ATE219103T1 - Cnp-analoge peptide und ihre verwendung - Google Patents

Cnp-analoge peptide und ihre verwendung

Info

Publication number: ATE219103T1
Authority: AT; Austria
Prior art keywords: ser; arg; gly; phe; leu
Prior art date: 1991-01-31

Application number

AT92101621T

Other languages

English (en)

Inventor

Shoji Tanaka

Yoshiharu Minamitake

Yasuo Kitajima

Mayumi Furuya

Hisayuki Matsuo

Original Assignee

Suntory Ltd

Hisayuki Matsuo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-01-31

Filing date

1992-01-31

Publication date

2002-06-15

1992-01-31 Application filed by Suntory Ltd, Hisayuki Matsuo filed Critical Suntory Ltd

2002-06-15 Application granted granted Critical

2002-06-15 Publication of ATE219103T1 publication Critical patent/ATE219103T1/de

Links

102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 abstract 2
DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
101800000060 C-type natriuretic peptide Proteins 0.000 abstract 1
102400001025 CNP-22 Human genes 0.000 abstract 1
101800000457 CNP-22 Proteins 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
239000004615 ingredient Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
210000004509 vascular smooth muscle cell Anatomy 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Toxicology (AREA)
Genetics & Genomics (AREA)
Endocrinology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Cardiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT92101621T 1991-01-31 1992-01-31 Cnp-analoge peptide und ihre verwendung ATE219103T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP1132191		1991-01-31
JP3254066A JP2809533B2 (ja)	1991-01-31	1991-06-28	Ｃｎｐ類似体ペプチド

Publications (1)

Publication Number	Publication Date
ATE219103T1 true ATE219103T1 (de)	2002-06-15

Family

ID=26346733

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92101621T ATE219103T1 (de)	1991-01-31	1992-01-31	Cnp-analoge peptide und ihre verwendung

Country Status (6)

Country	Link
US (1)	US5434133A (de)
EP (1)	EP0497368B1 (de)
JP (1)	JP2809533B2 (de)
AT (1)	ATE219103T1 (de)
DE (1)	DE69232636T2 (de)
ES (1)	ES2178634T3 (de)

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DE19903087A1 (de) *	1999-01-27	2000-08-10	Forssmann Wolf Georg	Behandlung von erektilen Dysfunktionen mit C-Typ Natriuretischem Polypeptid (CNP) als Monotherapie oder in Kombination mit Phosphodiesterasehemmern
IL142118A0 (en) *	2001-03-20	2002-03-10	Prochon Biotech Ltd	Method and composition for treatment of skeletal dysplasias
BRPI0203172B8 (pt)	2001-09-28	2021-05-25	Nakao Kazuwa	composição farmacêutica para acondroplasia
WO2004087059A2 (en) *	2003-03-26	2004-10-14	The University Of Texas	Covalent attachment of ligands to nucleophilic proteins guided by non-covalent binding
CN101208353B (zh) *	2003-06-20	2011-12-14	梅约医学教育与研究基金会	脑利尿钠肽的同种型
ES2465141T3 (es) *	2004-03-31	2014-06-05	Kazuwa Nakao	Remedio o medicamento preventivo para la artritis
KR20070007842A (ko)	2004-03-31	2007-01-16	카즈와 나카오	신장증가용 조성물
PL1759001T3 (pl)	2004-04-21	2011-09-30	Alexion Pharma Inc	Koniugaty dostarczane do kości i sposób ich zastosowania do nakierowywania białek do kości
US8580746B2 (en)	2006-03-30	2013-11-12	Palatin Technologies, Inc.	Amide linkage cyclic natriuretic peptide constructs
AU2007233116B2 (en)	2006-03-30	2013-05-09	Palatin Technologies, Inc.	Cyclic natriuretic peptide constructs
AU2007233123A1 (en)	2006-03-30	2007-10-11	Palatin Technologies, Inc.	Linear natriuretic peptide constructs
US8324162B2 (en)	2006-08-08	2012-12-04	Mayo Foundation For Medical Education And Research	Diuretic and natriuretic polypeptides lacking the blood pressure lowering property
EP2171053B1 (de) *	2007-07-20	2014-04-23	Mayo Foundation for Medical Education and Research	Natriuretische polypeptide
WO2009046873A1 (en) *	2007-09-11	2009-04-16	Mondobiotech Laboratories Ag	Combined use of vasonatrin and gastrin-i as a therapeutic agent
WO2009036448A2 (en) *	2007-09-15	2009-03-19	Mayo Foundation For Medical Education And Research	Natriuretic peptide receptor-c agonists
AR069409A1 (es) *	2007-11-21	2010-01-20	Biomarin Pharm Inc	Variantes de peptidos natriureticos de tipo c
WO2009086126A2 (en) *	2007-12-21	2009-07-09	Mayo Foundation For Medical Education And Research	Natriuretic polypeptides
EP2432489B1 (de)	2009-05-20	2016-10-05	BioMarin Pharmaceutical Inc.	Varianten des natriuretischen peptids typ c
EP2457581B1 (de)	2009-07-23	2014-01-08	Igisu Co., Ltd.	Zusammensetzung enthaltend cnp oder bnp für ein externes hautpräparat zur behandlung von dermatitis
WO2011024973A1 (ja) *	2009-08-27	2011-03-03	株式会社イギス	鼻炎治療剤
WO2012013597A1 (de) *	2010-07-28	2012-02-02	Justus-Liebig-Universität Giessen	Stoffe und deren verwendung zur beeinflussung natriuretischer peptidrezeptoren
JP6055779B2 (ja)	2010-12-27	2016-12-27	アレクシオンファーマシューティカルズ，インコーポレイテッド	ナトリウム利尿ペプチドを含む組成物およびその使用方法
BR112013018679B1 (pt)	2011-01-21	2022-04-12	Igisu Co. Ltd.	Agente para o tratamento da alopecia e uso de um peptídeo natriurético do tipo c
EP3189835B1 (de) *	2011-02-28	2018-07-25	National Cerebral and Cardiovascular Center	Medizinischer wirkstoff zur hemmung maligner tumormetastasen
CN103906761B (zh)	2011-08-30	2016-12-21	梅约医学教育与研究基金会	利钠多肽
KR20140084201A (ko)	2011-10-19	2014-07-04	알렉시온 파마 홀딩	알칼리성 포스파타제 및/또는 나트륨이뇨 펩티드를 포함하는 조성물 및 그의 사용 방법
WO2013103896A1 (en)	2012-01-06	2013-07-11	Mayo Foundation For Medical Education And Research	Treating cardiovascular or renal diseases
US10052366B2 (en)	2012-05-21	2018-08-21	Alexion Pharmaceuticsl, Inc.	Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof
CN104059154B (zh) *	2014-05-06	2017-09-29	中国人民解放军第四军医大学	一种新的具有抗心力衰竭作用的钠尿肽嵌合体cnaac
WO2016007873A1 (en)	2014-07-11	2016-01-14	The Regents Of The University Of Michigan	Compositions and methods for treating craniosynostosis
JP6787894B2 (ja)	2014-12-05	2020-11-18	アレクシオンファーマシューティカルズ，インコーポレイテッド	組換えアルカリホスファターゼを用いた発作の処置
CA2973883A1 (en)	2015-01-28	2016-08-04	Alexion Pharmaceuticals, Inc.	Methods of treating a subject with an alkaline phosphatase deficiency
PT3328416T (pt)	2015-07-30	2024-04-10	Biomarin Pharm Inc	Utilização de variantes do péptido natriurético de tipo c para tratar as displasias esqueléticas
EP3689897A1 (de)	2015-07-31	2020-08-05	Igisu Co., Ltd.	Cnp-cyclisches peptid und ein medikament, externes präparat und kosmetikum mit dem cyclischem peptid
JP6993961B2 (ja)	2015-08-17	2022-01-14	アレクシオンファーマシューティカルズ，インコーポレイテッド	アルカリホスファターゼの製造
EP3355904A4 (de)	2015-09-28	2019-06-12	Alexion Pharmaceuticals, Inc.	Identifizierung wirksamer dosierungsschemata für gewebeunspezifische alkalische phosphatase-enzymersatztherapie von hypophosphatasie
EP3368062A4 (de)	2015-10-30	2019-07-03	Alexion Pharmaceuticals, Inc.	Verfahren zur behandlung von craniosynostose bei einem patienten
DK3386531T3 (da)	2015-12-08	2022-01-03	Biomarin Pharm Inc	Anvendelse af c-type natriuretiske peptidvarianter til behandling af osteoarthritis
US11065306B2 (en)	2016-03-08	2021-07-20	Alexion Pharmaceuticals, Inc.	Methods for treating hypophosphatasia in children
KR20180125979A (ko)	2016-04-01	2018-11-26	알렉시온 파마슈티칼스, 인코포레이티드	알칼리성 포스파타아제로 근육 약화의 치료
US10898549B2 (en)	2016-04-01	2021-01-26	Alexion Pharmaceuticals, Inc.	Methods for treating hypophosphatasia in adolescents and adults
WO2017214130A1 (en)	2016-06-06	2017-12-14	Alexion Pharmaceuticals, Inc.	Metal impact on manufacturing of alkaline phosphatases
JP7018933B2 (ja)	2016-08-18	2022-02-14	アレクシオンファーマシューティカルズ，インコーポレイテッド	気管気管支軟化症の治療方法
KR20190129058A (ko)	2017-03-31	2019-11-19	알렉시온 파마슈티칼스, 인코포레이티드	성인 및 청소년에서 저포스파타제증 (hpp)을 치료하는 방법
WO2019190752A1 (en)	2018-03-30	2019-10-03	Alexion Pharmaceuticals, Inc.	Manufacturing of glycoproteins
WO2020033867A2 (en)	2018-08-10	2020-02-13	Alexion Pharmaceuticals, Inc.	Methods of treating neurofibromatosis type 1 and related conditions with alkaline phosphatase
CA3161266A1 (en)	2019-12-09	2021-06-17	Alexion Pharmaceuticals, Inc.	Alkaline phosphatase polypeptides and methods of use thereof
US12611447B2 (en)	2020-09-04	2026-04-28	Alexion Pharmaceuticals, Inc.	Methods for treating bone mineralization disorders
AU2022218782B2 (en)	2021-02-12	2026-06-25	Alexion Pharmaceuticals, Inc.	Alkaline phosphatase polypeptides and methods of use thereof
CN120435308A (zh)	2022-10-21	2025-08-05	伊莱利利公司	长效利尿钠肽及其用途
KR102866559B1 (ko)	2022-11-02	2025-10-02	노보 노르디스크 에이/에스	Cnp 화합물

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US4496544A (en) *	1983-11-10	1985-01-29	Washington University	Atrial Peptides
JPH0672157B2 (ja) *	1984-08-29	1994-09-14	味の素株式会社	新規ペプチド
EP0232078A3 (de) *	1986-01-31	1990-03-14	Merck & Co. Inc.	Peptide mit ANF-Wirkung
EP0292256A3 (de) *	1987-05-19	1990-10-03	Merck & Co. Inc.	Peptide mit ANF-Wirksamkeit
US4935492A (en) *	1987-12-24	1990-06-19	California Biotechnology Inc.	Cyclic analogs of atrial natriuretic peptides
CA1339210C (en) *	1988-05-31	1997-08-05	John Lewicki	Recombinant techniques for production of novel natriuretic and vasodilator peptides
DK380288D0 (da) *	1988-07-07	1988-07-07	Novo Industri As	Hidtil ukendet peptider
US5352770A (en) *	1990-04-20	1994-10-04	Hisayuki Matsuo	Porcine derived novel physiologically active peptide
JP2801079B2 (ja) *	1990-11-14	1998-09-21	サントリー株式会社	Ａｎｐ関連新規ペプチド

1991
- 1991-06-28 JP JP3254066A patent/JP2809533B2/ja not_active Expired - Lifetime
1992
- 1992-01-31 DE DE69232636T patent/DE69232636T2/de not_active Expired - Lifetime
- 1992-01-31 US US07/828,450 patent/US5434133A/en not_active Expired - Lifetime
- 1992-01-31 EP EP92101621A patent/EP0497368B1/de not_active Expired - Lifetime
- 1992-01-31 ES ES92101621T patent/ES2178634T3/es not_active Expired - Lifetime
- 1992-01-31 AT AT92101621T patent/ATE219103T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE69232636D1 (de)	2002-07-18
ES2178634T3 (es)	2003-01-01
JP2809533B2 (ja)	1998-10-08
JPH069688A (ja)	1994-01-18
EP0497368A1 (de)	1992-08-05
EP0497368B1 (de)	2002-06-12
DE69232636T2 (de)	2002-12-05
US5434133A (en)	1995-07-18

Legal Events

Date	Code	Title	Description
2002-12-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69232636D1 (de)	2002-07-18	CNP-Analoge Peptide und ihre Verwendung
AU633913B2 (en)	1993-02-11	Novel tnf-inhibit proteins and their preparation
ATE386118T1 (de)	2008-03-15	Cnp-gen und vorläuferprotein aus schwein
CA2121724A1 (en)	1994-10-22	Methods and compositions for the prophylactic and/or therapeutic treatment of organ hypofunction
CO4750841A1 (es)	1999-03-31	Compuestos ciclicos, inhibidores de la adhesion
WO1998021237A3 (en)	1998-07-30	Peptide compounds useful for modulating FGF receptor activity
ES2054365T3 (es)	1994-08-01	Inhibicion de la via de la regla del n final en celulas vivas.
JPH0532696A (ja)	1993-02-09	副甲状腺ホルモン誘導体
DE69126487D1 (de)	1997-07-17	cDNA für Ratten C-Typ natriuretisches Peptid und Vorläuferprotein
IS2819B (is)	2012-12-15	Viðloðunarsameindir í æðum og mótun á starfsemi@þeirra
DK302388D0 (da)	1988-06-03	Proteiner
TW224975B (de)	1994-06-11
AU682638B2 (en)	1997-10-09	Peptide, bronchodilator and blood flow ameliorant
EP0310887A3 (en)	1990-07-18	Vasoconstrictor peptide
EP0292257A3 (de)	1990-06-06	Peptide mit ANF-Wirksamkeit
EP0330700A4 (de)	1990-01-08	Menschlicher Prourokinase ähnliches Polypeptid.
GB1294771A (en)	1972-11-01	Thyrocalcitonin derivative
ATE124955T1 (de)	1995-07-15	Substrat-peptide.
EP0687685A4 (de)	1998-07-01	Physiologisch-aktive peptide
JPS6426598A (en)	1989-01-27	Calcitonin gene related peptide derivative
KR950011466A (ko)	1995-05-15	선형 결합 억제제
ATE152733T1 (de)	1997-05-15	Bradykinin-antagonisten zur behandlung von akuter pankreatitis
DE453719T1 (de)	1992-04-30	Bakteriozin-peptid.
SE9101586D0 (sv)	1991-05-24	Modified thioredoxin and its use
EP0266006A3 (de)	1990-04-11	Blutdrucksenkende, diuretische Peptide