ATE206467T1 - 'terminal repeat'- amplifikation - Google Patents

'terminal repeat'- amplifikation

Info

Publication number: ATE206467T1
Authority: AT; Austria
Prior art keywords: rna; dna; template; sequence; promoter
Prior art date: 1994-11-28

Application number

AT95940256T

Other languages

English (en)

Inventor

Roy Sooknanan

Lawrence Malek

Original Assignee

Akzo Nobel Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-11-28

Filing date

1995-11-28

Publication date

2001-10-15

1995-11-28 Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv

2001-10-15 Application granted granted Critical

2001-10-15 Publication of ATE206467T1 publication Critical patent/ATE206467T1/de

Links

230000003321 amplification Effects 0.000 title abstract 2
238000003199 nucleic acid amplification method Methods 0.000 title abstract 2
108091032973 (ribonucleotides)n+m Proteins 0.000 abstract 8
108020004414 DNA Proteins 0.000 abstract 8
230000000295 complement effect Effects 0.000 abstract 5
230000000977 initiatory effect Effects 0.000 abstract 5
238000000034 method Methods 0.000 abstract 4
102000016928 DNA-directed DNA polymerase Human genes 0.000 abstract 3
108010014303 DNA-directed DNA polymerase Proteins 0.000 abstract 3
102000004163 DNA-directed RNA polymerases Human genes 0.000 abstract 3
108090000626 DNA-directed RNA polymerases Proteins 0.000 abstract 3
108091028043 Nucleic acid sequence Proteins 0.000 abstract 3
150000007523 nucleic acids Chemical group 0.000 abstract 3
230000037452 priming Effects 0.000 abstract 3
102000053602 DNA Human genes 0.000 abstract 2
102000006382 Ribonucleases Human genes 0.000 abstract 2
108010083644 Ribonucleases Proteins 0.000 abstract 2
239000003153 chemical reaction reagent Substances 0.000 abstract 2
239000012429 reaction media Substances 0.000 abstract 2
102000040650 (ribonucleotides)n+m Human genes 0.000 abstract 1
NYHBQMYGNKIUIF-UUOKFMHZSA-N Guanosine Chemical compound C1=NC=2C(=O)NC(N)=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O NYHBQMYGNKIUIF-UUOKFMHZSA-N 0.000 abstract 1
239000005549 deoxyribonucleoside Substances 0.000 abstract 1
230000003301 hydrolyzing effect Effects 0.000 abstract 1
239000002342 ribonucleoside Substances 0.000 abstract 1
239000001226 triphosphate Substances 0.000 abstract 1
235000011178 triphosphate Nutrition 0.000 abstract 1
125000002264 triphosphate group Chemical class [H]OP(=O)(O[H])OP(=O)(O[H])OP(=O)(O[H])O* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Wood Science & Technology (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Physics & Mathematics (AREA)
Chemical Kinetics & Catalysis (AREA)
Biophysics (AREA)
Analytical Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Oscillators With Electromechanical Resonators (AREA)
Amplifiers (AREA)
Steroid Compounds (AREA)
Electrotherapy Devices (AREA)
Channel Selection Circuits, Automatic Tuning Circuits (AREA)
Seal Device For Vehicle (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Peptides Or Proteins (AREA)

AT95940256T 1994-11-28 1995-11-28 'terminal repeat'- amplifikation ATE206467T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/345,505 US5665545A (en)	1994-11-28	1994-11-28	Terminal repeat amplification method
PCT/EP1995/004694 WO1996017079A1 (en)	1994-11-28	1995-11-28	Terminal repeat amplification method

Publications (1)

Publication Number	Publication Date
ATE206467T1 true ATE206467T1 (de)	2001-10-15

Family

ID=23355318

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95940256T ATE206467T1 (de)	1994-11-28	1995-11-28	'terminal repeat'- amplifikation

Country Status (10)

Country	Link
US (1)	US5665545A (de)
EP (1)	EP0796343B1 (de)
JP (1)	JP3745774B2 (de)
AT (1)	ATE206467T1 (de)
AU (1)	AU711589B2 (de)
CA (1)	CA2205563A1 (de)
DE (1)	DE69523068T2 (de)
ES (1)	ES2168112T3 (de)
FI (1)	FI972238A7 (de)
WO (1)	WO1996017079A1 (de)

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US6864050B2 (en) *	1999-07-30	2005-03-08	Affymetrix, Inc.	Single-phase amplification of nucleic acids
DK1218542T3 (da) *	1999-09-13	2004-08-02	Nugen Technologies Inc	Fremgangsmåder og sammensætninger til lineær isotermisk amplifikation af polynukleotidsekvenser
US6692918B2 (en) *	1999-09-13	2004-02-17	Nugen Technologies, Inc.	Methods and compositions for linear isothermal amplification of polynucleotide sequences
CA2412721A1 (en) *	2000-06-26	2002-01-03	Nugen Technologies, Inc.	Methods and compositions for transcription-based nucleic acid amplification
US7846733B2 (en)	2000-06-26	2010-12-07	Nugen Technologies, Inc.	Methods and compositions for transcription-based nucleic acid amplification
CA2430329A1 (en)	2000-12-13	2002-06-20	Nugen Technologies, Inc.	Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof
MXPA02012739A (es)	2001-03-09	2004-04-20	Nugen Technologies Inc	Metodos y composiciones para amplificacion de secuencias de arn.
US7094536B2 (en) *	2001-03-09	2006-08-22	Nugen Technologies, Inc.	Methods and compositions for amplification of RNA sequences
US8137911B2 (en) *	2001-05-22	2012-03-20	Cellscript, Inc.	Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
WO2004059289A2 (en) *	2001-05-22	2004-07-15	Epicentre Technologies	Target-dependent transcription using deletion mutants of n4 rna polymerase
WO2003020979A1 (en) *	2001-08-31	2003-03-13	Rosetta Inpharmactis Llc.	Methods for preparing nucleic acid samples
JP2005519621A (ja) *	2002-03-11	2005-07-07	ニューゲンテクノロジーズ，インコーポレイテッド	３’一本鎖部分を含む二本鎖ｄｎａを生成する方法および組換えのためのこれらの複合体の使用
SE0202867D0 (sv) *	2002-09-27	2002-09-27	Pyrosequencing Ab	New sequencing method
WO2004048594A2 (en)	2002-11-21	2004-06-10	Epicentre Technologies	Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
US7402386B2 (en)	2003-04-14	2008-07-22	Nugen Technologies, Inc.	Global amplification using random priming by a composite primer
US7642055B2 (en) *	2004-09-21	2010-01-05	Applied Biosystems, Llc	Two-color real-time/end-point quantitation of microRNAs (miRNAs)
WO2006081222A2 (en) *	2005-01-25	2006-08-03	Compass Genetics, Llc.	Isothermal dna amplification
CA2621267A1 (en)	2005-09-07	2007-03-15	Nugen Technologies, Inc.	Improved nucleic acid amplification procedure
US7501254B2 (en)	2006-07-20	2009-03-10	Ghc Technologies, Inc.	Methods and compositions for amplification and capture of nucleic acid sequences
US8039214B2 (en) *	2007-06-29	2011-10-18	Cellscript, Inc.	Synthesis of tagged nucleic acids
US8034568B2 (en)	2008-02-12	2011-10-11	Nugen Technologies, Inc.	Isothermal nucleic acid amplification methods and compositions
WO2009117698A2 (en)	2008-03-21	2009-09-24	Nugen Technologies, Inc.	Methods of rna amplification in the presence of dna
JP5481841B2 (ja) *	2008-11-28	2014-04-23	東ソー株式会社	サイトケラチン１９ｍＲＮＡの測定方法
WO2012019168A2 (en)	2010-08-06	2012-02-09	Moderna Therapeutics, Inc.	Engineered nucleic acids and methods of use thereof
EP2625189B1 (de)	2010-10-01	2018-06-27	ModernaTX, Inc.	Manipulierte nukleinsäuren und anwendungsverfahren dafür
EP3567121B1 (de)	2011-01-17	2023-08-30	Life Technologies Corporation	Arbeitsablauf zum nachweis von liganden mit nukleinsäuren
AU2012236099A1 (en)	2011-03-31	2013-10-03	Moderna Therapeutics, Inc.	Delivery and formulation of engineered nucleic acids
US9464124B2 (en)	2011-09-12	2016-10-11	Moderna Therapeutics, Inc.	Engineered nucleic acids and methods of use thereof
DE19216461T1 (de)	2011-10-03	2021-10-07	Modernatx, Inc.	Modifizierte nukleoside, nukleotide und nukleinsäuren und verwendungen davon
CA3018046A1 (en)	2011-12-16	2013-06-20	Moderna Therapeutics, Inc.	Modified nucleoside, nucleotide, and nucleic acid compositions
US9283287B2 (en)	2012-04-02	2016-03-15	Moderna Therapeutics, Inc.	Modified polynucleotides for the production of nuclear proteins
WO2013151665A2 (en)	2012-04-02	2013-10-10	modeRNA Therapeutics	Modified polynucleotides for the production of proteins associated with human disease
US9254311B2 (en)	2012-04-02	2016-02-09	Moderna Therapeutics, Inc.	Modified polynucleotides for the production of proteins
US9572897B2 (en)	2012-04-02	2017-02-21	Modernatx, Inc.	Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
CN102943100B (zh) *	2012-11-23	2014-04-16	郑州安图生物工程股份有限公司	高效RNA逆转录合成cDNA的方法
PL2922554T3 (pl)	2012-11-26	2022-06-20	Modernatx, Inc.	Na zmodyfikowany na końcach
US8980864B2 (en)	2013-03-15	2015-03-17	Moderna Therapeutics, Inc.	Compositions and methods of altering cholesterol levels
EP3052521A1 (de)	2013-10-03	2016-08-10	Moderna Therapeutics, Inc.	Polynukleotide zur codierung von low-density-lipoprotein-rezeptor
GB2550712B (en) *	2015-02-26	2021-01-13	Hitachi High Tech Corp	Method for constructing hairpin-containing nucleic acid molecules for nanopore sequencing
NL2022993B1 (en) *	2019-04-23	2020-11-02	Synvolux Ip Bv	Methods and compositions for isothermal DNA amplification
US12612658B2 (en)	2019-07-10	2026-04-28	The Board Of Trustees Of The Leland Stanford Junior University	RNA replication using transcription polymerases

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US4683202A (en) *	1985-03-28	1987-07-28	Cetus Corporation	Process for amplifying nucleic acid sequences
CA1340807C (en) *	1988-02-24	1999-11-02	Lawrence T. Malek	Nucleic acid amplification process
US5130238A (en) *	1988-06-24	1992-07-14	Cangene Corporation	Enhanced nucleic acid amplification process
WO1990002819A1 (en) *	1988-09-08	1990-03-22	The Salk Institute For Biological Studies	Replicative rna-based amplification detection systems
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NO904633L (no) *	1989-11-09	1991-05-10	Molecular Diagnostics Inc	Amplifikasjon av nukleinsyrer ved transkriberbar haarnaalsprobe.
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DE4213029A1 (de) *	1991-09-26	1993-04-01	Boehringer Mannheim Gmbh	Verfahren zur spezifischen vervielfaeltigung von nukleins aeuresequenzen
DE4132133A1 (de) *	1991-09-26	1993-04-01	Boehringer Mannheim Gmbh	Verfahren zur spezifischen herstellung von ribonukleinsaeuren
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1994
- 1994-11-28 US US08/345,505 patent/US5665545A/en not_active Expired - Fee Related
1995
- 1995-11-28 ES ES95940256T patent/ES2168112T3/es not_active Expired - Lifetime
- 1995-11-28 DE DE69523068T patent/DE69523068T2/de not_active Expired - Fee Related
- 1995-11-28 AU AU41767/96A patent/AU711589B2/en not_active Ceased
- 1995-11-28 CA CA002205563A patent/CA2205563A1/en not_active Abandoned
- 1995-11-28 EP EP95940256A patent/EP0796343B1/de not_active Expired - Lifetime
- 1995-11-28 WO PCT/EP1995/004694 patent/WO1996017079A1/en not_active Ceased
- 1995-11-28 AT AT95940256T patent/ATE206467T1/de not_active IP Right Cessation
- 1995-11-28 JP JP51818496A patent/JP3745774B2/ja not_active Expired - Fee Related
1997
- 1997-05-27 FI FI972238A patent/FI972238A7/fi unknown

Also Published As

Publication number	Publication date
WO1996017079A1 (en)	1996-06-06
CA2205563A1 (en)	1996-06-06
ES2168112T3 (es)	2002-06-01
AU711589B2 (en)	1999-10-14
DE69523068D1 (en)	2001-11-08
JP3745774B2 (ja)	2006-02-15
FI972238A0 (fi)	1997-05-27
JPH10510161A (ja)	1998-10-06
DE69523068T2 (de)	2002-06-06
EP0796343B1 (de)	2001-10-04
FI972238A7 (fi)	1997-05-27
US5665545A (en)	1997-09-09
EP0796343A1 (de)	1997-09-24
AU4176796A (en)	1996-06-19

Legal Events

Date	Code	Title	Description
2002-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69523068D1 (en)	2001-11-08	'terminal repeat'- amplifikation
US5916779A (en)	1999-06-29	Strand displacement amplification of RNA targets
CN101203618B (zh)	2013-03-13	使用含有非常规碱基的引物的等温链置换扩增
EP1256630B1 (de)	2008-06-18	Selektive Polymerasekettenreaktion von DNA, deren Basensequenz vollständig unbekannt ist
JP3867926B2 (ja)	2007-01-17	核酸の増幅法
KR920702866A (ko)	1992-10-28	핵산 증폭 방법
KR950701393A (ko)	1995-03-23	핵산 서열 증폭 방법, 이에 이용되는 조성물 및 키트(Nucleic Acide Sequence Amplification Method, Composition and Kit)
WO1991002818A1 (en)	1991-03-07	Enhanced nucleic acid amplification process
EP0373960A3 (de)	1991-04-10	4 Selbstfortsetzendes System für Sequenzreplikation
AU2002352108A8 (en)	2003-06-10	Nucleic acid linkers and use thereof in gene synthesis
JPH08205894A (ja)	1996-08-13	核酸の高感度検出方法
EP1026261B1 (de)	2009-08-19	Erhöhung der Spezifität von Nukleinsäureamplifizierungen durch Trägernukleinsäuren
EP0855447A3 (de)	1999-04-14	Verfahren zur Bestimmung von Nukleinsäuresequenzen
AU724804B2 (en)	2000-09-28	Assay involving looped nucleic acid
ATE307901T1 (de)	2005-11-15	Amplifikation und sequenzierung von primer-paaren und deren verwendung
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JP2020096564A (ja)	2020-06-25	Ｒｎａ検出方法、ｒｎａ検出用核酸及びｒｎａ検出用キット
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CN119040434A (zh)	2024-11-29	一种基于dI修饰引物的单链DNA合成技术
JP2007267636A (ja)	2007-10-18	核酸製造法および核酸増幅用プライマーセット
IE20030655A1 (en)	2005-03-23	Method for isothermal amplication of nucleic acid
JPH08228784A (ja)	1996-09-10	改良された転写方法