ATE205669T1 - Verfahren zum präparieren von gewebe für die transplantation - Google Patents

Verfahren zum präparieren von gewebe für die transplantation

Info

Publication number
ATE205669T1
ATE205669T1 AT92911147T AT92911147T ATE205669T1 AT E205669 T1 ATE205669 T1 AT E205669T1 AT 92911147 T AT92911147 T AT 92911147T AT 92911147 T AT92911147 T AT 92911147T AT E205669 T1 ATE205669 T1 AT E205669T1
Authority
AT
Austria
Prior art keywords
tissue
cells
transplantation
cryoprotectant
dilution step
Prior art date
Application number
AT92911147T
Other languages
English (en)
Inventor
John F Carpenter
Kelvin G M Brockbank
Original Assignee
Cryolife Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cryolife Inc filed Critical Cryolife Inc
Application granted granted Critical
Publication of ATE205669T1 publication Critical patent/ATE205669T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/16—Physical preservation processes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/27—Cryogenic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/901—Method of manufacturing prosthetic device

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Compounds Of Unknown Constitution (AREA)
AT92911147T 1991-05-14 1992-05-14 Verfahren zum präparieren von gewebe für die transplantation ATE205669T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/699,873 US5160313A (en) 1991-05-14 1991-05-14 Process for preparing tissue for transplantation
PCT/US1992/004065 WO1992020300A1 (en) 1991-05-14 1992-05-14 Process for preparing tissue for transplant

Publications (1)

Publication Number Publication Date
ATE205669T1 true ATE205669T1 (de) 2001-10-15

Family

ID=24811272

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92911147T ATE205669T1 (de) 1991-05-14 1992-05-14 Verfahren zum präparieren von gewebe für die transplantation

Country Status (9)

Country Link
US (1) US5160313A (de)
EP (1) EP0584195B1 (de)
AT (1) ATE205669T1 (de)
AU (1) AU1891892A (de)
CA (1) CA2103025C (de)
DE (1) DE69232065T2 (de)
DK (1) DK0584195T3 (de)
ES (1) ES2164051T3 (de)
WO (1) WO1992020300A1 (de)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5336616A (en) * 1990-09-12 1994-08-09 Lifecell Corporation Method for processing and preserving collagen-based tissues for transplantation
US8067149B2 (en) 1990-09-12 2011-11-29 Lifecell Corporation Acellular dermal matrix and method of use thereof for grafting
US5723282A (en) 1991-07-08 1998-03-03 The American National Red Cross Method of preparing organs for vitrification
IT1256621B (it) * 1992-12-04 1995-12-12 Soluzioni crioprotettrici
US5833685A (en) * 1994-03-15 1998-11-10 Tortal; Proserfina R. Cryosurgical technique and devices
US5984858A (en) * 1995-06-07 1999-11-16 Crosscart, Inc. Meniscal xenografts
US6046379A (en) * 1995-06-07 2000-04-04 Stone; Kevin R. Meniscal xenografts
US5741248A (en) * 1995-06-07 1998-04-21 Temple University-Of The Commonwealth System Of Higher Education Fluorochemical liquid augmented cryosurgery
US6231608B1 (en) 1995-06-07 2001-05-15 Crosscart, Inc. Aldehyde and glycosidase-treated soft and bone tissue xenografts
US5865849A (en) * 1995-06-07 1999-02-02 Crosscart, Inc. Meniscal heterografts
US5913900A (en) * 1995-06-07 1999-06-22 Corsscart, Inc. Substantially native meniscal cartilage heterografts
US5702444A (en) * 1995-09-11 1997-12-30 Struthers, Mehta And Maxwell Implantable artificial endocrine pancreas
US5944755A (en) * 1995-09-15 1999-08-31 Crosscart, Inc. Articular cartilage xenografts
US5902338A (en) * 1995-09-15 1999-05-11 Crosscart, Inc. Anterior cruciate ligament heterograft
US6049025A (en) * 1995-09-15 2000-04-11 Stone; Kevin R. Articular cartilage xenografts
US5782915A (en) * 1995-09-15 1998-07-21 Stone; Kevin R. Articular cartilage heterografts
US6110206A (en) * 1995-09-15 2000-08-29 Crosscart, Inc. Anterior cruciate ligament xenografts
US6210440B1 (en) 1995-09-15 2001-04-03 Kevin R. Stone Anterior cruciate ligament xenografts
US5962213A (en) * 1996-06-14 1999-10-05 Biostore New Zealand Limited Compositions and methods for the preservation of living tissues
US5879875A (en) * 1996-06-14 1999-03-09 Biostore New Zealand Compositions and methods for the preservation of living tissues
US6114107A (en) * 1996-06-14 2000-09-05 Biostore New Zealand Limited Composition comprising raffinose, TMAO, sodium citrate and methods for the preservation of living tissues
US6743575B2 (en) 1996-06-14 2004-06-01 Biostore New Zealand Ltd. Compositions and methods for the preservation of living tissues
US6037116A (en) * 1996-06-14 2000-03-14 Biostore New Zealand, Ltd. Compositions comprising betaine, sodium citrate and sodium chloride and methods for the preservation of biological materials
US6361933B1 (en) 1996-06-14 2002-03-26 Biostore New Zealand Limited Solutions for the preservation of tissues
AU4252097A (en) * 1996-09-06 1998-03-26 Universal Preservation Technologies, Inc. Vitrification solutions for shelf preservation of cells, tissues, organs and organisms
EP1059891A4 (de) 1998-03-06 2004-05-19 Crosscart Inc Xenotransplantate aus weichem gewebe
US6383732B1 (en) 1999-02-11 2002-05-07 Crosscart, Inc. Method of preparing xenograft heart valves
WO1999047080A1 (en) 1998-03-16 1999-09-23 Crosscart, Inc. Bone xenografts
US6972041B1 (en) 1998-03-16 2005-12-06 Crosscart, Inc. Bone xenografts
US6933326B1 (en) 1998-06-19 2005-08-23 Lifecell Coporation Particulate acellular tissue matrix
US6140123A (en) * 1998-10-07 2000-10-31 Cedars-Sinai Medical Center Method for conditioning and cryopreserving cells
US6267786B1 (en) 1999-02-11 2001-07-31 Crosscart, Inc. Proteoglycan-reduced soft tissue xenografts
WO2001028604A1 (en) * 1999-10-15 2001-04-26 The Brigham And Women's Hospital, Inc. Fresh, cryopreserved, or minimally fixed cardiac valvular xenografts
AU2002246747A1 (en) 2000-12-27 2002-08-06 Ortec International, Inc. Processes for making cryopreserved composite living constructs and products resulting therefrom
JP2004529711A (ja) * 2001-05-07 2004-09-30 クロスカート インコーポレイテッド 粘膜下異種移植片
US7064187B2 (en) 2002-11-26 2006-06-20 Crosscart, Inc. Substantially non-immunogenic injectable collagen
US20080306610A1 (en) * 2007-06-07 2008-12-11 Zimmer Orthobiologics, Inc. Tissue processing for nonimmunogenic implants
US20090181807A1 (en) * 2008-01-16 2009-07-16 Jason Miguel De Los Santos Golfing aid
US8469779B1 (en) 2009-01-02 2013-06-25 Lifecell Corporation Method for debristling animal skin
WO2010105021A2 (en) * 2009-03-11 2010-09-16 Cryolife, Inc. Bioburden-reducing antibiotic composition and method of use
US8475827B2 (en) 2010-07-06 2013-07-02 Cryolife, Inc. Tissue implants for implantation and methods for preparing the same
US8377143B2 (en) 2010-07-06 2013-02-19 Cryolife, Inc. Tissue implants for implantation and methods for preparing the same
US8435305B2 (en) 2010-08-31 2013-05-07 Zimmer, Inc. Osteochondral graft delivery device and uses thereof
BR112013026200A2 (pt) 2011-04-14 2019-08-27 Lifecell Corp método para preparar uma composição de matriz de tecido, e matriz de tecido
US9089523B2 (en) 2011-07-28 2015-07-28 Lifecell Corporation Natural tissue scaffolds as tissue fillers
US9532863B2 (en) 2011-12-20 2017-01-03 Lifecell Corporation Sheet tissue products
CA2859657C (en) 2011-12-20 2021-03-02 Lifecell Corporation Acellular tissue matrix particles and flowable products comprising them
CA2861048C (en) 2012-01-24 2021-01-12 Lifecell Corporation Elongated tissue matrices
BR112014026090A8 (pt) 2012-04-24 2019-08-27 Lifecell Corp composição de matriz tecidual apta a fluir
ES2753156T3 (es) 2012-07-13 2020-04-07 Lifecell Corp Procedimientos de tratamiento mejorado de tejido adiposo
EP3332816B1 (de) 2012-09-26 2020-11-04 LifeCell Corporation Verarbeitetes fettgewebe
CN108042849B (zh) 2013-02-06 2021-04-20 生命细胞公司 用于组织产物的局部改性的方法
WO2016154452A2 (en) 2015-03-24 2016-09-29 Osiris Therapeutics, Inc. Compositions comprising meniscal tissues and uses thereof
WO2017210109A1 (en) 2016-06-03 2017-12-07 Lifecell Corporation Methods for localized modification of tissue products
AU2017382173A1 (en) 2016-12-22 2019-06-06 Lifecell Corporation Devices and methods for tissue cryomilling
JP7297739B2 (ja) 2017-10-18 2023-06-26 ライフセル コーポレーション 脂肪組織製品および製造方法
US11123375B2 (en) 2017-10-18 2021-09-21 Lifecell Corporation Methods of treating tissue voids following removal of implantable infusion ports using adipose tissue products
US11246994B2 (en) 2017-10-19 2022-02-15 Lifecell Corporation Methods for introduction of flowable acellular tissue matrix products into a hand
JP7463273B2 (ja) 2017-10-19 2024-04-08 ライフセル コーポレーション 流動性無細胞組織マトリックス製品および製造方法
EP3976127B1 (de) 2019-05-30 2025-09-24 LifeCell Corporation Biologisches brustimplantat
CN117427219A (zh) * 2023-10-24 2024-01-23 中国医学科学院阜外医院 脱细胞带瓣管道制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3303662A (en) * 1963-03-01 1967-02-14 Union Carbide Corp Process for cell preservation
US4380997A (en) * 1981-04-07 1983-04-26 Rio Vista International, Inc. Embryo transfer method and apparatus
US4423600A (en) * 1982-12-10 1984-01-03 Mckenna Joan J Method for preservation of living organic tissue by freezing
US4890457A (en) * 1987-01-02 1990-01-02 Cryolife, Inc. Method for cryopreserving heart valves
US5145769A (en) * 1987-08-21 1992-09-08 Cryolife Inc. Method for cryopreserving blood vessels
US5145770A (en) * 1990-06-04 1992-09-08 Biosurface Technology, Inc. Cryopreservation of cultured epithelial sheets

Also Published As

Publication number Publication date
EP0584195A4 (de) 1994-08-03
CA2103025C (en) 2002-10-01
US5160313A (en) 1992-11-03
EP0584195B1 (de) 2001-09-19
AU1891892A (en) 1992-12-30
ES2164051T3 (es) 2002-02-16
DE69232065D1 (de) 2001-10-25
EP0584195A1 (de) 1994-03-02
CA2103025A1 (en) 1992-11-15
DE69232065T2 (de) 2002-01-31
DK0584195T3 (da) 2001-11-12
WO1992020300A1 (en) 1992-11-26

Similar Documents

Publication Publication Date Title
DE69232065D1 (de) Verfahren zum präparieren von gewebe für die transplantation
PT719084E (pt) Criopreservacao de equivalentes de tecidos cultivados
EP0564786A3 (en) Method for processing and preserving collagen-based tissues for transplantation
DE69530212D1 (de) Verfahren zur vorbereitung von organen auf die kryokonservierung
US5827511A (en) Preservative and embalming fluid
MY106588A (en) Improvements in or relating to fungicides.
TR199701012T1 (xx) Fungisidal kompozisyon.
WO1991007967A3 (en) Method of preventing or limiting reperfusion damage
US5622695A (en) Anatomical and biological preservative and method
ES8707720A1 (es) Procedimiento para preparar derivados azolilalquilicos
US6601275B2 (en) Method and composition for embalming
Sherman Pretreatment with protective substances as a factor in freeze-thaw survival
DK156686C (da) Fremgangsmaade og konserveringsvaeske til konservering af planter
Kopcewicz et al. Estrogens in 2-chloroethylphosphonic acid induced femaleness of Cucurbita pepo L.
EA199801074A1 (ru) Гербицидный состав и способ борьбы с нежелательными растениями
JPS5576814A (en) Preservative solution for organ transplant
DE3773206D1 (de) Verfahren zur gewinnung von beta-aescinreichen extrakten.
ES2113326A1 (es) Procedimiento de conservacion de patata pelada fresca.
Ochotorena Continued Preservation of Salt-Embalmed Cats
UA13687A1 (uk) Спосіб коhсервуваhhя гемопоетичhих клітиh ембріоhальhої печіhки людиhи
di San Secondo Dimethylsulfoxide as a polyclonal B-cell activator
Pollock et al. Arterial cryopreservation: Methods of assessing endothelial damage
Schmid Low temperature survival of terrestrial frogs
ES2003338A6 (es) Procedimiento para la preparacion de sustancias protectoras y reguladoras del crecimiento de plantas de cultivo
GB338011A (en) Improvements in and relating to processes for preserving materials of animal origin

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee