ATE216273T1 - Abgabevorrichtungen mit gepulstem effekt - Google Patents

Abgabevorrichtungen mit gepulstem effekt

Info

Publication number
ATE216273T1
ATE216273T1 AT94303254T AT94303254T ATE216273T1 AT E216273 T1 ATE216273 T1 AT E216273T1 AT 94303254 T AT94303254 T AT 94303254T AT 94303254 T AT94303254 T AT 94303254T AT E216273 T1 ATE216273 T1 AT E216273T1
Authority
AT
Austria
Prior art keywords
orifice
dispensing devices
resilient material
beneficial agent
effect dispensing
Prior art date
Application number
AT94303254T
Other languages
English (en)
Inventor
Stephen M Balaban
James B Pike
Jonathon P Smith
Clifton A Baile
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ATE216273T1 publication Critical patent/ATE216273T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons pressurised by means of pistons
    • A61M5/14526—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons pressurised by means of pistons the piston being actuated by fluid pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons
    • A61M2005/14513—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons with secondary fluid driving or regulating the infusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Fluid Mechanics (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Fluid-Pressure Circuits (AREA)
  • Finish Polishing, Edge Sharpening, And Grinding By Specific Grinding Devices (AREA)
  • Grinding-Machine Dressing And Accessory Apparatuses (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Prostheses (AREA)
  • Toys (AREA)
  • Refuse Collection And Transfer (AREA)
AT94303254T 1993-05-05 1994-05-05 Abgabevorrichtungen mit gepulstem effekt ATE216273T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/058,151 US5308348A (en) 1992-02-18 1993-05-05 Delivery devices with pulsatile effect

Publications (1)

Publication Number Publication Date
ATE216273T1 true ATE216273T1 (de) 2002-05-15

Family

ID=22015019

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94303254T ATE216273T1 (de) 1993-05-05 1994-05-05 Abgabevorrichtungen mit gepulstem effekt

Country Status (5)

Country Link
US (1) US5308348A (de)
EP (1) EP0627231B1 (de)
AT (1) ATE216273T1 (de)
DE (1) DE69430406T2 (de)
ES (1) ES2171434T3 (de)

Families Citing this family (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5728088A (en) * 1988-12-13 1998-03-17 Alza Corporation Osmotic system for delivery of fluid-sensitive somatotropins to bovine animals
US5672167A (en) * 1990-05-21 1997-09-30 Recordati Corporation Controlled release osmotic pump
US5658269A (en) * 1990-10-29 1997-08-19 The Procter & Gamble Company Extensible absorbent articles
US5456679A (en) * 1992-02-18 1995-10-10 Alza Corporation Delivery devices with pulsatile effect
US5498255A (en) * 1993-08-17 1996-03-12 Alza Corporation Osmotic device for protracted pulsatile delivery of agent
US5836940A (en) * 1994-10-25 1998-11-17 Latis, Inc. Photoacoustic drug delivery
US5817144A (en) * 1994-10-25 1998-10-06 Latis, Inc. Method for contemporaneous application OF laser energy and localized pharmacologic therapy
US5690952A (en) * 1995-06-07 1997-11-25 Judy A. Magruder et al. Implantable system for delivery of fluid-sensitive agents to animals
US5837284A (en) 1995-12-04 1998-11-17 Mehta; Atul M. Delivery of multiple doses of medications
US5922736A (en) * 1995-12-04 1999-07-13 Celegene Corporation Chronic, bolus administration of D-threo methylphenidate
US6486177B2 (en) * 1995-12-04 2002-11-26 Celgene Corporation Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate
US6132420A (en) * 1996-02-02 2000-10-17 Alza Corporation Osmotic delivery system and method for enhancing start-up and performance of osmotic delivery systems
US6395292B2 (en) 1996-02-02 2002-05-28 Alza Corporation Sustained delivery of an active agent using an implantable system
AU778902B2 (en) * 1996-02-02 2004-12-23 Intarcia Therapeutics, Inc. A device for an active agent in a fluid environment of use
US6156331A (en) * 1996-02-02 2000-12-05 Alza Corporation Sustained delivery of an active agent using an implantable system
US6261584B1 (en) 1996-02-02 2001-07-17 Alza Corporation Sustained delivery of an active agent using an implantable system
DE69720190T2 (de) * 1996-02-02 2003-12-11 Alza Corp Implantierbares system mit verzögerter freisetzung von leuprolid
ATE318580T1 (de) * 1996-12-20 2006-03-15 Alza Corp Gelzusammensetzungen und verfahren
ZA981610B (en) * 1997-03-24 1999-08-26 Alza Corp Self adjustable exit port.
EP1325741B1 (de) * 1997-03-24 2007-06-06 Alza Corporation Implantierbare Verabreichungsvorrichtung mit einer selbstjustierenden Ausgangsöffnung
US6962997B1 (en) * 1997-05-22 2005-11-08 Celgene Corporation Process and intermediates for resolving piperidyl acetamide steroisomers
MY125870A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system flow modulator apparatus and method
MY125849A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system, osmotic delivery system semipermeable body assembly, and method for controlling delivery rate of beneficial agents from osmotic delivery systems
AU734727B2 (en) 1997-12-05 2001-06-21 Interag Improvements in and/or relating to delivery devices and their use
EP1041968B1 (de) * 1997-12-29 2004-03-03 Alza Corporation Osmotisches verabreichungssystem mit stöpselrückhaltemechanismus
ATE342051T1 (de) * 1997-12-30 2006-11-15 Alza Corp Verabreichungssystem für wirkstoffe mit einem membranstöpsel
AU1937099A (en) 1997-12-31 1999-07-19 Alza Corporation Osmotic drug delivery monitoring system and method
US6099859A (en) * 1998-03-20 2000-08-08 Andrx Pharmaceuticals, Inc. Controlled release oral tablet having a unitary core
US6099862A (en) * 1998-08-31 2000-08-08 Andrx Corporation Oral dosage form for the controlled release of a biguanide and sulfonylurea
US6322819B1 (en) 1998-10-21 2001-11-27 Shire Laboratories, Inc. Oral pulsed dose drug delivery system
WO2000048662A1 (en) * 1999-02-16 2000-08-24 Prismedical Corporation Single dose delivery device
WO2000059481A1 (en) * 1999-04-06 2000-10-12 Pharmaquest Ltd. PHARMACEUTICAL DOSAGE FORM FOR PULSATILE DELIVERY OF d-threo-METHYLPHENIDATE AND A SECOND CNS STIMULANT
US20030170181A1 (en) * 1999-04-06 2003-09-11 Midha Kamal K. Method for preventing abuse of methylphenidate
AU773354B2 (en) 1999-12-21 2004-05-20 Intarcia Therapeutics, Inc. Valve for osmotic devices
US20030211974A1 (en) * 2000-03-21 2003-11-13 Brodbeck Kevin J. Gel composition and methods
US20060034922A1 (en) * 2000-11-03 2006-02-16 Andrx Labs, Llc Controlled release metformin compositions
US6790459B1 (en) 2000-11-03 2004-09-14 Andrx Labs, Llc Methods for treating diabetes via administration of controlled release metformin
US6866866B1 (en) * 2000-11-03 2005-03-15 Andrx Labs, Llc Controlled release metformin compositions
US7163688B2 (en) * 2001-06-22 2007-01-16 Alza Corporation Osmotic implant with membrane and membrane retention means
SG106631A1 (en) * 2001-08-31 2004-10-29 Agency Science Tech & Res Liquid delivering device
ATE507816T1 (de) * 2001-11-14 2011-05-15 Durect Corp Injizierbare depotzusammensetzungen und deren verwendung
US20070196415A1 (en) * 2002-11-14 2007-08-23 Guohua Chen Depot compositions with multiple drug release rate controls and uses thereof
AU2002359407B2 (en) * 2001-11-14 2008-02-28 Durect Corporation Catheter injectable depot compositions and uses thereof
NZ533642A (en) * 2001-11-21 2006-12-22 Alza Corp Osmotic delivery device having a two-way valve and dynamically self-adjusting flow channel
GB2403421B (en) * 2002-04-08 2005-07-13 Rosemount Inc Implantable pressure-activated micro-valve
US6974587B2 (en) * 2002-05-08 2005-12-13 Aircom Manufacturing, Inc. Intraruminal device
AU2003241537A1 (en) * 2002-05-23 2003-12-12 Andrx Corporation Biguanide formulations
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
TWI353854B (en) 2002-06-25 2011-12-11 Alza Corp Short duration depot formulations
WO2004002565A1 (en) * 2002-06-26 2004-01-08 Alza Corporation Minimally compliant, volume efficient piston for osmotic drug delivery systems
CN1684663A (zh) * 2002-07-31 2005-10-19 阿尔萨公司 可注射的多模式聚合物储库组合物以及其用途
WO2004012703A1 (en) * 2002-07-31 2004-02-12 Alza Corporation Injectable depot compositions and uses thereof
US6913768B2 (en) * 2002-09-24 2005-07-05 Shire Laboratories, Inc. Sustained release delivery of amphetamine salts
US7368126B2 (en) * 2002-11-06 2008-05-06 Guohua Chen Controlled release depot formulations
US7014636B2 (en) * 2002-11-21 2006-03-21 Alza Corporation Osmotic delivery device having a two-way valve and a dynamically self-adjusting flow channel
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
RU2005133427A (ru) * 2003-03-31 2006-04-27 Алза Корпорейшн (Us) Безводные однофазные носители и препараты с использованием таких носителей
JP2006521898A (ja) * 2003-03-31 2006-09-28 アルザ・コーポレーション 浸透送り出しシステム及び浸透送り出しシステムの始動時間を短縮する方法
US7207982B2 (en) * 2003-03-31 2007-04-24 Alza Corporation Osmotic pump with means for dissipating internal pressure
US6825255B2 (en) * 2003-05-01 2004-11-30 Solutia Incorporated Polyvinyl butyral sheet having antiblocking characteristics
US20070184084A1 (en) * 2003-05-30 2007-08-09 Guohua Chen Implantable elastomeric caprolactone depot compositions and uses thereof
US20050079202A1 (en) * 2003-05-30 2005-04-14 Guohua Chen Implantable elastomeric depot compositions and uses thereof
KR20060121890A (ko) * 2003-11-06 2006-11-29 알자 코포레이션 이식형 삼투 펌프와 함께 사용하기 위한 모듈식 흡수율감소기
US20050239830A1 (en) * 2004-04-26 2005-10-27 Vikram Khetani Methods of diminishing co-abuse potential
US20050266087A1 (en) * 2004-05-25 2005-12-01 Gunjan Junnarkar Formulations having increased stability during transition from hydrophobic vehicle to hydrophilic medium
EP1830648A4 (de) * 2004-12-09 2008-03-12 Celgene Corp Behandlung mit d-threo-methylphenidat
US20060142234A1 (en) * 2004-12-23 2006-06-29 Guohua Chen Injectable non-aqueous suspension
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
ES2812250T3 (es) 2005-11-28 2021-03-16 Marinus Pharmaceuticals Inc Formulaciones de ganaxolona y procedimientos para la preparación y uso de las mismas
EP2020990B1 (de) 2006-05-30 2010-09-22 Intarcia Therapeutics, Inc Zweiteiliger flussmodulator mit einem internen kanal für ein osmotisches ausgabesystem
PL2359808T3 (pl) 2006-08-09 2013-10-31 Intarcia Therapeutics Inc Osmotyczne systemy dostawcze i zespoły tłokowe
WO2008066899A2 (en) 2006-11-28 2008-06-05 Marinus Pharmaceuticals Nanoparticulate formulations and methods for the making and use thereof
EP2157967B1 (de) 2007-04-23 2013-01-16 Intarcia Therapeutics, Inc Suspensionsformulierungen insulinotroper peptide und ihre verwendung
EP2240155B1 (de) 2008-02-13 2012-06-06 Intarcia Therapeutics, Inc Vorrichtungen, formulierungen und verfahren zur freisetzung mehrerer wirkstoffe
USD638538S1 (en) 2009-07-10 2011-05-24 Becton, Dickinson And Company Syringe plunger rod
AU2010277872C1 (en) * 2009-07-31 2017-01-19 Boehringer Ingelheim Animal Health USA Inc. Sustained release capsules
EP3323423B1 (de) 2009-09-28 2020-06-17 Intarcia Therapeutics, Inc Schnelle initiierung und/oder beendigung der verabreichung substantiell stabiler arzneimittel
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
WO2015088990A1 (en) 2013-12-09 2015-06-18 Durect Corporation Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
ES2968262T3 (es) 2015-06-03 2024-05-08 I2O Therapeutics Inc Sistemas de colocación de implantes
KR20240037175A (ko) 2016-05-16 2024-03-21 인타르시아 세라퓨틱스 인코포레이티드 글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
KR20230050474A (ko) 2016-08-11 2023-04-14 오비드 테라퓨틱스 인크. 간질 장애의 치료를 위한 방법 및 조성물
AU2018206539A1 (en) 2017-01-03 2019-07-18 Intarcia Therapeutics, Inc. Methods comprising continuous administration of a GLP-1 receptor agonist and co-administration of a drug
US11083847B2 (en) 2018-01-26 2021-08-10 Becton, Dickinson And Company Flush syringe with flip cap
WO2019147977A1 (en) 2018-01-28 2019-08-01 Becton, Dickinson And Company Pulsatile or resonating flush syringe
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly
US11266662B2 (en) 2018-12-07 2022-03-08 Marinus Pharmaceuticals, Inc. Ganaxolone for use in prophylaxis and treatment of postpartum depression
EP4009982A4 (de) 2019-08-05 2023-08-09 Marinus Pharmaceuticals, Inc. Ganaxolon zur verwendung bei der behandlung von status epilepticus
AU2020395254B2 (en) 2019-12-06 2026-04-02 Marinus Pharmaceuticals, Inc. Ganaxolone for use in treating tuberous sclerosis complex
WO2021146215A1 (en) 2020-01-13 2021-07-22 Durect Corporation Sustained release drug delivery systems with reduced impurities and related methods
CA3203561A1 (en) 2021-01-12 2022-07-21 Adrian Neil Verity Sustained release drug delivery systems and related methods
EP4431142A4 (de) * 2021-11-10 2025-07-30 Terumo Corp Verabreichungsvorrichtung
JPWO2023181996A1 (de) * 2022-03-25 2023-09-28
US12685815B2 (en) 2024-01-02 2026-07-21 Manta MedTech LLC System for drug delivery
EP4684817A1 (de) * 2024-07-23 2026-01-28 Manta MedTech LLC Implantierbare vorrichtung mit kolbenverdrängungsüberwachung

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3760806A (en) * 1971-01-13 1973-09-25 Alza Corp Helical osmotic dispenser with non-planar membrane
GB2092679B (en) * 1980-12-03 1984-12-12 Hepworth Gordon Liquid dispensing apparatus
JPS57163309A (en) * 1981-04-01 1982-10-07 Olympus Optical Co Ltd Capsule apparatus for medical use
US4416659A (en) * 1981-11-09 1983-11-22 Eli Lilly And Company Sustained release capsule for ruminants
US4777049A (en) * 1983-12-01 1988-10-11 Alza Corporation Constant release system with pulsed release
GR851195B (de) * 1984-06-02 1985-11-25 Castex Prod
GB8417202D0 (en) * 1984-07-05 1984-08-08 Norbrook Lab Ltd Drug intermittent release device
US4687423A (en) * 1985-06-07 1987-08-18 Ivac Corporation Electrochemically-driven pulsatile drug dispenser
US4842867A (en) * 1986-05-09 1989-06-27 Alza Corporation Pulsed drug delivery of doxylamine
US4723958A (en) * 1986-05-23 1988-02-09 Merck & Co., Inc. Pulsatile drug delivery system
US4867980A (en) * 1986-10-10 1989-09-19 Coopers Animal Health Australia Limited Heavy density depot
US5023088A (en) * 1987-06-25 1991-06-11 Alza Corporation Multi-unit delivery system
US4957494A (en) * 1987-06-25 1990-09-18 Alza Corporation Multi-layer delivery system
US4874388A (en) * 1987-06-25 1989-10-17 Alza Corporation Multi-layer delivery system
AT391416B (de) * 1988-06-23 1990-10-10 Annemarie Schloegl Ges M B H M Septum fuer implantierbare vorrichtungen zur abgabe von wirkstoffen
US4997420A (en) * 1989-12-28 1991-03-05 Lefevre Robert J Portable drug delivery device including pump with tapered barrel
US5122128A (en) * 1990-03-15 1992-06-16 Alza Corporation Orifice insert for a ruminal bolus
US5059175A (en) * 1990-10-09 1991-10-22 University Of Utah Research Foundation Implantable drug delivery system with piston actuation
US5167625A (en) * 1990-10-09 1992-12-01 Sarcos Group Multiple vesicle implantable drug delivery system
US5196002A (en) * 1990-10-09 1993-03-23 University Of Utah Research Foundation Implantable drug delivery system with piston acutation
AU1569292A (en) * 1991-03-12 1992-10-21 Alza Corporation Space- and stability-efficient delivery device
US5227167A (en) * 1991-06-11 1993-07-13 Alza Corporation Long-term delivery device including hydrophobic loading dose
US5137727A (en) * 1991-06-12 1992-08-11 Alza Corporation Delivery device providing beneficial agent stability
US5209746A (en) * 1992-02-18 1993-05-11 Alza Corporation Osmotically driven delivery devices with pulsatile effect
US5221278A (en) * 1992-03-12 1993-06-22 Alza Corporation Osmotically driven delivery device with expandable orifice for pulsatile delivery effect

Also Published As

Publication number Publication date
EP0627231B1 (de) 2002-04-17
DE69430406T2 (de) 2002-12-05
EP0627231A3 (de) 1995-08-30
EP0627231A2 (de) 1994-12-07
US5308348A (en) 1994-05-03
ES2171434T3 (es) 2002-09-16
DE69430406D1 (de) 2002-05-23

Similar Documents

Publication Publication Date Title
DE69430406D1 (de) Abgabevorrichtungen mit gepulstem Effekt
AU558811B2 (en) Inhalation device
TW270081B (de)
JPS6437384A (en) Preparation vessel for viscous substance
AU3738593A (en) Transport vase for cut flowers
SE8601351D0 (sv) Styrd administration av fysiologiskt aktiva emnen
FR2656928B1 (fr) Dispositif ameliore d'immunotest du type plaquette a plonger, et trousse contenant ce dispositif.
ES2032102T3 (es) Capsula de presion para un recipiente rociador.
NZ516405A (en) Insecticidal liquid bait station
ES2083712T3 (es) Dispositivo de mando de distribucion de un producto, principalmente un producto autoespumante.
ES2048312T3 (es) Procedimiento y dispositivo de regulacion de un caudal de co2 liquido, y aplicacion a un tunel de refrigeracion.
ATE184186T1 (de) Tampon-applikator
FR2314312A1 (fr) Activation physico-chimique de l'eau des douches et des chasses
GB2090529A (en) Thrombosis-prophylactic and curing agent
ES2096500T3 (es) Recipiente de pared flexible deformable del tipo frasco; bolsa o tubo.
DE69623157D1 (de) Tauchbecher zur Behandlung von Zitzen bei Tieren
SE9401681L (sv) För engångsanvändning avsett vätskeabsorberande alster, förfarande och anordning för dess framställning
ES2095648T3 (es) Unidad de cierre.
GR3022920T3 (en) Device for defence against insects.
GB1291526A (en) Blood cleaning device
CO4600680A1 (es) Procedimientos para la prevencion de la degradacion de la proteina c
AR016200A1 (es) El uso de una composicion que comprende uno o mas compuestos que contienen azufre para la fabricacion de un medicamento para aumentar la permeabilidad deltejido corneo humano, y un kit que incluye dicha composicion
MX9303808A (es) Dispositivo para abrir y cerrar automaticamente un recipiente.
ATE36333T1 (de) Hydantoin enthaltende therapeutische mittel.
ES2112684B1 (es) Muñeco perfeccionado para simular acciones fisiologicas con dispositivo sonoro.