ATE208766T1 - (2-morpholinylmethyl)benzamid-derivate - Google Patents

(2-morpholinylmethyl)benzamid-derivate

Info

Publication number: ATE208766T1
Authority: AT; Austria
Prior art keywords: 6alkyl; hydrogen; alk; amino; 6alkyloxy
Prior art date: 1995-05-23

Application number

AT96916121T

Other languages

English (en)

Inventor

Daele Georges Henri Paul D Van

Den Keybus Frans Maria Alf Van

Marc Gustaaf Celine Verdonck

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-05-23

Filing date

1996-05-15

Publication date

2001-11-15

1996-05-15 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2001-11-15 Application granted granted Critical

2001-11-15 Publication of ATE208766T1 publication Critical patent/ATE208766T1/de

Links

QKWAMNZOEPKQBV-UHFFFAOYSA-N 2-(morpholin-2-ylmethyl)benzamide Chemical class NC(=O)C1=CC=CC=C1CC1OCCNC1 QKWAMNZOEPKQBV-UHFFFAOYSA-N 0.000 title abstract 2
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 6
229910052739 hydrogen Inorganic materials 0.000 abstract 5
239000001257 hydrogen Substances 0.000 abstract 5
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
125000006619 (C1-C6) dialkylamino group Chemical group 0.000 abstract 2
125000001475 halogen functional group Chemical group 0.000 abstract 2
125000000623 heterocyclic group Chemical group 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
125000004845 (C1-C6) alkylsulfonylamino group Chemical group 0.000 abstract 1
-1 C1-6alkyloxy Chemical group 0.000 abstract 1
125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 1
125000003601 C2-C6 alkynyl group Chemical group 0.000 abstract 1
125000000815 N-oxide group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000003247 decreasing effect Effects 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
230000030136 gastric emptying Effects 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT96916121T 1995-05-23 1996-05-15 (2-morpholinylmethyl)benzamid-derivate ATE208766T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP95201350		1995-05-23
PCT/EP1996/002141 WO1996037486A1 (en)	1995-05-23	1996-05-15	(2-morpholinylmethyl)benzamide derivatives

Publications (1)

Publication Number	Publication Date
ATE208766T1 true ATE208766T1 (de)	2001-11-15

Family

ID=8220318

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96916121T ATE208766T1 (de)	1995-05-23	1996-05-15	(2-morpholinylmethyl)benzamid-derivate

Country Status (18)

Country	Link
US (1)	US6100262A (de)
EP (1)	EP0827500B1 (de)
JP (1)	JPH11505815A (de)
KR (1)	KR100446099B1 (de)
AT (1)	ATE208766T1 (de)
AU (1)	AU710037B2 (de)
CA (1)	CA2220140C (de)
DE (1)	DE69617001T2 (de)
DK (1)	DK0827500T3 (de)
ES (1)	ES2167563T3 (de)
IL (1)	IL118379A (de)
MY (1)	MY117938A (de)
NO (1)	NO309900B1 (de)
NZ (1)	NZ309065A (de)
PT (1)	PT827500E (de)
TW (1)	TW505639B (de)
WO (1)	WO1996037486A1 (de)
ZA (1)	ZA964100B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL155093A0 (en)	2000-09-29	2003-10-31	Glaxo Group Ltd	Morpholin-acetamide derivatives for the treatment on inflammatory diseases
UA77515C2 (en) *	2002-04-04	2006-12-15		Diazabicyclo alkane derivatives possessing neuroldnin-nk1 receptor antagonistic activity
TWI423967B (zh) *	2008-02-21	2014-01-21	Dainippon Sumitomo Pharma Co	醯胺衍生物及含有其之醫藥組合物
MD3762368T2 (ro)	2018-03-08	2022-07-31	Incyte Corp	Compuși diol aminopirazină ca inhibitori ai PI3K-Y
US11046658B2 (en)	2018-07-02	2021-06-29	Incyte Corporation	Aminopyrazine derivatives as PI3K-γ inhibitors
CN110938068B (zh) *	2019-11-06	2022-12-23	广东东阳光药业有限公司	N-(吗啉-2-基甲基)酰胺衍生物及其用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CZ284687B6 (cs) *	1986-04-30	1999-02-17	Dainippon Pharmaceutical Co., Ltd.	Substituovaný benzamidový derivát, způsob jeho výroby a farmaceutický prostředek na jeho bázi
EP0774460A1 (de) *	1994-03-30	1997-05-21	Yoshitomi Pharmaceutical Industries, Ltd.	Benzosäurederivate und ihre medizinische verwendung

1996
- 1996-05-15 ES ES96916121T patent/ES2167563T3/es not_active Expired - Lifetime
- 1996-05-15 KR KR1019970707669A patent/KR100446099B1/ko not_active Expired - Fee Related
- 1996-05-15 EP EP96916121A patent/EP0827500B1/de not_active Expired - Lifetime
- 1996-05-15 WO PCT/EP1996/002141 patent/WO1996037486A1/en not_active Ceased
- 1996-05-15 AT AT96916121T patent/ATE208766T1/de not_active IP Right Cessation
- 1996-05-15 NZ NZ309065A patent/NZ309065A/xx unknown
- 1996-05-15 JP JP8535361A patent/JPH11505815A/ja active Pending
- 1996-05-15 DK DK96916121T patent/DK0827500T3/da active
- 1996-05-15 DE DE69617001T patent/DE69617001T2/de not_active Expired - Lifetime
- 1996-05-15 PT PT96916121T patent/PT827500E/pt unknown
- 1996-05-15 CA CA002220140A patent/CA2220140C/en not_active Expired - Lifetime
- 1996-05-15 AU AU58992/96A patent/AU710037B2/en not_active Ceased
- 1996-05-21 MY MYPI96001904A patent/MY117938A/en unknown
- 1996-05-22 IL IL11837996A patent/IL118379A/xx not_active IP Right Cessation
- 1996-05-22 ZA ZA9604100A patent/ZA964100B/xx unknown
- 1996-06-04 TW TW085106627A patent/TW505639B/zh active
1997
- 1997-11-21 NO NO975342A patent/NO309900B1/no unknown
1999
- 1999-09-22 US US09/401,729 patent/US6100262A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ZA964100B (en)	1997-11-24
NO975342L (no)	1997-11-21
DK0827500T3 (da)	2002-02-25
IL118379A (en)	1999-12-31
WO1996037486A1 (en)	1996-11-28
TW505639B (en)	2002-10-11
NZ309065A (en)	1999-06-29
MY117938A (en)	2004-08-30
KR100446099B1 (ko)	2004-11-10
NO975342D0 (no)	1997-11-21
AU5899296A (en)	1996-12-11
DE69617001T2 (de)	2002-07-11
PT827500E (pt)	2002-04-29
CA2220140A1 (en)	1996-11-28
CA2220140C (en)	2008-02-12
NO309900B1 (no)	2001-04-17
DE69617001D1 (de)	2001-12-20
EP0827500A1 (de)	1998-03-11
IL118379A0 (en)	1996-09-12
EP0827500B1 (de)	2001-11-14
US6100262A (en)	2000-08-08
AU710037B2 (en)	1999-09-09
JPH11505815A (ja)	1999-05-25
KR19990008144A (ko)	1999-01-25
ES2167563T3 (es)	2002-05-16

Legal Events

Date	Code	Title	Description
2002-05-15	UEP	Publication of translation of european patent specification
2011-02-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
AP1475A (en)	2005-10-03	Trisubstituted 1, 3, 5-triazine derivatives for treatment of HIV infections.
BG104738A (en)	2001-04-30	Hiv inhibiting pyrimidine derivatives
DK0590919T3 (da)	2000-04-17	Terapeutiske midler mod Parkinsons sygdom
NO920035L (no)	1992-07-01	Trifluormetylketon-derivater, og deres fremstilling og anvendelse
GB1058984A (en)	1967-02-15	Indolyl amides
GB1046506A (en)	1966-10-26	Guanidine compounds and process for their manufacture
IL106387A (en)	1997-04-15	Indole derivatives, their preparation and pharmaceutical compositions containing them
MY132062A (en)	2007-09-28	Apolipoprotein-b synthesis inhibitors
BG104717A (en)	2001-07-31	Water soluble azoles as broad-spectrum antifungals
SE8101464L (sv)	1981-09-11	2-penem-3-karboxylsyraderivat, deras framstellning och anvendning
MY125562A (en)	2006-08-30	Hexahydro-pyrido (4,3-b) indole derivatives as antipsychotic drugs
DE69617001D1 (de)	2001-12-20	(2-morpholinylmethyl)benzamid-derivate
HUP9700955A2 (hu)	1998-03-02	Szubsztituált 2-naftoil-guanidin-származékok, előállításuk, valamint az e vegyületeket tartalmazó gyógyszerkészítmények
IL117980A (en)	2000-02-17	Triazolone derivatives their preparation and pharmaceutical compositions containing them useful for the treatment of hyperlipidemia
NO175097C (no)	1994-08-31	Analogifremgangsmåte for fremstilling av terapeutisk aktive hydrazoner
ES363527A1 (es)	1971-01-01	Procedimiento para la obtencion de derivados de las benza- zocinas.
CA2200579A1 (en)	1996-04-04	Phenyl-oxo-alkyl-(4-piperidinyl)benzoate derivatives as colon motility enhancing agents
MX9702356A (es)	1997-10-31	Derivados de fenil-oxo-alquil-(4-piperidinil)benzoato.
NO20010332L (no)	2001-03-20	Nye derivater av 6-deoksyerytromycin, deres fremstillingsprosess og deres anvendelse som medikamenter
ATE44741T1 (de)	1989-08-15	2-(n-substituierte guanidino)-4heteroarylthiazole als mittel gegen geschwuere.
JO1648B1 (en)	1991-11-27	Nitrogen compounds
GB1013904A (en)	1965-12-22	Piperazinium salts and compositions containing them