ATE217013T1 - Upa-bindungstelle auf 2+3 domäne von upar und damit reagierende antikörper - Google Patents

Upa-bindungstelle auf 2+3 domäne von upar und damit reagierende antikörper

Info

Publication number
ATE217013T1
ATE217013T1 AT95610039T AT95610039T ATE217013T1 AT E217013 T1 ATE217013 T1 AT E217013T1 AT 95610039 T AT95610039 T AT 95610039T AT 95610039 T AT95610039 T AT 95610039T AT E217013 T1 ATE217013 T1 AT E217013T1
Authority
AT
Austria
Prior art keywords
par
antibody
dsm
relates
upar
Prior art date
Application number
AT95610039T
Other languages
English (en)
Inventor
Ulrich Pessara
Ulrich Weidle
Bernhard Koenig
Ulrich Kohnert
Ilse Bartke
Keld Dano
Michael Ploug
Vincent Ellis
Original Assignee
Cancerforskningsfonden Af 1989
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancerforskningsfonden Af 1989, Roche Diagnostics Gmbh filed Critical Cancerforskningsfonden Af 1989
Application granted granted Critical
Publication of ATE217013T1 publication Critical patent/ATE217013T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT95610039T 1994-07-08 1995-06-22 Upa-bindungstelle auf 2+3 domäne von upar und damit reagierende antikörper ATE217013T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK83194 1994-07-08

Publications (1)

Publication Number Publication Date
ATE217013T1 true ATE217013T1 (de) 2002-05-15

Family

ID=8098050

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95610039T ATE217013T1 (de) 1994-07-08 1995-06-22 Upa-bindungstelle auf 2+3 domäne von upar und damit reagierende antikörper

Country Status (7)

Country Link
US (1) US6025142A (de)
EP (1) EP0691350B1 (de)
JP (1) JP2852192B2 (de)
AT (1) ATE217013T1 (de)
CA (1) CA2153208A1 (de)
DE (1) DE69526542T2 (de)
ES (1) ES2176302T3 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6077508A (en) * 1998-03-23 2000-06-20 American Diagnostica Inc. Urokinase plasminogen activator receptor as a target for diagnosis of metastases
WO2002009753A1 (en) * 2000-08-02 2002-02-07 H:S Hvidovre Hospital Composition and method for the treatment or prevention of hiv infection
ATE361096T1 (de) 2001-01-25 2007-05-15 San Raffaele Centro Fond Antikörper zur modulierung der upa/upar interaktion und deren verwendungen
EP1393743A1 (de) * 2001-01-25 2004-03-03 Fondazione Centro San Raffaele Del Monte Tabor Substanzen zur Modulierung der uPA/uPAR Aktivität zur Behandlung von AIDS
AU2003274059A1 (en) * 2002-10-23 2004-05-13 F. Hoffmann-La Roche Ag Combination of a trioxopyrimidine compound inhibitor and an anti-tumor agent, and uses thereof
DE10323898A1 (de) 2003-05-26 2004-12-23 Wilex Ag Hydroxyamidin- und Hydroxyguanidin-Verbindungen als Urokinase-Hemmstoffe
TW200813091A (en) * 2006-04-10 2008-03-16 Amgen Fremont Inc Targeted binding agents directed to uPAR and uses thereof
DK2117571T3 (en) * 2006-12-08 2017-05-08 Monopar Therapeutics Inc Urokinase-type plasminogen activator receptor epitope
US20130017624A1 (en) 2010-03-30 2013-01-17 Ge Healthcare Bio-Sciences Ab Method for determination of binding stoichiometry

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5327493A (en) 1976-08-27 1978-03-14 Risei Ui Ultra micro analysis for acetone and kit for carrying out the analysis
US5519120A (en) * 1989-04-07 1996-05-21 Cancerforskningsfondet Af 1989 Urokinase-type plasminogen activator receptor antibodies
AU652917B2 (en) * 1989-04-07 1994-09-15 Cancerforskningsfondet Af 1989 Urokinase-type plasminogen activator receptor
JPH07500486A (ja) * 1990-10-18 1995-01-19 カンサーフォースクニングスフォンデン・アフ・１９８９（フォンデン・チル・フレメ・アフ・エクスペリメンテル・カンサーフォースクニング） ウロキナーゼレセプターに対する抗体とその用途
CA2123874A1 (en) * 1991-11-18 1993-05-27 Ikuko F. Mizukami Methods for detecting and isolating upa-r and inhibiting the binding of upa to upa-r

Also Published As

Publication number Publication date
JPH0859700A (ja) 1996-03-05
JP2852192B2 (ja) 1999-01-27
US6025142A (en) 2000-02-15
EP0691350A2 (de) 1996-01-10
EP0691350A3 (de) 1996-11-27
EP0691350B1 (de) 2002-05-02
CA2153208A1 (en) 1996-01-09
DE69526542T2 (de) 2003-01-09
DE69526542D1 (de) 2002-06-06
ES2176302T3 (es) 2002-12-01

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Legal Events

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