ATE211930T1 - Verfahren zur herstellung von verkalkungsbeständigem bioprosthetischem gewebe - Google Patents

Verfahren zur herstellung von verkalkungsbeständigem bioprosthetischem gewebe

Info

Publication number
ATE211930T1
ATE211930T1 AT94931415T AT94931415T ATE211930T1 AT E211930 T1 ATE211930 T1 AT E211930T1 AT 94931415 T AT94931415 T AT 94931415T AT 94931415 T AT94931415 T AT 94931415T AT E211930 T1 ATE211930 T1 AT E211930T1
Authority
AT
Austria
Prior art keywords
biomaterial
glutaraldehyde
calcification
bioprosthetical
tissue
Prior art date
Application number
AT94931415T
Other languages
English (en)
Inventor
Robert J Levy
Danielle Hirsch
Original Assignee
Univ Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22492520&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE211930(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Michigan filed Critical Univ Michigan
Application granted granted Critical
Publication of ATE211930T1 publication Critical patent/ATE211930T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3625—Vascular tissue, e.g. heart valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/21—Acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/216—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with other specific functional groups, e.g. aldehydes, ketones, phenols, quaternary phosphonium groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/02—Treatment of implants to prevent calcification or mineralisation in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/92—Method or apparatus for preparing or treating prosthetic
    • Y10S623/922—Heart

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials For Medical Uses (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Treatment And Processing Of Natural Fur Or Leather (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Saccharide Compounds (AREA)
  • Prostheses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT94931415T 1993-10-21 1994-10-20 Verfahren zur herstellung von verkalkungsbeständigem bioprosthetischem gewebe ATE211930T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/140,722 US5746775A (en) 1988-04-01 1993-10-21 Method of making calcification-resistant bioprosthetic tissue
PCT/US1994/011937 WO1995011047A1 (en) 1993-10-21 1994-10-20 Method of making calcification-resistant bioprosthetic tissue

Publications (1)

Publication Number Publication Date
ATE211930T1 true ATE211930T1 (de) 2002-02-15

Family

ID=22492520

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94931415T ATE211930T1 (de) 1993-10-21 1994-10-20 Verfahren zur herstellung von verkalkungsbeständigem bioprosthetischem gewebe

Country Status (15)

Country Link
US (1) US5746775A (de)
EP (1) EP0729364B1 (de)
JP (1) JP3768528B2 (de)
CN (1) CN1136780A (de)
AT (1) ATE211930T1 (de)
AU (1) AU701897B2 (de)
BR (1) BR9407880B1 (de)
CA (1) CA2174665C (de)
DE (1) DE69429667T2 (de)
ES (1) ES2171470T3 (de)
IL (1) IL111351A (de)
NO (1) NO961541L (de)
NZ (1) NZ275032A (de)
WO (1) WO1995011047A1 (de)
ZA (1) ZA948299B (de)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69523074T2 (de) 1994-07-29 2002-06-06 Edwards Lifesciences Corp., Irvine Verfahren zur behandlung von implantierbaren biologischen geweben zur verringerung von verkalkung
US5931969A (en) * 1994-07-29 1999-08-03 Baxter International Inc. Methods and apparatuses for treating biological tissue to mitigate calcification
USRE40570E1 (en) 1994-07-29 2008-11-11 Edwards Lifesciences Corporation Apparatuses and methods for treating biological tissue to mitigate calcification
US6372228B1 (en) * 1994-11-15 2002-04-16 Kenton W. Gregory Method of producing elastin, elastin-based biomaterials and tropoelastin materials
US6302909B1 (en) 1996-07-31 2001-10-16 St. Jude Medical, Inc. Calcification-resistant biomaterials
US6193749B1 (en) 1996-02-05 2001-02-27 St. Jude Medical, Inc. Calcification-resistant biomaterials
JP2000505667A (ja) * 1996-02-05 2000-05-16 セント ジュード メディカル，インコーポレイテッド 石灰化抵抗性生体材料
US5862806A (en) * 1997-10-30 1999-01-26 Mitroflow International, Inc. Borohydride reduction of biological tissues
US6254635B1 (en) 1998-02-02 2001-07-03 St. Jude Medical, Inc. Calcification-resistant medical articles
US6630001B2 (en) * 1998-06-24 2003-10-07 International Heart Institute Of Montana Foundation Compliant dehyrated tissue for implantation and process of making the same
US6254564B1 (en) 1998-09-10 2001-07-03 Percardia, Inc. Left ventricular conduit with blood vessel graft
US6214054B1 (en) 1998-09-21 2001-04-10 Edwards Lifesciences Corporation Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby
WO2001028604A1 (en) * 1999-10-15 2001-04-26 The Brigham And Women's Hospital, Inc. Fresh, cryopreserved, or minimally fixed cardiac valvular xenografts
US6479079B1 (en) 1999-12-13 2002-11-12 Sulzer Carbomedics Inc. Anticalcification treatments for fixed biomaterials
US6471723B1 (en) 2000-01-10 2002-10-29 St. Jude Medical, Inc. Biocompatible prosthetic tissue
DE10010074B4 (de) 2000-02-28 2005-04-14 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Vorrichtung zur Befestigung und Verankerung von Herzklappenprothesen
DE10010073B4 (de) * 2000-02-28 2005-12-22 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verankerung für implantierbare Herzklappenprothesen
AUPR217300A0 (en) * 2000-12-20 2001-01-25 Ketharanathan, Vettivetpillai Method of creating biological and biosynthetic material for implantation
FR2828263B1 (fr) 2001-08-03 2007-05-11 Philipp Bonhoeffer Dispositif d'implantation d'un implant et procede d'implantation du dispositif
US6878168B2 (en) 2002-01-03 2005-04-12 Edwards Lifesciences Corporation Treatment of bioprosthetic tissues to mitigate post implantation calcification
US8308797B2 (en) * 2002-01-04 2012-11-13 Colibri Heart Valve, LLC Percutaneously implantable replacement heart valve device and method of making same
US20050148949A1 (en) * 2003-07-31 2005-07-07 Gabrielle Thumann Novel instrument for the transplantation of delicate micro-transplants
US7955788B2 (en) 2003-10-30 2011-06-07 Medtronic, Inc. Bioprosthetic tissue preparation with synthetic hydrogels
US20060110370A1 (en) * 2004-11-23 2006-05-25 Pathak Chandrashenkhar P Treatments for reduction of cytotoxicity and viral contamination of implantable medical devices
ES2569494T3 (es) * 2004-12-24 2016-05-11 Admedus Regen Pty Ltd. Un biomaterial implantable y un método de producción del mismo
US7989157B2 (en) * 2005-01-11 2011-08-02 Medtronic, Inc. Solution for storing bioprosthetic tissue used in a biological prosthesis
DE102005003632A1 (de) 2005-01-20 2006-08-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Katheter für die transvaskuläre Implantation von Herzklappenprothesen
US7579381B2 (en) 2005-03-25 2009-08-25 Edwards Lifesciences Corporation Treatment of bioprosthetic tissues to mitigate post implantation calcification
DE102005051849B4 (de) 2005-10-28 2010-01-21 JenaValve Technology Inc., Wilmington Vorrichtung zur Implantation und Befestigung von Herzklappenprothesen
DE102005052628B4 (de) 2005-11-04 2014-06-05 Jenavalve Technology Inc. Selbstexpandierendes, flexibles Drahtgeflecht mit integrierter Klappenprothese für den transvaskulären Herzklappenersatz und ein System mit einer solchen Vorrichtung und einem Einführkatheter
US20070213813A1 (en) 2005-12-22 2007-09-13 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
CN103933612B (zh) * 2006-10-27 2016-06-22 爱德华兹生命科学公司 用于外科植入的生物组织
US7896915B2 (en) 2007-04-13 2011-03-01 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
US9138315B2 (en) 2007-04-13 2015-09-22 Jenavalve Technology Gmbh Medical device for treating a heart valve insufficiency or stenosis
JP5220101B2 (ja) 2007-05-15 2013-06-26 イエナバルブ テクノロジー インク 自己拡張型の心臓弁ステントを挿入するためにカテーテル先端、カテーテルシステムおよび医療挿入システムを操作するためのハンドル
US9101691B2 (en) * 2007-06-11 2015-08-11 Edwards Lifesciences Corporation Methods for pre-stressing and capping bioprosthetic tissue
US8357387B2 (en) 2007-12-21 2013-01-22 Edwards Lifesciences Corporation Capping bioprosthetic tissue to reduce calcification
US8398704B2 (en) 2008-02-26 2013-03-19 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
US8317858B2 (en) * 2008-02-26 2012-11-27 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
WO2011104269A1 (en) 2008-02-26 2011-09-01 Jenavalve Technology Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US9168130B2 (en) 2008-02-26 2015-10-27 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US8465540B2 (en) 2008-02-26 2013-06-18 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis
US20100261662A1 (en) * 2009-04-09 2010-10-14 Endologix, Inc. Utilization of mural thrombus for local drug delivery into vascular tissue
US8468667B2 (en) 2009-05-15 2013-06-25 Jenavalve Technology, Inc. Device for compressing a stent
CN101721745B (zh) * 2009-11-09 2015-04-01 山东省千佛山医院 用于人工心脏瓣膜及其他生物修补材料的驴心包加工方法
EP2542184B1 (de) 2010-03-01 2016-05-25 Colibri Heart Valve LLC Perkutan verabreichbare herzklappe und damit verbundene verfahren
EP3636293A1 (de) 2010-03-23 2020-04-15 Edwards Lifesciences Corporation Verfahren zur bearbeitung eines scheibenförmigen bioprothese-gewebes
US11278406B2 (en) 2010-05-20 2022-03-22 Jenavalve Technology, Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect
US10856978B2 (en) 2010-05-20 2020-12-08 Jenavalve Technology, Inc. Catheter system
CA2799459A1 (en) 2010-05-25 2011-12-01 Jenavalve Technology Inc. Prosthetic heart valve and transcatheter delivered endoprosthesis comprising a prosthetic heart valve and a stent
US8906601B2 (en) 2010-06-17 2014-12-09 Edwardss Lifesciences Corporation Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates
CA2794135C (en) 2010-06-17 2018-01-02 Edwards Lifesciences Corporation Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates
WO2012006124A2 (en) 2010-06-28 2012-01-12 Vela Biosystems Llc Method and apparatus for the endoluminal delivery of intravascular devices
US9351829B2 (en) 2010-11-17 2016-05-31 Edwards Lifesciences Corporation Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability
JP2014507179A (ja) 2010-12-14 2014-03-27 コリブリ ハート バルブ エルエルシー 統合された弁尖を伴う折り畳まれた膜の心臓弁膜尖を含む経皮的にデリバリー可能な心臓弁
WO2012141454A2 (en) * 2011-04-12 2012-10-18 Hans Biomed. Cor. Graft materials derived from mammalian cartilage
US9358107B2 (en) 2011-06-30 2016-06-07 Edwards Lifesciences Corporation Systems, dies, and methods for processing pericardial tissue
WO2013056898A1 (en) 2011-10-21 2013-04-25 Jenavalve Technology Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect
US20140341871A1 (en) * 2011-12-30 2014-11-20 Paul R. Morris Regenerative tissue matrix
EP2849678B1 (de) 2012-05-16 2022-08-10 JenaValve Technology, Inc. Katheterverabreichungssystem zur einführung einer dehnbaren herzklappenprothese sowie medizinische vorrichtung zur behandlung eines herzklappendefekts
US10238771B2 (en) 2012-11-08 2019-03-26 Edwards Lifesciences Corporation Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system
CN105491978A (zh) 2013-08-30 2016-04-13 耶拿阀门科技股份有限公司 用于假体瓣膜的径向可折叠框架及其制造方法
US9615922B2 (en) 2013-09-30 2017-04-11 Edwards Lifesciences Corporation Method and apparatus for preparing a contoured biological tissue
US10959839B2 (en) 2013-10-08 2021-03-30 Edwards Lifesciences Corporation Method for directing cellular migration patterns on a biological tissue
US9555162B2 (en) * 2014-02-24 2017-01-31 Medtronic, Inc. Phospholipid reduction in biological tissue
EP3270825B1 (de) 2015-03-20 2020-04-22 JenaValve Technology, Inc. Herzklappenprothesenzuführsystem
EP3632378B1 (de) 2015-05-01 2024-05-29 JenaValve Technology, Inc. Vorrichtung mit reduzierter herzschrittmacherrate bei herzklappenersatz
CN108535205B (zh) * 2015-07-22 2021-06-22 杭州启明医疗器械股份有限公司 体外生物瓣抗钙化处理方法、钙化评价方法
US10195024B2 (en) * 2015-10-07 2019-02-05 Boston Scientific Scimed, Inc. Porcine small intestine submucosa leaflet material
US11065138B2 (en) 2016-05-13 2021-07-20 Jenavalve Technology, Inc. Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system
CN110392557A (zh) 2017-01-27 2019-10-29 耶拿阀门科技股份有限公司 心脏瓣膜模拟
CA3062547A1 (en) 2017-05-31 2018-12-06 Edwards Lifesciences Corporation Collagen fibers and articles formed therefrom
US10722613B2 (en) 2017-06-29 2020-07-28 St. Jude Medical, Cardiology Division, Inc. Method of preparing calcification-resistant bioprosthetic tissue
US11395726B2 (en) 2017-09-11 2022-07-26 Incubar Llc Conduit vascular implant sealing device for reducing endoleaks
WO2019147585A1 (en) 2018-01-23 2019-08-01 Edwards Lifesciences Corporation Method for pre-stretching implantable biocompatible materials, and materials and devices produced thereby
WO2020092205A1 (en) 2018-11-01 2020-05-07 Edwards Lifesciences Corporation Transcatheter pulmonic regenerative valve
EP3693030A1 (de) * 2019-02-07 2020-08-12 P+F Products + Features GmbH Verfahren zur herstellung von biologischem gewebe für die chirurgische implantation
AU2020399770B2 (en) 2019-12-09 2026-03-12 Edwards Lifesciences Corporation Bioprosthetic tissue preparation
CN111588909A (zh) * 2020-02-24 2020-08-28 科凯(南通)生命科学有限公司 一种生物医用材料防钙化的方法
CN111494716B (zh) * 2020-04-15 2021-12-21 青岛市妇女儿童医院（青岛市妇幼保健院、青岛市残疾儿童医疗康复中心、青岛市新生儿疾病筛查中心） 心脏外科自体心包补片处理器及快速防钙化处理方法
CN113080187B (zh) * 2021-03-31 2022-06-21 上海纽脉医疗科技有限公司 用于去除磷脂和细胞碎片的组合物及去除生物组织上磷脂和细胞碎片的方法
CN113499478B (zh) * 2021-07-07 2022-07-12 成都纽脉生物科技有限公司 一种生物组织材料的处理方法
CN113499479B (zh) * 2021-07-19 2023-03-17 科凯(南通)生命科学有限公司 改性生物材料的制备方法及得到的改性生物材料
BR102021017465A2 (pt) * 2021-09-02 2023-03-14 Labcor Laboratórios Ltda. Método para produção de tecido conjuntivo colágeno preservado, tecido conjuntivo colágeno, seus usos e kit para implante em tecido
CN114504682A (zh) * 2021-11-16 2022-05-17 李平 脐动脉在制备冠脉搭桥的移植血管材料中的应用及制备冠脉搭桥的移植血管材料的方法
US12171658B2 (en) 2022-11-09 2024-12-24 Jenavalve Technology, Inc. Catheter system for sequential deployment of an expandable implant

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US725648A (en) * 1901-03-27 1903-04-21 Otto P Amend Process of tanning hides, skins, or other animal tissues.
US713046A (en) * 1902-04-18 1902-11-11 Otto P Amend Process of tanning hides or other animal tissues.
US2750251A (en) * 1954-07-09 1956-06-12 Ethicon Inc Process for preparing sutures and ligatures
US2970031A (en) * 1955-08-31 1961-01-31 American Cyanamid Co Process for tanning leather
DK114924B (da) * 1963-05-29 1969-08-18 Ethicon Inc Fremgangsmåde til forbedring af trækstyrken og absorptionsevnen af suturmaterialer af collagenfibre.
US3974526A (en) * 1973-07-06 1976-08-17 Dardik Irving I Vascular prostheses and process for producing the same
US3922356A (en) * 1974-04-18 1975-11-25 Tee Pak Inc Sulfite catalyzed aluminum tannage of collagen casing
US4097234A (en) * 1976-12-10 1978-06-27 Nippi, Incorporated Method for preparing dispersion of collagen fiber
US4378224A (en) * 1980-09-19 1983-03-29 Nimni Marcel E Coating for bioprosthetic device and method of making same
IN157379B (de) * 1981-04-30 1986-03-15 Extracorporeal Med Spec
US4323358A (en) * 1981-04-30 1982-04-06 Vascor, Inc. Method for inhibiting mineralization of natural tissue during implantation
FR2523810B1 (fr) * 1982-03-23 1988-11-25 Carpentier Alain Tissu biologique greffable et procede pour sa preparation
US4481009A (en) * 1982-05-13 1984-11-06 American Hospital Supply Corporation Polymer incorporation into implantable biological tissue to inhibit calcification
US4402697A (en) * 1982-08-25 1983-09-06 Extracorporeal Medical Specialties, Inc. Method for inhibiting mineralization of natural tissue during implantation
US4405327A (en) * 1982-08-25 1983-09-20 Extracorporeal Medical Specialties, Inc. Method for inhibiting mineralization of natural tissue during implantation
US4885005A (en) * 1982-11-12 1989-12-05 Baxter International Inc. Surfactant treatment of implantable biological tissue to inhibit calcification
EP0126743B1 (de) * 1982-11-12 1989-04-12 BAXTER INTERNATIONAL INC. (a Delaware corporation) Behandlung einpflanzbarer biologischer gewebe mit oberflächenaktiven mitteln zur verhinderung von kalzifizierung
US5215541A (en) * 1982-11-12 1993-06-01 Baxter International Inc. Surfactant treatment of implantable biological tissue to inhibit calcification
WO1984001894A1 (en) * 1982-11-12 1984-05-24 American Hospital Supply Corp Chemical sterilization of implantable biological tissue
US4597960A (en) * 1983-04-19 1986-07-01 Cohen Edgar C Microencapsulated astringent hemostatic agents and methods of use
US4753652A (en) * 1984-05-04 1988-06-28 Children's Medical Center Corporation Biomaterial implants which resist calcification
US4553974A (en) * 1984-08-14 1985-11-19 Mayo Foundation Treatment of collagenous tissue with glutaraldehyde and aminodiphosphonate calcification inhibitor
US4729139A (en) * 1985-11-05 1988-03-08 Baxter Travenol Selective incorporation of a polymer into implantable biological tissue to inhibit calcification
US4770665A (en) * 1985-11-05 1988-09-13 American Hospital Supply Corporation Elastomeric polymer incorporation into implantable biological tissue to inhibit calcification
US4786287A (en) * 1986-10-10 1988-11-22 Baxter Travenol Laboratories Process for decreasing residual aldehyde levels in implantable bioprosthetic tissue
US4798611A (en) * 1986-10-14 1989-01-17 Hancock Jaffe Laboratories Enhancement of xenogeneic tissue
US4838888A (en) * 1987-04-17 1989-06-13 Baxter Travenol Laboratories, Inc. Calcification mitigation of implantable bioprostheses
JP2529112B2 (ja) * 1987-08-31 1996-08-28 株式会社 高研 生体弁
US4976733A (en) * 1988-02-03 1990-12-11 Biomedical Design, Inc. Prevention of prosthesis calcification
US5094661A (en) * 1988-04-01 1992-03-10 The University Of Michigan Calcification-resistant materials and methods of making same through use of trivalent aluminum
JPH04503356A (ja) * 1989-02-17 1992-06-18 バクスター　インターナショナル　インコーポレーテッド 生充填移植片の石灰化軽減
US5002566A (en) * 1989-02-17 1991-03-26 Baxter International Inc. Calcification mitigation of bioprosthetic implants
US5476516A (en) * 1992-03-13 1995-12-19 Albert Einstein College Of Medicine Of Yeshiva University Anticalcification treatment for aldehyde-tanned biological tissue
US5447536A (en) * 1994-02-17 1995-09-05 Biomedical Design, Inc. Method for fixation of biological tissue

Also Published As

Publication number Publication date
NO961541D0 (no) 1996-04-18
AU8099094A (en) 1995-05-08
CN1136780A (zh) 1996-11-27
EP0729364A1 (de) 1996-09-04
ES2171470T3 (es) 2002-09-16
ZA948299B (en) 1996-07-22
CA2174665C (en) 2007-06-05
US5746775A (en) 1998-05-05
EP0729364B1 (de) 2002-01-16
DE69429667T2 (de) 2002-08-29
DE69429667D1 (de) 2002-02-21
NO961541L (no) 1996-06-05
AU701897B2 (en) 1999-02-11
BR9407880B1 (pt) 2009-01-13
IL111351A0 (en) 1994-12-29
BR9407880A (pt) 1996-10-29
JP3768528B2 (ja) 2006-04-19
NZ275032A (en) 1998-10-28
WO1995011047A1 (en) 1995-04-27
EP0729364A4 (de) 1996-09-25
IL111351A (en) 1999-04-11
JPH09505216A (ja) 1997-05-27
CA2174665A1 (en) 1995-04-27

Similar Documents

Publication Publication Date Title
DE69429667D1 (de) Verfahren zur herstellung von verkalkungsbeständigem bioprosthetischem gewebe
US5645587A (en) Prevention of calcification and degeneration of biological tissue grafts for implantation in humans
US4553974A (en) Treatment of collagenous tissue with glutaraldehyde and aminodiphosphonate calcification inhibitor
US5674298A (en) Calcification-resistant bioprosthetic tissue and methods of making same
US5476516A (en) Anticalcification treatment for aldehyde-tanned biological tissue
CA2312376C (en) Method for inhibiting calcification of aldehyde-fixed bioprosthetic materials
US6093530A (en) Non-calcific biomaterial by glutaraldehyde followed by oxidative fixation
CA1221641A (en) Implantable biological tissue and process for preparation thereof
CA2185447C (en) Treated tissue for implantation and preparation methods
DE69719992T2 (de) Verfahren zur verhinderung von verkalkung von glutaraldehyd fixierten implantaten und artikeln die nach dem verfahren hergestellt sind
DE69523074T2 (de) Verfahren zur behandlung von implantierbaren biologischen geweben zur verringerung von verkalkung
Bodnar et al. Damage of porcine aortic valve tissue caused by the surfactant sodiumdodecylsulphate
ATE316795T1 (de) Mesenchymale stammzellen für die prävention und behandlung von immunantworten bei transplantationen
Schoen et al. Heart valve bioprostheses: antimineralization
JPS6156101A (ja) 表面活性ベタインによる移植可能な組織の鉱化を遅延させる方法

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties