ATE216712T1 - Zweistufige lösungspolymerisation von hochmolekularen poly(phosphorestern) - Google Patents
Zweistufige lösungspolymerisation von hochmolekularen poly(phosphorestern)Info
- Publication number
- ATE216712T1 ATE216712T1 AT98930301T AT98930301T ATE216712T1 AT E216712 T1 ATE216712 T1 AT E216712T1 AT 98930301 T AT98930301 T AT 98930301T AT 98930301 T AT98930301 T AT 98930301T AT E216712 T1 ATE216712 T1 AT E216712T1
- Authority
- AT
- Austria
- Prior art keywords
- formula
- polymer
- solvent
- compound
- phosphoresters
- Prior art date
Links
- 238000010528 free radical solution polymerization reaction Methods 0.000 title 1
- 229920000642 polymer Polymers 0.000 abstract 4
- 239000002904 solvent Substances 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000000379 polymerizing effect Effects 0.000 abstract 2
- 239000011541 reaction mixture Substances 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G79/00—Macromolecular compounds obtained by reactions forming a linkage containing atoms other than silicon, sulfur, nitrogen, oxygen, and carbon with or without the latter elements in the main chain of the macromolecule
- C08G79/02—Macromolecular compounds obtained by reactions forming a linkage containing atoms other than silicon, sulfur, nitrogen, oxygen, and carbon with or without the latter elements in the main chain of the macromolecule a linkage containing phosphorus
- C08G79/04—Phosphorus linked to oxygen or to oxygen and carbon
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Polyesters Or Polycarbonates (AREA)
- Manufacture Of Macromolecular Shaped Articles (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87762497A | 1997-06-18 | 1997-06-18 | |
| US09/098,620 US6008318A (en) | 1997-06-18 | 1998-06-17 | Two-stage solution polymerization of high molecular weight poly(phosphoesters) |
| PCT/US1998/012553 WO1998058012A1 (en) | 1997-06-18 | 1998-06-17 | Two-stage solution polymerization of high molecular weight poly(phosphoesters) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE216712T1 true ATE216712T1 (de) | 2002-05-15 |
Family
ID=25370360
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98930301T ATE216712T1 (de) | 1997-06-18 | 1998-06-17 | Zweistufige lösungspolymerisation von hochmolekularen poly(phosphorestern) |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6008318A (de) |
| EP (1) | EP0991699B1 (de) |
| JP (1) | JP2002515939A (de) |
| AT (1) | ATE216712T1 (de) |
| AU (1) | AU746351B2 (de) |
| CA (1) | CA2295209A1 (de) |
| DE (1) | DE69805071T2 (de) |
| WO (1) | WO1998058012A1 (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9809064A (pt) | 1997-04-03 | 2002-01-02 | Guilford Pharm Inc | Polìmeros biodegradáveis de poliéster de tereftalato-polifosfato, composições, artigos e métodos para fazer e usar os mesmos |
| UA54505C2 (uk) | 1997-04-03 | 2003-03-17 | Гілфорд Фармасьютікалз Інк. | Полімери, що біологічно розкладаються, зшиті фосфатами, композиції, вироби і способи для їх виготовлення і використання |
| US6548302B1 (en) | 1998-06-18 | 2003-04-15 | Johns Hopkins University School Of Medicine | Polymers for delivery of nucleic acids |
| US6153212A (en) * | 1998-10-02 | 2000-11-28 | Guilford Pharmaceuticals Inc. | Biodegradable terephthalate polyester-poly (phosphonate) compositions, articles, and methods of using the same |
| US6419709B1 (en) | 1998-10-02 | 2002-07-16 | Guilford Pharmaceuticals, Inc. | Biodegradable terephthalate polyester-poly(Phosphite) compositions, articles, and methods of using the same |
| US6350464B1 (en) | 1999-01-11 | 2002-02-26 | Guilford Pharmaceuticals, Inc. | Methods for treating ovarian cancer, poly (phosphoester) compositions, and biodegradable articles for same |
| US6537585B1 (en) | 1999-03-26 | 2003-03-25 | Guilford Pharmaceuticals, Inc. | Methods and compositions for treating solid tumors |
| AU2001269961A1 (en) | 2000-07-06 | 2002-01-21 | Guilford Pharmaceuticals | Improved polymers and polymerization processes |
| SG125885A1 (en) * | 2000-12-05 | 2006-10-30 | Univ Singapore | A polymer and nerve guide conduits formed thereof |
| US6555581B1 (en) | 2001-02-15 | 2003-04-29 | Jones Pharma, Inc. | Levothyroxine compositions and methods |
| US7067148B2 (en) | 2001-02-15 | 2006-06-27 | King Pharmaceutical Research & Development, Inc. | Stabilized pharmaceutical and thyroid hormone compositions and method of preparation |
| AU2002354957A1 (en) * | 2001-07-19 | 2003-03-03 | Guilford Pharmaceuticals, Inc. | Biocompatible polymer containing composition for treatment of prostate cancers |
| US20030134892A1 (en) * | 2001-07-19 | 2003-07-17 | Wenbin Dang | Compositions for treatment of head and neck cancers, and methods of making and using the same |
| US7101569B2 (en) | 2001-08-14 | 2006-09-05 | Franz G Andrew | Methods of administering levothyroxine pharmaceutical compositions |
| US20030180356A1 (en) * | 2001-10-29 | 2003-09-25 | Franz G. Andrew | Levothyroxine compositions having unique triiodothyronine Tmax properties |
| WO2003080629A2 (en) | 2002-02-25 | 2003-10-02 | Guilford Pharmaceuticals, Inc. | Phosphorus-containing compounds with polymeric chains, and methods of making and using the same |
| US20040197301A1 (en) * | 2003-02-18 | 2004-10-07 | Zhong Zhao | Hybrid polymers and methods of making the same |
| RU2396289C2 (ru) * | 2004-08-13 | 2010-08-10 | Рева Медикал, Инк. | Саморассасывающиеся рентгеноконтрастные по своей природе полимеры для многоцелевого использования |
| US20110223664A1 (en) * | 2006-11-16 | 2011-09-15 | The University Of Akron | Materials and methods of introducing genetic material into living cells |
| JP6205133B2 (ja) | 2009-07-10 | 2017-09-27 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー |
| CN105984147B (zh) | 2015-02-04 | 2018-11-30 | 三纬国际立体列印科技股份有限公司 | 立体打印装置 |
| KR20180069782A (ko) | 2015-08-03 | 2018-06-25 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 하전 이온 채널 블록커 및 이용 방법 |
| US10828287B2 (en) | 2019-03-11 | 2020-11-10 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| AU2020235888A1 (en) | 2019-03-11 | 2021-09-30 | Nocion Therapeutics, Inc. | Charged ION channel blockers and methods for use |
| US10780083B1 (en) | 2019-03-11 | 2020-09-22 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| MX2021010869A (es) | 2019-03-11 | 2022-01-19 | Nocion Therapeutics Inc | Bloqueadores de canales iónicos sustituidos por éster y métodos para su uso. |
| US10934263B2 (en) | 2019-03-11 | 2021-03-02 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| US10933055B1 (en) | 2019-11-06 | 2021-03-02 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| CN114828845A (zh) | 2019-11-06 | 2022-07-29 | 诺西恩医疗公司 | 带电的离子通道阻滞剂及其使用方法 |
| US12162851B2 (en) | 2020-03-11 | 2024-12-10 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| CN119118953A (zh) | 2020-03-11 | 2024-12-13 | 诺西恩医疗公司 | 带电的离子通道阻滞剂及其使用方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5750812B2 (de) * | 1973-06-25 | 1982-10-29 | ||
| US5265265A (en) * | 1990-02-09 | 1993-11-23 | Seiko Epson Corporation | Wristwatch radio communication device having an improved noise shielding structure |
| US5194581A (en) * | 1989-03-09 | 1993-03-16 | Leong Kam W | Biodegradable poly(phosphoesters) |
| US5256265A (en) * | 1991-03-18 | 1993-10-26 | Cha Chang Y | Process for oxide reactions by radiofrequency-char catalysis |
-
1998
- 1998-06-17 US US09/098,620 patent/US6008318A/en not_active Expired - Lifetime
- 1998-06-17 JP JP50470699A patent/JP2002515939A/ja active Pending
- 1998-06-17 AT AT98930301T patent/ATE216712T1/de not_active IP Right Cessation
- 1998-06-17 DE DE69805071T patent/DE69805071T2/de not_active Expired - Fee Related
- 1998-06-17 CA CA002295209A patent/CA2295209A1/en not_active Withdrawn
- 1998-06-17 EP EP98930301A patent/EP0991699B1/de not_active Expired - Lifetime
- 1998-06-17 AU AU79721/98A patent/AU746351B2/en not_active Ceased
- 1998-06-17 WO PCT/US1998/012553 patent/WO1998058012A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU746351B2 (en) | 2002-04-18 |
| AU7972198A (en) | 1999-01-04 |
| JP2002515939A (ja) | 2002-05-28 |
| DE69805071T2 (de) | 2002-11-14 |
| CA2295209A1 (en) | 1998-12-23 |
| WO1998058012A1 (en) | 1998-12-23 |
| EP0991699B1 (de) | 2002-04-24 |
| EP0991699A1 (de) | 2000-04-12 |
| US6008318A (en) | 1999-12-28 |
| DE69805071D1 (de) | 2002-05-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |