ATE208505T1 - Verfahren und reagenz zur überwachung des blutspiegels von antiplättchen-verbindungen - Google Patents

Verfahren und reagenz zur überwachung des blutspiegels von antiplättchen-verbindungen

Info

Publication number
ATE208505T1
ATE208505T1 AT97924591T AT97924591T ATE208505T1 AT E208505 T1 ATE208505 T1 AT E208505T1 AT 97924591 T AT97924591 T AT 97924591T AT 97924591 T AT97924591 T AT 97924591T AT E208505 T1 ATE208505 T1 AT E208505T1
Authority
AT
Austria
Prior art keywords
compounds
reagent
antiplatelet
antiplete
blood levels
Prior art date
Application number
AT97924591T
Other languages
English (en)
Inventor
Christopher P Carron
Larry P Feigen
Neal F Haas
Debra M Meyer
Jimmy D Page
Jodi Ann Pegg
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Application granted granted Critical
Publication of ATE208505T1 publication Critical patent/ATE208505T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/808Optical sensing apparatus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT97924591T 1996-05-15 1997-05-12 Verfahren und reagenz zur überwachung des blutspiegels von antiplättchen-verbindungen ATE208505T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1771096P 1996-05-15 1996-05-15
PCT/US1997/007645 WO1997043650A1 (en) 1996-05-15 1997-05-12 Method and reagent for monitoring blood levels of antiplatelet compounds

Publications (1)

Publication Number Publication Date
ATE208505T1 true ATE208505T1 (de) 2001-11-15

Family

ID=21784121

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97924591T ATE208505T1 (de) 1996-05-15 1997-05-12 Verfahren und reagenz zur überwachung des blutspiegels von antiplättchen-verbindungen

Country Status (11)

Country Link
US (1) US6150114A (de)
EP (1) EP0912901B1 (de)
JP (1) JP2000510700A (de)
AT (1) ATE208505T1 (de)
AU (1) AU2997597A (de)
CA (1) CA2253402A1 (de)
DE (1) DE69708102T2 (de)
DK (1) DK0912901T3 (de)
ES (1) ES2166996T3 (de)
PT (1) PT912901E (de)
WO (1) WO1997043650A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6221672B1 (en) * 1996-04-30 2001-04-24 Medtronic, Inc. Method for determining platelet inhibitor response
AU1712700A (en) * 1998-11-18 2000-06-05 G.D. Searle & Co. Restoration of platelet aggregation by antibody administration after gpiib/iiia antagonist treatment
US6972296B2 (en) 1999-05-07 2005-12-06 Encysive Pharmaceuticals Inc. Carboxylic acid derivatives that inhibit the binding of integrins to their receptors
NZ515248A (en) * 1999-05-07 2004-01-30 Texas Biotechnology Corp Heterocyclic substituted carboxylic acid derivatives useful for inhibit the binding of integrins to their receptors
EP1745145A4 (de) * 2004-05-11 2008-03-26 Heptest Lab Inc Zusammensetzung, kit und einstufiges verfahren zur überwachung von verbindungen mit anti-faktor-xa- und/oder anti-faktor-iia-wirkungen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4393040A (en) * 1981-03-24 1983-07-12 Lopapa Institute, Inc. In-vitro diagnostic method for detection of acetylsalicylic acid ingestion
US4871677A (en) * 1985-02-25 1989-10-03 Hemotec, Inc. Method of collecting and analyzing a sample of blood when monitoring heparin therapy
US5182260A (en) * 1989-01-27 1993-01-26 Biogen, Inc. Dna sequences encoding snake venom inhibitors of platelet activation processes for producing those inhibitors and compositions using them
CA2072412A1 (en) * 1991-06-28 1992-12-29 Koichi Kondo Monoclonal antibody, method of production thereof and use thereof
US5239113A (en) * 1991-10-15 1993-08-24 Monsanto Company Substituted β-amino acid derivatives useful as platelet aggregation inhibitors and intermediates thereof
DE69425431T2 (de) * 1993-03-31 2001-02-08 G.D. Searle & Co., Chicago 1-amdinophenyl-pyrrolidone/piperidinone als blutblättchen-aggregations inhibitoren
US5662671A (en) * 1996-07-17 1997-09-02 Embol-X, Inc. Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries

Also Published As

Publication number Publication date
EP0912901B1 (de) 2001-11-07
PT912901E (pt) 2002-04-29
AU2997597A (en) 1997-12-05
WO1997043650A1 (en) 1997-11-20
DE69708102D1 (de) 2001-12-13
CA2253402A1 (en) 1997-11-20
JP2000510700A (ja) 2000-08-22
DE69708102T2 (de) 2002-07-11
DK0912901T3 (da) 2002-02-25
US6150114A (en) 2000-11-21
ES2166996T3 (es) 2002-05-01
EP0912901A1 (de) 1999-05-06

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee