ATE206467T1 - 'terminal repeat'- amplifikation - Google Patents

'terminal repeat'- amplifikation

Info

Publication number: ATE206467T1
Authority: AT; Austria
Prior art keywords: rna; dna; template; sequence; promoter
Prior art date: 1994-11-28

Application number

AT95940256T

Other languages

English (en)

Inventor

Roy Sooknanan

Lawrence Malek

Original Assignee

Akzo Nobel Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-11-28

Filing date

1995-11-28

Publication date

2001-10-15

1995-11-28 Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv

2001-10-15 Application granted granted Critical

2001-10-15 Publication of ATE206467T1 publication Critical patent/ATE206467T1/de

Links

230000003321 amplification Effects 0.000 title abstract 2
238000003199 nucleic acid amplification method Methods 0.000 title abstract 2
108091032973 (ribonucleotides)n+m Proteins 0.000 abstract 8
108020004414 DNA Proteins 0.000 abstract 8
230000000295 complement effect Effects 0.000 abstract 5
230000000977 initiatory effect Effects 0.000 abstract 5
238000000034 method Methods 0.000 abstract 4
102000016928 DNA-directed DNA polymerase Human genes 0.000 abstract 3
108010014303 DNA-directed DNA polymerase Proteins 0.000 abstract 3
102000004163 DNA-directed RNA polymerases Human genes 0.000 abstract 3
108090000626 DNA-directed RNA polymerases Proteins 0.000 abstract 3
108091028043 Nucleic acid sequence Proteins 0.000 abstract 3
150000007523 nucleic acids Chemical group 0.000 abstract 3
230000037452 priming Effects 0.000 abstract 3
102000053602 DNA Human genes 0.000 abstract 2
102000006382 Ribonucleases Human genes 0.000 abstract 2
108010083644 Ribonucleases Proteins 0.000 abstract 2
239000003153 chemical reaction reagent Substances 0.000 abstract 2
239000012429 reaction media Substances 0.000 abstract 2
102000040650 (ribonucleotides)n+m Human genes 0.000 abstract 1
NYHBQMYGNKIUIF-UUOKFMHZSA-N Guanosine Chemical compound C1=NC=2C(=O)NC(N)=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O NYHBQMYGNKIUIF-UUOKFMHZSA-N 0.000 abstract 1
239000005549 deoxyribonucleoside Substances 0.000 abstract 1
230000003301 hydrolyzing effect Effects 0.000 abstract 1
239000002342 ribonucleoside Substances 0.000 abstract 1
239000001226 triphosphate Substances 0.000 abstract 1
235000011178 triphosphate Nutrition 0.000 abstract 1
125000002264 triphosphate group Chemical class [H]OP(=O)(O[H])OP(=O)(O[H])OP(=O)(O[H])O* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Wood Science & Technology (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Physics & Mathematics (AREA)
Chemical Kinetics & Catalysis (AREA)
Biophysics (AREA)
Analytical Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Oscillators With Electromechanical Resonators (AREA)
Amplifiers (AREA)
Steroid Compounds (AREA)
Channel Selection Circuits, Automatic Tuning Circuits (AREA)
Electrotherapy Devices (AREA)
Seal Device For Vehicle (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Peptides Or Proteins (AREA)

AT95940256T 1994-11-28 1995-11-28 'terminal repeat'- amplifikation ATE206467T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/345,505 US5665545A (en)	1994-11-28	1994-11-28	Terminal repeat amplification method
PCT/EP1995/004694 WO1996017079A1 (en)	1994-11-28	1995-11-28	Terminal repeat amplification method

Publications (1)

Publication Number	Publication Date
ATE206467T1 true ATE206467T1 (de)	2001-10-15

Family

ID=23355318

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95940256T ATE206467T1 (de)	1994-11-28	1995-11-28	'terminal repeat'- amplifikation

Country Status (10)

Country	Link
US (1)	US5665545A (de)
EP (1)	EP0796343B1 (de)
JP (1)	JP3745774B2 (de)
AT (1)	ATE206467T1 (de)
AU (1)	AU711589B2 (de)
CA (1)	CA2205563A1 (de)
DE (1)	DE69523068T2 (de)
ES (1)	ES2168112T3 (de)
FI (1)	FI972238A0 (de)
WO (1)	WO1996017079A1 (de)

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US6251639B1 (en) *	1999-09-13	2001-06-26	Nugen Technologies, Inc.	Methods and compositions for linear isothermal amplification of polynucleotide sequences, using a RNA-DNA composite primer
US6692918B2 (en) *	1999-09-13	2004-02-17	Nugen Technologies, Inc.	Methods and compositions for linear isothermal amplification of polynucleotide sequences
JP2004513617A (ja) *	2000-06-26	2004-05-13	ニューゲン　テクノロジーズ，　インコーポレイテッド	転写に基づく核酸増幅のための方法および組成物
US7846733B2 (en)	2000-06-26	2010-12-07	Nugen Technologies, Inc.	Methods and compositions for transcription-based nucleic acid amplification
AU2002228974A1 (en)	2000-12-13	2002-06-24	Nugen Technologies, Inc	Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof
CA2439074A1 (en) *	2001-03-09	2002-09-19	Nugen Technologies, Inc.	Methods and compositions for amplification of rna sequences
US6946251B2 (en) *	2001-03-09	2005-09-20	Nugen Technologies, Inc.	Methods and compositions for amplification of RNA sequences using RNA-DNA composite primers
US8137911B2 (en) *	2001-05-22	2012-03-20	Cellscript, Inc.	Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
WO2004059289A2 (en) *	2001-05-22	2004-07-15	Epicentre Technologies	Target-dependent transcription using deletion mutants of n4 rna polymerase
AU2002322518A1 (en) *	2001-08-31	2003-03-18	Rosetta Inpharmactis Llc	Methods for preparing nucleic acid samples
US7176025B2 (en) *	2002-03-11	2007-02-13	Nugen Technologies, Inc.	Methods for generating double stranded DNA comprising a 3′ single stranded portion and uses of these complexes for recombination
SE0202867D0 (sv) *	2002-09-27	2002-09-27	Pyrosequencing Ab	New sequencing method
EP1576188B1 (de) *	2002-11-21	2008-10-15	Epicentre Technologies	Verfahren zur verwendung von riboprimern zur strangverdrängungsreplikation von zielsequenzen
WO2004092418A2 (en)	2003-04-14	2004-10-28	Nugen Technologies, Inc.	Global amplification using a randomly primed composite primer
US7642055B2 (en) *	2004-09-21	2010-01-05	Applied Biosystems, Llc	Two-color real-time/end-point quantitation of microRNAs (miRNAs)
EP1841879A4 (de) *	2005-01-25	2009-05-27	Population Genetics Technologi	Isothermische dna-amplifikation
EP1929046B1 (de)	2005-09-07	2012-07-11	Nugen Technologies, Inc.	Verbessertes nukleinsäureamplifikationsverfahren
US7501254B2 (en)	2006-07-20	2009-03-10	Ghc Technologies, Inc.	Methods and compositions for amplification and capture of nucleic acid sequences
CA2707436C (en) *	2007-06-29	2014-01-28	Epicentre Technologies Corporation	Copy dna and sense rna
US20090203531A1 (en)	2008-02-12	2009-08-13	Nurith Kurn	Method for Archiving and Clonal Expansion
WO2009117698A2 (en)	2008-03-21	2009-09-24	Nugen Technologies, Inc.	Methods of rna amplification in the presence of dna
JP5481841B2 (ja) *	2008-11-28	2014-04-23	東ソー株式会社	サイトケラチン１９ｍＲＮＡの測定方法
US8822663B2 (en)	2010-08-06	2014-09-02	Moderna Therapeutics, Inc.	Engineered nucleic acids and methods of use thereof
DK4108671T3 (da)	2010-10-01	2025-01-06	Modernatx Inc	Modificerede nukleosider, nukleotider og nukleinsyrer samt anvendelser deraf
EP3567121B1 (de)	2011-01-17	2023-08-30	Life Technologies Corporation	Arbeitsablauf zum nachweis von liganden mit nukleinsäuren
JP2014511687A (ja)	2011-03-31	2014-05-19	モデルナセラピューティクスインコーポレイテッド	工学操作された核酸の送達および製剤
US9464124B2 (en)	2011-09-12	2016-10-11	Moderna Therapeutics, Inc.	Engineered nucleic acids and methods of use thereof
JP6113737B2 (ja)	2011-10-03	2017-04-12	モデルナティエックスインコーポレイテッドＭｏｄｅｒｎａＴＸ，Ｉｎｃ．	修飾型のヌクレオシド、ヌクレオチドおよび核酸、ならびにそれらの使用方法
KR20140102759A (ko)	2011-12-16	2014-08-22	모더나 세라퓨틱스, 인코포레이티드	변형된 뉴클레오사이드, 뉴클레오타이드 및 핵산 조성물
US9572897B2 (en)	2012-04-02	2017-02-21	Modernatx, Inc.	Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9283287B2 (en)	2012-04-02	2016-03-15	Moderna Therapeutics, Inc.	Modified polynucleotides for the production of nuclear proteins
US9254311B2 (en)	2012-04-02	2016-02-09	Moderna Therapeutics, Inc.	Modified polynucleotides for the production of proteins
EP2834259A4 (de)	2012-04-02	2016-08-24	Moderna Therapeutics Inc	Modifizierte polynukleotide
CN102943100B (zh) *	2012-11-23	2014-04-16	郑州安图生物工程股份有限公司	高效RNA逆转录合成cDNA的方法
US9597380B2 (en)	2012-11-26	2017-03-21	Modernatx, Inc.	Terminally modified RNA
US8980864B2 (en)	2013-03-15	2015-03-17	Moderna Therapeutics, Inc.	Compositions and methods of altering cholesterol levels
EP3052521A1 (de)	2013-10-03	2016-08-10	Moderna Therapeutics, Inc.	Polynukleotide zur codierung von low-density-lipoprotein-rezeptor
DE112016000293T5 (de)	2015-02-26	2017-09-21	Hitachi High-Technologies Corporation	Verfahren zum konstruieren eines nucleinsäure-moleküls
NL2022993B1 (en) *	2019-04-23	2020-11-02	Synvolux Ip Bv	Methods and compositions for isothermal DNA amplification
WO2021007233A1 (en) *	2019-07-10	2021-01-14	The Board Of Trustees Of The Leland Stanford Junior University	Rna replication using transcription polymerases

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US4683195A (en) *	1986-01-30	1987-07-28	Cetus Corporation	Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) *	1985-03-28	1987-07-28	Cetus Corporation	Process for amplifying nucleic acid sequences
CA1340807C (en) *	1988-02-24	1999-11-02	Lawrence T. Malek	Nucleic acid amplification process
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1994
- 1994-11-28 US US08/345,505 patent/US5665545A/en not_active Expired - Fee Related
1995
- 1995-11-28 CA CA002205563A patent/CA2205563A1/en not_active Abandoned
- 1995-11-28 WO PCT/EP1995/004694 patent/WO1996017079A1/en not_active Ceased
- 1995-11-28 EP EP95940256A patent/EP0796343B1/de not_active Expired - Lifetime
- 1995-11-28 JP JP51818496A patent/JP3745774B2/ja not_active Expired - Fee Related
- 1995-11-28 DE DE69523068T patent/DE69523068T2/de not_active Expired - Fee Related
- 1995-11-28 AT AT95940256T patent/ATE206467T1/de not_active IP Right Cessation
- 1995-11-28 AU AU41767/96A patent/AU711589B2/en not_active Ceased
- 1995-11-28 ES ES95940256T patent/ES2168112T3/es not_active Expired - Lifetime
1997
- 1997-05-27 FI FI972238A patent/FI972238A0/fi unknown

Also Published As

Publication number	Publication date
WO1996017079A1 (en)	1996-06-06
US5665545A (en)	1997-09-09
AU711589B2 (en)	1999-10-14
FI972238A7 (fi)	1997-05-27
ES2168112T3 (es)	2002-06-01
EP0796343B1 (de)	2001-10-04
DE69523068T2 (de)	2002-06-06
JPH10510161A (ja)	1998-10-06
DE69523068D1 (en)	2001-11-08
CA2205563A1 (en)	1996-06-06
FI972238A0 (fi)	1997-05-27
AU4176796A (en)	1996-06-19
EP0796343A1 (de)	1997-09-24
JP3745774B2 (ja)	2006-02-15

Legal Events

Date	Code	Title	Description
2002-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69523068D1 (en)	2001-11-08	'terminal repeat'- amplifikation
US5916779A (en)	1999-06-29	Strand displacement amplification of RNA targets
EP1256630B1 (de)	2008-06-18	Selektive Polymerasekettenreaktion von DNA, deren Basensequenz vollständig unbekannt ist
JP3867926B2 (ja)	2007-01-17	核酸の増幅法
AU2006251866B2 (en)	2007-11-29	Isothermal strand displacement amplification using primers containing a non-regular base
KR920702866A (ko)	1992-10-28	핵산 증폭 방법
KR950701393A (ko)	1995-03-23	핵산 서열 증폭 방법, 이에 이용되는 조성물 및 키트(Nucleic Acide Sequence Amplification Method, Composition and Kit)
WO1991002818A1 (en)	1991-03-07	Enhanced nucleic acid amplification process
AU6301394A (en)	1994-06-30	Self-sustained, sequence replication system
AU2002352108A8 (en)	2003-06-10	Nucleic acid linkers and use thereof in gene synthesis
JPH08205894A (ja)	1996-08-13	核酸の高感度検出方法
EP1026261B1 (de)	2009-08-19	Erhöhung der Spezifität von Nukleinsäureamplifizierungen durch Trägernukleinsäuren
AU724804B2 (en)	2000-09-28	Assay involving looped nucleic acid
ATE307901T1 (de)	2005-11-15	Amplifikation und sequenzierung von primer-paaren und deren verwendung
KR102900467B1 (ko)	2025-12-19	토홀드 매개 가닥 치환 기반의 rpa-crispr 핵산 검출용 조성물 및 검출 방법
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JP2020096564A (ja)	2020-06-25	Ｒｎａ検出方法、ｒｎａ検出用核酸及びｒｎａ検出用キット
CA2102963A1 (en)	1994-05-18	Simple nucleic acid amplification
Del Prado et al.	2025	Novel primer-less amplification method for detection of RNA molecules
CN119040434A (zh)	2024-11-29	一种基于dI修饰引物的单链DNA合成技术
JP2007267636A (ja)	2007-10-18	核酸製造法および核酸増幅用プライマーセット
IE20030655A1 (en)	2005-03-23	Method for isothermal amplication of nucleic acid
JPH08228784A (ja)	1996-09-10	改良された転写方法