ATE210117T1 - Indolderivate als melatoninanaloge - Google Patents

Indolderivate als melatoninanaloge

Info

Publication number: ATE210117T1
Authority: AT; Austria
Prior art keywords: indole derivatives; melatonin analogues; melatonin; analogues; indole
Prior art date: 1995-09-18

Application number

AT96931862T

Other languages

English (en)

Inventor

Jean-Bernard Fourtillan

Marianne Fourtillan

Jean-Claude Jacquesy

Marie-Paule Jouannetaud

Bruno Violeau

Omar Karam

Original Assignee

Cemaf

Besins Iscovesco Sa Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-18

Filing date

1996-09-17

Publication date

2001-12-15

1996-09-17 Application filed by Cemaf, Besins Iscovesco Sa Lab filed Critical Cemaf

2001-12-15 Application granted granted Critical

2001-12-15 Publication of ATE210117T1 publication Critical patent/ATE210117T1/de

Links

SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical class C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title 1
229940054051 antipsychotic indole derivative Drugs 0.000 title 1
DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical class COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
- A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Dermatology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Birds (AREA)
Epidemiology (AREA)
Anesthesiology (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Cosmetics (AREA)

AT96931862T 1995-09-18 1996-09-17 Indolderivate als melatoninanaloge ATE210117T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9510900A FR2738818B1 (fr)	1995-09-18	1995-09-18	Nouveaux derives d'oxydation d'indolylalkylamines, et leur utilisation a titre de medicament
PCT/FR1996/001444 WO1997011056A1 (fr)	1995-09-18	1996-09-17	Derives d'indole comme analogues melatonergiques

Publications (1)

Publication Number	Publication Date
ATE210117T1 true ATE210117T1 (de)	2001-12-15

Family

ID=9482641

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96931862T ATE210117T1 (de)	1995-09-18	1996-09-17	Indolderivate als melatoninanaloge

Country Status (13)

Country	Link
US (1)	US6066663A (de)
EP (1)	EP0851856B1 (de)
JP (1)	JP3513876B2 (de)
AR (1)	AR005865A1 (de)
AT (1)	ATE210117T1 (de)
AU (1)	AU7088396A (de)
DE (1)	DE69617712T2 (de)
DK (1)	DK0851856T3 (de)
ES (1)	ES2169264T3 (de)
FR (1)	FR2738818B1 (de)
PT (1)	PT851856E (de)
WO (1)	WO1997011056A1 (de)
ZA (1)	ZA967870B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2002070478A1 (en)	2001-03-06	2002-09-12	Astrazeneca Ab	Indolone derivatives having vascular-damaging activity
TW200508197A (en) *	2003-03-31	2005-03-01	Ucb Sa	Indolone-acetamide derivatives, processes for preparing them and their uses
FR2857011B1 (fr) *	2003-07-04	2005-09-16	Servier Lab	Nouveaux derives du benzothiophene 2-thiosubstitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
BR102016024814A2 (pt)	2016-10-24	2018-05-08	Aché Laboratórios Farmacêuticos S.A.	composto, processo de obtenção do composto, composição farmacêutica, uso do composto e método de tratamento de desordens psiquiátricas e/ou distúrbios do sono

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2680366B1 (fr) *	1991-08-13	1995-01-20	Adir	Nouveaux derives d'arylethylamines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
WO1994003427A1 (en) *	1992-08-06	1994-02-17	Warner-Lambert Company	2-thioindoles (selenoindoles) and related disulfides (selenides) which inhibit protein tyrosine kinases and which have antitumor properties
JPH09511514A (ja) *	1994-04-07	1997-11-18	セ・エ・エム・ア・エフ	新規メラトニン作用性アゴニストのスピロ［インドールピロリジン］誘導体とその製造方法および医薬品としての用途
FR2737725B1 (fr) *	1995-08-08	1997-10-31	Valentonine	Nouveaux derives acyles de la melatonine et d'analogues melatoninergiques, leur procede de preparation et leur utilisation en tant que medicament

1995
- 1995-09-18 FR FR9510900A patent/FR2738818B1/fr not_active Expired - Fee Related
1996
- 1996-09-17 AT AT96931862T patent/ATE210117T1/de not_active IP Right Cessation
- 1996-09-17 DK DK96931862T patent/DK0851856T3/da active
- 1996-09-17 PT PT96931862T patent/PT851856E/pt unknown
- 1996-09-17 JP JP51243297A patent/JP3513876B2/ja not_active Expired - Fee Related
- 1996-09-17 ES ES96931862T patent/ES2169264T3/es not_active Expired - Lifetime
- 1996-09-17 US US09/043,301 patent/US6066663A/en not_active Expired - Fee Related
- 1996-09-17 DE DE69617712T patent/DE69617712T2/de not_active Expired - Lifetime
- 1996-09-17 EP EP96931862A patent/EP0851856B1/de not_active Expired - Lifetime
- 1996-09-17 WO PCT/FR1996/001444 patent/WO1997011056A1/fr not_active Ceased
- 1996-09-17 AU AU70883/96A patent/AU7088396A/en not_active Abandoned
- 1996-09-18 ZA ZA967870A patent/ZA967870B/xx unknown
- 1996-09-18 AR ARP960104398A patent/AR005865A1/es active IP Right Grant

Also Published As

Publication number	Publication date
AU7088396A (en)	1997-04-09
EP0851856A1 (de)	1998-07-08
FR2738818A1 (fr)	1997-03-21
EP0851856B1 (de)	2001-12-05
ES2169264T3 (es)	2002-07-01
ZA967870B (en)	1997-04-07
JPH11512450A (ja)	1999-10-26
JP3513876B2 (ja)	2004-03-31
DK0851856T3 (da)	2002-04-02
PT851856E (pt)	2002-05-31
FR2738818B1 (fr)	1997-12-05
US6066663A (en)	2000-05-23
AR005865A1 (es)	1999-07-21
DE69617712T2 (de)	2004-05-06
DE69617712D1 (de)	2002-01-17
WO1997011056A1 (fr)	1997-03-27

Legal Events

Date

Code

Title

Description

2003-03-15

UEP

Publication of translation of european patent specification

Ref document number: 0851856

Country of ref document: EP

2011-06-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE69613369D1 (de)	2001-07-19	Chinazolin derivate
DE69613367D1 (de)	2001-07-19	Chinazolin derivate
DE69723446D1 (de)	2003-08-14	Oxindole derivate
DK43193A (da)	1993-10-17	Indolderivater
DE69522717D1 (de)	2001-10-18	Chinazolinderivate
DE69611361D1 (de)	2001-02-01	Chinazolin-derivate
DE69610698D1 (de)	2000-11-23	Chinazolin-derivate
DE69605430D1 (de)	2000-01-05	Chinolin-2-on derivate als serotonin antagonisten
ATE149163T1 (de)	1997-03-15	Indolin derivate als 5ht2c antagonisten
NO961475L (no)	1996-04-12	Indol-derivater
FI972275L (fi)	1997-05-29	Indolijohdannainen
ATE199150T1 (de)	2001-02-15	Diphenylmethylenpiperidin-derivate
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DE69601527D1 (de)	1999-03-25	Pyrrolylbenzimidazol-Derivate
ATA100695A (de)	1998-03-15	Prothrombin-derivate
DK0747346T3 (da)	2000-06-05	N-acyl-2-arylcyclopropylmethylaminderivater som melatonerge midler
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