ATE204193T1 - Verfahren zur umkehrphasen-chromatographie - Google Patents
Verfahren zur umkehrphasen-chromatographieInfo
- Publication number
- ATE204193T1 ATE204193T1 AT96940098T AT96940098T ATE204193T1 AT E204193 T1 ATE204193 T1 AT E204193T1 AT 96940098 T AT96940098 T AT 96940098T AT 96940098 T AT96940098 T AT 96940098T AT E204193 T1 ATE204193 T1 AT E204193T1
- Authority
- AT
- Austria
- Prior art keywords
- column
- nonionic
- compound
- solvent
- passed
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000004366 reverse phase liquid chromatography Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 239000012535 impurity Substances 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- 239000002872 contrast media Substances 0.000 abstract 1
- 229940039231 contrast media Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003690 nonionic contrast media Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
- B01D15/3861—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography using an external stimulus
- B01D15/3876—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography using an external stimulus modifying the temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- C07C231/24—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
- B01D15/424—Elution mode
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IE950904 | 1995-12-01 | ||
| PCT/IE1996/000076 WO1997020609A1 (en) | 1995-12-01 | 1996-12-02 | Reversed phase chromatographic process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE204193T1 true ATE204193T1 (de) | 2001-09-15 |
Family
ID=11040978
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96940098T ATE204193T1 (de) | 1995-12-01 | 1996-12-02 | Verfahren zur umkehrphasen-chromatographie |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0863782B1 (de) |
| AT (1) | ATE204193T1 (de) |
| AU (1) | AU7707096A (de) |
| DE (1) | DE69614564T2 (de) |
| ES (1) | ES2162117T3 (de) |
| GB (1) | GB2321859B (de) |
| NO (1) | NO315186B1 (de) |
| WO (1) | WO1997020609A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997046299A1 (en) * | 1996-06-05 | 1997-12-11 | Mallinckrodt Medical Imaging-Ireland | Reversed phase chromatographic process |
| FR3084668A1 (fr) | 2018-08-02 | 2020-02-07 | Guerbet | Procede de preparation monotope de composes organo-iodes intermediaires a la synthese du ioversol |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5204005A (en) * | 1990-02-26 | 1993-04-20 | Mallinckrodt, Inc. | Reversed phase chromatographic process |
| IT1274027B (it) * | 1994-03-03 | 1997-07-14 | Zambon Spa | Processo per la preparazione e purificazione di mezzi di contrasto iodurati |
-
1996
- 1996-12-02 EP EP96940098A patent/EP0863782B1/de not_active Expired - Lifetime
- 1996-12-02 WO PCT/IE1996/000076 patent/WO1997020609A1/en not_active Ceased
- 1996-12-02 DE DE69614564T patent/DE69614564T2/de not_active Expired - Lifetime
- 1996-12-02 GB GB9811570A patent/GB2321859B/en not_active Expired - Fee Related
- 1996-12-02 ES ES96940098T patent/ES2162117T3/es not_active Expired - Lifetime
- 1996-12-02 AU AU77070/96A patent/AU7707096A/en not_active Abandoned
- 1996-12-02 AT AT96940098T patent/ATE204193T1/de active
-
1998
- 1998-05-28 NO NO19982449A patent/NO315186B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO315186B1 (no) | 2003-07-28 |
| NO982449D0 (no) | 1998-05-28 |
| DE69614564D1 (de) | 2001-09-20 |
| ES2162117T3 (es) | 2001-12-16 |
| AU7707096A (en) | 1997-06-27 |
| EP0863782B1 (de) | 2001-08-16 |
| GB2321859B (en) | 2000-06-21 |
| NO982449L (no) | 1998-07-30 |
| GB9811570D0 (en) | 1998-07-29 |
| WO1997020609A1 (en) | 1997-06-12 |
| GB2321859A (en) | 1998-08-12 |
| EP0863782A1 (de) | 1998-09-16 |
| DE69614564T2 (de) | 2002-09-05 |
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