ATE21625T1 - Ubidecarenone enthaltende, eingekapselte liposome. - Google Patents

Ubidecarenone enthaltende, eingekapselte liposome.

Info

Publication number: ATE21625T1
Authority: AT; Austria
Prior art keywords: ubidecarenone; containing encapsulated; encapsulated liposomes; liposome; liposomes
Prior art date: 1982-05-19

Application number

AT83104967T

Other languages

English (en)

Inventor

Masahiro Takada

Yatabe-Machi

Teruaki Yuzuriha

Kouichi Katayama

Junzo Sunamoto

Original Assignee

Eisai Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-05-19

Filing date

1983-05-19

Publication date

1986-09-15

1983-05-19 Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd

1986-09-15 Application granted granted Critical

1986-09-15 Publication of ATE21625T1 publication Critical patent/ATE21625T1/de

Links

ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 title abstract 4
ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 title abstract 4
235000017471 coenzyme Q10 Nutrition 0.000 title abstract 4
239000002502 liposome Substances 0.000 title abstract 4
229960004747 ubidecarenone Drugs 0.000 title abstract 4
235000014113 dietary fatty acids Nutrition 0.000 abstract 1
229930195729 fatty acid Natural products 0.000 abstract 1
239000000194 fatty acid Substances 0.000 abstract 1
210000003734 kidney Anatomy 0.000 abstract 1
210000004072 lung Anatomy 0.000 abstract 1
239000012528 membrane Substances 0.000 abstract 1
229920001282 polysaccharide Polymers 0.000 abstract 1
239000005017 polysaccharide Substances 0.000 abstract 1
-1 polysaccharide fatty acid ester Chemical class 0.000 abstract 1
210000000952 spleen Anatomy 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Dispersion Chemistry (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT83104967T 1982-05-19 1983-05-19 Ubidecarenone enthaltende, eingekapselte liposome. ATE21625T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP57082993A JPS58201711A (ja)	1982-05-19	1982-05-19	ユビデカレノン含有リポソ−ム被覆体
EP83104967A EP0094692B1 (de)	1982-05-19	1983-05-19	Ubidecarenone enthaltende, eingekapselte Liposome

Publications (1)

Publication Number	Publication Date
ATE21625T1 true ATE21625T1 (de)	1986-09-15

Family

ID=13789741

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT83104967T ATE21625T1 (de)	1982-05-19	1983-05-19	Ubidecarenone enthaltende, eingekapselte liposome.

Country Status (8)

Country	Link
US (1)	US4636381A (de)
EP (1)	EP0094692B1 (de)
JP (1)	JPS58201711A (de)
KR (1)	KR840004512A (de)
AT (1)	ATE21625T1 (de)
CA (1)	CA1214392A (de)
DE (1)	DE3365604D1 (de)
ES (1)	ES8407095A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH661438A5 (it) *	1984-04-09	1987-07-31	Seuref Ag	Composizioni farmaceutiche ad azione antianossica e metabolica cerebrale.
US4880635B1 (en) *	1984-08-08	1996-07-02	Liposome Company	Dehydrated liposomes
JPS61112021A (ja) *	1984-11-06	1986-05-30	Dai Ichi Seiyaku Co Ltd	脂質膜構造体
US4883670A (en) *	1986-10-23	1989-11-28	Arval S.P.A.	Cosmetic preparations containing ubidecarenones
US5320906A (en) *	1986-12-15	1994-06-14	Vestar, Inc.	Delivery vehicles with amphiphile-associated active ingredient
JPS63313724A (ja) *	1987-06-16	1988-12-21	Eisai Co Ltd	シアル酸修飾多糖被覆リポソ−ム
US5705187A (en) *	1989-12-22	1998-01-06	Imarx Pharmaceutical Corp.	Compositions of lipids and stabilizing materials
US6461593B1 (en) *	1992-02-19	2002-10-08	Biomedical And Clinical Research	Therapy with coenzyme Q10 to reduce subgingival microorganisms in patients with periodontal disease
DE4433101A1 (de) *	1994-09-16	1996-03-21	Bauer Kurt Heinz Prof Dr	Wasserlösliche Dextranfettsäureester und ihre Verwendung als Solubilisatoren
EP0869773B1 (de) *	1995-12-15	2004-03-24	National Research Council Of Canada	Archaeoliposome, koenzym q10 enthaltende archaeoliposome und koenzym q10 enthaltende liposome als adjuvans und wirkstoffabgabevehikel
US5891465A (en) *	1996-05-14	1999-04-06	Biozone Laboratories, Inc.	Delivery of biologically active material in a liposomal formulation for administration into the mouth
AU9221698A (en) *	1997-09-04	1999-03-22	Biozone Laboratories, Inc.	Oral liposomal delivery system
US20010003580A1 (en)	1998-01-14	2001-06-14	Poh K. Hui	Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
ID29429A (id) *	1999-01-15	2001-08-30	Cooperetieve Verkoop En Produc	Turunan-turuna pati hidrofobik
US6710038B1 (en)	1999-12-14	2004-03-23	Kibun Food Chemifa Co., Ltd.	Emulsification method using propylene glycol hyaluronate
US8252322B2 (en) *	2003-06-03	2012-08-28	Corn Products Development, Inc.	Delivery system with increased bioavailability
ES2809302T3 (es)	2004-01-22	2021-03-03	Univ Miami	Formulaciones de coenzima Q10 para tratar tumores sólidos mediante administración intravenosa
JP2006137684A (ja) *	2004-11-10	2006-06-01	Nippon Fine Chem Co Ltd	リポソーム前駆体の製造方法
JP5140913B2 (ja) *	2005-09-14	2013-02-13	日油株式会社	コエンザイムｑ１０含有化粧料用リポソーム
CA2977089A1 (en)	2006-05-02	2007-11-15	University Of Miami	Topical co-enzyme q10 formulations and treatment of pain, fatigue and wounds
CA2680825C (en)	2007-03-22	2013-10-29	Cytotech Labs, Llc	Topical formulations having enhanced bioavailability
US20110142914A1 (en) *	2007-12-06	2011-06-16	Cytotech Labs, Llc	Inhalable compositions having enhanced bioavailability
AU2009233785B2 (en)	2008-04-11	2015-08-20	Berg Llc	Methods and use of inducing apoptosis in cancer cells
WO2010021034A1 (ja) *	2008-08-20	2010-02-25	昭和電工株式会社	皮膚外用剤
AU2010247800A1 (en)	2009-05-11	2011-12-15	Berg Llc	Methods for the diagnosis of metabolic disorders using epimetabolic shifters, multidimensional intracellular molecules, or environmental influencers
CN105168135A (zh)	2010-03-12	2015-12-23	博格有限责任公司	辅酶Q10(CoQ10)的静脉内制剂及其使用方法
CA2832324C (en)	2011-04-04	2022-03-15	Berg Llc	Methods of treating central nervous system tumors
US10973763B2 (en)	2011-06-17	2021-04-13	Berg Llc	Inhalable pharmaceutical compositions
SG10201903112WA (en)	2013-04-08	2019-05-30	Berg Llc	Treatment of cancer using coenzyme q10 combination therapies
WO2015008301A1 (en) *	2013-07-17	2015-01-22	Council Of Scientific & Industrial Research	Pharmaceutical composition for the treatment of diminution of bone tissue
KR102370843B1 (ko)	2013-09-04	2022-03-04	버그 엘엘씨	코엔자임 q10의 연속주입에 의한 암치료 방법
WO2017087576A1 (en)	2015-11-16	2017-05-26	Berg Llc	Methods of treatment of temozolomide-resistant glioma using coenzyme q10
DK3634391T3 (da)	2017-05-17	2025-03-31	Bpgbio Inc	Anvendelse af coenzym q10-formuleringer i behandlingen og forebyggelsen af epidermolysis bullosa
CN113262310A (zh) *	2021-03-02	2021-08-17	宿迁市第一人民医院	一种普鲁兰多糖修饰的人参皂苷Rg3纳米结构脂质载体及其制作方法
WO2024190865A1 (ja) *	2023-03-15	2024-09-19	ユナイテッド・イミュニティ株式会社	脂質粒子

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2640707C3 (de) *	1976-09-10	1980-01-24	Karl Dr.Med. 7302 Ostfildern Theurer	Verfahren zur Herstellung von Arzneipräparaten mit einem Gehalt an von im Darm resorbierbaren Protein und Peptidlösungen
US4310505A (en) *	1979-11-08	1982-01-12	California Institute Of Technology	Lipid vesicles bearing carbohydrate surfaces as lymphatic directed vehicles for therapeutic and diagnostic substances
FR2472384A1 (fr) *	1979-12-27	1981-07-03	Sederma Sa	Utilisation en cosmetologie de complexes naturels constitues d'ubiquinones et de phospholipides
JPS5849311A (ja) *	1981-09-18	1983-03-23	Eisai Co Ltd	安全なるリポソ−ムの製造法

1982
- 1982-05-19 JP JP57082993A patent/JPS58201711A/ja active Pending
1983
- 1983-05-18 ES ES522512A patent/ES8407095A1/es not_active Expired
- 1983-05-18 CA CA000428447A patent/CA1214392A/en not_active Expired
- 1983-05-19 KR KR1019830002210A patent/KR840004512A/ko not_active Ceased
- 1983-05-19 DE DE8383104967T patent/DE3365604D1/de not_active Expired
- 1983-05-19 AT AT83104967T patent/ATE21625T1/de not_active IP Right Cessation
- 1983-05-19 US US06/497,255 patent/US4636381A/en not_active Expired - Fee Related
- 1983-05-19 EP EP83104967A patent/EP0094692B1/de not_active Expired

Also Published As

Publication number	Publication date
JPS58201711A (ja)	1983-11-24
EP0094692B1 (de)	1986-08-27
ES522512A0 (es)	1984-09-01
KR840004512A (ko)	1984-10-22
CA1214392A (en)	1986-11-25
EP0094692A1 (de)	1983-11-23
US4636381A (en)	1987-01-13
DE3365604D1 (en)	1986-10-02
ES8407095A1 (es)	1984-09-01

Legal Events

Date	Code	Title	Description
1986-11-15	UEP	Publication of translation of european patent specification
1988-08-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE21625T1 (de)	1986-09-15	Ubidecarenone enthaltende, eingekapselte liposome.
NO833992L (no)	1984-05-09	Minimalisering av virkningene av fiskehalesvingninger i vindturbiner
AU542020B2 (en)	1985-01-31	Improvements in or relating to pumps
AU4384479A (en)	1979-08-09	Diffusion and oxygenation
GB2102083B (en)	1983-06-08	Improvements in or relating to bearings
AU525310B2 (en)	1982-10-28	Improvements in and relating to the positioning of the end of an underwater flowline
IT8147509A0 (it)	1981-01-05	Perfezionamento nelle composizioni acquose contenenti enzimi stabilizzati
FI870645A0 (fi)	1987-02-16	Behaollare foer lagring av flytande media i vatten.
JPS5638573A (en)	1981-04-13	Method of running pump turbine
JPS525568A (en)	1977-01-17	Driving method of indication
ZA787315B (en)	1979-12-27	Axial flow and partly axial flow pumps
FI812966L (fi)	1982-03-24	Anordning vid taetningar t ex foer axlarna i centrifugalpumpar
SU700868A1 (ru)	1979-11-30	Преобразователь напр жени треугольной формы в синусоидальную
AU524892B2 (en)	1982-10-07	Axial-flow and partly axial-flow pumps
AU527511B2 (en)	1983-03-10	Improvements in or relating to anchors
DE2964399D1 (en)	1983-02-03	Improvements in or relating to drive and brake assemblies
JPS51120275A (en)	1976-10-21	Humidity transducer and its production method
JPS54120196A (en)	1979-09-18	Impeller that simultaneously improve propulsion efficiency and stability of shipping
SE8505688D0 (sv)	1985-12-02	Rundjern att fora in i listen pa husvagnen
BG27986A1 (en)	1980-02-25	Method of determination the hydrolysis stability of lipids and the prohydrolysis effect of the lipase and nonlipase complex
DD137370A1 (de)	1979-08-29	Schalung zur herstellung von runden aussparungen im unterbeton
AU89225S (en)	1984-07-12	A pallet
FI843235A7 (fi)	1986-02-17	Keskipakoisvesipumppu ja keskipakoisvesivoimala ilmanpaineella.
KR850005777A (ko)	1985-09-26	신포접화합물의 제조방법
AU6770481A (en)	1981-08-31	Improvements in and relating to the joining of tubes