ATE216581T1 - Phthalocyaninderivate enthaltender photosensibilisator in der photodynamischen therapie von tumoren - Google Patents

Phthalocyaninderivate enthaltender photosensibilisator in der photodynamischen therapie von tumoren

Info

Publication number
ATE216581T1
ATE216581T1 AT94924921T AT94924921T ATE216581T1 AT E216581 T1 ATE216581 T1 AT E216581T1 AT 94924921 T AT94924921 T AT 94924921T AT 94924921 T AT94924921 T AT 94924921T AT E216581 T1 ATE216581 T1 AT E216581T1
Authority
AT
Austria
Prior art keywords
independently selected
tumors
alkenyl
alkyl
compound
Prior art date
Application number
AT94924921T
Other languages
English (en)
Inventor
Michael John Cook
David Andrew Russel
Original Assignee
Qinetiq Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qinetiq Ltd filed Critical Qinetiq Ltd
Application granted granted Critical
Publication of ATE216581T1 publication Critical patent/ATE216581T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Light Receiving Elements (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Weting (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT94924921T 1993-08-27 1994-08-24 Phthalocyaninderivate enthaltender photosensibilisator in der photodynamischen therapie von tumoren ATE216581T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939317881A GB9317881D0 (en) 1993-08-27 1993-08-27 Photosensitizers
PCT/GB1994/001847 WO1995005818A1 (en) 1993-08-27 1994-08-24 Photosensitizers

Publications (1)

Publication Number Publication Date
ATE216581T1 true ATE216581T1 (de) 2002-05-15

Family

ID=10741160

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94924921T ATE216581T1 (de) 1993-08-27 1994-08-24 Phthalocyaninderivate enthaltender photosensibilisator in der photodynamischen therapie von tumoren

Country Status (15)

Country Link
US (2) US5834455A (de)
EP (1) EP0714298B1 (de)
JP (1) JPH09501928A (de)
KR (1) KR100358273B1 (de)
CN (1) CN1099869C (de)
AT (1) ATE216581T1 (de)
AU (1) AU684820B2 (de)
CA (1) CA2170379C (de)
DE (1) DE69430482T2 (de)
DK (1) DK0714298T3 (de)
ES (1) ES2173118T3 (de)
GB (2) GB9317881D0 (de)
NZ (1) NZ271405A (de)
RU (1) RU2159612C2 (de)
WO (1) WO1995005818A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9500116D0 (en) * 1995-01-05 1995-03-01 Ciba Geigy Ag Pharmaceutical compositions
RU2106146C1 (ru) * 1995-07-17 1998-03-10 Институт элементоорганических соединений РАН Средство для подавления опухолевого роста
US5742380A (en) * 1996-12-31 1998-04-21 Ronn Avigdor M Plasma assay spectrometer
IT1294325B1 (it) * 1997-08-14 1999-03-24 Molteni L E C Dei Fratelli Ali Zinco-ftalocianine e relativi coniugati, preparazione e uso nella terapia fotodinamica e come diagnostici
EP1107971B1 (de) 1998-08-28 2004-11-24 Destiny Pharma Limited Porphyrin derivate, ihre verwendung in der photodynamischen therapie und diese enthaltende medizinische geräte
RU2164136C2 (ru) * 1998-09-09 2001-03-20 Государственный научный центр РФ "НИОПИК" Фотосенсибилизатор для фотодинамической терапии
CA2394891A1 (en) * 1999-12-08 2001-06-14 Michael John Cook Substituted phthalocyanines and their precursors
ITFI20050093A1 (it) * 2005-05-05 2006-11-06 Molteni & C Processo per la preparazione di cloruri di derivati ftalocianinici comprendenti almeno un gruppo ammonio quaternario
ITFI20050092A1 (it) * 2005-05-05 2006-11-06 Molteni & C Derivati ftalocianinici, processo per la loro preparazione, composizioni farmaceutiche che li contengono e loro uso
RU2282647C1 (ru) * 2005-05-31 2006-08-27 Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" (ФГУП "ГНЦ "НИОПИК") Фотосенсибилизаторы для антимикробной фотодинамической терапии
RU2282646C1 (ru) * 2005-05-31 2006-08-27 Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" (ФГУП "ГНЦ "НИОПИК") Фотосенсибилизаторы для фотодинамической терапии
JP2009500462A (ja) * 2005-06-29 2009-01-08 エル．モルテニ アンド シー．デイ フラテッリ アリッチ ソシエタ’ディ エセルチヅィオ ソシエタ ペル アチオニ 自己滅菌性製品
EP2072584B1 (de) * 2007-12-17 2011-05-11 ILFORD Imaging Switzerland GmbH Phthalocyanin-Farbstoffe, ihre Herstellung und Verwendung
RU2375371C1 (ru) * 2008-10-07 2009-12-10 Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" (ФГУП "ГНЦ "НИОПИК") Сенсибилизатор и способ фотообеззараживания воды
EP2526103B1 (de) * 2010-01-22 2016-05-04 Council of Scientific & Industrial Research Verfahren zur herstellung neuer porphyrinderivate und deren verwendung als pdt-wirkstoffe und fluoreszenzsonden
RU2459827C2 (ru) * 2010-10-26 2012-08-27 Государственное Научное Учреждение "Институт Физики Имени Б.И. Степанова Национальной Академии Наук Беларуси" Способ получения гибридного фотосенсибилизатора
DE102011007546A1 (de) * 2011-04-15 2012-10-18 Humboldt-Universität Zu Berlin Messvorrichtung für eine Messung einer Singulettsauerstoff-Lumineszenz
RU2470051C1 (ru) * 2011-07-06 2012-12-20 Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" (ФГУП "ГНЦ "НИОПИК") Гетерогенный сенсибилизатор и способ фотообеззараживания воды от вирусного загрязнения
JP2013245139A (ja) * 2012-05-28 2013-12-09 Chiba Inst Of Technology 酸化亜鉛結晶の生成方法
JP6362281B2 (ja) * 2017-03-29 2018-07-25 学校法人千葉工業大学 酸化亜鉛結晶の生成方法
RU2700421C1 (ru) * 2018-07-23 2019-09-17 Федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский Нижегородский государственный университет им. Н.И. Лобачевского" Способ оценки содержания пероксида водорода в опухолевых клетках при фотодинамическом воздействии
EP4174071A4 (de) * 2020-06-24 2024-09-11 The University of Tokyo Photosensibilisierender farbstoff

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988006157A1 (en) * 1987-02-11 1988-08-25 Sandoz-Erfindungen Verwaltungsgesellschaft M.B.H. 5-HETERO- OR ARYL-SUBSTITUTED-IMIDAZO[2,1-a]ISOQUINOLINES
EP0346354B1 (de) * 1987-02-13 1992-08-19 The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Substituierte phthalocyanine
EP0434727A4 (en) * 1988-09-08 1994-08-17 Ultra Diagnostic Corp Red-shifted phthalocyanine and tetrabenztriazaporphyrin reagents
US5120649A (en) * 1990-05-15 1992-06-09 New York Blood Center, Inc. Photodynamic inactivation of viruses in blood cell-containing compositions
US5166197A (en) * 1990-07-17 1992-11-24 Kenney Malcolm E Phthalocyanine photosensitizers for photodynamic therapy
ES2094795T3 (es) * 1990-11-02 1997-02-01 Ici Plc Ftalocianinas polisustituidas.
GB9122798D0 (en) * 1991-10-28 1991-12-11 Ici Plc Substituted phthalocyanines
GB9123814D0 (en) * 1991-11-08 1992-01-02 Johnson Matthey Plc Photosensitizers

Also Published As

Publication number Publication date
AU684820B2 (en) 1998-01-08
CN1133559A (zh) 1996-10-16
US6096734A (en) 2000-08-01
DE69430482D1 (de) 2002-05-29
NZ271405A (en) 1998-04-27
CA2170379A1 (en) 1995-03-02
GB2295547A (en) 1996-06-05
AU7502594A (en) 1995-03-21
ES2173118T3 (es) 2002-10-16
GB9602255D0 (en) 1996-04-10
CA2170379C (en) 2008-04-15
WO1995005818A1 (en) 1995-03-02
EP0714298A1 (de) 1996-06-05
RU2159612C2 (ru) 2000-11-27
DE69430482T2 (de) 2002-11-21
KR960703586A (ko) 1996-08-31
CN1099869C (zh) 2003-01-29
GB2295547B (en) 1997-12-17
KR100358273B1 (ko) 2003-05-12
DK0714298T3 (da) 2002-08-19
GB9317881D0 (en) 1993-10-13
EP0714298B1 (de) 2002-04-24
JPH09501928A (ja) 1997-02-25
US5834455A (en) 1998-11-10

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Legal Events

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REN Ceased due to non-payment of the annual fee