ATE213228T1 - Oxidatives verfahren zur herstellung von narwedin-derivaten - Google Patents

Oxidatives verfahren zur herstellung von narwedin-derivaten

Info

Publication number
ATE213228T1
ATE213228T1 AT96908286T AT96908286T ATE213228T1 AT E213228 T1 ATE213228 T1 AT E213228T1 AT 96908286 T AT96908286 T AT 96908286T AT 96908286 T AT96908286 T AT 96908286T AT E213228 T1 ATE213228 T1 AT E213228T1
Authority
AT
Austria
Prior art keywords
producing
compound
formula
oxidative process
narwedine
Prior art date
Application number
AT96908286T
Other languages
English (en)
Inventor
James Henshilwood
Nicholas Bernard Johnson
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE213228T1 publication Critical patent/ATE213228T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
AT96908286T 1995-04-03 1996-04-02 Oxidatives verfahren zur herstellung von narwedin-derivaten ATE213228T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9506843.3A GB9506843D0 (en) 1995-04-03 1995-04-03 Oxidative process and products thereof
PCT/GB1996/000815 WO1996031458A1 (en) 1995-04-03 1996-04-02 Oxidative process for preparing narwedine derivatives

Publications (1)

Publication Number Publication Date
ATE213228T1 true ATE213228T1 (de) 2002-02-15

Family

ID=10772408

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96908286T ATE213228T1 (de) 1995-04-03 1996-04-02 Oxidatives verfahren zur herstellung von narwedin-derivaten

Country Status (12)

Country Link
US (2) US6084094A (de)
EP (1) EP0819112B1 (de)
AT (1) ATE213228T1 (de)
AU (1) AU716794B2 (de)
CA (1) CA2215633C (de)
DE (1) DE69619230T2 (de)
DK (1) DK0819112T3 (de)
ES (1) ES2171661T3 (de)
GB (1) GB9506843D0 (de)
PT (1) PT819112E (de)
WO (1) WO1996031458A1 (de)
ZA (1) ZA962677B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9506843D0 (en) * 1995-04-03 1995-05-24 Chiroscience Ltd Oxidative process and products thereof
EP1670767B2 (de) * 2003-09-26 2014-10-29 ScinoPharm Taiwan, Ltd. Optische trennung eines narwedinamidderivats
US20050142193A1 (en) * 2003-12-31 2005-06-30 Lijuan Tang Galantamine formulations
CA2551946A1 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Immediate, controlled and sustained release formulations of galantamine
ATE459627T1 (de) * 2005-05-03 2010-03-15 Medichem Sa Synthesen und herstellungen von narwedin und verwandten neuen verbindungen
CA2683098C (en) 2007-04-12 2014-03-18 Scinopharm Taiwan Ltd. Process for making galantamine
SG11201607364RA (en) 2014-03-07 2016-10-28 Dna Genotek Inc Composition and method for stabilizing nucleic acids in biological samples
CN104592243B (zh) * 2014-12-19 2016-08-24 北京大学 加兰他敏和力克拉敏的不对称合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL122665B1 (en) * 1978-11-21 1982-08-31 Edinen Zentar Chim Process for preparing novel dienones of narvedine type and their derivatives
US4290862A (en) * 1979-11-14 1981-09-22 Edinen Centar P Chimia Method for the preparation of narwedine-type enones
KR100195399B1 (ko) 1987-05-04 1999-06-15 보니데이비스 알쯔하이머 병 치료용 의약
AT401058B (de) 1994-10-21 1996-06-25 Waldheim Pharmazeutika Gmbh Verfahren zum herstellen von derivaten des 4a,5, 9,10,11,12,-hexahydro-6h-benzofuro(3a,-3,2-ef) (2)benzazepins
GB9506843D0 (en) * 1995-04-03 1995-05-24 Chiroscience Ltd Oxidative process and products thereof
US6018043A (en) * 1995-04-06 2000-01-25 Janssen Pharmaceutica, N.V. Process for preparing galanthamine derivatives by asymmetric reduction

Also Published As

Publication number Publication date
ES2171661T3 (es) 2002-09-16
EP0819112A1 (de) 1998-01-21
US6084094A (en) 2000-07-04
DE69619230T2 (de) 2002-09-19
GB9506843D0 (en) 1995-05-24
AU5159596A (en) 1996-10-23
CA2215633C (en) 2007-07-31
EP0819112B1 (de) 2002-02-13
US6271371B1 (en) 2001-08-07
DE69619230D1 (de) 2002-03-21
ZA962677B (en) 1997-04-03
DK0819112T3 (da) 2002-04-29
CA2215633A1 (en) 1996-10-10
WO1996031458A1 (en) 1996-10-10
PT819112E (pt) 2002-07-31
AU716794B2 (en) 2000-03-09

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Legal Events

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UEP Publication of translation of european patent specification