ATE209036T1 - Verwendung von imidazo(a,5-a)quinolonen als neuroprotektive arzneimittel - Google Patents

Verwendung von imidazo(a,5-a)quinolonen als neuroprotektive arzneimittel

Info

Publication number: ATE209036T1
Authority: AT; Austria
Prior art keywords: imidazo; quinolones; neuroprotective drugs; conditions; neuroprotective
Prior art date: 1995-06-15

Application number

AT96917855T

Other languages

English (en)

Inventor

Donald B Carter

Original Assignee

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-15

Filing date

1996-06-03

Publication date

2001-12-15

1996-06-03 Application filed by Upjohn Co filed Critical Upjohn Co

2001-12-15 Application granted granted Critical

2001-12-15 Publication of ATE209036T1 publication Critical patent/ATE209036T1/de

Links

239000004090 neuroprotective agent Substances 0.000 title 1
LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical compound C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 title 1
208000012902 Nervous system disease Diseases 0.000 abstract 1
208000025966 Neurological disease Diseases 0.000 abstract 1
230000001684 chronic effect Effects 0.000 abstract 1
OWZFYIIJHLFOIG-UHFFFAOYSA-N imidazo[1,5-a]quinoline Chemical class C1=CC=C2N3C=NC=C3C=CC2=C1 OWZFYIIJHLFOIG-UHFFFAOYSA-N 0.000 abstract 1
230000004770 neurodegeneration Effects 0.000 abstract 1
208000015122 neurodegenerative disease Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Neurology (AREA)
Organic Chemistry (AREA)
Psychology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT96917855T 1995-06-15 1996-06-03 Verwendung von imidazo(a,5-a)quinolonen als neuroprotektive arzneimittel ATE209036T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US24695P	1995-06-15	1995-06-15
PCT/US1996/007952 WO1997000074A1 (en)	1995-06-15	1996-06-03	USE OF IMIDAZO[1,5-a]QUINOLONES AS NEUROPROTECTIVE AGENTS

Publications (1)

Publication Number	Publication Date
ATE209036T1 true ATE209036T1 (de)	2001-12-15

Family

ID=21690598

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96917855T ATE209036T1 (de)	1995-06-15	1996-06-03	Verwendung von imidazo(a,5-a)quinolonen als neuroprotektive arzneimittel

Country Status (10)

Country	Link
US (1)	US5935970A (de)
EP (1)	EP0833638B1 (de)
JP (1)	JP2001518056A (de)
AT (1)	ATE209036T1 (de)
AU (1)	AU6025996A (de)
DE (1)	DE69617237T2 (de)
DK (1)	DK0833638T3 (de)
ES (1)	ES2167569T3 (de)
PT (1)	PT833638E (de)
WO (1)	WO1997000074A1 (de)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3454579A (en) *	1967-08-17	1969-07-08	American Cyanamid Co	Imidazo(1,5-a)quinolin-1-one and thione derivatives
US4350814A (en) *	1979-10-22	1982-09-21	Ici Americas Inc.	Pyrrolo [3,4-c]quinoline compounds
FR2593179B1 (fr) *	1986-01-22	1988-04-01	Synthelabo	Derives d'imidazo(1,2-a)quinoleines, leur preparation et leur application en therapeutique
US5190951A (en) *	1990-10-19	1993-03-02	Ss Pharmaceutical Co., Ltd.	Quinoline derivatives
DK0729469T3 (da) *	1993-11-19	1999-06-14	Upjohn Co	Imidazo[1,5-a]quinoliner til behandling af angst og søvnforstyrrelser
US5580877A (en) *	1994-04-25	1996-12-03	Merck Sharp & Dohme Ltd.	Pyrazolo-quinoline derivatives for treating cerebral ischemia

1996
- 1996-06-03 AT AT96917855T patent/ATE209036T1/de not_active IP Right Cessation
- 1996-06-03 PT PT96917855T patent/PT833638E/pt unknown
- 1996-06-03 AU AU60259/96A patent/AU6025996A/en not_active Abandoned
- 1996-06-03 EP EP96917855A patent/EP0833638B1/de not_active Expired - Lifetime
- 1996-06-03 WO PCT/US1996/007952 patent/WO1997000074A1/en not_active Ceased
- 1996-06-03 US US08/657,119 patent/US5935970A/en not_active Expired - Fee Related
- 1996-06-03 JP JP50309097A patent/JP2001518056A/ja not_active Withdrawn
- 1996-06-03 ES ES96917855T patent/ES2167569T3/es not_active Expired - Lifetime
- 1996-06-03 DK DK96917855T patent/DK0833638T3/da active
- 1996-06-03 DE DE69617237T patent/DE69617237T2/de not_active Expired - Fee Related

Also Published As

Publication number	Publication date
WO1997000074A1 (en)	1997-01-03
EP0833638A1 (de)	1998-04-08
DE69617237T2 (de)	2002-06-27
AU6025996A (en)	1997-01-15
DK0833638T3 (da)	2002-05-21
PT833638E (pt)	2002-05-31
US5935970A (en)	1999-08-10
ES2167569T3 (es)	2002-05-16
DE69617237D1 (de)	2002-01-03
JP2001518056A (ja)	2001-10-09
EP0833638B1 (de)	2001-11-21

Legal Events

Date	Code	Title	Description
2002-03-15	UEP	Publication of translation of european patent specification
2006-03-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DK0877734T3 (da)	2000-11-20	Quinolin- og quinazolinforbindelser, der er egnede i terapi
DE69626539D1 (de)	2003-04-10	topische Verwendung von Vitamin D zur Behandlung von Augenerkrankungen
TR199600265A1 (tr)	1997-03-21	Kinazolin türevleri.
DE69618959D1 (de)	2002-03-14	Pyrimidone und ihre verwendug als fungizide
ATE213245T1 (de)	2002-02-15	Triazolo(4,5-d)pyrimidinyl-derivate und ihre verwendung als medikamente
FI901148A7 (fi)	1990-09-09	Tetrahydrokinoliinijohdannaisia, jotka ovat käyttökelpoisia hermojen rappeutumistilojen hoidossa
AU3190593A (en)	1993-07-29	Molecules for iontophoretic delivery
DE69614149D1 (de)	2001-08-30	Chinolinderivate als antimalariamittel
DE69609864D1 (de)	2000-09-21	Steroidnitritesterderivate und ihre verwendung als entzündungshemmende medikamente
ZA968990B (en)	1998-04-28	Pharmaceutical agents for the treatment of acute and chronic inflammatory diseases.
AU3524995A (en)	1996-04-19	Method for treatment of cancers by regulating the activity of ras proteins
MY110149A (en)	1998-02-28	Compounds for the treatment of neurodegenerative disorders
NO892505L (no)	1989-12-21	Behandling av vandige dispersjoner.
LV11940A (lv)	1998-01-20	Melatonina pielietojums personu arstesanai kuras cies no zalu atkaribas
NO981822L (no)	1998-04-23	Anvendelse av proteinet GAX for behandling av cancer
EE03437B1 (et)	2001-06-15	Benseenamiidid neurodegeneratiivsete haiguste ravimiseks
ZA966842B (en)	1998-02-16	Transdermal administration of vorozole.
AU668241B2 (en)	1996-04-26	Condensed heterocyclic compounds, their production and use
DE69616598D1 (de)	2001-12-06	Verwendung von tricyclischen 1,4-dihydro-1,4-dioxo-1h-naphalen derivaten, neue verbindungen und ihre therapeutische verwendung
AU7059296A (en)	1997-05-15	NK-1 receptor antagonists for the treatment of cancer
DE69514315D1 (de)	2000-02-10	AZABICYCLOALKYLDERIVATE VON IMIDAZO[1,5-a]INDOL-3-ONE ALS 5HT3 ANTAGONISTEN
ATE209036T1 (de)	2001-12-15	Verwendung von imidazo(a,5-a)quinolonen als neuroprotektive arzneimittel
AU4585993A (en)	1994-03-15	Use of angiotensin ii antagonists for the treatment of hyperlipidaeme
RU95122486A (ru)	1998-01-27	Средство для лечения тикозных гиперкинезов
DE59604915D1 (de)	2000-05-11	Entschwefelungsmittel zur koinjektions-behandlung von roheisenschmelzen