ATE216780T1 - Bestimmung von steroiden durch kompetitiven immunoassay - Google Patents
Bestimmung von steroiden durch kompetitiven immunoassayInfo
- Publication number
- ATE216780T1 ATE216780T1 AT96908511T AT96908511T ATE216780T1 AT E216780 T1 ATE216780 T1 AT E216780T1 AT 96908511 T AT96908511 T AT 96908511T AT 96908511 T AT96908511 T AT 96908511T AT E216780 T1 ATE216780 T1 AT E216780T1
- Authority
- AT
- Austria
- Prior art keywords
- steroid
- solid phase
- kit
- conjugate
- mixture
- Prior art date
Links
- 150000003431 steroids Chemical class 0.000 title abstract 11
- 238000002967 competitive immunoassay Methods 0.000 title abstract 2
- 239000007790 solid phase Substances 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 3
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 abstract 2
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 230000002860 competitive effect Effects 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 229960005309 estradiol Drugs 0.000 abstract 1
- 229930182833 estradiol Natural products 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
- 229960003387 progesterone Drugs 0.000 abstract 1
- 239000000186 progesterone Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/743—Steroid hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0016—Oximes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/806—Fertility tests
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/906—Fertility tests
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Endocrinology (AREA)
- Steroid Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/398,226 US5663054A (en) | 1995-03-03 | 1995-03-03 | Determination of steroids by competitive immunoassay |
| PCT/US1996/002495 WO1996027800A1 (en) | 1995-03-03 | 1996-02-26 | Determination of steroids by competitive immunoassay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE216780T1 true ATE216780T1 (de) | 2002-05-15 |
Family
ID=23574524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96908511T ATE216780T1 (de) | 1995-03-03 | 1996-02-26 | Bestimmung von steroiden durch kompetitiven immunoassay |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US5663054A (de) |
| EP (1) | EP0813684B1 (de) |
| JP (1) | JP3640970B2 (de) |
| AT (1) | ATE216780T1 (de) |
| CA (1) | CA2214085A1 (de) |
| DE (1) | DE69620876T2 (de) |
| ES (1) | ES2176445T3 (de) |
| WO (1) | WO1996027800A1 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5854009A (en) * | 1995-09-19 | 1998-12-29 | Immuna Care Corporation | Method of detecting estrogen-sensitive pathologies |
| US5977319A (en) * | 1996-10-21 | 1999-11-02 | Cambridge Antibody Technology Limited | Specific binding members for estradiol; materials and methods |
| US6300082B1 (en) * | 1998-03-20 | 2001-10-09 | Ia, Inc. | Method and apparatus for measurement of the effect of test compounds on signal transduction at the level of biological receptors |
| CA2283597C (en) | 1998-10-02 | 2008-02-05 | Ortho-Clinical Diagnostics, Inc. | Reduced cortisol conjugates |
| AU5916499A (en) * | 1999-09-10 | 2001-04-17 | Biex, Inc. | Hormone replacement therapy monitoring |
| US6174665B1 (en) | 1999-09-10 | 2001-01-16 | Biex, Inc. | Hormone replacement therapy monitoring |
| US7410807B2 (en) * | 2000-07-24 | 2008-08-12 | D Aurora Vito J | Pregnancy and sex identification test based on saliva or other bodily fluids |
| US20030124618A1 (en) * | 2001-12-04 | 2003-07-03 | Lattec I/S | Device for analysing analyte compounds and use hereof |
| JP3637392B2 (ja) * | 2002-04-08 | 2005-04-13 | 独立行政法人産業技術総合研究所 | 燃料電池 |
| US20040138187A1 (en) | 2002-08-28 | 2004-07-15 | Reading Christopher L. | Therapeutic treatment methods |
| US20060068501A1 (en) * | 2004-09-30 | 2006-03-30 | Nj International Llc | Apparatus and methods for steroid hormone testing |
| CA2637705C (en) * | 2006-01-19 | 2013-10-29 | Lattec I/S | A novel dry stick device construction and method for determining an analyte in a sample using said dry stick device |
| PL1982183T3 (pl) * | 2006-01-19 | 2012-11-30 | Lattec I/S | Urządzenie suchego paska i sposób oznaczania analitu w próbce |
| WO2008106149A1 (en) * | 2007-02-28 | 2008-09-04 | Children's Medical Center Corporation | Methods for predicting the onset of menarche |
| JP5701666B2 (ja) * | 2011-04-14 | 2015-04-15 | 株式会社Ｌｓｉメディエンス | 高親和性抗ハプテンポリクローナル抗体の作製法 |
| EP2742352B1 (de) * | 2011-08-12 | 2018-02-28 | Siemens Healthcare Diagnostics Inc. | Nachweis von sexualhormonen |
| JP6221466B2 (ja) * | 2013-07-29 | 2017-11-01 | 東ソー株式会社 | ハプテンの測定方法 |
| GB201317458D0 (en) * | 2013-10-02 | 2013-11-13 | Spd Swiss Prec Diagnostics Gmbh | Improved pregnancy test device and method |
| CN106574929B (zh) | 2014-07-25 | 2019-08-09 | 贝克顿·迪金森公司 | 分析物测试条试验以及用于其实施的测试条和试剂盒 |
| CN108139410A (zh) | 2015-04-02 | 2018-06-08 | 瑞士斯保德精密诊断有限公司 | 改进的怀孕测试装置及方法 |
| EP3634418A1 (de) | 2017-06-05 | 2020-04-15 | ObsEva S.A. | Dosierschemata für gonadotropin-freisetzenden hormonantagonisten zur behandlung von endometriose |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4282325A (en) * | 1971-05-14 | 1981-08-04 | Syva Company | Enzyme bound corticosteroids |
| US4275149A (en) * | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| JPS60260592A (ja) * | 1984-06-08 | 1985-12-23 | Teikoku Hormone Mfg Co Ltd | ステロイド測定用抗原 |
| EP0200960A1 (de) * | 1985-05-08 | 1986-11-12 | Abbott Laboratories | Fluoreszenzpolarisationsimmunoassay auf Gesamtöstriol |
| US4857652A (en) * | 1986-07-17 | 1989-08-15 | Board Of Governors Of Wayne State University | Chemiluminescent 1,2-dioxetane compounds |
| US4962192A (en) * | 1986-07-17 | 1990-10-09 | Board Of Governors Of Wayne State University | Chemiluminescent 1,2-dioxetane compounds |
| WO1988000695A1 (en) * | 1986-07-24 | 1988-01-28 | Quest Systems, Inc. | Method of detecting a substance using enzymatically-induced decomposition of dioxetanes |
| DE58901057D1 (de) * | 1988-01-25 | 1992-05-07 | Boehringer Mannheim Gmbh | Neue haptenderivate und davon abgeleitete hapten-protein-konjugate. |
| FR2627588A1 (fr) * | 1988-02-24 | 1989-08-25 | Ire Medgenix Sa | Procede de dosage immunologique d'une substance de structure haptenique |
| JPH02213766A (ja) * | 1989-02-15 | 1990-08-24 | Mochida Pharmaceut Co Ltd | 免疫測定用試薬および免疫測定器具 |
| GB8926407D0 (en) * | 1989-11-22 | 1990-01-10 | Gen Electric Plc | Polymers |
| US5342760A (en) * | 1992-06-10 | 1994-08-30 | Abbott Laboratories | Determination of estradiol by competitive immunoassay |
| US5395938A (en) * | 1992-08-21 | 1995-03-07 | Nichols Institute Diagnostics | Biotinylated chemiluminescent labels and their conjugates, assays and assay kits |
| US5491071A (en) * | 1993-08-03 | 1996-02-13 | Abbott Laboratories | Reagents and methods for the detection and quantification of testosterone in fluid samples |
-
1995
- 1995-03-03 US US08/398,226 patent/US5663054A/en not_active Expired - Fee Related
-
1996
- 1996-02-26 DE DE69620876T patent/DE69620876T2/de not_active Expired - Fee Related
- 1996-02-26 WO PCT/US1996/002495 patent/WO1996027800A1/en not_active Ceased
- 1996-02-26 CA CA002214085A patent/CA2214085A1/en not_active Abandoned
- 1996-02-26 JP JP52689896A patent/JP3640970B2/ja not_active Expired - Fee Related
- 1996-02-26 AT AT96908511T patent/ATE216780T1/de not_active IP Right Cessation
- 1996-02-26 ES ES96908511T patent/ES2176445T3/es not_active Expired - Lifetime
- 1996-02-26 EP EP96908511A patent/EP0813684B1/de not_active Expired - Lifetime
-
1997
- 1997-04-16 US US08/840,782 patent/US5932431A/en not_active Expired - Lifetime
-
1999
- 1999-06-18 US US09/336,884 patent/US6201141B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US5663054A (en) | 1997-09-02 |
| EP0813684B1 (de) | 2002-04-24 |
| EP0813684A1 (de) | 1997-12-29 |
| DE69620876T2 (de) | 2002-12-12 |
| ES2176445T3 (es) | 2002-12-01 |
| JPH11501397A (ja) | 1999-02-02 |
| CA2214085A1 (en) | 1996-09-12 |
| DE69620876D1 (de) | 2002-05-29 |
| US5932431A (en) | 1999-08-03 |
| WO1996027800A1 (en) | 1996-09-12 |
| JP3640970B2 (ja) | 2005-04-20 |
| US6201141B1 (en) | 2001-03-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |