ATE212350T1 - Chemisch, biochemisch und biologisch verarbeitung bei dünner schichten - Google Patents
Chemisch, biochemisch und biologisch verarbeitung bei dünner schichtenInfo
- Publication number
- ATE212350T1 ATE212350T1 AT96918007T AT96918007T ATE212350T1 AT E212350 T1 ATE212350 T1 AT E212350T1 AT 96918007 T AT96918007 T AT 96918007T AT 96918007 T AT96918007 T AT 96918007T AT E212350 T1 ATE212350 T1 AT E212350T1
- Authority
- AT
- Austria
- Prior art keywords
- thin film
- biochemical
- sequencing
- film coating
- chemical
- Prior art date
Links
- 239000000126 substance Substances 0.000 title abstract 3
- 238000009501 film coating Methods 0.000 abstract 4
- 239000010409 thin film Substances 0.000 abstract 4
- 239000002245 particle Substances 0.000 abstract 3
- 238000012163 sequencing technique Methods 0.000 abstract 3
- 230000003851 biochemical process Effects 0.000 abstract 2
- 230000031018 biological processes and functions Effects 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- 230000003287 optical effect Effects 0.000 abstract 2
- 238000003786 synthesis reaction Methods 0.000 abstract 2
- 238000001712 DNA sequencing Methods 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 238000002515 oligonucleotide synthesis Methods 0.000 abstract 1
- 238000010647 peptide synthesis reaction Methods 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00457—Dispensing or evacuation of the solid phase support
- B01J2219/00459—Beads
- B01J2219/00468—Beads by manipulation of individual beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/005—Beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/0059—Sequential processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00646—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports
- B01J2219/00648—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports by the use of solid beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00709—Type of synthesis
- B01J2219/00711—Light-directed synthesis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Nanotechnology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Materials Engineering (AREA)
- Composite Materials (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Microbiology (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/462,485 US5776674A (en) | 1995-06-05 | 1995-06-05 | Chemical biochemical and biological processing in thin films |
| PCT/US1996/008633 WO1996039417A1 (en) | 1995-06-05 | 1996-06-04 | Chemical, biochemical and biological processing in thin films |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE212350T1 true ATE212350T1 (de) | 2002-02-15 |
Family
ID=23836579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96918007T ATE212350T1 (de) | 1995-06-05 | 1996-06-04 | Chemisch, biochemisch und biologisch verarbeitung bei dünner schichten |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5776674A (de) |
| EP (1) | EP0846124B1 (de) |
| JP (1) | JPH11507514A (de) |
| KR (1) | KR19990022308A (de) |
| CN (1) | CN1192745A (de) |
| AT (1) | ATE212350T1 (de) |
| AU (1) | AU698306B2 (de) |
| CA (1) | CA2223496A1 (de) |
| DE (1) | DE69618790T2 (de) |
| WO (1) | WO1996039417A1 (de) |
Families Citing this family (85)
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|---|---|---|---|---|
| WO1998035012A2 (en) | 1997-02-12 | 1998-08-13 | Chan Eugene Y | Methods and products for analyzing polymers |
| US6055106A (en) * | 1998-02-03 | 2000-04-25 | Arch Development Corporation | Apparatus for applying optical gradient forces |
| US7794946B1 (en) | 1998-02-04 | 2010-09-14 | Life Technologies Corporation | Microarray and uses therefor |
| US6139831A (en) * | 1998-05-28 | 2000-10-31 | The Rockfeller University | Apparatus and method for immobilizing molecules onto a substrate |
| US20020119579A1 (en) * | 1998-07-14 | 2002-08-29 | Peter Wagner | Arrays devices and methods of use thereof |
| US6576478B1 (en) | 1998-07-14 | 2003-06-10 | Zyomyx, Inc. | Microdevices for high-throughput screening of biomolecules |
| US6897073B2 (en) * | 1998-07-14 | 2005-05-24 | Zyomyx, Inc. | Non-specific binding resistant protein arrays and methods for making the same |
| US6406921B1 (en) | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
| US6682942B1 (en) | 1998-07-14 | 2004-01-27 | Zyomyx, Inc. | Microdevices for screening biomolecules |
| US7079241B2 (en) | 2000-04-06 | 2006-07-18 | Invitrogen Corp. | Spatial positioning of spectrally labeled beads |
| US6607888B2 (en) | 1998-10-20 | 2003-08-19 | Wisconsin Alumni Research Foundation | Method for analyzing nucleic acid reactions |
| US6221592B1 (en) | 1998-10-20 | 2001-04-24 | Wisconsin Alumi Research Foundation | Computer-based methods and systems for sequencing of individual nucleic acid molecules |
| US6528801B1 (en) * | 1998-11-04 | 2003-03-04 | The Research Foundation Of State University Of New York | Method and apparatus for detecting radiation |
| US6130745A (en) * | 1999-01-07 | 2000-10-10 | Biometric Imaging, Inc. | Optical autofocus for use with microtiter plates |
| JP3468149B2 (ja) * | 1999-02-19 | 2003-11-17 | 松下電器産業株式会社 | 微細物体の操作装置および操作方法 |
| AU4856100A (en) * | 1999-05-17 | 2000-12-05 | Stephen T Flock | Electromagnetic energy driven separation methods |
| AU5723700A (en) | 1999-05-25 | 2000-12-12 | Praelux Incorporated | Method for sequency and characterizing polymeric biomolecules using aptamers anda method for producing aptamers |
| US6420112B2 (en) | 1999-07-21 | 2002-07-16 | The Regents Of The University Of California | DNA attachment to support structures |
| AU7105300A (en) | 1999-09-03 | 2001-04-10 | Lifebeam Technologies, Inc. | Optical system for rapid polymer analysis |
| AU2277001A (en) * | 1999-12-20 | 2001-07-03 | Penn State Research Foundation, The | Deposited thin films and their use in detection, attachment, and bio-medical applications |
| US20030186426A1 (en) * | 2000-03-15 | 2003-10-02 | The Regents Of The University Of California | Multichannel flow cell for interacting single optically trapped, DNA molecules with different chemical species |
| AU2001259512B2 (en) * | 2000-05-04 | 2007-03-01 | Yale University | High density protein arrays for screening of protein activity |
| CA2391317A1 (en) * | 2000-07-26 | 2002-01-31 | The Regent Of The University Of California | Manipulation of live cells and inorganic objects with optical micro beam arrays |
| US6744038B2 (en) | 2000-11-13 | 2004-06-01 | Genoptix, Inc. | Methods of separating particles using an optical gradient |
| US6784420B2 (en) * | 2000-11-13 | 2004-08-31 | Genoptix, Inc. | Method of separating particles using an optical gradient |
| US20030007894A1 (en) | 2001-04-27 | 2003-01-09 | Genoptix | Methods and apparatus for use of optical forces for identification, characterization and/or sorting of particles |
| US6936811B2 (en) * | 2000-11-13 | 2005-08-30 | Genoptix, Inc. | Method for separating micro-particles |
| US20020160470A1 (en) * | 2000-11-13 | 2002-10-31 | Genoptix | Methods and apparatus for generating and utilizing linear moving optical gradients |
| US6833542B2 (en) * | 2000-11-13 | 2004-12-21 | Genoptix, Inc. | Method for sorting particles |
| US20020123112A1 (en) * | 2000-11-13 | 2002-09-05 | Genoptix | Methods for increasing detection sensitivity in optical dielectric sorting systems |
| US6836592B2 (en) * | 2000-11-20 | 2004-12-28 | Aculight Corporation | Method and apparatus for fiber Bragg grating production |
| US6778724B2 (en) | 2000-11-28 | 2004-08-17 | The Regents Of The University Of California | Optical switching and sorting of biological samples and microparticles transported in a micro-fluidic device, including integrated bio-chip devices |
| AU2002227156A1 (en) | 2000-12-01 | 2002-06-11 | Visigen Biotechnologies, Inc. | Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity |
| DE10100247A1 (de) * | 2001-01-05 | 2002-07-11 | Leica Microsystems | Interferenzmikroskop und Verfahren zum Betrieb eines Interferenzmikroskops |
| US6416190B1 (en) | 2001-04-27 | 2002-07-09 | University Of Chicago | Apparatus for using optical tweezers to manipulate materials |
| US20040009540A1 (en) * | 2001-04-27 | 2004-01-15 | Genoptix, Inc | Detection and evaluation of cancer cells using optophoretic analysis |
| US20030194755A1 (en) * | 2001-04-27 | 2003-10-16 | Genoptix, Inc. | Early detection of apoptotic events and apoptosis using optophoretic analysis |
| WO2003001178A2 (en) * | 2001-06-20 | 2003-01-03 | Arryx, Inc. | Configurable dynamic three dimensional array |
| CN1854778A (zh) | 2001-06-20 | 2006-11-01 | 阿尔利克斯公司 | 光开关和光路由器以及光滤波器 |
| US20030143612A1 (en) * | 2001-07-18 | 2003-07-31 | Pointilliste, Inc. | Collections of binding proteins and tags and uses thereof for nested sorting and high throughput screening |
| US6710877B2 (en) * | 2001-07-23 | 2004-03-23 | Corning Incorporated | Apparatus and methods for determining biomolecular interactions |
| US6767731B2 (en) * | 2001-08-27 | 2004-07-27 | Intel Corporation | Electron induced fluorescent method for nucleic acid sequencing |
| GB0121700D0 (en) * | 2001-09-07 | 2001-10-31 | Univ Leicester | Detection of fluorescence |
| US6972173B2 (en) * | 2002-03-14 | 2005-12-06 | Intel Corporation | Methods to increase nucleotide signals by raman scattering |
| US6852492B2 (en) * | 2001-09-24 | 2005-02-08 | Intel Corporation | Nucleic acid sequencing by raman monitoring of uptake of precursors during molecular replication |
| US6982165B2 (en) * | 2001-09-24 | 2006-01-03 | Intel Corporation | Nucleic acid sequencing by raman monitoring of molecular deconstruction |
| US7238477B2 (en) * | 2001-09-24 | 2007-07-03 | Intel Corporation | Methods to increase nucleotide signals by Raman scattering |
| US7309568B2 (en) * | 2001-09-26 | 2007-12-18 | Hitachi, Ltd. | Method in inspecting DNA and apparatus therefor |
| US20030119177A1 (en) * | 2001-11-15 | 2003-06-26 | Lewis Gruber | Sample chip |
| US20040110208A1 (en) * | 2002-03-26 | 2004-06-10 | Selena Chan | Methods and device for DNA sequencing using surface enhanced Raman scattering (SERS) |
| US7476501B2 (en) * | 2002-03-26 | 2009-01-13 | Intel Corporation | Methods and device for DNA sequencing using surface enhanced raman scattering (SERS) |
| US20040180363A1 (en) * | 2002-04-12 | 2004-09-16 | Dymeka Gossett Rooks Pitts Pllc | Configurable dynamic three dimensional array |
| US20030211461A1 (en) * | 2002-05-01 | 2003-11-13 | Genoptix, Inc | Optophoretic detection of durgs exhibiting inhibitory effect on Bcr-Abl positive tumor cells |
| US8278055B2 (en) * | 2002-05-01 | 2012-10-02 | Intel Corporation | Methods and device for analyte characterization |
| US7744816B2 (en) * | 2002-05-01 | 2010-06-29 | Intel Corporation | Methods and device for biomolecule characterization |
| US20040033539A1 (en) * | 2002-05-01 | 2004-02-19 | Genoptix, Inc | Method of using optical interrogation to determine a biological property of a cell or population of cells |
| US7005264B2 (en) * | 2002-05-20 | 2006-02-28 | Intel Corporation | Method and apparatus for nucleic acid sequencing and identification |
| US20040053209A1 (en) * | 2002-09-12 | 2004-03-18 | Genoptix, Inc | Detection and evaluation of topoisomerase inhibitors using optophoretic analysis |
| US7361821B2 (en) * | 2002-09-20 | 2008-04-22 | Intel Corporation | Controlled alignment of nanobarcodes encoding specific information for scanning probe microscopy (SPM) reading |
| WO2004038037A2 (en) * | 2002-09-20 | 2004-05-06 | Intel Corporation | Controlled alignment of nano-barcodes encoding specific information for scanning probe microscopy (spm) reading |
| US20040067167A1 (en) * | 2002-10-08 | 2004-04-08 | Genoptix, Inc. | Methods and apparatus for optophoretic diagnosis of cells and particles |
| US7606403B2 (en) | 2002-10-17 | 2009-10-20 | Intel Corporation | Model-based fusion of scanning probe microscopic images for detection and identification of molecular structures |
| DE10250247B4 (de) * | 2002-10-28 | 2006-06-01 | Leica Microsystems Cms Gmbh | Probenträger für die Mikroskopie und Verfahren zum Anfertigen eines Probenträgers |
| US20040121474A1 (en) * | 2002-12-19 | 2004-06-24 | Genoptix, Inc | Detection and evaluation of chemically-mediated and ligand-mediated t-cell activation using optophoretic analysis |
| US20040121307A1 (en) * | 2002-12-19 | 2004-06-24 | Genoptix, Inc | Early detection of cellular differentiation using optophoresis |
| DE20306138U1 (de) | 2003-04-16 | 2003-09-04 | Monajembashi, Shamci, Dr., 69126 Heidelberg | Präparat, insbesondere für die Handhabung mittels einer optischen Pinzette |
| US20040248323A1 (en) * | 2003-06-09 | 2004-12-09 | Protometrix, Inc. | Methods for conducting assays for enzyme activity on protein microarrays |
| IL157206A0 (en) * | 2003-08-03 | 2004-02-19 | Correlating spatial position of chemical species on a substrate with molecular weight, structure and chemical reactivity | |
| EP1668355A4 (de) * | 2003-08-28 | 2011-11-09 | Celula Inc | Verfahren und vorrichtung zur sortierung von zellen unter verwendung eines optischen schalters in einem mikrofluidischen kanalnetzwerk |
| US7067328B2 (en) * | 2003-09-25 | 2006-06-27 | Nanosys, Inc. | Methods, devices and compositions for depositing and orienting nanostructures |
| DE10359189B4 (de) * | 2003-12-17 | 2005-12-22 | Forschungszentrum Jülich GmbH | Verfahren und Vorrichtung zur Elektrofusionierung von Zellen |
| US20050147976A1 (en) * | 2003-12-29 | 2005-07-07 | Xing Su | Methods for determining nucleotide sequence information |
| US20050147979A1 (en) * | 2003-12-30 | 2005-07-07 | Intel Corporation | Nucleic acid sequencing by Raman monitoring of uptake of nucleotides during molecular replication |
| US20050147980A1 (en) * | 2003-12-30 | 2005-07-07 | Intel Corporation | Nucleic acid sequencing by Raman monitoring of uptake of nucleotides during molecular replication |
| US7442339B2 (en) * | 2004-03-31 | 2008-10-28 | Intel Corporation | Microfluidic apparatus, Raman spectroscopy systems, and methods for performing molecular reactions |
| JP2005337730A (ja) * | 2004-05-24 | 2005-12-08 | Nara Institute Of Science & Technology | 測定システム |
| US7736818B2 (en) | 2004-12-27 | 2010-06-15 | Inphase Technologies, Inc. | Holographic recording medium and method of making it |
| WO2007038260A2 (en) * | 2005-09-23 | 2007-04-05 | Massachusetts Institute Of Technology | Systems and methods for force-fluorescence microscopy |
| WO2007038259A2 (en) | 2005-09-23 | 2007-04-05 | Massachusetts Institute Of Technology | Optical trapping with a semiconductor |
| US9664619B2 (en) | 2008-04-28 | 2017-05-30 | President And Fellows Of Harvard College | Microfluidic device for storage and well-defined arrangement of droplets |
| US20100273681A1 (en) * | 2009-04-27 | 2010-10-28 | Wisconsin Alumni Research Foundation | Combinatorial chemistry reaction cell with optical tweezers |
| EP2895909B1 (de) * | 2012-09-13 | 2022-07-06 | Brandeis University | Kühlsysteme und -verfahren für hochauflösende cryofluoreszenzlicht-mikroskopie und andere anwendungen |
| US12013521B2 (en) | 2020-06-29 | 2024-06-18 | Mgi Tech Co., Ltd. | Systems and methods for optical scanning and imaging through a fluid medium for nucleic acid sequencing |
| CN113663624A (zh) * | 2021-08-04 | 2021-11-19 | 北京科技大学 | 一种制备超细阴极射线荧光粉的设备 |
| US12560480B2 (en) * | 2022-11-08 | 2026-02-24 | Mgi Tech Co., Ltd. | Immersion imaging systems and methods for flowcells |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4893886A (en) * | 1987-09-17 | 1990-01-16 | American Telephone And Telegraph Company | Non-destructive optical trap for biological particles and method of doing same |
| US5079169A (en) * | 1990-05-22 | 1992-01-07 | The Regents Of The Stanford Leland Junior University | Method for optically manipulating polymer filaments |
| JP3129471B2 (ja) * | 1991-06-01 | 2001-01-29 | 科学技術振興事業団 | マルチビーム微粒子操作方法 |
| CA2124087C (en) * | 1991-11-22 | 2002-10-01 | James L. Winkler | Combinatorial strategies for polymer synthesis |
| CA2134474C (en) * | 1992-05-01 | 1999-07-06 | The Trustees Of The University Of Pennsylvania | Microfabricated sperm handling devices |
| CA2155186A1 (en) * | 1993-02-01 | 1994-08-18 | Kevin M. Ulmer | Methods and apparatus for dna sequencing |
-
1995
- 1995-06-05 US US08/462,485 patent/US5776674A/en not_active Expired - Fee Related
-
1996
- 1996-06-04 CN CN96196054A patent/CN1192745A/zh active Pending
- 1996-06-04 AT AT96918007T patent/ATE212350T1/de not_active IP Right Cessation
- 1996-06-04 WO PCT/US1996/008633 patent/WO1996039417A1/en not_active Ceased
- 1996-06-04 CA CA002223496A patent/CA2223496A1/en not_active Abandoned
- 1996-06-04 KR KR1019970708788A patent/KR19990022308A/ko not_active Withdrawn
- 1996-06-04 AU AU60370/96A patent/AU698306B2/en not_active Ceased
- 1996-06-04 EP EP96918007A patent/EP0846124B1/de not_active Expired - Lifetime
- 1996-06-04 JP JP9501167A patent/JPH11507514A/ja not_active Withdrawn
- 1996-06-04 DE DE69618790T patent/DE69618790T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU6037096A (en) | 1996-12-24 |
| AU698306B2 (en) | 1998-10-29 |
| CA2223496A1 (en) | 1996-12-12 |
| DE69618790D1 (de) | 2002-03-14 |
| EP0846124B1 (de) | 2002-01-23 |
| JPH11507514A (ja) | 1999-07-06 |
| KR19990022308A (ko) | 1999-03-25 |
| WO1996039417A1 (en) | 1996-12-12 |
| US5776674A (en) | 1998-07-07 |
| DE69618790T2 (de) | 2002-09-05 |
| EP0846124A1 (de) | 1998-06-10 |
| CN1192745A (zh) | 1998-09-09 |
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| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |