ATE212849T1 - Langwirkende, injezierbare, parasitizide zubereitung und verfahren zu ihrer herstellung - Google Patents
Langwirkende, injezierbare, parasitizide zubereitung und verfahren zu ihrer herstellungInfo
- Publication number
- ATE212849T1 ATE212849T1 AT98200868T AT98200868T ATE212849T1 AT E212849 T1 ATE212849 T1 AT E212849T1 AT 98200868 T AT98200868 T AT 98200868T AT 98200868 T AT98200868 T AT 98200868T AT E212849 T1 ATE212849 T1 AT E212849T1
- Authority
- AT
- Austria
- Prior art keywords
- injectable
- final
- acting
- production
- long
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000000590 parasiticidal effect Effects 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 5
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 4
- AZSNMRSAGSSBNP-UHFFFAOYSA-N 22,23-dihydroavermectin B1a Natural products C1CC(C)C(C(C)CC)OC21OC(CC=C(C)C(OC1OC(C)C(OC3OC(C)C(O)C(OC)C3)C(OC)C1)C(C)C=CC=C1C3(C(C(=O)O4)C=C(C)C(O)C3OC1)O)CC4C2 AZSNMRSAGSSBNP-UHFFFAOYSA-N 0.000 abstract 2
- SPBDXSGPUHCETR-JFUDTMANSA-N 8883yp2r6d Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O[C@@H]([C@@H](C)CC4)C(C)C)O3)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C.C1C[C@H](C)[C@@H]([C@@H](C)CC)O[C@@]21O[C@H](C\C=C(C)\[C@@H](O[C@@H]1O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C1)[C@@H](C)\C=C\C=C/1[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\1)O)C[C@H]4C2 SPBDXSGPUHCETR-JFUDTMANSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 235000011187 glycerol Nutrition 0.000 abstract 2
- 229960002418 ivermectin Drugs 0.000 abstract 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AR9701168 | 1997-03-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE212849T1 true ATE212849T1 (de) | 2002-02-15 |
Family
ID=3461002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98200868T ATE212849T1 (de) | 1997-03-21 | 1998-03-17 | Langwirkende, injezierbare, parasitizide zubereitung und verfahren zu ihrer herstellung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6054140A (de) |
| EP (1) | EP0867186B1 (de) |
| AT (1) | ATE212849T1 (de) |
| AU (1) | AU726556B2 (de) |
| DE (1) | DE69803710T2 (de) |
| ES (1) | ES2173545T3 (de) |
| NZ (1) | NZ330005A (de) |
| ZA (1) | ZA981925B (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2753377B1 (fr) * | 1996-09-19 | 1999-09-24 | Rhone Merieux | Nouvelle association parasiticide a base de 1-n-phenylpyra- zoles et de lactones macrocycliques endectocides |
| US6426333B1 (en) | 1996-09-19 | 2002-07-30 | Merial | Spot-on formulations for combating parasites |
| NZ335166A (en) | 1999-04-14 | 2001-11-30 | Ashmont Holdings Ltd | Anthelmintic composition containing triclabendazole in at least one solvent |
| US6998131B2 (en) * | 1996-09-19 | 2006-02-14 | Merial Limited | Spot-on formulations for combating parasites |
| AUPP279698A0 (en) * | 1998-04-03 | 1998-04-30 | Sunscape Developments Limited | Sustained release formulation |
| US6340672B1 (en) * | 2000-02-16 | 2002-01-22 | Phoenix Scientific, Inc. | Parasiticidal formulation and a method of making this formulation |
| DE10063865A1 (de) * | 2000-12-21 | 2002-06-27 | Bayer Ag | Verwendung von Pyrazoloximen als Parasitizide |
| BG64140B1 (bg) * | 2000-12-21 | 2004-02-27 | "Биовет" Ад | Състав за растителна защита с инсектицидно и акарицидно действие |
| US20050009762A1 (en) * | 2003-06-06 | 2005-01-13 | Strobel Michael Albert | Application of water and organic solvent soluble ivermectin for topical and oral use |
| US6627613B2 (en) | 2001-07-23 | 2003-09-30 | Michael A. Strobel | Application of water and organic solvent soluble ivermectin for topical and oral use |
| NZ520295A (en) * | 2002-07-19 | 2005-04-29 | Ashmont Holdings Ltd | Anthelmintic formulations comprising levamisole and either an avermectin or milbemycin |
| AU2006100530B4 (en) * | 2002-07-19 | 2006-08-03 | Merial Ltd | Levamisole, Avermectins or similsr in pyrrolidone solvent |
| US11638714B2 (en) | 2020-11-10 | 2023-05-02 | Mountain Valley Md Inc | Water dissolvable macrocyclic lactone cyclodextrin complexes |
| US11077134B1 (en) | 2020-11-10 | 2021-08-03 | Mountain Valley Md Inc | Water dissolvable macrocyclic lactone cyclodextrin complexes |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4389397A (en) * | 1980-08-04 | 1983-06-21 | Merck & Co., Inc. | Solubilization of ivermectin in water |
| NZ210505A (en) * | 1983-12-22 | 1988-06-30 | Merck & Co Inc | Parasiticidal compositions containing avermectin or milbemycin derivatives |
| EP0298423A3 (de) * | 1987-07-07 | 1989-10-25 | Kumiai Chemical Industry Co., Ltd. | KSB-1939-Antibiotikum-Derivate und Verfahren zu ihrer Herstellung sowie diese enthaltenden pestiziden Zusammensetzungen |
| DE3727648A1 (de) * | 1987-08-19 | 1989-03-02 | Bayer Ag | Neue avermectin derivate, verfahren zu ihrer herstellung und ihre verwendung |
| US5446070A (en) * | 1991-02-27 | 1995-08-29 | Nover Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| IL98599A (en) * | 1990-06-28 | 1995-06-29 | Merck & Co Inc | Stable salts of 4"-deoxy-4"-epi-methylamino avermectin b1a/b1b and insecticidal compositions containing them |
-
1998
- 1998-03-06 US US09/035,870 patent/US6054140A/en not_active Expired - Lifetime
- 1998-03-06 ZA ZA981925A patent/ZA981925B/xx unknown
- 1998-03-17 DE DE69803710T patent/DE69803710T2/de not_active Expired - Lifetime
- 1998-03-17 AT AT98200868T patent/ATE212849T1/de not_active IP Right Cessation
- 1998-03-17 ES ES98200868T patent/ES2173545T3/es not_active Expired - Lifetime
- 1998-03-17 EP EP98200868A patent/EP0867186B1/de not_active Expired - Lifetime
- 1998-03-18 AU AU59367/98A patent/AU726556B2/en not_active Ceased
- 1998-03-20 NZ NZ330005A patent/NZ330005A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU726556B2 (en) | 2000-11-09 |
| DE69803710T2 (de) | 2002-11-21 |
| NZ330005A (en) | 1999-06-29 |
| DE69803710D1 (de) | 2002-03-21 |
| EP0867186B1 (de) | 2002-02-06 |
| US6054140A (en) | 2000-04-25 |
| ZA981925B (en) | 1998-10-23 |
| AU5936798A (en) | 1998-09-24 |
| ES2173545T3 (es) | 2002-10-16 |
| EP0867186A1 (de) | 1998-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |