ATE219040T1 - Verfahren zur herstellung von sevoflurane - Google Patents

Verfahren zur herstellung von sevoflurane

Info

Publication number: ATE219040T1
Authority: AT; Austria
Prior art keywords: producing sevoflurane; sevoflurane; producing; mixture; 2choch2cl
Prior art date: 1997-08-18

Application number

AT98306585T

Other languages

English (en)

Inventor

Ross Clark Terrell

Original Assignee

Medeva Pharmaceuticals Pa Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-08-18

Filing date

1998-08-18

Publication date

2002-06-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25432067&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE219040(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1998-08-18 Application filed by Medeva Pharmaceuticals Pa Inc filed Critical Medeva Pharmaceuticals Pa Inc

2002-06-15 Application granted granted Critical

2002-06-15 Publication of ATE219040T1 publication Critical patent/ATE219040T1/de

Links

DFEYYRMXOJXZRJ-UHFFFAOYSA-N sevoflurane Chemical compound FCOC(C(F)(F)F)C(F)(F)F DFEYYRMXOJXZRJ-UHFFFAOYSA-N 0.000 title abstract 3
229960002078 sevoflurane Drugs 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
239000000203 mixture Substances 0.000 abstract 2
HHYFUCXZHKDNPT-UHFFFAOYSA-N 2-(chloromethoxy)-1,1,1,3,3,3-hexafluoropropane Chemical compound FC(F)(F)C(C(F)(F)F)OCCl HHYFUCXZHKDNPT-UHFFFAOYSA-N 0.000 abstract 1
KRHYYFGTRYWZRS-UHFFFAOYSA-N Fluorane Chemical compound F KRHYYFGTRYWZRS-UHFFFAOYSA-N 0.000 abstract 1
150000001412 amines Chemical class 0.000 abstract 1
229910000040 hydrogen fluoride Inorganic materials 0.000 abstract 1
239000007788 liquid Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/22—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Artificial Filaments (AREA)
Polyesters Or Polycarbonates (AREA)

AT98306585T 1997-08-18 1998-08-18 Verfahren zur herstellung von sevoflurane ATE219040T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US08/912,520 US5969193A (en)	1997-08-18	1997-08-18	Method for the preparation of sevoflurane

Publications (1)

Publication Number	Publication Date
ATE219040T1 true ATE219040T1 (de)	2002-06-15

Family

ID=25432067

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98306585T ATE219040T1 (de)	1997-08-18	1998-08-18	Verfahren zur herstellung von sevoflurane

Country Status (6)

Country	Link
US (4)	US5969193A (de)
EP (1)	EP0901999B1 (de)
JP (1)	JP4166870B2 (de)
AT (1)	ATE219040T1 (de)
DE (1)	DE69805926T2 (de)
ES (1)	ES2155278T3 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL125649A (en) *	1996-03-08	2002-12-01	Motorola Inc	Method and device for detecting signal of a sound sampled from noise
US5969193A (en) *	1997-08-18	1999-10-19	Medeva Pharmaceuticals Pa, Inc.	Method for the preparation of sevoflurane
US6100434A (en) *	1999-03-26	2000-08-08	Abbott Laboratories	Method for synthesizing sevoflurane and an intermediate thereof
AU7511300A (en)	1999-09-04	2001-04-10	Solvay Fluor Und Derivate Gmbh	Regeneration of onium fluoride-hf adducts
US6469219B1 (en)	2000-03-16	2002-10-22	Halocarbon Products Corporation	Production of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
US6245949B1 (en) *	2000-06-01	2001-06-12	Abbott Laboratories	Synthetic method for the fluoromethylation of alcohols
US6271422B1 (en) *	2000-06-01	2001-08-07	Abbott Laboratories	Method for fluoromethylation of alcohols via halogenative decarboxylation
BRPI0506698A (pt) *	2004-01-05	2007-05-02	Halocarbon Prod Corp	método cromatográfico para a análise tanto no processo quanto no sevoflurano acabado
US20060258755A1 (en) *	2005-04-18	2006-11-16	Terrell Ross C	Preparation of sevoflurane with negligible water content
DK1910258T3 (da)	2005-08-04	2012-05-07	Halocarbon Prod Corp	Oprensning af fluormethyl-1,1,1,3,3,3-hexafluorisopropylether (sevofluran)
JP5315609B2 (ja)	2006-06-05	2013-10-16	ダイキン工業株式会社	新規カルボン酸化合物、その用途及びその製造方法
JP5114880B2 (ja) *	2006-07-06	2013-01-09	ダイキン工業株式会社	新規α−フルオロメトキシカルボン酸エステル、該α−フルオロメトキシカルボン酸エステルの製造方法及びセボフルランの製造方法
RU2368597C2 (ru) *	2007-08-06	2009-09-27	Закрытое акционерное общество Научно-производственное объединение "ПиМ-Инвест"	Двухстадийный способ получения 2-(фторметокси)-1,1,1,3,3,3-гексафторизопропана (севофлурана)
JP5163064B2 (ja) *	2007-11-13	2013-03-13	ダイキン工業株式会社	新規カルボン酸エステル、その用途及びその製造方法
US20090275785A1 (en) *	2008-05-01	2009-11-05	Barry Jones	Distillation Method For The Purification Of Sevoflurane And The Maintenance Of Certain Equipment That May Be Used In The Distillation Process
CN102498085A (zh)	2009-08-10	2012-06-13	苏威氟有限公司	用于制造七氟烷的方法
US9102604B1 (en)	2010-02-15	2015-08-11	Baxter International Inc.	Methods for cleaning distilling columns
WO2012107438A1 (en)	2011-02-10	2012-08-16	Solvay Sa	Process for the manufacture of fluoromethoxymalonic acid derivatives
US8729313B2 (en)	2011-08-15	2014-05-20	Baxter International Inc.	Process for the manufacturing of sevoflurane
RU2479566C1 (ru) *	2012-01-11	2013-04-20	Общество с ограниченной ответственностью "Пермская химическая компания"	Способ получения севофлурана
CN103804151A (zh) *	2012-11-07	2014-05-21	东莞市长安东阳光铝业研发有限公司	一种七氟醚的制备方法
CN103173889B (zh) *	2013-04-16	2015-01-14	江苏江南高纤股份有限公司	仿羊毛涤纶短纤维及其制备方法
RU2656210C1 (ru) *	2017-10-17	2018-06-01	Федеральное государственное унитарное предприятие "Российский научный центр "Прикладная химия"	Способ получения 2-(фторметокси)-1,1,1,3,3,3-гексафторизопропана (севофлурана)
CN113943214B (zh) *	2021-11-11	2023-12-19	福建海西联合药业有限公司	一种运用于七氟烷生产的工艺
WO2025041740A1 (ja) *	2023-08-21	2025-02-27	セントラル硝子株式会社	組成物、脱水剤及び脱水方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3911024A (en) *	1966-12-08	1975-10-07	Louise S Croix	Fluorinated isopropyl derivatives
US3683092A (en) *	1970-07-31	1972-08-08	Baxter Laboratories Inc	Method of anesthesia
US3897502A (en) *	1971-10-22	1975-07-29	Airco Inc	Process for making fluorinated ethers
DE2823969A1 (de) *	1978-06-01	1979-12-13	Hoechst Ag	Verfahren zur herstellung organischer fluorverbindungen
US4250334A (en) *	1979-12-26	1981-02-10	Baxter Travenol Laboratories, Inc.	Method of synthesizing fluoromethylhexafluoroisopropyl ether
US4328376A (en) *	1980-03-31	1982-05-04	Baxter Travenol Laboratories, Inc.	Method of removing fluorinated olefin byproduct formed during the synthesis of a fluorinated ether
US4874901A (en) *	1988-05-06	1989-10-17	Boc, Inc.	Process for the production of polyfluorinated ethers
US4874902A (en) *	1988-05-20	1989-10-17	Boc, Inc.	Method for the preparation of fluoromethyl 1,1,1,3,3,3-hexafluoro-2-propyl ether
US4996371A (en) *	1990-01-16	1991-02-26	Boc, Inc.	Method for fluorodecarboxylation
GB9023370D0 (en) *	1990-10-26	1990-12-05	Rhone Poulenc Chemicals	Synthesis of fluorinated substituted ethanes
US5969193A (en) *	1997-08-18	1999-10-19	Medeva Pharmaceuticals Pa, Inc.	Method for the preparation of sevoflurane
US5886239A (en) *	1997-11-21	1999-03-23	Baxter International Inc.	Method of preparing monofluoromethyl ethers

1997
- 1997-08-18 US US08/912,520 patent/US5969193A/en not_active Expired - Lifetime
1998
- 1998-08-18 AT AT98306585T patent/ATE219040T1/de not_active IP Right Cessation
- 1998-08-18 EP EP98306585A patent/EP0901999B1/de not_active Revoked
- 1998-08-18 JP JP23131898A patent/JP4166870B2/ja not_active Expired - Fee Related
- 1998-08-18 DE DE69805926T patent/DE69805926T2/de not_active Revoked
- 1998-08-26 ES ES98306858T patent/ES2155278T3/es not_active Expired - Lifetime
1999
- 1999-06-21 US US09/337,019 patent/US20010056213A1/en not_active Abandoned
2002
- 2002-07-11 US US10/193,786 patent/US20020177739A1/en not_active Abandoned
2003
- 2003-08-20 US US10/644,500 patent/US7202386B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JPH11116521A (ja)	1999-04-27
US20020177739A1 (en)	2002-11-28
JP4166870B2 (ja)	2008-10-15
ES2155278T3 (es)	2001-05-01
EP0901999B1 (de)	2002-06-12
DE69805926D1 (de)	2002-07-18
US20040087817A1 (en)	2004-05-06
US5969193A (en)	1999-10-19
US7202386B2 (en)	2007-04-10
DE69805926T2 (de)	2002-09-26
US20010056213A1 (en)	2001-12-27
EP0901999A1 (de)	1999-03-17

Legal Events

Date	Code	Title	Description
2002-12-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE219040T1 (de)	2002-06-15	Verfahren zur herstellung von sevoflurane
DE69509920D1 (de)	1999-07-01	Verfahren zur herstellung von allyl-ether-, -thioether- und -amin-verbindungen
DE69716767D1 (de)	2002-12-05	Verfahren zur herstellung von tolterodin
DE69522479D1 (de)	2001-10-04	Verfahren zur herstellung von terephtalischer säure
DE59811659D1 (de)	2004-08-19	Verfahren zur Herstellung eines Metallocen-Katalysatorsystems
ATE61575T1 (de)	1991-03-15	Verfahren zur herstellung von nfluorsulfonamiden.
DE59309420D1 (de)	1999-04-15	Verfahren zur kontinuierlichen Herstellung von Flüssigsiliconkautschuken
ATE449056T1 (de)	2009-12-15	Verfahren zur herstellung von fluorierten vinylethern
ATE210631T1 (de)	2001-12-15	Verfahren zur herstellung von iohexol
ATE214686T1 (de)	2002-04-15	Verfahren zur herstellung von fluorverbindungen aus den entsprechenden aminen
DE3581464D1 (de)	1991-02-28	Verfahren zur herstellung optisch aktiver amine.
DE59307795D1 (de)	1998-01-15	Verfahren zur herstellung von rückstandsfreiem 2,4/2,6-diaminotoluolgemisch
DE69529975D1 (de)	2003-04-24	Verfahren zur herstellung von bis(4-alkylthiophenyl)disulfid
ATE231492T1 (de)	2003-02-15	Verfahren zur herstellung von pyrrolamiden
DE69719628D1 (de)	2003-04-17	Verfahren zur Herstellung von Bis-(2-hydroxyphenyl-3-benzotriazol)-methanen
DE59804900D1 (de)	2002-08-29	Verfahren zur herstellung von cycloaliphatische gruppen enthaltenden alkoholen
DE3766648D1 (de)	1991-01-24	Katalytisches verfahren zur herstellung von silakohlenwasserstoffen.
ATE181047T1 (de)	1999-06-15	Verfahren zur herstellung von 1,1,1-trifluorethan
ATE213734T1 (de)	2002-03-15	Verfahren zur herstellung von 1,3- disubstituierten 2-nitroguanidinen
ATE224901T1 (de)	2002-10-15	Verfahren zur herstellung von 5-brom-2- fluorbenzolboronsäure
DE3870022D1 (de)	1992-05-21	Verfahren zur herstellung einer wasserstoff enthaltenden mischung.
DE59405089D1 (de)	1998-02-26	Verfahren zur Herstellung von 4,5-Difluorbenzaldehyden
ATE207482T1 (de)	2001-11-15	Verfahren zur herstellung von n2-arylsulfonyl-l- argininamiden
ATE248808T1 (de)	2003-09-15	Verfahren zur herstellung von aminocyanacetamid
ATE238261T1 (de)	2003-05-15	Verfahren zur herstellung von orthoestern