ATE207364T1 - Caprin arthritis-enzephalitis virus enthaltende vakzine und verwendung zur immunschutz gegen hiv- 1 infektion - Google Patents

Caprin arthritis-enzephalitis virus enthaltende vakzine und verwendung zur immunschutz gegen hiv- 1 infektion

Info

Publication number
ATE207364T1
ATE207364T1 AT97916761T AT97916761T ATE207364T1 AT E207364 T1 ATE207364 T1 AT E207364T1 AT 97916761 T AT97916761 T AT 97916761T AT 97916761 T AT97916761 T AT 97916761T AT E207364 T1 ATE207364 T1 AT E207364T1
Authority
AT
Austria
Prior art keywords
infection
caev
arthritis
encephalitis virus
caprin
Prior art date
Application number
AT97916761T
Other languages
English (en)
Inventor
Angeline Douvas
Glenn Ehresmann
Original Assignee
Univ Southern California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/616,855 external-priority patent/US5770357A/en
Priority claimed from US08/616,854 external-priority patent/US6033672A/en
Application filed by Univ Southern California filed Critical Univ Southern California
Application granted granted Critical
Publication of ATE207364T1 publication Critical patent/ATE207364T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/21Retroviridae, e.g. equine infectious anemia virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/15011Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • AIDS & HIV (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
AT97916761T 1996-03-15 1997-03-14 Caprin arthritis-enzephalitis virus enthaltende vakzine und verwendung zur immunschutz gegen hiv- 1 infektion ATE207364T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/616,855 US5770357A (en) 1996-03-15 1996-03-15 Method of diagnosing caprine arthritis-encephalitis virus infection
US08/616,854 US6033672A (en) 1996-03-15 1996-03-15 Method of stimulating an immune response to caprine arthritis-encephalitis virus (CAEV) in humans through the administration of CAEV immunogens
PCT/US1997/004020 WO1997033615A2 (en) 1996-03-15 1997-03-14 Caprine arthritis-encephalitis virus provides immunoprotection against hiv-1 infection

Publications (1)

Publication Number Publication Date
ATE207364T1 true ATE207364T1 (de) 2001-11-15

Family

ID=27087888

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97916761T ATE207364T1 (de) 1996-03-15 1997-03-14 Caprin arthritis-enzephalitis virus enthaltende vakzine und verwendung zur immunschutz gegen hiv- 1 infektion

Country Status (11)

Country Link
EP (1) EP0910405B1 (de)
JP (1) JP2002503205A (de)
CN (1) CN1236818C (de)
AT (1) ATE207364T1 (de)
AU (1) AU732865B2 (de)
DE (1) DE69707680T2 (de)
DK (1) DK0910405T3 (de)
ES (1) ES2165042T3 (de)
PT (1) PT910405E (de)
RU (1) RU2194529C2 (de)
WO (1) WO1997033615A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6602505B2 (en) * 1998-04-30 2003-08-05 University Of Southern California Viral chimeras comprised of CAEV and HIV-1 genetic elements
WO2004024129A1 (en) * 2002-09-10 2004-03-25 Samir Chachoua Induced remission therapy
RU2345138C2 (ru) * 2006-12-25 2009-01-27 ФГУП Государственный научно-исследовательский институт особо чистых биопрепаратов ФМБА ЭКСПРЕССИОННАЯ ПЛАЗМИДНАЯ ДНК р-ВМС-gag(A)-hum ДЛЯ ЭКСПРЕССИИ БЕЛКА р55 ВИЧ-1 В КЛЕТКАХ ЭУКАРИОТ
CN107632153B (zh) * 2017-08-07 2019-05-24 新疆畜牧科学院 一种小反刍动物慢病毒间接elisa检测试剂盒
CN107488219A (zh) * 2017-08-07 2017-12-19 新疆畜牧科学院 一种山羊关节炎‑脑炎病毒血清抗体诊断标记蛋白gp135及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2634203B2 (ja) * 1987-09-04 1997-07-23 インターナショナル ミュレックス テクノロジーズ コーポレイション イムノアツセイおよびそれに使用される生物学的構築体
US5204259A (en) * 1988-05-06 1993-04-20 Pharmacia Genetic Engineering, Inc. Methods and systems for producing HIV antigens
US5470701A (en) * 1993-02-24 1995-11-28 The Regents Of The University Of California Method for determining favorable prognosis in an HIV positive subject using HLA-DR+ /CD38- CD8bright cells
FR2721618B1 (fr) * 1994-06-28 1996-09-13 Centre Nat Rech Scient Fragments d'acide nucléique et fragments peptidiques correspondants issus du génome du virus de l'arthrite et de l'encéphalite caprine (VAEC) et leurs applications.
FR2732346B1 (fr) * 1995-03-27 1997-05-30 Centre Nat Rech Scient Proteines mutees, codees par un gene env mute de lentivirus, fragments peptidiques inclus dans lesdites proteines, vecteurs d'expression exprimant lesdites proteines mutees et leurs applications

Also Published As

Publication number Publication date
AU732865B2 (en) 2001-05-03
PT910405E (pt) 2002-03-28
CN1219881A (zh) 1999-06-16
ES2165042T3 (es) 2002-03-01
EP0910405A2 (de) 1999-04-28
WO1997033615A3 (en) 1998-03-05
AU2529797A (en) 1997-10-01
EP0910405B1 (de) 2001-10-24
JP2002503205A (ja) 2002-01-29
WO1997033615A2 (en) 1997-09-18
DE69707680D1 (de) 2001-11-29
DE69707680T2 (de) 2002-07-11
DK0910405T3 (da) 2002-02-18
RU2194529C2 (ru) 2002-12-20
HK1021133A1 (en) 2000-06-02
CN1236818C (zh) 2006-01-18

Similar Documents

Publication Publication Date Title
ATE476983T1 (de) Immunostimulierende polynukleotide sequenzen zur verwendung bei der verhinderung und behandlung von viralen erkrankungen der atemwege
ES2176232T3 (es) Vacuna adecuada para ser utilizada en la prevencion y tratamiento de la infeccion por helicobacter.
ATE475423T1 (de) Immunostimulierende polynukleotide sequenzen zur verwendung bei der verhinderung und behandlung von viralen erkrankungen
ATE243750T1 (de) Leishmania-antigene zur anwendung in der leishmaniasis therapie und diagnose
NO940661L (no) Peptider for indusering av cytotoksisk T-lymfocytreaksjoner mot hepatit B virus
ATE207364T1 (de) Caprin arthritis-enzephalitis virus enthaltende vakzine und verwendung zur immunschutz gegen hiv- 1 infektion
EP0317622A4 (de) Verhütung und behandlung einer retrovirenkrankheit.
DE69232417D1 (de) Michellamine zur verwendung als antivirale wirkstoffe, zusammensetzung und behandlungsverfahren
EP1073461A4 (de) Virale chimären aus caev und hiv-1 genetischen elementen
DK0859613T3 (da) Anvendelse af flupirtin til forebyggelse og behandling af sygdomme, som er forbundet med beskadigelse af det hæmopoietiske cellesystem
CA2249736A1 (en) Caprine arthritis-encephalitis virus provides immunoprotection against hiv-1 infection
HUP0100937A2 (hu) Többszörösen elágazó peptidkonstrukciókat tartalmazó liposzómák és alkalmazásuk humán immundeficiencia vírus ellen
DK242889A (da) Laegemiddel i form af en ud fra de peyerske plaques fremstillet organekstrakt og dets anvendelse
RU94038588A (ru) Способ лечения вторичного иммунодефицита (вид)
WO1997026880A3 (en) Use of a combination of delavirdine and one or more protease inhibitors in hiv-1 infected patients
ATE293994T1 (de) Multivalente rekombinante antikörper zur behandlung von hrv infektionen
KR950702838A (ko) 인터루킨-4(IL-4)를 사용한 사람 면역결핍 바이러스(HIV) 복제의 억제방법(Method for inhibiting HIV replication using IL-4)
ATE111485T1 (de) Peptidbehandlung von hartnäckigen infektionskrankheiten.
EA199700353A1 (ru) Композиция и способ для определения приобретенного синдрома иммунодефицита, способ приготовления названной композиции
DE69734349D1 (de) Behandlung von knochenleiden mit adrenomedullin
DE60229624D1 (de) Peroxiredoxin-arzneistoffe zur behandlung einer hiv-1-infektion
DE69123252D1 (de) Kreuzreaktive immunisierung gegen influenza
ATE212839T1 (de) Hämoregulatorische verbindungen
ATE349532T1 (de) Zytotoxisches t-zellepitop des papillomavirus l1- proteins und seine verwendung in diagnostik und therapie

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee