ATE217544T1 - Verfahren und vorrichtung zur untersuchung von teilchen durch dielektrophorese - Google Patents

Verfahren und vorrichtung zur untersuchung von teilchen durch dielektrophorese

Info

Publication number
ATE217544T1
ATE217544T1 AT97933756T AT97933756T ATE217544T1 AT E217544 T1 ATE217544 T1 AT E217544T1 AT 97933756 T AT97933756 T AT 97933756T AT 97933756 T AT97933756 T AT 97933756T AT E217544 T1 ATE217544 T1 AT E217544T1
Authority
AT
Austria
Prior art keywords
particles
behavior
dielectrophoresis
different
spectrum
Prior art date
Application number
AT97933756T
Other languages
English (en)
Inventor
Ronald Pethig
Gerardus Hendricus Markx
Original Assignee
Btg Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Btg Int Ltd filed Critical Btg Int Ltd
Application granted granted Critical
Publication of ATE217544T1 publication Critical patent/ATE217544T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C5/00—Separating dispersed particles from liquids by electrostatic effect
    • B03C5/005—Dielectrophoresis, i.e. dielectric particles migrating towards the region of highest field strength

Landscapes

  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Electrostatic Separation (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
AT97933756T 1996-07-26 1997-07-28 Verfahren und vorrichtung zur untersuchung von teilchen durch dielektrophorese ATE217544T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9615775.5A GB9615775D0 (en) 1996-07-26 1996-07-26 Apparatus and method for characterising particles using dielectrophoresis
PCT/GB1997/002011 WO1998004355A1 (en) 1996-07-26 1997-07-28 Apparatus and method for testing particles using dielectrophoresis

Publications (1)

Publication Number Publication Date
ATE217544T1 true ATE217544T1 (de) 2002-06-15

Family

ID=10797580

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97933756T ATE217544T1 (de) 1996-07-26 1997-07-28 Verfahren und vorrichtung zur untersuchung von teilchen durch dielektrophorese

Country Status (8)

Country Link
US (1) US6264815B1 (de)
EP (1) EP0914211B1 (de)
JP (1) JP4105767B2 (de)
AT (1) ATE217544T1 (de)
DE (1) DE69712621T2 (de)
DK (1) DK0914211T3 (de)
GB (1) GB9615775D0 (de)
WO (1) WO1998004355A1 (de)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403367B1 (en) * 1994-07-07 2002-06-11 Nanogen, Inc. Integrated portable biological detection system
US7857957B2 (en) 1994-07-07 2010-12-28 Gamida For Life B.V. Integrated portable biological detection system
CA2255599C (en) 1996-04-25 2006-09-05 Bioarray Solutions, Llc Light-controlled electrokinetic assembly of particles near surfaces
US5748088A (en) * 1996-11-27 1998-05-05 Afilani; Thomas L. Device and method using dielectrokinesis to locate entities
US20030102218A1 (en) * 1997-07-28 2003-06-05 Kiely James Dillon Head-disk stiction reduction
DE19823047C1 (de) * 1998-05-22 1999-08-26 Fuhr Verfahren und Vorrichtung zur Permeation biologischer Objekte
US6749736B1 (en) 1998-06-26 2004-06-15 Evotec Technologies Gmbh Electrode arrangement for the dielectrophoretic diversion of particles
DE19860117A1 (de) * 1998-12-23 2000-07-13 Evotec Biosystems Ag Elektrodenanordnung zur dielektrophoretischen Partikelablenkung
BR9916840A (pt) * 1998-12-23 2001-10-09 Nanogen Inc Sistema de detecção biológica portátil integrado
US6294063B1 (en) 1999-02-12 2001-09-25 Board Of Regents, The University Of Texas System Method and apparatus for programmable fluidic processing
CN1181337C (zh) 2000-08-08 2004-12-22 清华大学 微流体系统中实体分子的操纵方法及相关试剂盒
US6942776B2 (en) * 1999-05-18 2005-09-13 Silicon Biosystems S.R.L. Method and apparatus for the manipulation of particles by means of dielectrophoresis
GB9916851D0 (en) * 1999-07-20 1999-09-22 Univ Wales Bangor Manipulation of particles in liquid media
GB9916850D0 (en) * 1999-07-20 1999-09-22 Univ Wales Bangor Dielectrophoretic apparatus & method
GB2358473B (en) * 2000-01-22 2003-10-08 Cell Analysis Ltd Methods and apparatus for detecting microscopic bodies
JP4587112B2 (ja) * 2000-04-13 2010-11-24 和光純薬工業株式会社 誘電泳動装置及び物質の分離方法
GB2361883B (en) * 2000-05-03 2003-05-28 Cell Analysis Ltd Method and apparatus for analysing low concentrations of particles
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
DE60117556T2 (de) 2000-06-21 2006-11-02 Bioarray Solutions Ltd. Multianalytische molekularanalyse durch verwendung anwendungsspezifischer zufallspartikelarrays
CN100495030C (zh) 2000-09-30 2009-06-03 清华大学 多力操纵装置及其应用
WO2002075276A2 (en) * 2001-03-15 2002-09-26 The Regents Of The University Of California Positioning of organic and inorganic objects by electrophoretic forces including for microlens alignment
US7419574B2 (en) * 2001-06-20 2008-09-02 Cummings Eric B Dielectrophoresis device and method having non-uniform arrays for manipulating particles
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
CA2497740C (en) 2001-10-15 2011-06-21 Bioarray Solutions, Ltd. Multiplexed analysis of polymorphic loci by probe elongation-mediated detection
US6703819B2 (en) 2001-12-03 2004-03-09 Board Of Regents, The University Of Texas System Particle impedance sensor
US6637257B2 (en) * 2002-01-02 2003-10-28 Integrated Sensing Systems Micromachined fluid analysis device and method
US20030209438A1 (en) * 2002-05-09 2003-11-13 Vincent Bressler Particle characterization using gravity in opposition to an induced force
US20040011652A1 (en) * 2002-07-16 2004-01-22 Bressler Vincent Edward Separation of particles using multiple conductive layers
US20040060820A1 (en) * 2002-10-01 2004-04-01 Bressler Vincent Edward Characterization of particles by position in an electric field
AU2003298655A1 (en) 2002-11-15 2004-06-15 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
WO2004055505A1 (en) * 2002-12-12 2004-07-01 Aura Biosystems Inc. Dielectrophoretic particle profiling system and method
US7105081B2 (en) * 2002-12-20 2006-09-12 Board Of Regents, The University Of Texas System Methods and apparatus for electrosmear analysis
JP4128084B2 (ja) * 2003-01-07 2008-07-30 クラスターテクノロジー株式会社 試料の特性化方法およびその装置
US7604718B2 (en) * 2003-02-19 2009-10-20 Bioarray Solutions Ltd. Dynamically configurable electrode formed of pixels
US7169282B2 (en) * 2003-05-13 2007-01-30 Aura Biosystems Inc. Dielectrophoresis apparatus
US7156970B2 (en) * 2003-06-12 2007-01-02 Palo Alto Research Center Incorporated Distributed multi-segmented reconfigurable traveling wave grids for separation of proteins in gel electrophoresis
US7927796B2 (en) 2003-09-18 2011-04-19 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
CA2539824C (en) 2003-09-22 2015-02-03 Xinwen Wang Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
US7347923B2 (en) * 2003-10-03 2008-03-25 Sandia Corporation Dielectrophoresis device and method having insulating ridges for manipulating particles
CA2544041C (en) 2003-10-28 2015-12-08 Bioarray Solutions Ltd. Optimization of gene expression analysis using immobilized capture probes
CA2544202C (en) 2003-10-29 2012-07-24 Bioarray Solutions Ltd. Multiplexed nucleic acid analysis by fragmentation of double-stranded dna
US7384791B2 (en) * 2004-01-21 2008-06-10 Hewlett-Packard Development Company, L.P. Method of analyzing blood
US7390387B2 (en) * 2004-03-25 2008-06-24 Hewlett-Packard Development Company, L.P. Method of sorting cells in series
US7160425B2 (en) * 2004-03-25 2007-01-09 Hewlett-Packard Development Company, L.P. Cell transporter for a biodevice
US7390388B2 (en) * 2004-03-25 2008-06-24 Hewlett-Packard Development Company, L.P. Method of sorting cells on a biodevice
WO2006085905A1 (en) 2004-05-28 2006-08-17 Board Of Regents, The University Of Texas System Programmable fluidic processors
ITBO20040420A1 (it) 2004-07-07 2004-10-07 Type S R L Macchina per taglio e formatura di piattine metalliche
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
ITBO20050481A1 (it) * 2005-07-19 2007-01-20 Silicon Biosystems S R L Metodo ed apparato per la manipolazione e/o l'individuazione di particelle
WO2007046484A1 (ja) * 2005-10-19 2007-04-26 Sharp Kabushiki Kaisha 誘電泳動チップおよび誘電泳動装置並びに誘電泳動システム
JP2009014342A (ja) * 2005-10-19 2009-01-22 Sharp Corp 誘電泳動チップおよび誘電泳動装置並びに誘電泳動システム
ITBO20050646A1 (it) 2005-10-26 2007-04-27 Silicon Biosystem S R L Metodo ed apparato per la caratterizzazione ed il conteggio di particelle
US8262886B2 (en) 2006-02-10 2012-09-11 Kochi University Of Technology Apparatus for analyzing characteristics of particulate with dielectrophoresis of particulate by applying angle-modulated wave and method for the same
JP5186675B2 (ja) * 2006-03-10 2013-04-17 クラスターテクノロジー株式会社 誘電泳動による微粒子の状態の測定方法
ITTO20060226A1 (it) 2006-03-27 2007-09-28 Silicon Biosystem S P A Metodo ed apparato per il processamento e o l'analisi e o la selezione di particelle, in particolare particelle biologiche
EP2042239A1 (de) * 2007-09-10 2009-04-01 Koninklijke Philips Electronics N.V. Dielektrophoretische Vorrichtung und entsprechendes Verfahren für Zellmembran-Studien
JPWO2009037804A1 (ja) * 2007-09-18 2011-01-06 パナソニック株式会社 微粒子測定装置および微粒子測定方法
WO2009044902A1 (ja) * 2007-10-05 2009-04-09 Kyushu Institute Of Technology 誘電泳動装置および方法
ITTO20070771A1 (it) 2007-10-29 2009-04-30 Silicon Biosystems Spa Metodo e apparato per la identificazione e manipolazione di particelle
JP2011516867A (ja) * 2008-04-03 2011-05-26 ザ レジェンツ オブ ザ ユニヴァースティ オブ カリフォルニア 細胞、小胞、ナノ粒子およびバイオマーカーを分離および単離するためのエキソビボの多次元システム
CN101281163B (zh) * 2008-04-28 2012-06-27 中央民族大学 用于确定多种细胞介电响应和分离条件的检测系统
IT1391619B1 (it) 2008-11-04 2012-01-11 Silicon Biosystems Spa Metodo per l'individuazione, selezione e analisi di cellule tumorali
US10895575B2 (en) 2008-11-04 2021-01-19 Menarini Silicon Biosystems S.P.A. Method for identification, selection and analysis of tumour cells
JP5834001B2 (ja) 2009-03-17 2015-12-16 シリコン・バイオシステムズ・ソシエタ・ペル・アチオニ 細胞を分離するためのマイクロ流体デバイス
JP2010252785A (ja) 2009-03-31 2010-11-11 Kanagawa Acad Of Sci & Technol 細胞濃縮分離装置
JP5471228B2 (ja) * 2009-09-17 2014-04-16 パナソニック株式会社 微生物濃度調整装置
IT1403518B1 (it) 2010-12-22 2013-10-31 Silicon Biosystems Spa Dispositivo microfluidico per la manipolazione di particelle
ITTO20110990A1 (it) 2011-10-28 2013-04-29 Silicon Biosystems Spa Metodo ed apparato per l'analisi ottica di particelle a basse temperature
US11198126B2 (en) 2011-10-31 2021-12-14 Fluid-Screen, Inc. Apparatus for pathogen detection
ITBO20110766A1 (it) 2011-12-28 2013-06-29 Silicon Biosystems Spa Dispositivi, apparato, kit e metodo per il trattamento di un campione biologico
US8932815B2 (en) 2012-04-16 2015-01-13 Biological Dynamics, Inc. Nucleic acid sample preparation
JP2015519886A (ja) 2012-04-16 2015-07-16 バイオロジカル ダイナミクス，インク． 核酸サンプル調製
KR101501983B1 (ko) * 2013-06-05 2015-03-13 한국항공대학교산학협력단 음의 유전 영동력 기반의 고효율 다단 세포 분리장치
WO2014200774A2 (en) * 2013-06-14 2014-12-18 Nanophoretics Llc Method and apparatus for identifying objects in a plurality of objects using dielectrophoresis
EP3052237A4 (de) * 2013-10-04 2017-06-21 Michigan Technological University Verfahren und systeme zur identifikation eines teilchens durch dielektrophorese
EP3129481A4 (de) 2014-04-08 2017-10-25 Biological Dynamics, Inc. Verbesserte vorrichtungen zur trennung von biologischen materialien
US10488391B2 (en) * 2014-10-31 2019-11-26 The Regents Of The University Of California Neural circuit probe
JP6171124B2 (ja) * 2015-10-07 2017-08-02 株式会社Ａｆｉテクノロジー 検査装置、検査システム、及び検査方法
WO2017165852A1 (en) 2016-03-24 2017-09-28 Biological Dynamics, Inc. Disposable fluidic cartridge and components
PL3442711T3 (pl) * 2016-04-15 2021-11-15 Fluid-Screen, Inc. Sposoby wykrywania analitu oraz urządzenie wykorzystujące dielektroforezę i elektroosmozę
CN118421711A (zh) 2016-10-31 2024-08-02 梅科诺有限公司 用于生物细胞注射的针操纵器的阵列
KR102701901B1 (ko) * 2016-10-31 2024-08-30 미코노스 리미티드 자동화된 생체 세포 주입을 위한 개선된 센싱
WO2018208820A1 (en) 2017-05-08 2018-11-15 Biological Dynamics, Inc. Methods and systems for analyte information processing
WO2019126388A1 (en) 2017-12-19 2019-06-27 Biological Dynamics, Inc. Methods and devices for detection of multiple analytes from a biological sample
WO2019195196A1 (en) 2018-04-02 2019-10-10 Biological Dynamics, Inc. Dielectric materials
SG11202111945VA (en) 2019-06-13 2021-11-29 Mekonos Inc Micro-electro-mechanical-system structures and applications thereof
EP4058055A4 (de) 2019-11-13 2023-12-13 Fluid-Screen, Inc. Vorrichtung und verfahren zur schnellen detektion, trennung, reinigung und quantifizierung verschiedener viren aus zellen, kulturmedien und anderen flüssigkeiten
CA3161454A1 (en) 2019-11-13 2021-05-20 Fluid-Screen, Inc. Methods and apparatus for detection of bacteria in a sample using dielectrophoresis
CN119546556A (zh) * 2022-07-12 2025-02-28 诺科利公司 用于表征水中的有机活颗粒类型的方法和系统

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4326934A (en) 1979-12-31 1982-04-27 Pohl Herbert A Continuous dielectrophoretic cell classification method
US4956065A (en) 1988-11-03 1990-09-11 Kaler Karen V I S Method and apparatus for three dimensional dynamic dielectric levitation
GB9002092D0 (en) * 1990-01-30 1990-03-28 P & B Sciences Ltd Manipulation of solid,semi-solid or liquid materials
DE4034697A1 (de) * 1990-10-31 1992-05-14 Fraunhofer Ges Forschung Verfahren zur handhabung mikroskopisch kleiner, dielektrischer teilchen und vorrichtung zur durchfuehrung des verfahrens
DE4127405C2 (de) * 1991-08-19 1996-02-29 Fraunhofer Ges Forschung Verfahren zur Trennung von Gemischen mikroskopisch kleiner, in einer Flüssigkeit oder einem Gel suspendierter dielektrischer Teilchen und Vorrichtung zur Durchführung des Verfahrens
US5489506A (en) * 1992-10-26 1996-02-06 Biolife Systems, Inc. Dielectrophoretic cell stream sorter
GB9306729D0 (en) 1993-03-31 1993-05-26 British Tech Group Improvements in separators

Also Published As

Publication number Publication date
EP0914211A1 (de) 1999-05-12
WO1998004355A1 (en) 1998-02-05
GB9615775D0 (en) 1996-09-04
US6264815B1 (en) 2001-07-24
DE69712621D1 (de) 2002-06-20
JP4105767B2 (ja) 2008-06-25
DK0914211T3 (da) 2002-08-19
JP2001500252A (ja) 2001-01-09
EP0914211B1 (de) 2002-05-15
DE69712621T2 (de) 2002-11-07

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