ATE213492T1 - Verfahren zur herstellung von racemisch sertralin - Google Patents

Verfahren zur herstellung von racemisch sertralin

Info

Publication number
ATE213492T1
ATE213492T1 AT99420077T AT99420077T ATE213492T1 AT E213492 T1 ATE213492 T1 AT E213492T1 AT 99420077 T AT99420077 T AT 99420077T AT 99420077 T AT99420077 T AT 99420077T AT E213492 T1 ATE213492 T1 AT E213492T1
Authority
AT
Austria
Prior art keywords
sertraline
dichlorophenyl
racemixed
producing
racemic
Prior art date
Application number
AT99420077T
Other languages
English (en)
Inventor
Patrick Bigot
Original Assignee
Catalys
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Catalys filed Critical Catalys
Application granted granted Critical
Publication of ATE213492T1 publication Critical patent/ATE213492T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/62Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/24Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds
    • C07C209/28Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds by reduction with other reducing agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/08Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • C07C233/14Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT99420077T 1998-04-01 1999-03-26 Verfahren zur herstellung von racemisch sertralin ATE213492T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9804270A FR2777000B1 (fr) 1998-04-01 1998-04-01 Procede de preparation de la sertraline racemique

Publications (1)

Publication Number Publication Date
ATE213492T1 true ATE213492T1 (de) 2002-03-15

Family

ID=9524917

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99420077T ATE213492T1 (de) 1998-04-01 1999-03-26 Verfahren zur herstellung von racemisch sertralin

Country Status (8)

Country Link
US (1) US6262308B1 (de)
EP (1) EP0947499B1 (de)
AT (1) ATE213492T1 (de)
DE (1) DE69900892T2 (de)
DK (1) DK0947499T3 (de)
ES (1) ES2172296T3 (de)
FR (1) FR2777000B1 (de)
PT (1) PT947499E (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1031500A (en) * 1998-11-03 2000-05-22 Dandy A/S Sucrose fatty acid esters for use as increased release of active ingredients
DK174219B1 (da) * 1999-10-27 2002-09-30 Gea Farmaceutisk Fabrik As Forbedret syntese af racemisk sertralin
US6723878B2 (en) 2001-06-15 2004-04-20 Orion Corporation Fermion Method for preparing sertraline
EP1503978A1 (de) * 2002-05-10 2005-02-09 Jiri Stohandl Verfahren zur herstellung von sertralin
WO2005000786A1 (en) 2003-05-23 2005-01-06 Transform Pharmaceuticals, Inc. Sertraline compositions
KR101340270B1 (ko) 2011-11-10 2013-12-10 보령제약 주식회사 (+)-시스-서트랄린의 선택적인 제조방법
CN109810004A (zh) * 2017-11-20 2019-05-28 浙江京新药业股份有限公司 一种盐酸舍曲林杂质的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536518A (en) * 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
FR2632633B1 (fr) 1988-06-08 1991-04-05 Delalande Sa Procede de preparation de 4-aryl-1-tetralones
GB9114948D0 (en) * 1991-07-11 1991-08-28 Pfizer Ltd Process for preparing sertraline intermediates
GB9114947D0 (en) * 1991-07-11 1991-08-28 Pfizer Ltd Process for preparing sertraline

Also Published As

Publication number Publication date
PT947499E (pt) 2002-07-31
DE69900892D1 (de) 2002-03-28
ES2172296T3 (es) 2002-09-16
DK0947499T3 (da) 2002-06-10
EP0947499A2 (de) 1999-10-06
FR2777000A1 (fr) 1999-10-08
EP0947499B1 (de) 2002-02-20
FR2777000B1 (fr) 2002-09-27
DE69900892T2 (de) 2002-09-19
US6262308B1 (en) 2001-07-17
EP0947499A3 (de) 2000-02-23

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Legal Events

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REN Ceased due to non-payment of the annual fee