ATE205198T1 - N-(4-acetyl-1-piperazinyl)-4-fluorobenzamidhydr t - Google Patents
N-(4-acetyl-1-piperazinyl)-4-fluorobenzamidhydr tInfo
- Publication number
- ATE205198T1 ATE205198T1 AT97946110T AT97946110T ATE205198T1 AT E205198 T1 ATE205198 T1 AT E205198T1 AT 97946110 T AT97946110 T AT 97946110T AT 97946110 T AT97946110 T AT 97946110T AT E205198 T1 ATE205198 T1 AT E205198T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- piperazinyl
- acetyl
- date jun
- sec
- Prior art date
Links
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000000044 Amnesia Diseases 0.000 abstract 1
- 208000031091 Amnestic disease Diseases 0.000 abstract 1
- 206010039966 Senile dementia Diseases 0.000 abstract 1
- 230000006986 amnesia Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- XTOKQKWTUYYVAO-UHFFFAOYSA-N n-(4-acetylpiperazin-1-yl)-4-fluorobenzamide Chemical compound C1CN(C(=O)C)CCN1NC(=O)C1=CC=C(F)C=C1 XTOKQKWTUYYVAO-UHFFFAOYSA-N 0.000 abstract 1
- YCRCWHFFTTVANS-UHFFFAOYSA-N n-(4-acetylpiperazin-1-yl)-4-fluorobenzamide;hydrate Chemical compound O.C1CN(C(=O)C)CCN1NC(=O)C1=CC=C(F)C=C1 YCRCWHFFTTVANS-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/28—Nitrogen atoms
- C07D295/32—Nitrogen atoms acylated with carboxylic or carbonic acids, or their nitrogen or sulfur analogues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP33178496 | 1996-12-12 | ||
| PCT/JP1997/004451 WO1998025914A1 (en) | 1996-12-12 | 1997-12-05 | N-(4-acetyl-1-piperazinyl)-4-fluorobenzamide hydrate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE205198T1 true ATE205198T1 (de) | 2001-09-15 |
Family
ID=18247607
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97946110T ATE205198T1 (de) | 1996-12-12 | 1997-12-05 | N-(4-acetyl-1-piperazinyl)-4-fluorobenzamidhydr t |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6147079A (de) |
| EP (1) | EP0944612B1 (de) |
| JP (1) | JP3254683B2 (de) |
| KR (1) | KR20000057342A (de) |
| CN (1) | CN1073104C (de) |
| AT (1) | ATE205198T1 (de) |
| AU (1) | AU722095B2 (de) |
| CA (1) | CA2274682A1 (de) |
| DE (1) | DE69706562T2 (de) |
| DK (1) | DK0944612T3 (de) |
| EA (1) | EA001715B1 (de) |
| ES (1) | ES2160371T3 (de) |
| GR (1) | GR3036542T3 (de) |
| HU (1) | HUP0002975A3 (de) |
| IL (1) | IL130273A (de) |
| PT (1) | PT944612E (de) |
| TW (1) | TW422844B (de) |
| WO (1) | WO1998025914A1 (de) |
| ZA (1) | ZA9710872B (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010030637A (ko) * | 1997-10-09 | 2001-04-16 | 후지야마 아키라 | 아미노피페라진 유도체의 신규한 제조방법 |
| AUPP818099A0 (en) | 1999-01-14 | 1999-02-11 | Fujisawa Pharmaceutical Co., Ltd. | New n-containing heterocyclic compounds |
| US6344358B1 (en) * | 1999-05-28 | 2002-02-05 | Fujisawa Pharmaceutical Co., Ltd. | Agent for expression of long-term potentiation of synaptic transmission comprising compound having brain somatostatin activation property |
| GB0021885D0 (en) * | 2000-09-06 | 2000-10-18 | Fujisawa Pharmaceutical Co | New use |
| WO2002034735A1 (fr) * | 2000-10-23 | 2002-05-02 | Fujisawa Pharmaceutical Co., Ltd. | Procede de preparation d'un solvate et solvate |
| AU2002224046A1 (en) * | 2000-12-07 | 2002-06-18 | Fujisawa Pharmaceutical Co. Ltd. | Nootropic effect enhancer |
| US20060069104A1 (en) * | 2002-04-10 | 2006-03-30 | Toshio Matsuda | Neurotrophic factor production accelerator |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8917687D0 (en) * | 1989-08-02 | 1989-09-20 | Fujisawa Pharmaceutical Co | Aminopiperazine derivatives,processes for preparation thereof and pharmaceutical composition comprising the same |
| US5250528A (en) * | 1989-08-02 | 1993-10-05 | Fujisawa Pharmaceutical Co., Ltd. | New aminopiperazine derivatives |
-
1997
- 1997-12-03 ZA ZA9710872A patent/ZA9710872B/xx unknown
- 1997-12-05 IL IL13027397A patent/IL130273A/xx not_active IP Right Cessation
- 1997-12-05 DE DE69706562T patent/DE69706562T2/de not_active Expired - Fee Related
- 1997-12-05 PT PT97946110T patent/PT944612E/pt unknown
- 1997-12-05 HU HU0002975A patent/HUP0002975A3/hu unknown
- 1997-12-05 WO PCT/JP1997/004451 patent/WO1998025914A1/en not_active Ceased
- 1997-12-05 US US09/319,271 patent/US6147079A/en not_active Expired - Fee Related
- 1997-12-05 JP JP50681698A patent/JP3254683B2/ja not_active Expired - Fee Related
- 1997-12-05 EP EP97946110A patent/EP0944612B1/de not_active Expired - Lifetime
- 1997-12-05 KR KR1019990704843A patent/KR20000057342A/ko not_active Ceased
- 1997-12-05 DK DK97946110T patent/DK0944612T3/da active
- 1997-12-05 ES ES97946110T patent/ES2160371T3/es not_active Expired - Lifetime
- 1997-12-05 EA EA199900530A patent/EA001715B1/ru not_active IP Right Cessation
- 1997-12-05 CN CN97181731A patent/CN1073104C/zh not_active Expired - Fee Related
- 1997-12-05 AT AT97946110T patent/ATE205198T1/de not_active IP Right Cessation
- 1997-12-05 CA CA002274682A patent/CA2274682A1/en not_active Abandoned
- 1997-12-05 AU AU51368/98A patent/AU722095B2/en not_active Ceased
- 1997-12-11 TW TW086118669A patent/TW422844B/zh not_active IP Right Cessation
-
2001
- 2001-09-06 GR GR20010401324T patent/GR3036542T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2160371T3 (es) | 2001-11-01 |
| EA001715B1 (ru) | 2001-08-27 |
| JP2000514460A (ja) | 2000-10-31 |
| JP3254683B2 (ja) | 2002-02-12 |
| HUP0002975A3 (en) | 2002-01-28 |
| AU722095B2 (en) | 2000-07-20 |
| US6147079A (en) | 2000-11-14 |
| EP0944612B1 (de) | 2001-09-05 |
| EP0944612A1 (de) | 1999-09-29 |
| WO1998025914A1 (en) | 1998-06-18 |
| PT944612E (pt) | 2002-01-30 |
| AU5136898A (en) | 1998-07-03 |
| CN1073104C (zh) | 2001-10-17 |
| IL130273A0 (en) | 2000-06-01 |
| DK0944612T3 (da) | 2001-11-19 |
| CN1245495A (zh) | 2000-02-23 |
| GR3036542T3 (en) | 2001-12-31 |
| IL130273A (en) | 2003-05-29 |
| EA199900530A1 (ru) | 1999-12-29 |
| ZA9710872B (en) | 1998-06-15 |
| DE69706562T2 (de) | 2002-05-29 |
| DE69706562D1 (de) | 2001-10-11 |
| TW422844B (en) | 2001-02-21 |
| CA2274682A1 (en) | 1998-06-18 |
| HK1024482A1 (en) | 2000-10-13 |
| KR20000057342A (ko) | 2000-09-15 |
| HUP0002975A2 (hu) | 2001-12-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |