ATE216247T1 - Aromatische oligomere verbindungen als imitatoren bioaktives makromoleküle - Google Patents
Aromatische oligomere verbindungen als imitatoren bioaktives makromoleküleInfo
- Publication number
- ATE216247T1 ATE216247T1 AT92912715T AT92912715T ATE216247T1 AT E216247 T1 ATE216247 T1 AT E216247T1 AT 92912715 T AT92912715 T AT 92912715T AT 92912715 T AT92912715 T AT 92912715T AT E216247 T1 ATE216247 T1 AT E216247T1
- Authority
- AT
- Austria
- Prior art keywords
- oligomeric compounds
- disorders
- immittators
- treatment
- bioactive macromolecules
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 230000000975 bioactive effect Effects 0.000 title 1
- 229920002521 macromolecule Polymers 0.000 title 1
- 102000016387 Pancreatic elastase Human genes 0.000 abstract 1
- 108010067372 Pancreatic elastase Proteins 0.000 abstract 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 210000002808 connective tissue Anatomy 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 230000000055 hyoplipidemic effect Effects 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 230000002503 metabolic effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001537 neural effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 210000000329 smooth muscle myocyte Anatomy 0.000 abstract 1
- 230000008354 tissue degradation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G8/00—Condensation polymers of aldehydes or ketones with phenols only
- C08G8/04—Condensation polymers of aldehydes or ketones with phenols only of aldehydes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Polymers & Plastics (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
- Polyamides (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70306191A | 1991-05-20 | 1991-05-20 | |
| PCT/US1992/004274 WO1992020350A1 (en) | 1991-05-20 | 1992-05-20 | Aromatic oligomeric compounds useful as mimics of bioactive macromolecules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE216247T1 true ATE216247T1 (de) | 2002-05-15 |
Family
ID=24823810
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92912715T ATE216247T1 (de) | 1991-05-20 | 1992-05-20 | Aromatische oligomere verbindungen als imitatoren bioaktives makromoleküle |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0585371B1 (de) |
| AT (1) | ATE216247T1 (de) |
| AU (1) | AU2010792A (de) |
| DE (1) | DE69232557T2 (de) |
| DK (1) | DK0585371T3 (de) |
| ES (1) | ES2174834T3 (de) |
| MX (1) | MX9202389A (de) |
| WO (1) | WO1992020350A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE433964T1 (de) | 2000-12-28 | 2009-07-15 | Takeda Pharmaceutical | Alkansäurederivate, verfahren zu deren herstellung und deren verwendung |
| EP1394154A4 (de) | 2001-03-23 | 2005-05-18 | Takeda Pharmaceutical | Fünfgliedriges heterocyclisches alkansäurederivat |
| WO2005026150A1 (en) | 2003-09-16 | 2005-03-24 | Astrazeneca Ab | Quinazoline derivatives as tyrosine kinase inhibitors |
| EP1928237A4 (de) | 2005-09-02 | 2011-03-09 | Abbott Lab | Neue heterocyclen auf imidazo-basis |
| CN112135825A (zh) | 2018-03-13 | 2020-12-25 | 夏尔人类遗传性治疗公司 | 血浆激肽释放酶抑制剂及其用途 |
| CN114728962B (zh) | 2019-09-18 | 2025-09-19 | 武田药品工业有限公司 | 血浆激肽释放酶抑制剂及其用途 |
| WO2021055589A1 (en) | 2019-09-18 | 2021-03-25 | Shire Human Genetic Therapies, Inc. | Heteroaryl plasma kallikrein inhibitors |
| CA3251849A1 (en) | 2022-03-02 | 2023-09-07 | Horizon Therapeutics Ireland Dac | METHOD FOR MANUFACTURING A CRYSTALLINE EDG-2 RECEPTOR ANTAGONIST |
| AU2023228377A1 (en) | 2022-03-02 | 2024-08-08 | Horizon Therapeutics Ireland Dac | Treatment of systemic sclerosis and idiopathic pulmonary fibrosis |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2323481A (en) * | 1939-03-14 | 1943-07-06 | Du Pont | Chemical process and composition |
| US2910484A (en) * | 1957-05-09 | 1959-10-27 | Ciba Pharm Prod Inc | Polyhydric-aldehyde condensation products |
| US4604404A (en) * | 1985-04-03 | 1986-08-05 | A. H. Robins Company, Inc. | Antiviral sulfonated naphthalene formaldehyde condensation polymers |
| IL95353A (en) * | 1989-08-14 | 1995-01-24 | Rhone Poulenc Rorer Int | Pharmaceutical preparations containing aromatic polymers |
| JPH05508665A (ja) * | 1989-11-22 | 1993-12-02 | ローヌー プーラン ローラー インターナショナル（ホウルディングス）インコーポレイテッド | アルキル―またはヘテロアルキル―アリール主鎖を有するポリマー及びこれらのポリマーを含む医薬組成物 |
| FR2672214A1 (fr) * | 1991-01-31 | 1992-08-07 | Rhone Poulenc Rorer Sa | Application de polymeres biologiquement actifs, pour l'obtention d'un medicament pour le traitement d'infections a retrovirus. |
-
1992
- 1992-05-20 AT AT92912715T patent/ATE216247T1/de not_active IP Right Cessation
- 1992-05-20 ES ES92912715T patent/ES2174834T3/es not_active Expired - Lifetime
- 1992-05-20 WO PCT/US1992/004274 patent/WO1992020350A1/en not_active Ceased
- 1992-05-20 AU AU20107/92A patent/AU2010792A/en not_active Abandoned
- 1992-05-20 DE DE69232557T patent/DE69232557T2/de not_active Expired - Fee Related
- 1992-05-20 DK DK92912715T patent/DK0585371T3/da active
- 1992-05-20 EP EP92912715A patent/EP0585371B1/de not_active Expired - Lifetime
- 1992-05-20 MX MX9202389A patent/MX9202389A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX9202389A (es) | 1993-08-01 |
| DE69232557D1 (de) | 2002-05-23 |
| WO1992020350A1 (en) | 1992-11-26 |
| EP0585371A4 (en) | 1994-07-13 |
| EP0585371A1 (de) | 1994-03-09 |
| AU2010792A (en) | 1992-12-30 |
| DK0585371T3 (da) | 2002-08-12 |
| DE69232557T2 (de) | 2002-10-24 |
| ES2174834T3 (es) | 2002-11-16 |
| EP0585371B1 (de) | 2002-04-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |