ATE213228T1 - Oxidatives verfahren zur herstellung von narwedin-derivaten - Google Patents

Oxidatives verfahren zur herstellung von narwedin-derivaten

Info

Publication number
ATE213228T1
ATE213228T1 AT96908286T AT96908286T ATE213228T1 AT E213228 T1 ATE213228 T1 AT E213228T1 AT 96908286 T AT96908286 T AT 96908286T AT 96908286 T AT96908286 T AT 96908286T AT E213228 T1 ATE213228 T1 AT E213228T1
Authority
AT
Austria
Prior art keywords
producing
compound
formula
oxidative process
narwedine
Prior art date
Application number
AT96908286T
Other languages
English (en)
Inventor
James Henshilwood
Nicholas Bernard Johnson
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE213228T1 publication Critical patent/ATE213228T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
AT96908286T 1995-04-03 1996-04-02 Oxidatives verfahren zur herstellung von narwedin-derivaten ATE213228T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9506843.3A GB9506843D0 (en) 1995-04-03 1995-04-03 Oxidative process and products thereof
PCT/GB1996/000815 WO1996031458A1 (en) 1995-04-03 1996-04-02 Oxidative process for preparing narwedine derivatives

Publications (1)

Publication Number Publication Date
ATE213228T1 true ATE213228T1 (de) 2002-02-15

Family

ID=10772408

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96908286T ATE213228T1 (de) 1995-04-03 1996-04-02 Oxidatives verfahren zur herstellung von narwedin-derivaten

Country Status (12)

Country Link
US (2) US6084094A (de)
EP (1) EP0819112B1 (de)
AT (1) ATE213228T1 (de)
AU (1) AU716794B2 (de)
CA (1) CA2215633C (de)
DE (1) DE69619230T2 (de)
DK (1) DK0819112T3 (de)
ES (1) ES2171661T3 (de)
GB (1) GB9506843D0 (de)
PT (1) PT819112E (de)
WO (1) WO1996031458A1 (de)
ZA (1) ZA962677B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9506843D0 (en) * 1995-04-03 1995-05-24 Chiroscience Ltd Oxidative process and products thereof
US7307162B2 (en) * 2003-09-26 2007-12-11 Scinopharm Taiwan, Ltd. Resolution of a narwedine amide derivative
US20050191349A1 (en) * 2003-12-31 2005-09-01 Garth Boehm Galantamine formulations
CA2552114A1 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Solid dosage formulations of galantamine
AR054753A1 (es) * 2005-05-03 2007-07-11 Medichem Sa Sintesis y preparaciones de narwedina galantamina y compuestos relacionados
EP2146719B1 (de) 2007-04-12 2013-08-14 ScinoPharm Taiwan, Ltd. Verfahren zur herstellung von galantamin
KR102392407B1 (ko) 2014-03-07 2022-04-29 디엔에이 제노텍 인코퍼레이티드 생물학적 샘플에서 핵산을 안정화하기 위한 조성물 및 방법
CN104592243B (zh) * 2014-12-19 2016-08-24 北京大学 加兰他敏和力克拉敏的不对称合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL122665B1 (en) * 1978-11-21 1982-08-31 Edinen Zentar Chim Process for preparing novel dienones of narvedine type and their derivatives
US4290862A (en) * 1979-11-14 1981-09-22 Edinen Centar P Chimia Method for the preparation of narwedine-type enones
DE3856594D1 (de) 1987-05-04 2008-11-27 Bonnie Davis Mittel zur behandlung der alzheimer-krankheit
AT401058B (de) 1994-10-21 1996-06-25 Waldheim Pharmazeutika Gmbh Verfahren zum herstellen von derivaten des 4a,5, 9,10,11,12,-hexahydro-6h-benzofuro(3a,-3,2-ef) (2)benzazepins
GB9506843D0 (en) * 1995-04-03 1995-05-24 Chiroscience Ltd Oxidative process and products thereof
PT819108E (pt) * 1995-04-06 2002-02-28 Janssen Pharmaceutica Nv Processo para a preparacao de derivados de galantamina por reducao assimetrica

Also Published As

Publication number Publication date
DK0819112T3 (da) 2002-04-29
DE69619230D1 (de) 2002-03-21
DE69619230T2 (de) 2002-09-19
GB9506843D0 (en) 1995-05-24
CA2215633A1 (en) 1996-10-10
CA2215633C (en) 2007-07-31
ZA962677B (en) 1997-04-03
US6084094A (en) 2000-07-04
ES2171661T3 (es) 2002-09-16
PT819112E (pt) 2002-07-31
AU5159596A (en) 1996-10-23
AU716794B2 (en) 2000-03-09
EP0819112A1 (de) 1998-01-21
EP0819112B1 (de) 2002-02-13
US6271371B1 (en) 2001-08-07
WO1996031458A1 (en) 1996-10-10

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Legal Events

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UEP Publication of translation of european patent specification