ATE206706T1 - Sulfonamidderivate von azolonen als anti- helicobacter-mittel - Google Patents

Sulfonamidderivate von azolonen als anti- helicobacter-mittel

Info

Publication number
ATE206706T1
ATE206706T1 AT95925838T AT95925838T ATE206706T1 AT E206706 T1 ATE206706 T1 AT E206706T1 AT 95925838 T AT95925838 T AT 95925838T AT 95925838 T AT95925838 T AT 95925838T AT E206706 T1 ATE206706 T1 AT E206706T1
Authority
AT
Austria
Prior art keywords
image
4alkyl
compounds
azolones
sulfonamide derivatives
Prior art date
Application number
AT95925838T
Other languages
English (en)
Inventor
Jan Heeres
Raymond Antoine Stokbroekx
Joseph Hector Mostmans
Der Veken Louis Jozef Elis Van
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE206706T1 publication Critical patent/ATE206706T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Lubricants (AREA)
AT95925838T 1994-07-12 1995-07-05 Sulfonamidderivate von azolonen als anti- helicobacter-mittel ATE206706T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94202015 1994-07-12
PCT/EP1995/002619 WO1996001818A1 (en) 1994-07-12 1995-07-05 Sulfonamide derivatives of azolones anti-helicobacter agents

Publications (1)

Publication Number Publication Date
ATE206706T1 true ATE206706T1 (de) 2001-10-15

Family

ID=8217029

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95925838T ATE206706T1 (de) 1994-07-12 1995-07-05 Sulfonamidderivate von azolonen als anti- helicobacter-mittel

Country Status (21)

Country Link
US (2) US5571811A (de)
EP (1) EP0770071B1 (de)
JP (1) JPH10502386A (de)
CN (1) CN1068878C (de)
AT (1) ATE206706T1 (de)
AU (1) AU684981B2 (de)
BR (1) BR9508376A (de)
CA (1) CA2194562A1 (de)
CZ (1) CZ2997A3 (de)
DE (1) DE69523159T2 (de)
FI (1) FI970113L (de)
HU (1) HUT76636A (de)
IL (1) IL114537A (de)
MX (1) MX9700340A (de)
NO (1) NO970089L (de)
NZ (1) NZ289853A (de)
PL (1) PL318149A1 (de)
SK (1) SK4497A3 (de)
TW (1) TW341571B (de)
WO (1) WO1996001818A1 (de)
ZA (1) ZA955760B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5571811A (en) * 1994-07-12 1996-11-05 Janssen Pharmaceutica N.V. Sulfonamide derivatives of azolones
US5637592A (en) * 1994-07-12 1997-06-10 Janssen Pharmaceutica N.V. Acyl derivatives of azolones
US5639754A (en) * 1994-07-12 1997-06-17 Janssen Pharmaceutica N.V. Urea and thiourea derivatives of azolones
KR100484326B1 (ko) 1999-03-17 2005-04-20 모리나가 세이카 가부시키가이샤 코코아 성분을 함유하는 음식물
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6369087B1 (en) * 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6780880B1 (en) 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
US20050119251A1 (en) * 2001-12-21 2005-06-02 Jian-Min Fu Nicotinamide derivatives and their use as therapeutic agents
ES2387617T3 (es) * 2002-11-14 2012-09-27 Aderans Research Institute, Inc. Cultivo de células inductoras de cabello
EP1608373A4 (de) * 2003-03-19 2010-09-29 Exelixis Inc Tie-2 modulatoren und anwendungsverfahren
US8071603B2 (en) * 2004-09-20 2011-12-06 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
CA2580855A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
MX2007003327A (es) 2004-09-20 2007-06-05 Xenon Pharmaceuticals Inc Derivados heterociclicos, y su uso como mediadores de estearoil-coa desaturasa.
WO2006034341A2 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Pyridazine derivatives for inhibiting human stearoyl-coa-desaturase
MX2007003329A (es) * 2004-09-20 2007-06-05 Xenon Pharmaceuticals Inc Derivados heterociclicos y biciclicos y su uso como inhibidores de estearoil-coa-desaturasa (scd).
JP4958787B2 (ja) * 2004-09-20 2012-06-20 ゼノン・ファーマシューティカルズ・インコーポレイテッド ヒトステアロイル−ＣｏＡデサチュラーゼを阻害するためのピリジン誘導体
BRPI0515482A (pt) 2004-09-20 2008-07-22 Xenon Pharmaceuticals Inc derivados heterocìclicos e seus usos como agentes terapêuticos
AR051026A1 (es) 2004-09-20 2006-12-13 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
TW200626138A (en) 2004-09-20 2006-08-01 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as therapeutic agents
US8541457B2 (en) 2005-06-03 2013-09-24 Xenon Pharmaceuticals Inc. Aminothiazole derivatives as human stearoyl-CoA desaturase inhibitors
KR20210113648A (ko) * 2019-01-06 2021-09-16 소마젠 인크 Ｈｔｒａ 저해제 및 ｃａｇａ 저해제 및 이의 용도

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1292472C (en) * 1985-12-03 1991-11-26 Alfonsus Guilielmus Knaeps Derivatives of ¬¬4-¬4-(4-phenyl-1-piperazinyl)- phenoxymethyl|-1,3-dioxolan-2-yl|methyl|-1h-imidazoles and 1h-1,2,4-triazoles
US4791111A (en) * 1985-12-23 1988-12-13 Janssen Pharmaceutica, N.V. [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles having anti-microbial properties
CA1331757C (en) * 1988-02-29 1994-08-30 Janssen Pharmaceutica Naamloze Vennootschap 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols
CA2076257A1 (en) * 1991-09-13 1993-03-14 Jan Heeres 4-¬4-¬4-(4-hydroxyphenyl)-1- piperazinyl|phenyl|-5-methyl-3h -1,2,4-triazol-3-one derivatives
US5571811A (en) * 1994-07-12 1996-11-05 Janssen Pharmaceutica N.V. Sulfonamide derivatives of azolones

Also Published As

Publication number Publication date
ZA955760B (en) 1997-01-13
FI970113A0 (fi) 1997-01-10
NO970089L (no) 1997-03-10
US5571811A (en) 1996-11-05
JPH10502386A (ja) 1998-03-03
NZ289853A (en) 1997-11-24
IL114537A (en) 1999-04-11
IL114537A0 (en) 1995-11-27
FI970113A7 (fi) 1997-01-10
PL318149A1 (en) 1997-05-12
DE69523159T2 (de) 2002-06-20
BR9508376A (pt) 1997-10-28
MX9700340A (es) 1997-05-31
HU9700080D0 (en) 1997-02-28
DE69523159D1 (de) 2001-11-15
EP0770071A1 (de) 1997-05-02
FI970113L (fi) 1997-01-10
SK4497A3 (en) 1997-12-10
HUT76636A (en) 1997-10-28
CN1068878C (zh) 2001-07-25
AU2981995A (en) 1996-02-09
AU684981B2 (en) 1998-01-08
TW341571B (en) 1998-10-01
CZ2997A3 (en) 1997-09-17
CN1152308A (zh) 1997-06-18
EP0770071B1 (de) 2001-10-10
CA2194562A1 (en) 1996-01-25
WO1996001818A1 (en) 1996-01-25
NO970089D0 (no) 1997-01-09
US5728700A (en) 1998-03-17

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties