ATE209197T1 - Imidazolidinon-derivate, deren säure- additionssalze und mittel gegen senile demenz - Google Patents
Imidazolidinon-derivate, deren säure- additionssalze und mittel gegen senile demenzInfo
- Publication number
- ATE209197T1 ATE209197T1 AT94926388T AT94926388T ATE209197T1 AT E209197 T1 ATE209197 T1 AT E209197T1 AT 94926388 T AT94926388 T AT 94926388T AT 94926388 T AT94926388 T AT 94926388T AT E209197 T1 ATE209197 T1 AT E209197T1
- Authority
- AT
- Austria
- Prior art keywords
- denotes
- acid addition
- addition salts
- senile dementia
- lower alkyl
- Prior art date
Links
- 208000024827 Alzheimer disease Diseases 0.000 title abstract 2
- 206010039966 Senile dementia Diseases 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title abstract 2
- 150000008624 imidazolidinones Chemical class 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- UQOFGTXDASPNLL-XHNCKOQMSA-N Muscarine Chemical compound C[C@@H]1O[C@H](C[N+](C)(C)C)C[C@H]1O UQOFGTXDASPNLL-XHNCKOQMSA-N 0.000 abstract 1
- 230000001713 cholinergic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Psychiatry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25498593 | 1993-09-17 | ||
| JP24193194A JP3916092B2 (ja) | 1993-09-17 | 1994-09-09 | イミダゾリジノン誘導体とその酸付加塩及び老年性痴呆症の治療薬 |
| PCT/JP1994/001506 WO1995007906A1 (en) | 1993-09-17 | 1994-09-12 | Imidazolidinone derivative, acid-addition salt thereof, and remedy for senile dementia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE209197T1 true ATE209197T1 (de) | 2001-12-15 |
Family
ID=26535518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94926388T ATE209197T1 (de) | 1993-09-17 | 1994-09-12 | Imidazolidinon-derivate, deren säure- additionssalze und mittel gegen senile demenz |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5789425A (de) |
| EP (1) | EP0719773B1 (de) |
| JP (1) | JP3916092B2 (de) |
| KR (1) | KR100364340B1 (de) |
| CN (1) | CN1043990C (de) |
| AT (1) | ATE209197T1 (de) |
| AU (1) | AU679115B2 (de) |
| CA (1) | CA2172163A1 (de) |
| DE (1) | DE69429185D1 (de) |
| HU (1) | HU218570B (de) |
| WO (1) | WO1995007906A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6159990A (en) | 1997-06-18 | 2000-12-12 | Synaptic Pharmaceutical Corporation | Oxazolidinones as α1A receptor antagonists |
| CA2457647A1 (en) * | 2001-10-02 | 2003-04-10 | Acadia Pharmaceuticals, Inc. | Benzimidazolidinone derivatives as muscarinic agents |
| US6951849B2 (en) * | 2001-10-02 | 2005-10-04 | Acadia Pharmaceuticals Inc. | Benzimidazolidinone derivatives as muscarinic agents |
| US7199844B2 (en) * | 2002-05-28 | 2007-04-03 | Rfstream Corporation | Quadratic nyquist slope filter |
| MX2010014572A (es) | 2008-06-27 | 2011-03-24 | Novartis Ag | Compuestos organicos. |
| AU2013206248B2 (en) * | 2008-06-27 | 2016-06-23 | Xenon Pharmaceuticals Inc. | Organic compounds |
| UY32730A (es) * | 2009-06-26 | 2011-01-31 | Novartis Ag | Inhibidores de cyp17 |
| MX359399B (es) | 2011-04-28 | 2018-09-27 | Novartis Ag | Inhibidores de 17alfa-hidroxilasa/c17-20-liasa. |
| EP3628315A1 (de) | 2018-09-28 | 2020-04-01 | Université de Caen Normandie | Kombination aus acetylcholinesterase-inhibitor und 5-ht4-rezeptoragonist als neuroprotektives mittel zur behandlung von neurodegenerativen krankheiten |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH590267A5 (de) * | 1972-10-04 | 1977-07-29 | Ciba Geigy Ag | |
| ZA76475B (en) * | 1975-03-10 | 1977-08-31 | Ciba Geigy Ag | Indolyalkylpiperidines |
| US4329348A (en) * | 1979-02-26 | 1982-05-11 | Ciba-Geigy Corporation | N-Oxacyclic-alkylpiperidines as psychostimulants |
| JPS6133172A (ja) * | 1984-07-24 | 1986-02-17 | Kotobuki Seiyaku Kk | １，３−置換−２−イミダゾリジノン誘導体，胃腸運動亢進剤及びその製造方法 |
| US4600430A (en) * | 1985-02-22 | 1986-07-15 | Eli Lilly And Company | Pyridinylimidazolidinone compounds |
| FI90869C (fi) * | 1986-11-14 | 1994-04-11 | Tanabe Seiyaku Co | Menetelmä lääkeaineena käyttökelpoisten imidatsolidinonijohdannaisten valmistamiseksi |
| SE8904298D0 (sv) * | 1989-12-21 | 1989-12-21 | Astra Ab | New compounds |
| GB9106571D0 (en) * | 1991-03-27 | 1991-05-15 | Erba Carlo Spa | Derivatives of substituted imidazol-2-one and process for their preparation |
| US5300515A (en) * | 1991-01-31 | 1994-04-05 | Kyorin Pharmaceutical Co., Ltd. | Carbamic acid derivatives and method for preparing the same |
-
1994
- 1994-09-09 JP JP24193194A patent/JP3916092B2/ja not_active Expired - Fee Related
- 1994-09-12 EP EP94926388A patent/EP0719773B1/de not_active Expired - Lifetime
- 1994-09-12 AU AU76244/94A patent/AU679115B2/en not_active Ceased
- 1994-09-12 DE DE69429185T patent/DE69429185D1/de not_active Expired - Lifetime
- 1994-09-12 US US08/612,829 patent/US5789425A/en not_active Expired - Fee Related
- 1994-09-12 WO PCT/JP1994/001506 patent/WO1995007906A1/ja not_active Ceased
- 1994-09-12 AT AT94926388T patent/ATE209197T1/de not_active IP Right Cessation
- 1994-09-12 CN CN94194122A patent/CN1043990C/zh not_active Expired - Fee Related
- 1994-09-12 KR KR1019960701381A patent/KR100364340B1/ko not_active Expired - Fee Related
- 1994-09-12 CA CA002172163A patent/CA2172163A1/en not_active Abandoned
- 1994-09-12 HU HU9700621A patent/HU218570B/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR100364340B1 (ko) | 2005-09-26 |
| KR960704877A (ko) | 1996-10-09 |
| DE69429185D1 (de) | 2002-01-03 |
| AU7624494A (en) | 1995-04-03 |
| EP0719773A1 (de) | 1996-07-03 |
| AU679115B2 (en) | 1997-06-19 |
| EP0719773A4 (de) | 1997-04-02 |
| EP0719773B1 (de) | 2001-11-21 |
| CA2172163A1 (en) | 1995-03-23 |
| WO1995007906A1 (en) | 1995-03-23 |
| US5789425A (en) | 1998-08-04 |
| CN1043990C (zh) | 1999-07-07 |
| JP3916092B2 (ja) | 2007-05-16 |
| HUT75647A (en) | 1997-05-28 |
| JPH07233162A (ja) | 1995-09-05 |
| HU9600621D0 (en) | 1996-05-28 |
| CN1135215A (zh) | 1996-11-06 |
| HU218570B (hu) | 2000-10-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |