ATE206467T1 - 'terminal repeat'- amplifikation - Google Patents

'terminal repeat'- amplifikation

Info

Publication number: ATE206467T1
Authority: AT; Austria
Prior art keywords: rna; dna; template; sequence; promoter
Prior art date: 1994-11-28

Application number

AT95940256T

Other languages

English (en)

Inventor

Roy Sooknanan

Lawrence Malek

Original Assignee

Akzo Nobel Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-11-28

Filing date

1995-11-28

Publication date

2001-10-15

1995-11-28 Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv

2001-10-15 Application granted granted Critical

2001-10-15 Publication of ATE206467T1 publication Critical patent/ATE206467T1/de

Links

230000003321 amplification Effects 0.000 title abstract 2
238000003199 nucleic acid amplification method Methods 0.000 title abstract 2
108091032973 (ribonucleotides)n+m Proteins 0.000 abstract 8
108020004414 DNA Proteins 0.000 abstract 8
230000000295 complement effect Effects 0.000 abstract 5
230000000977 initiatory effect Effects 0.000 abstract 5
238000000034 method Methods 0.000 abstract 4
102000016928 DNA-directed DNA polymerase Human genes 0.000 abstract 3
108010014303 DNA-directed DNA polymerase Proteins 0.000 abstract 3
102000004163 DNA-directed RNA polymerases Human genes 0.000 abstract 3
108090000626 DNA-directed RNA polymerases Proteins 0.000 abstract 3
108091028043 Nucleic acid sequence Proteins 0.000 abstract 3
150000007523 nucleic acids Chemical group 0.000 abstract 3
230000037452 priming Effects 0.000 abstract 3
102000053602 DNA Human genes 0.000 abstract 2
102000006382 Ribonucleases Human genes 0.000 abstract 2
108010083644 Ribonucleases Proteins 0.000 abstract 2
239000003153 chemical reaction reagent Substances 0.000 abstract 2
239000012429 reaction media Substances 0.000 abstract 2
102000040650 (ribonucleotides)n+m Human genes 0.000 abstract 1
NYHBQMYGNKIUIF-UUOKFMHZSA-N Guanosine Chemical compound C1=NC=2C(=O)NC(N)=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O NYHBQMYGNKIUIF-UUOKFMHZSA-N 0.000 abstract 1
239000005549 deoxyribonucleoside Substances 0.000 abstract 1
230000003301 hydrolyzing effect Effects 0.000 abstract 1
239000002342 ribonucleoside Substances 0.000 abstract 1
239000001226 triphosphate Substances 0.000 abstract 1
235000011178 triphosphate Nutrition 0.000 abstract 1
125000002264 triphosphate group Chemical class [H]OP(=O)(O[H])OP(=O)(O[H])OP(=O)(O[H])O* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Wood Science & Technology (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Physics & Mathematics (AREA)
Chemical Kinetics & Catalysis (AREA)
Biophysics (AREA)
Analytical Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Seal Device For Vehicle (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Peptides Or Proteins (AREA)
Amplifiers (AREA)
Oscillators With Electromechanical Resonators (AREA)
Steroid Compounds (AREA)
Electrotherapy Devices (AREA)
Channel Selection Circuits, Automatic Tuning Circuits (AREA)

AT95940256T 1994-11-28 1995-11-28 'terminal repeat'- amplifikation ATE206467T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/345,505 US5665545A (en)	1994-11-28	1994-11-28	Terminal repeat amplification method
PCT/EP1995/004694 WO1996017079A1 (en)	1994-11-28	1995-11-28	Terminal repeat amplification method

Publications (1)

Publication Number	Publication Date
ATE206467T1 true ATE206467T1 (de)	2001-10-15

Family

ID=23355318

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95940256T ATE206467T1 (de)	1994-11-28	1995-11-28	'terminal repeat'- amplifikation

Country Status (10)

Country	Link
US (1)	US5665545A (de)
EP (1)	EP0796343B1 (de)
JP (1)	JP3745774B2 (de)
AT (1)	ATE206467T1 (de)
AU (1)	AU711589B2 (de)
CA (1)	CA2205563A1 (de)
DE (1)	DE69523068T2 (de)
ES (1)	ES2168112T3 (de)
FI (1)	FI972238A7 (de)
WO (1)	WO1996017079A1 (de)

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CA2384838C (en) *	1999-09-13	2006-07-18	Nugen Technologies, Inc.	Methods and compositions for linear isothermal amplification of polynucleotide sequences
ATE455186T1 (de) *	2000-06-26	2010-01-15	Nugen Technologies Inc	Methoden und zusammensetzungen zur auf transkription basierenden vervielfältigung von nukleinsäuren
US7846733B2 (en)	2000-06-26	2010-12-07	Nugen Technologies, Inc.	Methods and compositions for transcription-based nucleic acid amplification
WO2002048402A2 (en)	2000-12-13	2002-06-20	Nugen Technologies, Inc.	Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof
CA2439074A1 (en) *	2001-03-09	2002-09-19	Nugen Technologies, Inc.	Methods and compositions for amplification of rna sequences
KR20030082535A (ko)	2001-03-09	2003-10-22	뉴젠 테크놀로지스 인코포레이티드	Ｒｎａ 서열의 증폭을 위한 방법 및 조성물
WO2004059289A2 (en) *	2001-05-22	2004-07-15	Epicentre Technologies	Target-dependent transcription using deletion mutants of n4 rna polymerase
US8137911B2 (en) *	2001-05-22	2012-03-20	Cellscript, Inc.	Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
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US7413857B2 (en) *	2002-11-21	2008-08-19	Epicentre Technologies	Methods for using riboprimers for strand displacement replication of target sequences
JP2006523465A (ja)	2003-04-14	2006-10-19	ニューゲンテクノロジーズ，インコーポレイテッド	ランダムにプライミングされる複合プライマーを用いる大規模増幅
EP1791982B1 (de) *	2004-09-21	2011-01-05	Life Technologies Corporation	Zweifarbige echtzeit/endpunkt-quantifizierung von mikro-rnas (mirnas)
WO2006081222A2 (en) *	2005-01-25	2006-08-03	Compass Genetics, Llc.	Isothermal dna amplification
US7939258B2 (en)	2005-09-07	2011-05-10	Nugen Technologies, Inc.	Nucleic acid amplification procedure using RNA and DNA composite primers
US7501254B2 (en)	2006-07-20	2009-03-10	Ghc Technologies, Inc.	Methods and compositions for amplification and capture of nucleic acid sequences
EP2173872B1 (de)	2007-06-29	2014-04-02	CellScript, Inc.	Copy-dna und sense-rna
US8034568B2 (en)	2008-02-12	2011-10-11	Nugen Technologies, Inc.	Isothermal nucleic acid amplification methods and compositions
GB2470672B (en)	2008-03-21	2012-09-12	Nugen Technologies Inc	Methods of RNA amplification in the presence of DNA
JP5481841B2 (ja) *	2008-11-28	2014-04-23	東ソー株式会社	サイトケラチン１９ｍＲＮＡの測定方法
CA2807552A1 (en)	2010-08-06	2012-02-09	Moderna Therapeutics, Inc.	Engineered nucleic acids and methods of use thereof
ES3005233T3 (en)	2010-10-01	2025-03-14	Modernatx Inc	Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
ES2632768T3 (es)	2011-01-17	2017-09-15	Life Technologies Corporation	Flujo de trabajo para la detección de ligandos empleando ácidos nucleicos
JP2014511687A (ja)	2011-03-31	2014-05-19	モデルナセラピューティクスインコーポレイテッド	工学操作された核酸の送達および製剤
US9464124B2 (en)	2011-09-12	2016-10-11	Moderna Therapeutics, Inc.	Engineered nucleic acids and methods of use thereof
EP2763701B1 (de)	2011-10-03	2018-12-19	Moderna Therapeutics, Inc.	Modifizierte nukleoside, nukleotide und nukleinsäuren und verwendungen davon
JP2015501844A (ja)	2011-12-16	2015-01-19	モデルナセラピューティクスインコーポレイテッドＭｏｄｅｒｎａＴｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ．	修飾ヌクレオシド、ヌクレオチドおよび核酸組成物
WO2013151663A1 (en)	2012-04-02	2013-10-10	modeRNA Therapeutics	Modified polynucleotides for the production of membrane proteins
US9572897B2 (en)	2012-04-02	2017-02-21	Modernatx, Inc.	Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9254311B2 (en)	2012-04-02	2016-02-09	Moderna Therapeutics, Inc.	Modified polynucleotides for the production of proteins
US9283287B2 (en)	2012-04-02	2016-03-15	Moderna Therapeutics, Inc.	Modified polynucleotides for the production of nuclear proteins
CN102943100B (zh) *	2012-11-23	2014-04-16	郑州安图生物工程股份有限公司	高效RNA逆转录合成cDNA的方法
ES2921623T3 (es)	2012-11-26	2022-08-30	Modernatx Inc	ARN modificado terminalmente
US8980864B2 (en)	2013-03-15	2015-03-17	Moderna Therapeutics, Inc.	Compositions and methods of altering cholesterol levels
KR20160067219A (ko)	2013-10-03	2016-06-13	모더나 세라퓨틱스, 인코포레이티드	저밀도 지단백질 수용체를 암호화하는 폴리뉴클레오타이드
JP6560336B2 (ja) *	2015-02-26	2019-08-14	株式会社日立ハイテクノロジーズ	核酸分子の構築方法
NL2022993B1 (en) *	2019-04-23	2020-11-02	Synvolux Ip Bv	Methods and compositions for isothermal DNA amplification
US12612658B2 (en)	2019-07-10	2026-04-28	The Board Of Trustees Of The Leland Stanford Junior University	RNA replication using transcription polymerases

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CA1340807C (en) *	1988-02-24	1999-11-02	Lawrence T. Malek	Nucleic acid amplification process
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1994
- 1994-11-28 US US08/345,505 patent/US5665545A/en not_active Expired - Fee Related
1995
- 1995-11-28 WO PCT/EP1995/004694 patent/WO1996017079A1/en not_active Ceased
- 1995-11-28 EP EP95940256A patent/EP0796343B1/de not_active Expired - Lifetime
- 1995-11-28 ES ES95940256T patent/ES2168112T3/es not_active Expired - Lifetime
- 1995-11-28 AT AT95940256T patent/ATE206467T1/de not_active IP Right Cessation
- 1995-11-28 CA CA002205563A patent/CA2205563A1/en not_active Abandoned
- 1995-11-28 JP JP51818496A patent/JP3745774B2/ja not_active Expired - Fee Related
- 1995-11-28 AU AU41767/96A patent/AU711589B2/en not_active Ceased
- 1995-11-28 DE DE69523068T patent/DE69523068T2/de not_active Expired - Fee Related
1997
- 1997-05-27 FI FI972238A patent/FI972238A7/fi unknown

Also Published As

Publication number	Publication date
CA2205563A1 (en)	1996-06-06
DE69523068T2 (de)	2002-06-06
EP0796343B1 (de)	2001-10-04
FI972238A0 (fi)	1997-05-27
ES2168112T3 (es)	2002-06-01
AU711589B2 (en)	1999-10-14
JP3745774B2 (ja)	2006-02-15
FI972238A7 (fi)	1997-05-27
EP0796343A1 (de)	1997-09-24
WO1996017079A1 (en)	1996-06-06
DE69523068D1 (en)	2001-11-08
JPH10510161A (ja)	1998-10-06
AU4176796A (en)	1996-06-19
US5665545A (en)	1997-09-09

Legal Events

Date	Code	Title	Description
2002-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69523068D1 (en)	2001-11-08	'terminal repeat'- amplifikation
US5916779A (en)	1999-06-29	Strand displacement amplification of RNA targets
CN101203618B (zh)	2013-03-13	使用含有非常规碱基的引物的等温链置换扩增
EP1256630B1 (de)	2008-06-18	Selektive Polymerasekettenreaktion von DNA, deren Basensequenz vollständig unbekannt ist
JP3867926B2 (ja)	2007-01-17	核酸の増幅法
KR920702866A (ko)	1992-10-28	핵산 증폭 방법
KR950701393A (ko)	1995-03-23	핵산 서열 증폭 방법, 이에 이용되는 조성물 및 키트(Nucleic Acide Sequence Amplification Method, Composition and Kit)
WO1991002818A1 (en)	1991-03-07	Enhanced nucleic acid amplification process
AU6301394A (en)	1994-06-30	Self-sustained, sequence replication system
JPH0358785A (ja)	1991-03-13	核酸増幅反応の汚染を制御する方法
EP1026261B1 (de)	2009-08-19	Erhöhung der Spezifität von Nukleinsäureamplifizierungen durch Trägernukleinsäuren
EP0855447A3 (de)	1999-04-14	Verfahren zur Bestimmung von Nukleinsäuresequenzen
AU724804B2 (en)	2000-09-28	Assay involving looped nucleic acid
DE60023480D1 (de)	2005-12-01	Amplifikation und sequenzierung von primer-paaren und deren verwendung
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CN119040434A (zh)	2024-11-29	一种基于dI修饰引物的单链DNA合成技术
JP2007267636A (ja)	2007-10-18	核酸製造法および核酸増幅用プライマーセット
IE20030655A1 (en)	2005-03-23	Method for isothermal amplication of nucleic acid
JPH08228784A (ja)	1996-09-10	改良された転写方法