ATE220666T1 - 4-diphenylmethylpiperidine und verfahren zu ihrer herstellung - Google Patents

4-diphenylmethylpiperidine und verfahren zu ihrer herstellung

Info

Publication number
ATE220666T1
ATE220666T1 AT93907333T AT93907333T ATE220666T1 AT E220666 T1 ATE220666 T1 AT E220666T1 AT 93907333 T AT93907333 T AT 93907333T AT 93907333 T AT93907333 T AT 93907333T AT E220666 T1 ATE220666 T1 AT E220666T1
Authority
AT
Austria
Prior art keywords
diphenylmethylpiperidine
production
Prior art date
Application number
AT93907333T
Other languages
English (en)
Inventor
Chi-Hsin Richard King
Michele A Kaminski
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Application granted granted Critical
Publication of ATE220666T1 publication Critical patent/ATE220666T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT93907333T 1992-04-10 1993-03-10 4-diphenylmethylpiperidine und verfahren zu ihrer herstellung ATE220666T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86726192A 1992-04-10 1992-04-10
US1725193A 1993-02-25 1993-02-25
PCT/US1993/002103 WO1993021156A1 (en) 1992-04-10 1993-03-10 4-diphenylmethyl piperidine derivatives and process for their preparation

Publications (1)

Publication Number Publication Date
ATE220666T1 true ATE220666T1 (de) 2002-08-15

Family

ID=26689638

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93907333T ATE220666T1 (de) 1992-04-10 1993-03-10 4-diphenylmethylpiperidine und verfahren zu ihrer herstellung

Country Status (19)

Country Link
EP (1) EP0635004B1 (de)
JP (3) JP3686950B2 (de)
KR (1) KR100257805B1 (de)
AR (1) AR253777A1 (de)
AT (1) ATE220666T1 (de)
AU (1) AU671822B2 (de)
CA (1) CA2117892C (de)
DE (1) DE69332117T2 (de)
DK (1) DK0635004T3 (de)
ES (1) ES2176201T3 (de)
FI (2) FI106454B (de)
HU (1) HU226561B1 (de)
IL (1) IL105328A (de)
MX (1) MX9302076A (de)
NO (5) NO305076B1 (de)
NZ (1) NZ251132A (de)
PT (1) PT635004E (de)
TW (1) TW362096B (de)
WO (1) WO1993021156A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2167657C2 (ru) * 1992-08-03 2001-05-27 Сепракор, Инк. Фармацевтическая композиция для лечения аллергических заболеваний, способ антигистаминного лечения, применение композиции для получения лекарственного препарата
DK1026147T3 (da) 1993-06-24 2004-03-22 Albany Molecular Res Inc Forbindelser, der er anvendelige som mellemprodukter i fremstillingen af piperidinderivater
US20020007068A1 (en) 1999-07-16 2002-01-17 D'ambra Thomas E. Piperidine derivatives and process for their production
US6147216A (en) * 1993-06-25 2000-11-14 Merrell Pharmaceuticals Inc. Intermediates useful for the preparation of antihistaminic piperidine derivatives
CA2362337C (en) 1993-06-25 2005-08-02 Merrell Pharmaceuticals Inc. Novel intermediates for the preparation of antihistaminic 4-diphenylmethyl/diphenylmethoxy piperidine derivatives
CN1623985A (zh) 1994-05-18 2005-06-08 阿温蒂斯药物公司 抗组胺哌啶衍生物，其多晶形物和假同晶物的无水和水合物形式的制备方法
DE69624559T2 (de) 1995-02-28 2003-07-10 Aventis Pharmaceuticals Inc., Bridgewater Arzneizubereitungen für piperidinalkanolderivate
US6153754A (en) 1995-12-21 2000-11-28 Albany Molecular Research, Inc. Process for production of piperidine derivatives
US6201124B1 (en) 1995-12-21 2001-03-13 Albany Molecular Research, Inc. Process for production of piperidine derivatives
CN1246312C (zh) * 1998-07-02 2006-03-22 阿旺蒂斯制药公司 新的抗组胺哌啶衍生物及制备其的中间体
MXPA03009259A (es) * 2001-04-09 2004-06-03 Teva Pharma Polimorfos de clorhidrato de fexofenadina.
ITRM20010260A1 (it) 2001-05-17 2002-11-18 Dinamite Dipharma S P A In For Processo per la preparazione della fexofenadina o acido 4 1-idrossi-4-4- (idrossidifenilmetil)-1-piperidinil|-butil|-alfa,alfa-dimetilbenz
US6743941B2 (en) * 2001-06-15 2004-06-01 Aventis Pharma Deutschland Gmbh Process for the production of piperidine derivatives
WO2003104197A1 (en) 2002-06-10 2003-12-18 Teva Pharmaceutical Industries Ltd. Polymorphic form xvi of fexofenadine hydrochloride
GB0319935D0 (en) 2003-08-26 2003-09-24 Cipla Ltd Polymorphs
ITMI20061492A1 (it) * 2006-07-27 2008-01-28 Archimica Srl Processo per la preparazione di fexofenadina.
ITMI20070987A1 (it) 2007-05-16 2008-11-17 Dipharma Francis Srl Procedimento per la preparazione di composti chetonici
EP2289867A3 (de) 2009-08-19 2012-04-25 Jubilant Organosys Limited Verfahren zur Herstellung von 4-(4-Halogen-1-oxybutyl)-alpha,alpha-dimethylbenzolessigsäure oder Alkylestern davon

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4254129A (en) * 1979-04-10 1981-03-03 Richardson-Merrell Inc. Piperidine derivatives
US4254130A (en) * 1979-04-10 1981-03-03 Richardson-Merrell Inc. Piperidine derivatives

Also Published As

Publication number Publication date
FI20002460A7 (fi) 2000-11-09
IL105328A (en) 2007-03-08
NO943794D0 (no) 1994-10-07
HUT70517A (en) 1995-10-30
NO305024B1 (no) 1999-03-22
AR253777A1 (es) 2001-10-08
JP2004285072A (ja) 2004-10-14
PT635004E (pt) 2002-12-31
HU9402913D0 (en) 1995-01-30
FI944713A0 (fi) 1994-10-07
NO981433D0 (no) 1998-03-30
IL105328A0 (en) 1993-08-18
WO1993021156A1 (en) 1993-10-28
CA2117892C (en) 2001-12-18
DE69332117D1 (de) 2002-08-22
DE69332117T2 (de) 2003-01-30
FI20002460L (fi) 2000-11-09
NO981434D0 (no) 1998-03-30
NO305023B1 (no) 1999-03-22
EP0635004B1 (de) 2002-07-17
NO943794L (no) 1994-12-09
NO981431D0 (no) 1998-03-30
NZ251132A (en) 1996-12-20
NO305077B1 (no) 1999-03-29
DK0635004T3 (da) 2002-11-11
KR100257805B1 (ko) 2000-07-01
JP4266184B2 (ja) 2009-05-20
ES2176201T3 (es) 2002-12-01
MX9302076A (es) 1994-03-31
NO981433L (no) 1994-12-09
NO305025B1 (no) 1999-03-22
HU226561B1 (en) 2009-04-28
NO981431L (no) 1994-12-09
AU671822B2 (en) 1996-09-12
KR950700881A (ko) 1995-02-20
NO981432D0 (no) 1998-03-30
JPH08502022A (ja) 1996-03-05
JP2005213268A (ja) 2005-08-11
NO981432L (no) 1994-12-09
CA2117892A1 (en) 1993-10-28
AU3797393A (en) 1993-11-18
NO305076B1 (no) 1999-03-29
FI106454B (fi) 2001-02-15
TW362096B (en) 1999-06-21
FI944713L (fi) 1994-12-02
EP0635004A1 (de) 1995-01-25
NO981434L (no) 1994-12-09
JP3686950B2 (ja) 2005-08-24

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