ATE218527T1 - Verfahren zur herstellung von 6-methyl-2-heptanon analogen, und verfahren zur herstellung von phyton und isophytol - Google Patents

Verfahren zur herstellung von 6-methyl-2-heptanon analogen, und verfahren zur herstellung von phyton und isophytol

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Publication number
ATE218527T1
ATE218527T1 AT97111203T AT97111203T ATE218527T1 AT E218527 T1 ATE218527 T1 AT E218527T1 AT 97111203 T AT97111203 T AT 97111203T AT 97111203 T AT97111203 T AT 97111203T AT E218527 T1 ATE218527 T1 AT E218527T1
Authority
AT
Austria
Prior art keywords
producing
methyl
isophytol
phyton
heptanone
Prior art date
Application number
AT97111203T
Other languages
English (en)
Inventor
Yoichi Kido
Noriaki Kumagai
Hideharu Iwasaki
Takashi Onishi
Fuyuo Ueyama
Original Assignee
Kuraray Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP19548096A external-priority patent/JP3805435B2/ja
Priority claimed from JP35221496A external-priority patent/JP3882245B2/ja
Application filed by Kuraray Co filed Critical Kuraray Co
Application granted granted Critical
Publication of ATE218527T1 publication Critical patent/ATE218527T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/17—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds
    • C07C29/172—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds with the obtention of a fully saturated alcohol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/42—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing triple carbon-to-carbon bonds, e.g. with metal-alkynes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/513—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C07C45/676—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton by elimination of carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/73—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with hydrogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/203—Unsaturated compounds containing keto groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT97111203T 1996-07-05 1997-07-03 Verfahren zur herstellung von 6-methyl-2-heptanon analogen, und verfahren zur herstellung von phyton und isophytol ATE218527T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP19548096A JP3805435B2 (ja) 1996-07-05 1996-07-05 ６−メチル−３−ヘプテン−２−オンの製造方法
JP35221496A JP3882245B2 (ja) 1996-12-11 1996-12-11 フィトン及びイソフィトールの製造方法
JP5135697 1997-03-06

Publications (1)

Publication Number Publication Date
ATE218527T1 true ATE218527T1 (de) 2002-06-15

Family

ID=27294287

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97111203T ATE218527T1 (de) 1996-07-05 1997-07-03 Verfahren zur herstellung von 6-methyl-2-heptanon analogen, und verfahren zur herstellung von phyton und isophytol

Country Status (6)

Country Link
US (2) US5955636A (de)
EP (2) EP0816321B1 (de)
KR (1) KR100570474B1 (de)
CN (2) CN1125805C (de)
AT (1) ATE218527T1 (de)
DE (2) DE69712984T2 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19959053A1 (de) * 1999-12-07 2001-06-13 Basf Ag Verfahren zur Herstellung von Ketonen, insbesondere von 6-Methylheptan-2-on
KR20010083487A (ko) * 2000-02-15 2001-09-01 구광시 소팔콘의 제조방법
DE10044390A1 (de) * 2000-09-08 2002-03-21 Degussa Verfahren zur Herstellung von 6-Methylheptanon
DE10106186A1 (de) 2001-02-10 2002-08-14 Oxeno Olefinchemie Gmbh Verfahren zur Kondensation von Aldehyden mit Ketonen mittels Mehrphasenreaktion
DE10111071A1 (de) * 2001-03-08 2002-09-19 Degussa Verfahren zur Herstellung von Methylketonen
DE10112099A1 (de) * 2001-03-14 2002-09-19 Degussa Verbessertes Verfahren zur Herstellung von 6-Methylheptanon
DE10123066A1 (de) * 2001-05-11 2002-11-14 Basf Ag Verfahren zur Herstellung von höheren alpha,beta-ungesättigten Alkoholen
DE10149349A1 (de) * 2001-10-06 2003-04-17 Oxeno Olefinchemie Gmbh Verfahren zur Herstellung von 6-Methylheptan-2-on und dessen Verwendung
ITMI20012267A1 (it) * 2001-10-29 2003-04-29 Chemi Spa Preparazione ed uso di un catalizzatore eterogeneo per l'idrogenerazione di un doppio legame di un composto carbonilico b-insaturo
EP1327620A1 (de) * 2002-01-14 2003-07-16 Aventis Animal Nutrition S.A. Verfahren zur Herstellung von Phyton
US6979751B2 (en) * 2002-12-23 2005-12-27 Eastman Chemical Company Processes for the preparation of higher molecular weight ketones
US6960694B2 (en) * 2003-07-01 2005-11-01 Eastman Chemical Company Processes for preparing β-hydroxy-ketones and α,β-unsaturated ketones
US7071361B2 (en) 2004-06-25 2006-07-04 Fastman Chemical Company Processes for the preparation of high molecular weight saturated ketones
EP1963246B1 (de) 2005-12-20 2017-08-23 DSM IP Assets B.V. Verfahren zur herstellung von ubichinon-zwischenprodukten
TWI492755B (zh) * 2009-12-30 2015-07-21 Metal Ind Res & Dev Ct 抗糖尿病及抗新陳代謝疾病之香椿超臨界萃取物、製備方法及用途
US8546621B2 (en) * 2010-08-24 2013-10-01 Dsm Ip Assets B.V. Process for the manufacture of 3,7-dimethyl-1-octen-3-ol
BR112013004208B1 (pt) * 2010-08-24 2019-02-26 Dsm Ip Assets B.V. Processos para a fabricação de 3,7-dimetil-l-octeno-3-ol, de fitol ou isofitol, e de vitamina e ou o seu acetato
CN102821771B (zh) * 2010-12-28 2015-01-14 高雄医学大学 抗糖尿病及抗新陈代谢疾病的香椿超临界萃取物、制备方法及用途
US9611200B2 (en) 2012-12-18 2017-04-04 Dsm Ip Assets B.V. (6R,10R)-6,10,14-trimetylpentadecan-2-one prepared from 6,10,14 trimetylpentadeca-5,9,13-trien-2-one or 6,10,14-trimetylpentadeca-5,9-dien-2-one
CN109970533B (zh) * 2012-12-18 2022-06-14 帝斯曼知识产权资产管理有限公司 由(r)-6，10，14-三甲基十五碳-5-烯-2-酮制备的(6r，10r)-6，10，14-三甲基十五烷-2-酮
JP6481171B2 (ja) * 2012-12-18 2019-03-13 ディーエスエム アイピー アセッツ ビー．ブイ．Ｄｓｍ Ｉｐ Ａｓｓｅｔｓ Ｂ．Ｖ． ６，１０−ジメチルウンデカ−５−エン−２−オンまたは６，１０−ジメチルウンデカ−５，９−ジエン−２−オンから調製した（６ｒ，１０ｒ）−６，１０，１４−トリメチルペンタデカン−２−オン
CN105037120B (zh) * 2015-05-25 2016-09-21 吉林北沙制药有限公司 一种甲基庚酮的新型合成方法
WO2017098050A1 (en) * 2015-12-11 2017-06-15 Dsm Ip Assets B.V. Process for the manufacture of 6,10,14-trimethylpentadecan-2-one, isophytol and alpha-tocopherol
CN105399613B (zh) * 2015-12-31 2018-09-25 山东新和成药业有限公司 一种香料6-甲基-3-庚烯-2-酮的制备方法
CN107673959B (zh) * 2017-10-27 2019-10-11 西南化工研究设计院有限公司 一种制备甲基庚烯酮的方法和系统
CN109651118A (zh) * 2018-12-25 2019-04-19 万华化学集团股份有限公司 一种植酮的制备方法
CN111995512B (zh) * 2019-05-27 2023-11-10 四川海思科制药有限公司 一种全消旋植物醇组合物及其制备方法和应用
CN111018672B (zh) * 2019-12-09 2023-01-13 万华化学集团股份有限公司 一种制备芳樟醇的方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2485989A (en) * 1946-02-09 1949-10-25 Commercial Solvents Corp Process for converting lower-boiling aldehydes into higher-boiling aldehydes
US2499172A (en) * 1946-02-09 1950-02-28 Commercial Solvents Corp Process for converting lower-boiling ketones into higher-boiling ketones
DE823291C (de) * 1950-03-07 1951-12-03 Basf Ag Verfahren zur Herstellung von gesaettigten Ketonen
US2719863A (en) * 1952-07-16 1955-10-04 Du Pont Aldol condensation of ketones
US2792421A (en) * 1953-08-21 1957-05-14 Distillers Co Yeast Ltd Condensation reaction
US2809215A (en) * 1954-09-30 1957-10-08 Hoffmann La Roche Higher aliphatic ketone
GB907142A (en) * 1959-01-14 1962-10-03 Distillers Co Yeast Ltd Production of unsaturated ketones
US3082260A (en) * 1959-05-20 1963-03-19 Air Reduction Preparation of acetylenic alcohols
US3496240A (en) * 1966-09-20 1970-02-17 Hoffmann La Roche Acetylenic carbinol production and recovery by thin film,superatmospheric pressure evaporation with condenser pressure control by venting
BE789849A (fr) * 1971-10-13 1973-04-09 Basf Ag Procede de preparation de cetones alpha-ethyleniques
JPS4925251A (de) * 1972-06-29 1974-03-06
JPS5249444B2 (de) * 1973-06-26 1977-12-17
DE2445133A1 (de) * 1973-10-01 1975-04-03 Hoffmann La Roche Verfahren zur herstellung von aethinylcarbinolen
IT1085879B (it) * 1976-04-08 1985-05-28 Basf Ag Processo per la preparazione di chetoni superiori
DE2839474A1 (de) * 1978-09-11 1980-03-27 Basf Ag Verfahren zur herstellung von carbonylverbindungen
DE2928944A1 (de) * 1979-07-18 1981-02-12 Basf Ag Verbessertes verfahren zur herstellung von hoeheren ungesaettigten ketonen
US4701562A (en) * 1986-06-25 1987-10-20 Union Carbide Corporation Process for the condensation of aldehydes
RO94314B1 (ro) * 1986-06-28 1988-05-01 Institutul De Cercetari Chimice Procedeu de preparare a izofitolului
ATE181909T1 (de) * 1995-04-04 1999-07-15 Kuraray Co Verfahren zur herstellung von 6-methylheptan-2-on

Also Published As

Publication number Publication date
EP0816321B1 (de) 2002-06-05
DE69712984D1 (de) 2002-07-11
DE69712984T2 (de) 2003-01-16
EP1122236B1 (de) 2004-09-29
EP1122236A2 (de) 2001-08-08
DE69731007D1 (de) 2004-11-04
DE69731007T2 (de) 2006-02-23
EP0816321A1 (de) 1998-01-07
US6232506B1 (en) 2001-05-15
KR100570474B1 (ko) 2006-04-12
EP1122236A3 (de) 2001-08-16
CN1125805C (zh) 2003-10-29
CN1178784A (zh) 1998-04-15
CN1393435A (zh) 2003-01-29
CN1250507C (zh) 2006-04-12
US5955636A (en) 1999-09-21

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