrosphären beschichtet mit zellen

Country Status (16)

Country Link
US (1) US5830507A (de)
EP (1) EP0641223B1 (de)
JP (1) JP2820796B2 (de)
KR (1) KR950701533A (de)
AT (1) ATE203916T1 (de)
BR (1) BR9306375A (de)
CA (1) CA2135999C (de)
DE (1) DE69330562T2 (de)
DK (1) DK0641223T3 (de)
ES (1) ES2161229T3 (de)
GB (1) GB9210574D0 (de)
GR (1) GR3036741T3 (de)
NZ (1) NZ252661A (de)
PT (1) PT641223E (de)
RU (1) RU2104039C1 (de)
WO (1) WO1993023088A1 (de)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5654267A (en) * 1988-12-20 1997-08-05 La Jolla Cancer Research Center Cooperative combinations of ligands contained within a matrix
IL115728A0 (en) * 1994-10-25 1996-01-19 Boehringer Mannheim Gmbh Biomaterial containing epithelial cells and use thereof as a transplant
IL118376A0 (en) 1996-05-22 1996-09-12 Univ Ben Gurion Polysaccharide sponges for cell culture and transplantation
US20020037566A1 (en) * 1997-04-16 2002-03-28 Rees Riley S. Cell-coated supports
US5972332A (en) * 1997-04-16 1999-10-26 The Regents Of The University Of Michigan Wound treatment with keratinocytes on a solid support enclosed in a porous material
US5861149A (en) * 1997-06-04 1999-01-19 Polyheal Ltd. Methods for wound treatment
WO1999021963A1 (de) * 1997-10-25 1999-05-06 Roche Diagnostics Gmbh Autodegradable microcarriers and their use
CN1171635C (zh) * 1998-03-07 2004-10-20 株式会社大熊制药 含有人表皮生长因子的局部用组合物
US6378527B1 (en) * 1998-04-08 2002-04-30 Chondros, Inc. Cell-culture and polymer constructs
IL139030A0 (en) * 1998-04-17 2001-11-25 Angiogenix Inc Therapeutic angiogenic factors and methods for their use
NZ506944A (en) * 1998-04-17 2003-10-31 Nestle Sa Immortalised keratinocyte cell line derived from normal human skin tissues
KR100683603B1 (ko) * 1998-10-23 2007-02-20 폴리힐 엘티디. 창상 치유용 미소구 조성물
RU2195889C2 (ru) * 1999-05-24 2003-01-10 Парамонов Борис Алексеевич Способ дермабразии
DE19937102A1 (de) * 1999-08-06 2001-02-15 Universitaetsklinikum Freiburg Gewebeersatz und Verfahren zu seiner Herstellung
US7056503B2 (en) * 1999-08-19 2006-06-06 Regents Of The University Of Michigan Enclosures housing cell-coated supports for treating tumors
DE19949290A1 (de) * 1999-10-12 2001-04-26 Albrecht Bettermann Partikuläres Konstrukt zur Verwendung in der Transplantationsmedizin
RU2184491C2 (ru) * 2000-03-10 2002-07-10 Озерская Ольга Сергеевна Способ устранения косметических дефектов кожного покрова
KR20010110945A (ko) 2000-06-09 2001-12-15 김정용 음경 확대 방법
RU2184492C2 (ru) * 2000-06-13 2002-07-10 Озерская Ольга Сергеевна Способ дерматохирургического лечения гипотрофических рубцов
US6719970B1 (en) * 2000-07-10 2004-04-13 Alkermes Controlled Therapeutics, Inc. Method of generating cartilage
US20030148924A1 (en) * 2002-07-09 2003-08-07 Tamar Tennenbaum Methods and pharmaceutical compositions of healing wounds
US20100129332A1 (en) * 2000-07-31 2010-05-27 Tamar Tennenbaum Methods and pharmaceutical compositions for healing wounds
US20040037828A1 (en) 2002-07-09 2004-02-26 Bar-Ilan University Methods and pharmaceutical compositions for healing wounds
US20060258562A1 (en) * 2000-07-31 2006-11-16 Healor Ltd. Methods and pharmaceutical compositions for healing wounds
JP2002281964A (ja) * 2000-12-26 2002-10-02 Sanyo Chem Ind Ltd 細胞生産方法
AUPR289601A0 (en) * 2001-02-05 2001-03-01 Commonwealth Scientific And Industrial Research Organisation Method of tissue repair
RU2223790C2 (ru) * 2001-10-25 2004-02-20 ГФУН "Российский научно-исследовательский институт травматологии и ортопедии им. Р.Р. Вредена" Способ стерилизации биологических трансплантатов окисью этилена в жидкой среде
FR2839260B1 (fr) * 2002-05-03 2005-02-25 Inst Nat Sante Rech Med Microparticules a base d'un materiau bicompatible et biodegradable, supportant des cellules et des substances biologiquement actives
US20050129776A1 (en) * 2002-05-03 2005-06-16 Inserm Microparticles supporting cells and active substances
US7402323B2 (en) * 2002-08-21 2008-07-22 Akpharma, Inc. Compositions and methods for treating skin conditions
RU2210389C1 (ru) * 2002-09-10 2003-08-20 Общество с ограниченной ответственностью "Мединтер Плюс" Спасательное покрывало
EP1635782A1 (de) * 2003-05-24 2006-03-22 JUVENA (International) AG Gewebekulturmedien als bestandteil von kosmetika
EP1636350B1 (de) * 2003-06-23 2007-09-12 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zur differenzierung von stammzellen in zellen, die ein pankreatisches hormon produzieren
NZ588743A (en) * 2003-07-15 2012-05-25 Univ Bar Ilan Use of a protein kinase C (PKC) alpha inhibitor for treating inflammation of the skin
WO2005013885A2 (en) * 2003-08-07 2005-02-17 Healor Ltd. Pharmaceutical compositions and methods for accelerating wound healing
RU2240809C1 (ru) * 2003-08-26 2004-11-27 Государственное учреждение "Нижегородский научно-исследовательский институт травматологии и ортопедии" Способ получения бесклеточного дермального матрикса
KR20060109908A (ko) * 2003-10-20 2006-10-23 가부시키가이샤 제이.에무.에스 세포 취급 장치, 조직 재생용 조성물 및 조직 재생 방법
EP2462944A3 (de) 2005-08-29 2012-09-12 HealOr Ltd. Verfahren und Zusammensetzungen zur Vorbeugung und Behandlung von diabetischer und alternder Haut
RU2316290C2 (ru) * 2005-11-21 2008-02-10 Институт биохимии им. А.Н. Баха РАН Сетчатый эндопротез для восстановительной хирургии
WO2008073614A2 (en) * 2006-11-02 2008-06-19 Akpharma Inc. Composition and method for enhancing skin cell growth, proliferation and repair
KR100805208B1 (ko) 2007-03-27 2008-02-21 주식회사 펩트론 엑센딘 함유 서방성 제제 조성물, 엑센딘 함유 서방성미립구 및 이의 제조 방법
US20100255070A1 (en) * 2007-05-22 2010-10-07 Prelief Inc. Compositions and methods for preventing, minimizing and healing skin irritation and trauma
CN102755649A (zh) * 2007-07-30 2012-10-31 希尔洛有限公司 药物组合物及相关方法
WO2009043052A1 (en) * 2007-09-27 2009-04-02 Columbia University Methods and systems for forming biocompatible materials
US8613776B2 (en) * 2007-12-27 2013-12-24 The Trustees Of Columbia University In The City Of New York Systems and methods for forming patterned extracellular matrix materials
US9095569B2 (en) 2008-04-18 2015-08-04 Collplant Ltd. Methods of generating and using procollagen
WO2009150883A1 (ja) 2008-06-13 2009-12-17 株式会社資生堂 皮膚代替膜、金型及び皮膚外用剤の評価方法
EA014044B1 (ru) * 2008-07-09 2010-08-30 Общество С Ограниченной Ответственностью "Аква-Альянс" Наносомальная лекарственная форма препарата пролонгированного действия для лечения гепатита с (варианты)
UA110776C2 (uk) * 2009-12-04 2016-02-25 Маґле Аб Мікросфера гідролізованого крохмалю з ендогенним зарядженим лігандом
JP2013516500A (ja) 2010-01-11 2013-05-13 ヒールオア・リミテッド 炎症性疾患および障害を治療するための方法
JP5241764B2 (ja) * 2010-03-31 2013-07-17 テルモ株式会社 生体適合性材料の評価方法
RU2616866C1 (ru) * 2015-12-31 2017-04-18 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Биорезорбируемый микроноситель для доставки клеток в область заживления и регенерации ран
RU2644633C1 (ru) * 2016-12-28 2018-02-13 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ восстановления кожного покрова
RU2658707C1 (ru) * 2016-12-28 2018-06-22 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ восстановления кожного покрова
CN110960513A (zh) * 2019-11-29 2020-04-07 苏州瑞微生物科技有限公司 一种微球阵列及其制备方法和用途
CN113201481B (zh) * 2021-04-19 2023-10-13 清华大学深圳国际研究生院 皮肤微球及其制备方法和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2461002A1 (fr) * 1979-07-13 1981-01-30 Inst Nat Sante Rech Med Procede pour stimuler la croissance des cellules d'epiderme humain et produits faisant application dudit procede
CA1215922A (en) * 1984-05-25 1986-12-30 Connaught Laboratories Limited Microencapsulation of living tissue and cells
DE3688168T2 (de) * 1985-08-14 1993-10-28 Memorial Hospital Cancer Epidermiszellenextrakte und Verfahren zur Verbesserung der Wundheilung und zur Regenerierung der Epidermis.
FR2597499A1 (fr) * 1986-04-18 1987-10-23 Merieux Inst Procede de culture microbiologique sur supports de collagene, supports pour ce procede et produits obtenus
NZ222413A (en) * 1986-11-05 1991-06-25 Ethicon Inc Compositions containing a polypeptide growth factor and a water-soluble cellulose polymer stabiliser
US5015584A (en) * 1987-10-14 1991-05-14 Board Of Regents, The University Of Texas System Epidermal graft system
GB8803697D0 (en) * 1988-02-17 1988-03-16 Deltanine Research Ltd Clinical developments using amniotic membrane cells
CA1307225C (en) * 1988-07-19 1992-09-08 David W. Armstrong Cell culture bioreactor
US5135915A (en) * 1988-10-14 1992-08-04 Genentech, Inc. Method for the treatment of grafts prior to transplantation using TGF-.beta.
DE69017820T2 (de) * 1989-04-25 1995-10-05 Children's Medical Center Corp., Boston, Mass. Implantaten für grosse mengen von zellen auf polymerische matrizen.
US4996154A (en) * 1989-05-04 1991-02-26 Millipore Corporation Method for growing cellular tissue
US5618531A (en) * 1990-10-19 1997-04-08 New York University Method for increasing the viability of cells which are administered to the brain or spinal cord

Also Published As

Publication number Publication date
BR9306375A (pt) 1997-03-04
PT641223E (pt) 2001-12-28
AU668959B2 (en) 1996-05-23
JPH07507063A (ja) 1995-08-03
KR100381207B1 (de) 2003-10-23
NZ252661A (en) 1996-09-25
KR950701533A (ko) 1995-04-28
RU94046192A (ru) 1996-10-10
US5830507A (en) 1998-11-03
WO1993023088A1 (en) 1993-11-25
DK0641223T3 (da) 2001-10-01
RU2104039C1 (ru) 1998-02-10
DE69330562T2 (de) 2002-05-29
EP0641223A1 (de) 1995-03-08
GB9210574D0 (en) 1992-07-01
EP0641223B1 (de) 2001-08-08
ES2161229T3 (es) 2001-12-01
CA2135999C (en) 1999-07-13
DE69330562D1 (de) 2001-09-13
JP2820796B2 (ja) 1998-11-05
AU4257993A (en) 1993-12-13
CA2135999A1 (en) 1993-11-25
GR3036741T3 (en) 2001-12-31

Similar Documents

Publication Publication Date Title
ATE203916T1 (de) Biotherapeutische mikrosphären beschichtet mit zellen
ATE125158T1 (de) Biologisch abbaubare und biologisch absorbierbare führungskanäle zur verwendung in der behandlung und regenerierung von nerven.
ZA943514B (en) The use of dihydrolipoic acid as an ophthalmological agent and to suppress intolerance reactions in the area between implants and living body tissue
DE69231796D1 (de) Verbundvliesstoff, enthaltend derivate von hyaluronsäure
DE69527203D1 (de) Wirkstoff zur stimulation von hartem gewebe
DE69627467D1 (de) Verwendung von zusammensetzungen mit benzoylperoxyd, glycolsäure und zink zur behandlung von dermatologischen krankheiten
DE68915540D1 (de) Für zellen eindringbares medizinisches material und kunsthaut.
RU94030735A (ru) Композиционная мембрана, способ ее получения и способ направленной регенерации тканей с ее применением
DE68905205D1 (de) Verwendung von igf-i zur herstellung eines praeparats fuer die behandlung und die verhuetung von nebeneffekten von hyperinsulinemia bei diabetikern behandelt mit insulin.
CA2213533A1 (en) Resorbable extracellular matrix for reconstruction of cartilage tissue
BR9907273A (pt) Prótese, artigo, válvura cardìaca protética, e, processos para produzir uma prótese para um paciente humano, para modificar um substrato, para associar células endoteliais com um substrato, para distribuir um artigos médico para uso por profissionais de cuidados com a saúde, e para produzir um material biocompatìvel
ATE492304T1 (de) Verwendung von dreidimensionalen prothesen, die hyaluronsäurederivate enthalten
ATE435030T1 (de) Heilung von wunden oder fibrotischen krankheiten unter verwendung von wenigstens einem agens gegen einen wachstumsfaktor
CA2322878A1 (en) Use of selegiline or desmethylselegiline for treating wounds, burns and dermatological damage
BR9606075A (pt) Processo de composição para uso médico
CA2130762A1 (en) Treatment of Disease and Conditions Associated with Macrophage Infiltration
CA2091134A1 (en) Therapeutic agent for threatened abortion
RU93038888A (ru) Салфетка из тканого углеродного материала
DE68909933D1 (de) Für zellen eindringbares medizinisches material und kunsthaut.
Wolf et al. Evaluation of biological dressings
JPS6434359A (en) Novel high performance medical patch
Arnst The latest from the labs: human skin
Benmeir et al. Use of buried skin implants after recurrent failure of conventional skin grafting in a massive burn: the renewal of an old technique
DE69732851D1 (de) Verwendung von dextrinsulfat zur behandlung von sehr vasculären tumoren
ES2188754T3 (es) Componente b como cicatrizante.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee