ATE204293T1 - Merkaptoalkanoyldipeptide derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusmmensetzungen - Google Patents

Merkaptoalkanoyldipeptide derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusmmensetzungen

Info

Publication number
ATE204293T1
ATE204293T1 AT96400136T AT96400136T ATE204293T1 AT E204293 T1 ATE204293 T1 AT E204293T1 AT 96400136 T AT96400136 T AT 96400136T AT 96400136 T AT96400136 T AT 96400136T AT E204293 T1 ATE204293 T1 AT E204293T1
Authority
AT
Austria
Prior art keywords
alkyl
mercapto
alkanoyl
production
pharmaceutical compositions
Prior art date
Application number
AT96400136T
Other languages
English (en)
Inventor
Bernard P Roques
Marie-Claude Fournie-Zaluski
Original Assignee
Adir
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir, Inst Nat Sante Rech Med filed Critical Adir
Application granted granted Critical
Publication of ATE204293T1 publication Critical patent/ATE204293T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT96400136T 1995-01-23 1996-01-22 Merkaptoalkanoyldipeptide derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusmmensetzungen ATE204293T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9500694A FR2729668A1 (fr) 1995-01-23 1995-01-23 Nouveaux derives de mercaptoalcanoyldipeptides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ATE204293T1 true ATE204293T1 (de) 2001-09-15

Family

ID=9475379

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96400136T ATE204293T1 (de) 1995-01-23 1996-01-22 Merkaptoalkanoyldipeptide derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusmmensetzungen

Country Status (17)

Country Link
US (1) US5741781A (de)
EP (1) EP0723974B1 (de)
JP (1) JPH08325290A (de)
CN (1) CN1137040A (de)
AT (1) ATE204293T1 (de)
AU (1) AU699204B2 (de)
CA (1) CA2167763A1 (de)
DE (1) DE69614417T2 (de)
DK (1) DK0723974T3 (de)
ES (1) ES2162986T3 (de)
FI (1) FI960284L (de)
FR (1) FR2729668A1 (de)
GR (1) GR3037041T3 (de)
NO (1) NO960250L (de)
NZ (1) NZ280870A (de)
PT (1) PT723974E (de)
ZA (1) ZA96516B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2729668A1 (fr) * 1995-01-23 1996-07-26 Adir Nouveaux derives de mercaptoalcanoyldipeptides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE19512484A1 (de) 1995-04-04 1996-10-17 Bayer Ag Kohlenhydratmodifizierte Cytostatika
RU2245147C2 (ru) * 1999-03-29 2005-01-27 Бристол-Маерс Сквибб Компани Применение ингибитора вазопептидазы для лечения стенокардии
FR2823212B1 (fr) * 2001-04-10 2005-12-02 Inst Nat Sante Rech Med Inhibiteurs de la toxine botulique de type b
FR2931151A1 (fr) * 2008-05-13 2009-11-20 Pharmaleads Soc Par Actions Si Nouveaux derives d'amino-acides, leur procede de preparation et leur utilisation therapeutique
SG176009A1 (en) * 2009-05-28 2011-12-29 Novartis Ag Substituted aminopropionic derivatives as neprilysin inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3272505D1 (en) * 1981-03-09 1986-09-18 Merck & Co Inc Substituted thiazolidine carboxylic acid analogs and derivatives as antihypertensives
US4560506A (en) * 1984-05-25 1985-12-24 E. R. Squibb & Sons, Inc. Mercaptocycloalkylcarbonyl and mercaptoarylcarbonyl dipeptides
FR2679564A1 (fr) * 1991-07-23 1993-01-29 Inst Nat Sante Rech Med Nouveaux acylmercaptoalcanoldipeptides, leur preparation et les compositions qui les contiennent.
WO1994017036A1 (en) * 1993-01-22 1994-08-04 Institut National De La Sante Et De La Recherche Medicale (Inserm) S-lipophilic aliphatic carbonyl [n-mercaptoacyl-(amino acid or peptide)] compounds as antihypertensive agents
FR2729668A1 (fr) * 1995-01-23 1996-07-26 Adir Nouveaux derives de mercaptoalcanoyldipeptides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
ZA96516B (en) 1996-08-15
AU699204B2 (en) 1998-11-26
ES2162986T3 (es) 2002-01-16
NO960250L (no) 1996-07-24
GR3037041T3 (en) 2002-01-31
EP0723974A1 (de) 1996-07-31
US5741781A (en) 1998-04-21
NO960250D0 (no) 1996-01-22
DE69614417T2 (de) 2002-05-29
FR2729668A1 (fr) 1996-07-26
AU4210196A (en) 1996-08-01
CA2167763A1 (fr) 1996-07-24
FI960284A7 (fi) 1996-07-24
DE69614417D1 (de) 2001-09-20
CN1137040A (zh) 1996-12-04
FI960284L (fi) 1996-07-24
DK0723974T3 (da) 2001-10-08
JPH08325290A (ja) 1996-12-10
EP0723974B1 (de) 2001-08-16
PT723974E (pt) 2001-11-30
NZ280870A (en) 1997-09-22
FR2729668B1 (de) 1997-02-21
FI960284A0 (fi) 1996-01-19

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