ATE206467T1 - 'terminal repeat'- amplifikation - Google Patents

'terminal repeat'- amplifikation

Info

Publication number
ATE206467T1
ATE206467T1 AT95940256T AT95940256T ATE206467T1 AT E206467 T1 ATE206467 T1 AT E206467T1 AT 95940256 T AT95940256 T AT 95940256T AT 95940256 T AT95940256 T AT 95940256T AT E206467 T1 ATE206467 T1 AT E206467T1
Authority
AT
Austria
Prior art keywords
rna
dna
template
sequence
promoter
Prior art date
Application number
AT95940256T
Other languages
English (en)
Inventor
Roy Sooknanan
Lawrence Malek
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of ATE206467T1 publication Critical patent/ATE206467T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Electrotherapy Devices (AREA)
  • Channel Selection Circuits, Automatic Tuning Circuits (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
  • Amplifiers (AREA)
  • Seal Device For Vehicle (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
AT95940256T 1994-11-28 1995-11-28 'terminal repeat'- amplifikation ATE206467T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/345,505 US5665545A (en) 1994-11-28 1994-11-28 Terminal repeat amplification method
PCT/EP1995/004694 WO1996017079A1 (en) 1994-11-28 1995-11-28 Terminal repeat amplification method

Publications (1)

Publication Number Publication Date
ATE206467T1 true ATE206467T1 (de) 2001-10-15

Family

ID=23355318

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95940256T ATE206467T1 (de) 1994-11-28 1995-11-28 'terminal repeat'- amplifikation

Country Status (10)

Country Link
US (1) US5665545A (de)
EP (1) EP0796343B1 (de)
JP (1) JP3745774B2 (de)
AT (1) ATE206467T1 (de)
AU (1) AU711589B2 (de)
CA (1) CA2205563A1 (de)
DE (1) DE69523068T2 (de)
ES (1) ES2168112T3 (de)
FI (1) FI972238A7 (de)
WO (1) WO1996017079A1 (de)

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US6864050B2 (en) * 1999-07-30 2005-03-08 Affymetrix, Inc. Single-phase amplification of nucleic acids
ATE262595T1 (de) * 1999-09-13 2004-04-15 Nugen Technologies Inc Methoden und zusammensetzungen zur linearen isothermalen amplifikation von polynukleotidsequenzen
US6692918B2 (en) 1999-09-13 2004-02-17 Nugen Technologies, Inc. Methods and compositions for linear isothermal amplification of polynucleotide sequences
EP1356094B1 (de) * 2000-06-26 2010-01-13 Nugen Technologies, Inc. Methoden und zusammensetzungen zur auf transkription basierenden vervielfältigung von nukleinsäuren
US7846733B2 (en) 2000-06-26 2010-12-07 Nugen Technologies, Inc. Methods and compositions for transcription-based nucleic acid amplification
EP1427847B1 (de) 2000-12-13 2010-07-28 Nugen Technologies, Inc. Methoden und zusammensetzungen zur generierung einer vielzahl von kopien von nukleinsäuresequenzen und methoden zur detektion derselben
MXPA02012739A (es) 2001-03-09 2004-04-20 Nugen Technologies Inc Metodos y composiciones para amplificacion de secuencias de arn.
EP1390537B1 (de) * 2001-03-09 2013-11-13 Nugen Technologies, Inc. Verfahren und zusammensetzungen zur amplifikation von rna-sequenzen
AU2003303395A1 (en) * 2001-05-22 2004-07-22 Dahl, Gary, A. Target-dependent transcription using deletion mutants of n4 rna polymerase
US8137911B2 (en) * 2001-05-22 2012-03-20 Cellscript, Inc. Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
WO2003020979A1 (en) * 2001-08-31 2003-03-13 Rosetta Inpharmactis Llc. Methods for preparing nucleic acid samples
WO2003078645A2 (en) * 2002-03-11 2003-09-25 Nugen Technologies, Inc. Methods for generating double stranded dna comprising a 3’ single stranded portion and uses of these complexes for recombination
SE0202867D0 (sv) * 2002-09-27 2002-09-27 Pyrosequencing Ab New sequencing method
AU2003297557B2 (en) 2002-11-21 2009-02-26 Cellscript, Inc. Methods for using primers that encode one strand of a double-stranded promoter
JP2006523465A (ja) * 2003-04-14 2006-10-19 ニューゲン テクノロジーズ, インコーポレイテッド ランダムにプライミングされる複合プライマーを用いる大規模増幅
WO2006034387A1 (en) * 2004-09-21 2006-03-30 Applera Corporation TWO-COLOR REAL-TIME/END-POINT QUANTITATION OF MICRORNAS (miRNAs)
US7579153B2 (en) * 2005-01-25 2009-08-25 Population Genetics Technologies, Ltd. Isothermal DNA amplification
EP1929046B1 (de) 2005-09-07 2012-07-11 Nugen Technologies, Inc. Verbessertes nukleinsäureamplifikationsverfahren
US7501254B2 (en) 2006-07-20 2009-03-10 Ghc Technologies, Inc. Methods and compositions for amplification and capture of nucleic acid sequences
US8039214B2 (en) * 2007-06-29 2011-10-18 Cellscript, Inc. Synthesis of tagged nucleic acids
US8034568B2 (en) 2008-02-12 2011-10-11 Nugen Technologies, Inc. Isothermal nucleic acid amplification methods and compositions
US7846666B2 (en) 2008-03-21 2010-12-07 Nugen Technologies, Inc. Methods of RNA amplification in the presence of DNA
JP5481841B2 (ja) * 2008-11-28 2014-04-23 東ソー株式会社 サイトケラチン19mRNAの測定方法
CA2807552A1 (en) 2010-08-06 2012-02-09 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
EP2857499A1 (de) 2010-10-01 2015-04-08 Moderna Therapeutics, Inc. Manipulierte Nukleinsäuren und Verfahren zur Verwendung davon
US20120196294A1 (en) 2011-01-17 2012-08-02 Life Technologies Corporation Workflow for detection of ligands using nucleic acids
CA2831613A1 (en) 2011-03-31 2012-10-04 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
PT3682905T (pt) 2011-10-03 2022-04-07 Modernatx Inc Nucleósidos, nucleótidos e ácidos nucleicos modificados e respetivas utilizações
ES2923757T3 (es) 2011-12-16 2022-09-30 Modernatx Inc Composiciones de ARNm modificado
WO2013151664A1 (en) 2012-04-02 2013-10-10 modeRNA Therapeutics Modified polynucleotides for the production of proteins
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US10501512B2 (en) 2012-04-02 2019-12-10 Modernatx, Inc. Modified polynucleotides
CN102943100B (zh) * 2012-11-23 2014-04-16 郑州安图生物工程股份有限公司 高效RNA逆转录合成cDNA的方法
PT2922554T (pt) 2012-11-26 2022-06-28 Modernatx Inc Arn modificado nas porções terminais
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
KR20160067219A (ko) 2013-10-03 2016-06-13 모더나 세라퓨틱스, 인코포레이티드 저밀도 지단백질 수용체를 암호화하는 폴리뉴클레오타이드
JP6560336B2 (ja) 2015-02-26 2019-08-14 株式会社日立ハイテクノロジーズ 核酸分子の構築方法
NL2022993B1 (en) * 2019-04-23 2020-11-02 Synvolux Ip Bv Methods and compositions for isothermal DNA amplification
WO2021007233A1 (en) * 2019-07-10 2021-01-14 The Board Of Trustees Of The Leland Stanford Junior University Rna replication using transcription polymerases

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Also Published As

Publication number Publication date
JP3745774B2 (ja) 2006-02-15
FI972238A0 (fi) 1997-05-27
AU711589B2 (en) 1999-10-14
FI972238A7 (fi) 1997-05-27
JPH10510161A (ja) 1998-10-06
EP0796343B1 (de) 2001-10-04
WO1996017079A1 (en) 1996-06-06
AU4176796A (en) 1996-06-19
US5665545A (en) 1997-09-09
EP0796343A1 (de) 1997-09-24
DE69523068D1 (en) 2001-11-08
CA2205563A1 (en) 1996-06-06
DE69523068T2 (de) 2002-06-06
ES2168112T3 (es) 2002-06-01

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