ATE208425T1 - Kodierende sequenzen des menschlichen brca1-gens - Google Patents
Kodierende sequenzen des menschlichen brca1-gensInfo
- Publication number
- ATE208425T1 ATE208425T1 AT97907894T AT97907894T ATE208425T1 AT E208425 T1 ATE208425 T1 AT E208425T1 AT 97907894 T AT97907894 T AT 97907894T AT 97907894 T AT97907894 T AT 97907894T AT E208425 T1 ATE208425 T1 AT E208425T1
- Authority
- AT
- Austria
- Prior art keywords
- brca1
- coding sequences
- gene
- brca1 gene
- sequences
- Prior art date
Links
- 101100437864 Homo sapiens BRCA1 gene Proteins 0.000 title 1
- 101150072950 BRCA1 gene Proteins 0.000 abstract 5
- 102000036365 BRCA1 Human genes 0.000 abstract 3
- 108700020463 BRCA1 Proteins 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 108700040618 BRCA1 Genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 206010006187 Breast cancer Diseases 0.000 abstract 1
- 208000026310 Breast neoplasm Diseases 0.000 abstract 1
- 108091026890 Coding region Proteins 0.000 abstract 1
- 108091035707 Consensus sequence Proteins 0.000 abstract 1
- 208000034826 Genetic Predisposition to Disease Diseases 0.000 abstract 1
- 206010033128 Ovarian cancer Diseases 0.000 abstract 1
- 206010061535 Ovarian neoplasm Diseases 0.000 abstract 1
- 210000000481 breast Anatomy 0.000 abstract 1
- 238000001415 gene therapy Methods 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/598,591 US5654155A (en) | 1996-02-12 | 1996-02-12 | Consensus sequence of the human BRCA1 gene |
| PCT/US1997/003038 WO1997029213A1 (en) | 1996-02-12 | 1997-02-12 | Coding sequences of the human brca1 gene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE208425T1 true ATE208425T1 (de) | 2001-11-15 |
Family
ID=24396174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97907894T ATE208425T1 (de) | 1996-02-12 | 1997-02-12 | Kodierende sequenzen des menschlichen brca1-gens |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US5654155A (de) |
| EP (3) | EP0820526B1 (de) |
| JP (2) | JPH11503924A (de) |
| AT (1) | ATE208425T1 (de) |
| AU (1) | AU1977897A (de) |
| BR (1) | BR9702080A (de) |
| CA (1) | CA2218251C (de) |
| DE (1) | DE69707985T2 (de) |
| DK (1) | DK0820526T3 (de) |
| ES (1) | ES2170366T3 (de) |
| IL (1) | IL121926A (de) |
| IS (1) | IS4587A (de) |
| PT (1) | PT820526E (de) |
| WO (1) | WO1997029213A1 (de) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6403303B1 (en) * | 1996-05-14 | 2002-06-11 | Visible Genetics Inc. | Method and reagents for testing for mutations in the BRCA1 gene |
| US5747282A (en) * | 1994-08-12 | 1998-05-05 | Myraid Genetics, Inc. | 17Q-linked breast and ovarian cancer susceptibility gene |
| US6083698A (en) * | 1995-09-25 | 2000-07-04 | Oncormed, Inc. | Cancer susceptibility mutations of BRCA1 |
| US6130322A (en) * | 1996-02-12 | 2000-10-10 | Gene Logic, Inc. | Coding sequences of the human BRCA1 gene |
| US6951721B2 (en) * | 1996-02-12 | 2005-10-04 | Gene Logic Inc. | Method for determining the haplotype of a human BRCA1 gene |
| US20030022184A1 (en) * | 1996-02-12 | 2003-01-30 | Oncormed. Inc. | Coding sequences of the human BRCA1 gene |
| US6838256B2 (en) | 1996-02-12 | 2005-01-04 | Gene Logic Inc. | Coding sequences of the human BRCA1 gene |
| US5654155A (en) * | 1996-02-12 | 1997-08-05 | Oncormed, Inc. | Consensus sequence of the human BRCA1 gene |
| US5891857A (en) * | 1996-02-20 | 1999-04-06 | Vanderbilt University | Characterized BRCA1 and BRCA2 proteins and screening and therapeutic methods based on characterized BRCA1 and BRCA2 proteins |
| US5912127A (en) * | 1996-02-29 | 1999-06-15 | Mcgill University | Method and kit for evaluating risk of ovarian cancer in carriers of a BRCA1 mutation |
| EP0918788A4 (de) * | 1996-07-08 | 2002-02-13 | Univ Texas | Brca1 zusammensetzungen und methoden zur diagnose und behandlung von brustkrebs |
| WO1998012327A2 (en) * | 1996-09-20 | 1998-03-26 | Board Of Regents, The University Of Texas System | Compositions and methods comprising bard1 and other brca1 binding proteins |
| WO1998018966A1 (en) * | 1996-10-31 | 1998-05-07 | Jennifer Lescallett | Primers for amplification of brca1 |
| US6048689A (en) * | 1997-03-28 | 2000-04-11 | Gene Logic, Inc. | Method for identifying variations in polynucleotide sequences |
| EP0878552A1 (de) * | 1997-05-13 | 1998-11-18 | Erasmus Universiteit Rotterdam | Molekularer Nachweis von chromosomalen Veränderungen |
| WO1999006598A2 (en) * | 1997-08-04 | 1999-02-11 | Oncormed, Inc. | Determining common functional alleles in a population and uses therefor |
| US20090269814A1 (en) * | 1998-05-22 | 2009-10-29 | Murphy Patricia D | Method of Analyzing a BRCA2 Gene in a Human Subject |
| WO1999015704A1 (en) * | 1997-09-23 | 1999-04-01 | Oncormed, Inc. | Genetic panel assay for susceptibility mutations in breast and ovarian cancer |
| US6492109B1 (en) | 1997-09-23 | 2002-12-10 | Gene Logic, Inc. | Susceptibility mutation 6495delGC of BRCA2 |
| US6030832A (en) | 1997-11-21 | 2000-02-29 | Myriad Genetics, Inc. | Carboxy-terminal BRCA1 interacting protein |
| US6177410B1 (en) | 1997-12-05 | 2001-01-23 | Vanderbilt University | Therapeutic methods for prostate cancer |
| US6897018B1 (en) * | 1998-02-25 | 2005-05-24 | The United States Of America As Represented By The Department Of Health And Human Services | DLC-1 gene deleted in cancers |
| WO1999057309A1 (en) * | 1998-05-04 | 1999-11-11 | Dako A/S | Method and probes for the detection of chromosome aberrations |
| US6686163B2 (en) * | 1998-05-06 | 2004-02-03 | Gene Logic Inc. | Coding sequence haplotype of the human BRCA1 gene |
| IL140701A0 (en) | 1998-07-13 | 2002-02-10 | Univ Texas | Cancer treatment methods using antibodies to aminophospholipids |
| SI1107795T1 (en) | 1998-09-04 | 2003-06-30 | The Regents Of The University Of Michigan | Thiomolybdate associated with at least one carbohydrate, and its use for preventing or treating diseases characterized by aberrant vascularization, such as cancer, wet type macular degeneration, rheumatoid arthritis |
| US20030180789A1 (en) * | 1998-12-30 | 2003-09-25 | Dale Roderic M.K. | Arrays with modified oligonucleotide and polynucleotide compositions |
| US6087112A (en) * | 1998-12-30 | 2000-07-11 | Oligos Etc. Inc. | Arrays with modified oligonucleotide and polynucleotide compositions |
| WO2003104398A2 (en) * | 2002-06-06 | 2003-12-18 | Johns Hopkins University School Of Medicine | Allelic variation in human gene expression |
| EP2283868B1 (de) | 2002-07-15 | 2016-03-30 | Board of Regents, The University of Texas System | Peptide mit Bindung an Phosphatidylethanolamine und ihre Verwendung bei der Behandlung von Virusinfektionen und Krebs |
| TWI304321B (en) | 2002-12-27 | 2008-12-11 | Toray Industries | Layered products, electromagnetic wave shielding molded articles and method for production thereof |
| US8431396B2 (en) | 2003-03-21 | 2013-04-30 | The Cleveland Clinic Foundation | Anti-angiogenic peptides |
| WO2005061728A1 (en) * | 2003-12-16 | 2005-07-07 | Institut Curie | Methods and compositions for assaying mutations in nucleic acids |
| CA3031283A1 (en) | 2004-01-22 | 2005-08-04 | University Of Miami | Topical co-enzyme q10 formulations and methods of use |
| MX2010005104A (es) | 2007-11-09 | 2010-08-04 | Peregrine Pharmaceuticals Inc | Composiciones de anticuerpo anti-factor de crecimiento endotelial vascular y metodos. |
| ES2574137T3 (es) * | 2008-09-03 | 2016-06-15 | Quantumdx Group Limited | Estrategias y métodos de detección de ácidos nucleicos mediante biosensores |
| WO2010059233A2 (en) | 2008-11-21 | 2010-05-27 | Morehouse School Of Medicine | Application for letters patent |
| WO2013064895A1 (en) | 2011-10-31 | 2013-05-10 | Genomic Vision | Methods for the detection, visualization and high resolution physical mapping of genomic rearrangements in breast and ovarian cancer genes and loci brca1 and brca2 using genomic morse code in conjunction with molecular combing |
| WO2014140788A1 (en) | 2013-03-15 | 2014-09-18 | Genomic Vision | Methods for the detection of sequence amplification in the brca1 locus |
| JP6445469B2 (ja) | 2013-03-15 | 2019-01-09 | ゲノミク ビジョン | 再編成したゲノム配列の分断点を検出するための方法 |
| EP3839974B9 (de) | 2019-12-20 | 2023-05-03 | Dynamic Code AB | Verfahren zur analyse der wahrscheinlichkeit von krankheiten |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4704362A (en) | 1977-11-08 | 1987-11-03 | Genentech, Inc. | Recombinant cloning vehicle microbial polypeptide expression |
| US5221619A (en) | 1977-11-08 | 1993-06-22 | Genentech, Inc. | Method and means for microbial polypeptide expression |
| US5583013A (en) | 1977-11-08 | 1996-12-10 | Genentech, Inc. | Method and means for microbial polypeptide expression |
| US4458066A (en) * | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US5593840A (en) | 1993-01-27 | 1997-01-14 | Oncor, Inc. | Amplification of nucleic acid sequences |
| WO1995019369A1 (en) * | 1994-01-14 | 1995-07-20 | Vanderbilt University | Method for detection and treatment of breast cancer |
| CA2196795C (en) * | 1994-08-12 | 2001-04-03 | Mark H. Skolnick | Method for diagnosing a predisposition for breast and ovarian cancer |
| US5693473A (en) * | 1994-08-12 | 1997-12-02 | Myriad Genetics, Inc. | Linked breast and ovarian cancer susceptibility gene |
| CN1172502A (zh) * | 1994-08-12 | 1998-02-04 | 亿万遗传股份有限公司 | 17q连锁的乳房癌和卵巢癌易患性基因的体内突变和多态性 |
| US5654155A (en) * | 1996-02-12 | 1997-08-05 | Oncormed, Inc. | Consensus sequence of the human BRCA1 gene |
-
1996
- 1996-02-12 US US08/598,591 patent/US5654155A/en not_active Expired - Lifetime
-
1997
- 1997-02-12 DK DK97907894T patent/DK0820526T3/da active
- 1997-02-12 EP EP97907894A patent/EP0820526B1/de not_active Expired - Lifetime
- 1997-02-12 CA CA2218251A patent/CA2218251C/en not_active Expired - Fee Related
- 1997-02-12 AT AT97907894T patent/ATE208425T1/de active
- 1997-02-12 WO PCT/US1997/003038 patent/WO1997029213A1/en not_active Ceased
- 1997-02-12 US US08/798,691 patent/US5750400A/en not_active Expired - Lifetime
- 1997-02-12 JP JP9528770A patent/JPH11503924A/ja not_active Withdrawn
- 1997-02-12 IL IL121926A patent/IL121926A/en not_active IP Right Cessation
- 1997-02-12 BR BR9702080-0A patent/BR9702080A/pt not_active Application Discontinuation
- 1997-02-12 AU AU19778/97A patent/AU1977897A/en not_active Abandoned
- 1997-02-12 EP EP10184120A patent/EP2351854A1/de not_active Withdrawn
- 1997-02-12 ES ES97907894T patent/ES2170366T3/es not_active Expired - Lifetime
- 1997-02-12 PT PT97907894T patent/PT820526E/pt unknown
- 1997-02-12 EP EP01107300A patent/EP1126034A3/de not_active Withdrawn
- 1997-02-12 DE DE69707985T patent/DE69707985T2/de not_active Expired - Lifetime
- 1997-10-10 IS IS4587A patent/IS4587A/is unknown
-
2011
- 2011-10-14 JP JP2011227253A patent/JP2012090627A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL121926A (en) | 2006-08-01 |
| CA2218251A1 (en) | 1997-08-14 |
| PT820526E (pt) | 2002-05-31 |
| EP1126034A3 (de) | 2001-08-29 |
| EP1126034A2 (de) | 2001-08-22 |
| ES2170366T3 (es) | 2002-08-01 |
| WO1997029213A1 (en) | 1997-08-14 |
| US5654155A (en) | 1997-08-05 |
| CA2218251C (en) | 2010-10-19 |
| DE69707985D1 (de) | 2001-12-13 |
| EP0820526A4 (de) | 1998-07-08 |
| EP0820526B1 (de) | 2001-11-07 |
| US5750400A (en) | 1998-05-12 |
| JP2012090627A (ja) | 2012-05-17 |
| EP0820526A1 (de) | 1998-01-28 |
| DK0820526T3 (da) | 2002-03-04 |
| JPH11503924A (ja) | 1999-04-06 |
| DE69707985T2 (de) | 2002-10-31 |
| IL121926A0 (en) | 1998-03-10 |
| EP2351854A1 (de) | 2011-08-03 |
| AU1977897A (en) | 1997-08-28 |
| BR9702080A (pt) | 1999-12-28 |
| IS4587A (is) | 1997-10-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EEIH | Change in the person of patent owner |