ATE212021T1 - Piperidinderivate als ltd4 und h1 antagonisten - Google Patents
Piperidinderivate als ltd4 und h1 antagonistenInfo
- Publication number
- ATE212021T1 ATE212021T1 AT98118065T AT98118065T ATE212021T1 AT E212021 T1 ATE212021 T1 AT E212021T1 AT 98118065 T AT98118065 T AT 98118065T AT 98118065 T AT98118065 T AT 98118065T AT E212021 T1 ATE212021 T1 AT E212021T1
- Authority
- AT
- Austria
- Prior art keywords
- ltd4
- antagonists
- chem
- single bond
- piperidine derivatives
- Prior art date
Links
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical class C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- YEESKJGWJFYOOK-IJHYULJSSA-N leukotriene D4 Chemical compound CCCCC\C=C/C\C=C/C=C/C=C/[C@H]([C@@H](O)CCCC(O)=O)SC[C@H](N)C(=O)NCC(O)=O YEESKJGWJFYOOK-IJHYULJSSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 206010041349 Somnolence Diseases 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 230000002590 anti-leukotriene effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 150000003053 piperidines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003258 trimethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])[*:1] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25984897 | 1997-09-25 | ||
| JP26159997 | 1997-09-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE212021T1 true ATE212021T1 (de) | 2002-02-15 |
Family
ID=26544316
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98118065T ATE212021T1 (de) | 1997-09-25 | 1998-09-23 | Piperidinderivate als ltd4 und h1 antagonisten |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6107308A (de) |
| EP (1) | EP0905134B1 (de) |
| KR (1) | KR100535324B1 (de) |
| AT (1) | ATE212021T1 (de) |
| DE (1) | DE69803151T2 (de) |
| ES (1) | ES2172071T3 (de) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3193508B2 (ja) * | 1993-03-05 | 2001-07-30 | 興和株式会社 | ピペリジン誘導体 |
| US5756518A (en) * | 1996-04-02 | 1998-05-26 | Kowa Co., Ltd. | Phenylene derivatives |
| DE19629670A1 (de) * | 1996-07-23 | 1998-01-29 | Friedolf Mutschler | Verfahren und Vorrichtung zur Lenkung des Sonnenlichtes und Temperaturregelung |
-
1998
- 1998-09-18 KR KR1019980038720A patent/KR100535324B1/ko not_active Expired - Fee Related
- 1998-09-23 US US09/158,775 patent/US6107308A/en not_active Expired - Fee Related
- 1998-09-23 EP EP98118065A patent/EP0905134B1/de not_active Expired - Lifetime
- 1998-09-23 ES ES98118065T patent/ES2172071T3/es not_active Expired - Lifetime
- 1998-09-23 DE DE69803151T patent/DE69803151T2/de not_active Expired - Lifetime
- 1998-09-23 AT AT98118065T patent/ATE212021T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR100535324B1 (ko) | 2006-04-21 |
| EP0905134A1 (de) | 1999-03-31 |
| ES2172071T3 (es) | 2002-09-16 |
| KR19990029946A (ko) | 1999-04-26 |
| DE69803151T2 (de) | 2002-08-14 |
| US6107308A (en) | 2000-08-22 |
| EP0905134B1 (de) | 2002-01-16 |
| DE69803151D1 (de) | 2002-02-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |