ATE219103T1 - Cnp-analoge peptide und ihre verwendung - Google Patents

Cnp-analoge peptide und ihre verwendung

Info

Publication number: ATE219103T1
Authority: AT; Austria
Prior art keywords: ser; arg; gly; phe; leu
Prior art date: 1991-01-31

Application number

AT92101621T

Other languages

English (en)

Inventor

Shoji Tanaka

Yoshiharu Minamitake

Yasuo Kitajima

Mayumi Furuya

Hisayuki Matsuo

Original Assignee

Suntory Ltd

Hisayuki Matsuo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-01-31

Filing date

1992-01-31

Publication date

2002-06-15

1992-01-31 Application filed by Suntory Ltd, Hisayuki Matsuo filed Critical Suntory Ltd

2002-06-15 Application granted granted Critical

2002-06-15 Publication of ATE219103T1 publication Critical patent/ATE219103T1/de

Links

102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 abstract 2
DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
101800000060 C-type natriuretic peptide Proteins 0.000 abstract 1
102400001025 CNP-22 Human genes 0.000 abstract 1
101800000457 CNP-22 Proteins 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
239000004615 ingredient Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
210000004509 vascular smooth muscle cell Anatomy 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Toxicology (AREA)
Genetics & Genomics (AREA)
Endocrinology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Cardiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT92101621T 1991-01-31 1992-01-31 Cnp-analoge peptide und ihre verwendung ATE219103T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP1132191		1991-01-31
JP3254066A JP2809533B2 (ja)	1991-01-31	1991-06-28	Ｃｎｐ類似体ペプチド

Publications (1)

Publication Number	Publication Date
ATE219103T1 true ATE219103T1 (de)	2002-06-15

Family

ID=26346733

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92101621T ATE219103T1 (de)	1991-01-31	1992-01-31	Cnp-analoge peptide und ihre verwendung

Country Status (6)

Country	Link
US (1)	US5434133A (de)
EP (1)	EP0497368B1 (de)
JP (1)	JP2809533B2 (de)
AT (1)	ATE219103T1 (de)
DE (1)	DE69232636T2 (de)
ES (1)	ES2178634T3 (de)

Families Citing this family (55)

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AU6360394A (en) *	1993-03-03	1994-09-26	Mayo Foundation For Medical Education And Research	Vasonatrin peptide and analogs thereof
US5665704A (en) *	1993-11-12	1997-09-09	Genentech, Inc.	Receptor specific atrial natriuretic peptides
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CA2345414A1 (en) *	1998-09-28	2000-04-06	Santen Pharmaceutical Co., Ltd.	Eyedrops for promoting lacrimal secretion or treating keratoconjunctival disorders containing natriuretic peptide as active ingredient
DE19903087A1 (de) *	1999-01-27	2000-08-10	Forssmann Wolf Georg	Behandlung von erektilen Dysfunktionen mit C-Typ Natriuretischem Polypeptid (CNP) als Monotherapie oder in Kombination mit Phosphodiesterasehemmern
IL142118A0 (en) *	2001-03-20	2002-03-10	Prochon Biotech Ltd	Method and composition for treatment of skeletal dysplasias
BRPI0203172B8 (pt)	2001-09-28	2021-05-25	Nakao Kazuwa	composição farmacêutica para acondroplasia
EP1610808A4 (de) *	2003-03-26	2011-04-06	Sudhir Paul	Kovalente bindung von liganden an nucleophile proteine unter führung durch nichtkovalente bindung
DE602004029680D1 (de)	2003-06-20	2010-12-02	Mayo Foundation	Isoformen von gehirn-natriuretischem peptid
EP3620530A1 (de)	2004-03-31	2020-03-11	Kazuwa Nakao	Zusammensetzung zur erhöhung der körpergrösse
JP4825667B2 (ja)	2004-03-31	2011-11-30	一和中尾	関節炎症治療剤又は予防剤
HUE055861T2 (hu)	2004-04-21	2021-12-28	Alexion Pharma Inc	Csontbejuttató konjugátumok és azok alkalmazási módszere fehérjék csonthoz kötéséhez
KR101434612B1 (ko)	2006-03-30	2014-08-26	팔라틴 테크놀로지스 인코포레이티드	사이클릭 나트륨 이뇨 펩타이드 구조물
US7795221B2 (en)	2006-03-30	2010-09-14	Palatin Technologies, Inc.	Linear natriuretic peptide constructs
US8580746B2 (en)	2006-03-30	2013-11-12	Palatin Technologies, Inc.	Amide linkage cyclic natriuretic peptide constructs
EP2054433B1 (de)	2006-08-08	2017-12-13	Mayo Foundation For Medical Education And Research	Diuretische und natriuretische polypeptide
AU2008279379B2 (en) *	2007-07-20	2016-03-24	Mayo Foundation For Medical Education And Research	Natriuretic polypeptides
WO2009046873A1 (en) *	2007-09-11	2009-04-16	Mondobiotech Laboratories Ag	Combined use of vasonatrin and gastrin-i as a therapeutic agent
WO2009036448A2 (en) *	2007-09-15	2009-03-19	Mayo Foundation For Medical Education And Research	Natriuretic peptide receptor-c agonists
AU2008326327A1 (en)	2007-11-21	2009-05-28	Biomarin Pharmaceutical Inc.	Variants of C-type natriuretic peptide
WO2009086126A2 (en) *	2007-12-21	2009-07-09	Mayo Foundation For Medical Education And Research	Natriuretic polypeptides
PE20120792A1 (es)	2009-05-20	2012-07-27	Biomarin Pharm Inc	Variantes de peptidos natriureticos de tipo c
US20120208756A1 (en)	2009-07-23	2012-08-16	Igisu Co., Ltd	Composition for external preparation for skin
RU2502519C2 (ru)	2009-08-27	2013-12-27	Кёко ЭНДО	Терапевтическое средство для лечения ринита
WO2012013597A1 (de) *	2010-07-28	2012-02-02	Justus-Liebig-Universität Giessen	Stoffe und deren verwendung zur beeinflussung natriuretischer peptidrezeptoren
US9266939B2 (en)	2010-12-27	2016-02-23	Alexion Pharmaceuticals, Inc.	Compositions comprising natriuretic peptides and methods of use thereof
HUE035584T2 (en)	2011-01-21	2018-05-28	Igisu Co Ltd	A therapeutic agent for the treatment of allopathy
EP2682128B1 (de) *	2011-02-28	2017-11-08	National Cerebral and Cardiovascular Center	Atriales natriuretisches peptid oder natriuretisches peptide typ b zur verhinderung der metastase
KR20140059249A (ko)	2011-08-30	2014-05-15	메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치	나트륨이뇨 폴리펩티드
SG11201401605QA (en)	2011-10-19	2014-09-26	Alexion Pharma Holding	Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof
WO2013103896A1 (en)	2012-01-06	2013-07-11	Mayo Foundation For Medical Education And Research	Treating cardiovascular or renal diseases
US10052366B2 (en)	2012-05-21	2018-08-21	Alexion Pharmaceuticsl, Inc.	Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof
CN104059154B (zh) *	2014-05-06	2017-09-29	中国人民解放军第四军医大学	一种新的具有抗心力衰竭作用的钠尿肽嵌合体cnaac
WO2016007873A1 (en)	2014-07-11	2016-01-14	The Regents Of The University Of Michigan	Compositions and methods for treating craniosynostosis
CA2967851C (en)	2014-12-05	2024-02-27	Alexion Pharmaceuticals, Inc.	Treating seizure with recombinant alkaline phosphatase
AU2016211447B2 (en)	2015-01-28	2021-09-23	Alexion Pharmaceuticals, Inc.	Methods of treating a subject with an alkaline phosphatase deficiency
CN114796460A (zh)	2015-07-30	2022-07-29	生物马林药物股份有限公司	C型利尿钠肽变体在治疗骨骼发育不良中的用途
JP7253220B2 (ja) *	2015-07-31	2023-04-06	株式会社イギス	Ｃｎｐ環状ペプチド並びに該環状ペプチドを含む医薬品、外用剤および化粧料
EP3337894A1 (de)	2015-08-17	2018-06-27	Alexion Pharmaceuticals, Inc.	Herstellung von alkalischen phosphatasen
JP6868617B2 (ja)	2015-09-28	2021-05-12	アレクシオンファーマシューティカルズ，インコーポレイテッド	低ホスファターゼ血症の組織非特異的アルカリホスファターゼ（ｔｎｓａｌｐ）酵素補充療法に有効な投薬計画の特定
US11400140B2 (en)	2015-10-30	2022-08-02	Alexion Pharmaceuticals, Inc.	Methods for treating craniosynostosis in a patient
CA3007315A1 (en)	2015-12-08	2017-06-15	Biomarin Pharmaceutical Inc.	Use of c-type natriuretic peptide variants to treat osteoarthritis
US11065306B2 (en)	2016-03-08	2021-07-20	Alexion Pharmaceuticals, Inc.	Methods for treating hypophosphatasia in children
WO2017173395A1 (en)	2016-04-01	2017-10-05	Alexion Pharmaceuticals, Inc.	Methods for treating hypophosphatasia in adolescents and adults
KR20220162816A (ko)	2016-04-01	2022-12-08	알렉시온 파마슈티칼스, 인코포레이티드	알칼리성 포스파타아제로 근육 약화의 치료
US10988744B2 (en)	2016-06-06	2021-04-27	Alexion Pharmaceuticals, Inc.	Method of producing alkaline phosphatase
WO2018035420A1 (en)	2016-08-18	2018-02-22	Alexion Pharmaceuticals, Inc.	Methods for treating tracheobronchomalacia
JP2020512363A (ja)	2017-03-31	2020-04-23	アレクシオンファーマシューティカルズ，インコーポレイテッド	成人及び青年における低ホスファターゼ症（ｈｐｐ）を治療する方法
JP2021519590A (ja)	2018-03-30	2021-08-12	アレクシオンファーマシューティカルズ，インコーポレイテッド	糖タンパク質の製造
WO2020033867A2 (en)	2018-08-10	2020-02-13	Alexion Pharmaceuticals, Inc.	Methods of treating neurofibromatosis type 1 and related conditions with alkaline phosphatase
JP7796645B2 (ja)	2019-12-09	2026-01-09	アレクシオンファーマシューティカルズ，インコーポレイテッド	アルカリホスファターゼポリペプチド及びその使用方法
CA3173631A1 (en)	2021-02-12	2022-08-18	Walter C. Voegtli	Alkaline phosphatase polypeptides and methods of use thereof
KR20250088609A (ko)	2022-10-21	2025-06-17	일라이 릴리 앤드 캄파니	장기-작용 나트륨이뇨 펩티드 및 그의 용도
KR102866559B1 (ko)	2022-11-02	2025-10-02	노보 노르디스크 에이/에스	Cnp 화합물

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US4496544A (en) *	1983-11-10	1985-01-29	Washington University	Atrial Peptides
JPH0672157B2 (ja) *	1984-08-29	1994-09-14	味の素株式会社	新規ペプチド
EP0232078A3 (de) *	1986-01-31	1990-03-14	Merck & Co. Inc.	Peptide mit ANF-Wirkung
EP0292256A3 (de) *	1987-05-19	1990-10-03	Merck & Co. Inc.	Peptide mit ANF-Wirksamkeit
US4935492A (en) *	1987-12-24	1990-06-19	California Biotechnology Inc.	Cyclic analogs of atrial natriuretic peptides
CA1339210C (en) *	1988-05-31	1997-08-05	John Lewicki	Recombinant techniques for production of novel natriuretic and vasodilator peptides
DK380288D0 (da) *	1988-07-07	1988-07-07	Novo Industri As	Hidtil ukendet peptider
DE69108830T2 (de) *	1990-04-20	1995-09-14	Hisayuki Matsuo	Neue im schwein vorkommende physiologisch aktive peptide.
JP2801079B2 (ja) *	1990-11-14	1998-09-21	サントリー株式会社	Ａｎｐ関連新規ペプチド

1991
- 1991-06-28 JP JP3254066A patent/JP2809533B2/ja not_active Expired - Lifetime
1992
- 1992-01-31 US US07/828,450 patent/US5434133A/en not_active Expired - Lifetime
- 1992-01-31 EP EP92101621A patent/EP0497368B1/de not_active Expired - Lifetime
- 1992-01-31 AT AT92101621T patent/ATE219103T1/de not_active IP Right Cessation
- 1992-01-31 DE DE69232636T patent/DE69232636T2/de not_active Expired - Lifetime
- 1992-01-31 ES ES92101621T patent/ES2178634T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0497368B1 (de)	2002-06-12
US5434133A (en)	1995-07-18
JPH069688A (ja)	1994-01-18
DE69232636D1 (de)	2002-07-18
EP0497368A1 (de)	1992-08-05
ES2178634T3 (es)	2003-01-01
DE69232636T2 (de)	2002-12-05
JP2809533B2 (ja)	1998-10-08

Legal Events

Date	Code	Title	Description
2002-12-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE219103T1 (de)	2002-06-15	Cnp-analoge peptide und ihre verwendung
DE59007517D1 (de)	1994-11-24	Neue proteine mit tnf-hemmender wirkung und ihre herstellung.
ATE386118T1 (de)	2008-03-15	Cnp-gen und vorläuferprotein aus schwein
CA2121724A1 (en)	1994-10-22	Methods and compositions for the prophylactic and/or therapeutic treatment of organ hypofunction
UA35636C2 (uk)	2001-04-16	Поліпептид, який має активність легеневої поверхнево-активної речовини, та фармацевтична композиція для лікування респіраторного дистрес-синдрому у ссавців
WO1998021237A3 (en)	1998-07-30	Peptide compounds useful for modulating FGF receptor activity
SE9100799D0 (sv)	1991-03-15	Recombinant human factor viii derivatives
EP0378641A4 (en)	1990-12-12	Novel antimicrobial peptide, compositions containing same and uses thereof
ES2054365T3 (es)	1994-08-01	Inhibicion de la via de la regla del n final en celulas vivas.
DE69126487D1 (de)	1997-07-17	cDNA für Ratten C-Typ natriuretisches Peptid und Vorläuferprotein
IS2819B (is)	2012-12-15	Viðloðunarsameindir í æðum og mótun á starfsemi@þeirra
DK302388D0 (da)	1988-06-03	Proteiner
TW224975B (de)	1994-06-11
EP0310887A3 (en)	1990-07-18	Vasoconstrictor peptide
AU682638B2 (en)	1997-10-09	Peptide, bronchodilator and blood flow ameliorant
EP0292257A3 (de)	1990-06-06	Peptide mit ANF-Wirksamkeit
EP0330700A4 (de)	1990-01-08	Menschlicher Prourokinase ähnliches Polypeptid.
GB1294771A (en)	1972-11-01	Thyrocalcitonin derivative
DE3751398D1 (de)	1995-08-17	Substrat-Peptide.
EP0687685A4 (de)	1998-07-01	Physiologisch-aktive peptide
JPS6426598A (en)	1989-01-27	Calcitonin gene related peptide derivative
KR950011466A (ko)	1995-05-15	선형 결합 억제제
ATE152733T1 (de)	1997-05-15	Bradykinin-antagonisten zur behandlung von akuter pankreatitis
DE453719T1 (de)	1992-04-30	Bakteriozin-peptid.
AU633128B2 (en)	1993-01-21	Anticoagulant peptides