ATE209643T1 - Heterocyclische verbindungen zur schmerzbehandlung und deren verwendung - Google Patents

Heterocyclische verbindungen zur schmerzbehandlung und deren verwendung

Info

Publication number
ATE209643T1
ATE209643T1 AT96921855T AT96921855T ATE209643T1 AT E209643 T1 ATE209643 T1 AT E209643T1 AT 96921855 T AT96921855 T AT 96921855T AT 96921855 T AT96921855 T AT 96921855T AT E209643 T1 ATE209643 T1 AT E209643T1
Authority
AT
Austria
Prior art keywords
alkyl
pct
independently
heteroatom
sec
Prior art date
Application number
AT96921855T
Other languages
English (en)
Inventor
John Dimaio
Dilip M Dixit
Original Assignee
Shire Biochem Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shire Biochem Inc filed Critical Shire Biochem Inc
Application granted granted Critical
Publication of ATE209643T1 publication Critical patent/ATE209643T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/42Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/44Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton bound to carbon atoms of the same ring or condensed ring system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D225/00Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/04Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D225/08Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D313/00Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/16Eight-membered rings
    • C07D313/20Eight-membered rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D337/00Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/16Eight-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT96921855T 1995-07-14 1996-07-12 Heterocyclische verbindungen zur schmerzbehandlung und deren verwendung ATE209643T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9514417.6A GB9514417D0 (en) 1995-07-14 1995-07-14 Novel heterocyclic compounds for the treatment of pain and use thereof
PCT/CA1996/000467 WO1997003978A1 (en) 1995-07-14 1996-07-12 Novel heterocyclic compounds for the treatment of pain and use thereof

Publications (1)

Publication Number Publication Date
ATE209643T1 true ATE209643T1 (de) 2001-12-15

Family

ID=10777657

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96921855T ATE209643T1 (de) 1995-07-14 1996-07-12 Heterocyclische verbindungen zur schmerzbehandlung und deren verwendung

Country Status (17)

Country Link
US (1) US6054474A (de)
EP (1) EP0850234B1 (de)
JP (1) JPH11509211A (de)
CN (1) CN1196053A (de)
AT (1) ATE209643T1 (de)
AU (1) AU708504B2 (de)
BR (1) BR9609548A (de)
CA (1) CA2223646A1 (de)
DE (1) DE69617444T2 (de)
EA (1) EA001185B1 (de)
ES (1) ES2167577T3 (de)
FI (1) FI974609L (de)
GB (1) GB9514417D0 (de)
HU (1) HUP9900350A3 (de)
NO (1) NO980144D0 (de)
NZ (1) NZ311612A (de)
WO (1) WO1997003978A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10153345A1 (de) * 2001-10-29 2003-05-08 Gruenenthal Gmbh Substituierte 1H-Chinoxalin-2-on-Verbindungen und substituierte 4-Aryl- und 4-Heteroarylcyclohexan-Verbindungen
US6881829B2 (en) * 2002-04-26 2005-04-19 Chimeracom, L.L.C. Chimeric hybrid analgesics
CN108210933B (zh) * 2016-12-22 2021-05-04 北京键凯科技股份有限公司 一种地佐辛与聚乙二醇的结合物
WO2020156522A1 (zh) * 2019-02-02 2020-08-06 扬子江药业集团有限公司 地佐辛衍生物及其医药用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3836670A (en) * 1971-11-19 1974-09-17 American Home Prod Benzobicycloalkane amines for inducing analgesia
US5214156A (en) * 1988-03-25 1993-05-25 The Upjohn Company Therapeutically useful tetralin derivatives
IL114715A (en) * 1989-02-27 1997-01-10 Lilly Co Eli Intermediate compounds for ring-substituted 2-amino-1, 2, 3, 4-tetrahydronaphthalenes and 3-aminochromanes

Also Published As

Publication number Publication date
HUP9900350A3 (en) 1999-11-29
NO980144L (no) 1998-01-13
AU708504B2 (en) 1999-08-05
GB9514417D0 (en) 1995-09-13
AU6296896A (en) 1997-02-18
NZ311612A (en) 1999-05-28
CN1196053A (zh) 1998-10-14
WO1997003978A1 (en) 1997-02-06
DE69617444D1 (de) 2002-01-10
ES2167577T3 (es) 2002-05-16
HUP9900350A2 (hu) 1999-06-28
JPH11509211A (ja) 1999-08-17
FI974609A7 (fi) 1998-01-14
FI974609A0 (fi) 1997-12-23
BR9609548A (pt) 1999-03-02
EA199800062A1 (ru) 1998-08-27
EP0850234B1 (de) 2001-11-28
FI974609L (fi) 1998-01-14
EA001185B1 (ru) 2000-12-25
NO980144D0 (no) 1998-01-13
US6054474A (en) 2000-04-25
DE69617444T2 (de) 2002-08-01
CA2223646A1 (en) 1997-02-06
EP0850234A1 (de) 1998-07-01

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties