ATE216990T1 - Verfahren zur herstellung von 1-substituierten 4- cyan-1,2,3-triazolen - Google Patents

Verfahren zur herstellung von 1-substituierten 4- cyan-1,2,3-triazolen

Info

Publication number: ATE216990T1
Authority: AT; Austria
Prior art keywords: aliphatic; triazoles; cyan; substituted; producing
Prior art date: 1996-07-11

Application number

AT97932803T

Other languages

English (en)

Inventor

Robert Portmann

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-07-11

Filing date

1997-07-10

Publication date

2002-05-15

1997-07-10 Application filed by Novartis Ag filed Critical Novartis Ag

2002-05-15 Application granted granted Critical

2002-05-15 Publication of ATE216990T1 publication Critical patent/ATE216990T1/de

Links

238000004519 manufacturing process Methods 0.000 title 1
PVIAOIJYIQHKPL-UHFFFAOYSA-N 1-[(2,6-difluorophenyl)methyl]triazole-4-carbonitrile Chemical compound FC1=CC=CC(F)=C1CN1N=NC(C#N)=C1 PVIAOIJYIQHKPL-UHFFFAOYSA-N 0.000 abstract 1
OYUNTGBISCIYPW-UHFFFAOYSA-N 2-chloroprop-2-enenitrile Chemical compound ClC(=C)C#N OYUNTGBISCIYPW-UHFFFAOYSA-N 0.000 abstract 1
UVQSQWZYJWNHSU-UHFFFAOYSA-N 2h-triazole-4-carbonitrile Chemical class N#CC1=CNN=N1 UVQSQWZYJWNHSU-UHFFFAOYSA-N 0.000 abstract 1
125000001931 aliphatic group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
150000001540 azides Chemical class 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Physical Education & Sports Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Orthopedic Medicine & Surgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Pharmacology & Pharmacy (AREA)
Neurology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Silver Salt Photography Or Processing Solution Therefor (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT97932803T 1996-07-11 1997-07-10 Verfahren zur herstellung von 1-substituierten 4- cyan-1,2,3-triazolen ATE216990T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CH174796		1996-07-11
PCT/EP1997/003671 WO1998002423A1 (en)	1996-07-11	1997-07-10	Process for preparing 1-substituted 4-cyano-1,2,3-triazoles

Publications (1)

Publication Number	Publication Date
ATE216990T1 true ATE216990T1 (de)	2002-05-15

Family

ID=4217633

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97932803T ATE216990T1 (de)	1996-07-11	1997-07-10	Verfahren zur herstellung von 1-substituierten 4- cyan-1,2,3-triazolen

Country Status (24)

Country	Link
US (2)	US6156907A (de)
EP (1)	EP0918758B1 (de)
JP (1)	JP3537147B2 (de)
KR (1)	KR100481137B1 (de)
CN (1)	CN1083436C (de)
AT (1)	ATE216990T1 (de)
AU (1)	AU719148B2 (de)
BR (1)	BR9710252B1 (de)
CA (1)	CA2260065C (de)
CZ (1)	CZ294775B6 (de)
DE (1)	DE69712342T2 (de)
DK (1)	DK0918758T3 (de)
ES (1)	ES2176758T3 (de)
HU (1)	HU226425B1 (de)
IL (1)	IL127665A (de)
NO (1)	NO326347B1 (de)
NZ (1)	NZ333505A (de)
PL (1)	PL189232B1 (de)
PT (1)	PT918758E (de)
RU (1)	RU2177942C2 (de)
SI (1)	SI0918758T1 (de)
SK (1)	SK283990B6 (de)
TR (1)	TR199900017T2 (de)
WO (1)	WO1998002423A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW526195B (en) *	1997-06-10	2003-04-01	Novartis Ag	Crystal modifications of 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide and their use
CN100335467C (zh) *	2004-06-04	2007-09-05	中国科学院上海有机化学研究所	一锅法区域选择性合成5－碘代－1，4－二取代－1，2，3－三氮唑化合物
US8183269B2 (en)	2008-10-13	2012-05-22	Cipla Limited	Process for the preparation of rufinamide
EP2378879A4 (de) *	2008-12-16	2012-06-06	Merck Sharp & Dohme	Triazolderivate für die behandlung von morbus alzheimer
CN101768124B (zh) *	2008-12-30	2012-01-04	北京本草天源药物研究院	一种药物晶体及其制备方法和用途
EP2640711B1 (de) *	2010-08-25	2015-10-14	Davuluri, Ramamohan Rao	Verbessertes verfahren zur herstellung von rufinamid
WO2012032540A1 (en)	2010-09-06	2012-03-15	Indoco Remedies Limited	Process for preparation of fluorinated triazole compound
CN102219752B (zh) *	2011-04-21	2013-04-10	华润赛科药业有限责任公司	一种1-(2,6-二氟苄基)-1h-1,2,3-三唑-4-甲酰胺的晶型d
WO2014072992A1 (en)	2012-11-12	2014-05-15	Aarti Industries Limited	A process for preparing triazole compounds
RU2591206C1 (ru) *	2015-04-14	2016-07-20	Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Российский химико-технологический университет имени Д.И. Менделеева (РХТУ им. Д.И. Менделеева)"	Замещенные 1-(1-трет-бутил-1н-имидазол-4-ил)-1н-1,2,3-триазолы, способ их получения и фунгицидная композиция на их основе
CN117050027B (zh) *	2023-08-14	2026-03-06	宿州亿帆药业有限公司	一种卢非酰胺杂质对照品的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS596305B2 (ja) *	1980-03-11	1984-02-10	工業技術院長	１，２，３−トリアゾ−ル誘導体の製造方法
US4397753A (en) *	1982-09-20	1983-08-09	Circuit Chemistry Corporation	Solder stripping solution
US4789680A (en) *	1982-12-23	1988-12-06	Ciba-Geigy Corporation	Aralkyltriazole compounds
FI93544C (fi) *	1985-04-18	1995-04-25	Ciba Geigy Ag	Menetelmä fluorattujen, antikonvulsiivisesti vaikuttavien 1-bentsyyli-1H-1,2,3-triatsoliyhdisteiden valmistamiseksi

1997
- 1997-07-10 AT AT97932803T patent/ATE216990T1/de active
- 1997-07-10 WO PCT/EP1997/003671 patent/WO1998002423A1/en not_active Ceased
- 1997-07-10 AU AU36220/97A patent/AU719148B2/en not_active Expired
- 1997-07-10 DK DK97932803T patent/DK0918758T3/da active
- 1997-07-10 KR KR10-1999-7000041A patent/KR100481137B1/ko not_active Expired - Lifetime
- 1997-07-10 HU HU9902842A patent/HU226425B1/hu unknown
- 1997-07-10 NZ NZ333505A patent/NZ333505A/en not_active IP Right Cessation
- 1997-07-10 CN CN97196266A patent/CN1083436C/zh not_active Expired - Lifetime
- 1997-07-10 SK SK26-99A patent/SK283990B6/sk not_active IP Right Cessation
- 1997-07-10 PL PL97330914A patent/PL189232B1/pl unknown
- 1997-07-10 BR BRPI9710252-0A patent/BR9710252B1/pt not_active IP Right Cessation
- 1997-07-10 PT PT97932803T patent/PT918758E/pt unknown
- 1997-07-10 TR TR1999/00017T patent/TR199900017T2/xx unknown
- 1997-07-10 RU RU99102673/04A patent/RU2177942C2/ru active
- 1997-07-10 ES ES97932803T patent/ES2176758T3/es not_active Expired - Lifetime
- 1997-07-10 US US09/214,698 patent/US6156907A/en not_active Expired - Lifetime
- 1997-07-10 CA CA002260065A patent/CA2260065C/en not_active Expired - Lifetime
- 1997-07-10 JP JP50559598A patent/JP3537147B2/ja not_active Expired - Lifetime
- 1997-07-10 CZ CZ199942A patent/CZ294775B6/cs not_active IP Right Cessation
- 1997-07-10 IL IL12766597A patent/IL127665A/en not_active IP Right Cessation
- 1997-07-10 EP EP97932803A patent/EP0918758B1/de not_active Expired - Lifetime
- 1997-07-10 SI SI9730358T patent/SI0918758T1/xx unknown
- 1997-07-10 DE DE69712342T patent/DE69712342T2/de not_active Expired - Lifetime
1999
- 1999-01-07 NO NO19990056A patent/NO326347B1/no not_active IP Right Cessation
2000
- 2000-10-18 US US09/691,484 patent/US6277999B1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0918758B1 (de)	2002-05-02
US6156907A (en)	2000-12-05
CN1083436C (zh)	2002-04-24
EP0918758A1 (de)	1999-06-02
SI0918758T1 (en)	2002-10-31
BR9710252A (pt)	1999-08-10
KR20000023595A (ko)	2000-04-25
SK283990B6 (sk)	2004-07-07
US6277999B1 (en)	2001-08-21
JP2000507602A (ja)	2000-06-20
KR100481137B1 (ko)	2005-04-08
BR9710252B1 (pt)	2010-06-29
WO1998002423A1 (en)	1998-01-22
DE69712342D1 (de)	2002-06-06
CZ4299A3 (cs)	1999-04-14
CN1225087A (zh)	1999-08-04
AU719148B2 (en)	2000-05-04
DE69712342T2 (de)	2002-11-14
ES2176758T3 (es)	2002-12-01
CZ294775B6 (cs)	2005-03-16
HUP9902842A2 (hu)	2000-02-28
NO990056D0 (no)	1999-01-07
AU3622097A (en)	1998-02-09
PL189232B1 (pl)	2005-07-29
NZ333505A (en)	2000-06-23
RU2177942C2 (ru)	2002-01-10
PL330914A1 (en)	1999-06-07
CA2260065A1 (en)	1998-01-22
NO990056L (no)	1999-01-07
IL127665A (en)	2004-03-28
IL127665A0 (en)	1999-10-28
JP3537147B2 (ja)	2004-06-14
DK0918758T3 (da)	2002-08-19
HUP9902842A3 (en)	2000-04-28
TR199900017T2 (xx)	1999-04-21
NO326347B1 (no)	2008-11-17
PT918758E (pt)	2002-09-30
SK2699A3 (en)	1999-06-11
HU226425B1 (en)	2008-12-29
CA2260065C (en)	2006-10-17

Legal Events

Date	Code	Title	Description
2002-09-15	UEP	Publication of translation of european patent specification

Publication	Publication Date	Title
DE69712342D1 (de)	2002-06-06	Verfahren zur herstellung von 1-substituierten 4-cyan-1,2,3-triazolen
AU2777089A (en)	1989-07-13	Substituted pyrrole, pyrazole and triazole angiotensin 11 antagonists
CA2315266A1 (en)	1999-06-24	Wound healing compositions
AU1380897A (en)	1997-07-28	Method for synthesizing aryl hydrazine through reduction of diazo compound derivative
DE69324329D1 (de)	1999-05-12	Gesinterter Verbundwerkstoff auf Aluminiumoxidbasis von hoher Zähigkeit sowie Verfahren zu seiner Herstellung
ATE226198T1 (de)	2002-11-15	Ein verfahren zur herstellung von tetraaza makrocyclen
DE59907053D1 (de)	2003-10-23	Verfahren zur herstellung von 1-substituierten 5- oder 3-hydroxy-pyrazolen
ATE187959T1 (de)	2000-01-15	Lösungsmittelfreies verfahren zur herstellung von 2,6 difluorbenzonitril
DE69503364D1 (de)	1998-08-13	Verfahren zur herstellung von polymorphe b und c von 1-(2,4-dichloro-beta-((7-chloro-benzo(b)thien-3-yl)methoxy)phenethyl) imidazol-mononitrat
DE69707825D1 (de)	2001-12-06	Verfahren zur Herstellung von alicyclischen Hydrazin-derivaten.
DE69016587D1 (de)	1995-03-16	Verfahren zur Herstellung von 5-Amino-3-chlorsulfonyl-1,2,4-triazol.
DE69405922D1 (de)	1997-11-06	Verfahren zur Herstellung von 4-substituierten Azetidinon-Derivaten
FI870036L (fi)	1987-07-07	Foerfarande foer framstaellning av trisubstituerade triazoler.
DE69934544D1 (de)	2007-02-08	Verfahren zur Herstellung von 1,2,4-Triazolen ausgehend von Ketazinen
DE69911640D1 (de)	2003-10-30	Verfahren zur herstellung von symmetrischen diacylhydrazinen
ATE168112T1 (de)	1998-07-15	Verfahren zur herstellung von polymorphe b und c von 1-(2,4-dichloro-beta-((7-chloro-benzo(b)thien-3 yl)methoxy)phenethyl) imidazol-mononitrat
ATE300530T1 (de)	2005-08-15	Azol- oder triazol-derivate, verfahren zu deren herstellung und ihre verwendung als antifungale arzneimittel
DE59906901D1 (de)	2003-10-09	Verfahren zur herstellung von 1-substituierten 5-hydroxypyrazolen
DE3882661D1 (de)	1993-09-02	Verfahren zur herstellung von 3-mercapto-5-amino-(1h)-1,2,4-triazol.
DE60313124D1 (de)	2007-05-24	Verfahren zur herstellung einer 1,2,3-triazolverbindung
DE69400715D1 (de)	1996-11-21	Verfahren zur Herstellung 4-halo-5(hydroxymethyl)-imidazol Derivate und neue 4-chloro-imidazol Verbindungen
PL349999A1 (en)	2002-10-21	In vivo
DE69018888D1 (de)	1995-06-01	Verfahren zur Herstellung von Imidazolidin-2,5-dion-Derivaten.
ATE161529T1 (de)	1998-01-15	Verfahren zur herstellung von 6-aryloxymethyl-1- hydroxy-4-methyl-2-pyridonen
WO1996002532A1 (de)	1996-02-01	7-substituierte 1-[4-(1h-1,2,4-triazol-1-yl-methyl)phenyl] substituierte chinoloncarbonsäuren als antivirale mittel