ATE221905T1 - Struktuierte copolymere als metallionenträger - Google Patents

Struktuierte copolymere als metallionenträger

Info

Publication number
ATE221905T1
ATE221905T1 AT94909483T AT94909483T ATE221905T1 AT E221905 T1 ATE221905 T1 AT E221905T1 AT 94909483 T AT94909483 T AT 94909483T AT 94909483 T AT94909483 T AT 94909483T AT E221905 T1 ATE221905 T1 AT E221905T1
Authority
AT
Austria
Prior art keywords
modified
dendrimers
metal ion
capping
hydrophobic
Prior art date
Application number
AT94909483T
Other languages
English (en)
Inventor
David M Hedstrand
Donald A Tomalia
Bradley J Helmer
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Application granted granted Critical
Publication of ATE221905T1 publication Critical patent/ATE221905T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002—Dendritic macromolecules
    • C08G83/003—Dendrimers
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • A01N25/10—Macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/595—Polyamides, e.g. nylon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/29—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/11—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/26—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
    • C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/0206—Polyalkylene(poly)amines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/024—Polyamines containing oxygen in the form of ether bonds in the main chain
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/028—Polyamidoamines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L101/00—Compositions of unspecified macromolecular compounds
    • C08L101/005—Dendritic macromolecules
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L79/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing nitrogen with or without oxygen or carbon only, not provided for in groups C08L61/00 - C08L77/00
    • C08L79/02—Polyamines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L25/00—Compositions of, homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring; Compositions of derivatives of such polymers
    • C08L25/02—Homopolymers or copolymers of hydrocarbons
    • C08L25/04—Homopolymers or copolymers of styrene
    • C08L25/06—Polystyrene

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Medical Informatics (AREA)
  • Environmental Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
AT94909483T 1993-01-22 1994-01-21 Struktuierte copolymere als metallionenträger ATE221905T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US827593A 1993-01-22 1993-01-22
US08/152,335 US5560929A (en) 1986-08-18 1993-11-12 Structured copolymers and their use as absorbents, gels and carriers of metal ions
PCT/US1994/000801 WO1994017125A1 (en) 1993-01-22 1994-01-21 Structured copolymers used as absorbents, gels and carriers of metal ions

Publications (1)

Publication Number Publication Date
ATE221905T1 true ATE221905T1 (de) 2002-08-15

Family

ID=26678019

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94909483T ATE221905T1 (de) 1993-01-22 1994-01-21 Struktuierte copolymere als metallionenträger

Country Status (14)

Country Link
US (1) US5560929A (de)
EP (1) EP0680495B1 (de)
JP (1) JPH08505899A (de)
KR (1) KR100295923B1 (de)
CN (2) CN1038842C (de)
AT (1) ATE221905T1 (de)
AU (1) AU683875B2 (de)
CA (1) CA2154469C (de)
CZ (1) CZ291389B6 (de)
DE (1) DE69431150T2 (de)
FI (1) FI109910B (de)
HU (1) HU220996B1 (de)
TW (1) TW337531B (de)
WO (1) WO1994017125A1 (de)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3938992A1 (de) * 1989-11-21 1991-05-23 Schering Ag Kaskadenpolymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
US5795587A (en) 1995-01-23 1998-08-18 University Of Pittsburgh Stable lipid-comprising drug delivery complexes and methods for their production
US6051429A (en) 1995-06-07 2000-04-18 Life Technologies, Inc. Peptide-enhanced cationic lipid transfections
US20030069173A1 (en) * 1998-03-16 2003-04-10 Life Technologies, Inc. Peptide-enhanced transfections
US5658574A (en) * 1995-10-13 1997-08-19 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Cleansing compositions with dendrimers as mildness agents
NL1001753C2 (nl) * 1995-11-28 1997-05-30 Dsm Nv Samenstelling omvattende een kunststof en een additief.
CA2274458A1 (en) * 1997-01-13 1998-07-16 Dendritech, Inc. Nanocomposites of dendritic polymers
US5739218A (en) * 1997-06-02 1998-04-14 Dow Corning Corporation Radially layered copoly (amidoamine-organosilicon) dendrimers
WO1998056427A1 (en) * 1997-06-12 1998-12-17 Mitsubishi Chemical Corporation Novel contrast media
WO1998058970A1 (en) * 1997-06-25 1998-12-30 Exxon Chemical Patents Inc. Star-branched polymer with dendrimer core
US6545101B2 (en) 1997-06-25 2003-04-08 Exxonmobil Chemical Patents Inc. Star-branched polymer with dendrimer core
US6228978B1 (en) 1997-06-25 2001-05-08 Exxon Mobil Chemical Patents Inc Star-branched polymer with dendrimer core
US5902863A (en) * 1997-07-21 1999-05-11 Dow Corning Corporation Dendrimer-based networks containing lyophilic organosilicon and hydrophilic polyamidoamine nanoscopic domains
US6056805A (en) * 1997-08-15 2000-05-02 Guardian Environmental Technologies, Inc. Method and apparatus for the absorption of non-polar organic molecules on hydrocarbon block copolymers
US6252014B1 (en) 1998-08-04 2001-06-26 Colorado School Of Mines Star polymers and polymeric particles in the nanometer-sized range by step growth reactions
NZ512244A (en) 1998-11-12 2003-12-19 Invitrogen Corp Polycationic transfection reagents for introducing anions into a cell
US6258896B1 (en) * 1998-12-18 2001-07-10 3M Innovative Properties Company Dendritic polymer dispersants for hydrophobic particles in water-based systems
FR2790642A1 (fr) * 1999-03-08 2000-09-15 Aventis Cropscience Sa Nouvelles compositions pesticides et/ou regulatrices de croissance
US6077500A (en) * 1999-03-18 2000-06-20 Dow Corning Corporation High generation radially layered dendrimers
US6858229B1 (en) 1999-04-26 2005-02-22 California Institute Of Technology In situ forming hydrogels
AU4977800A (en) * 1999-04-26 2000-11-10 California Institute Of Technology (in situ) forming hydrogels
FR2797563A1 (fr) * 1999-08-18 2001-02-23 Rhodianyl Composes biocides et leur utilisation dans des polymeres thermoplastiques
JP3181276B2 (ja) 1999-08-31 2001-07-03 科学技術振興事業団 樹枝状分岐構造を持つ両親媒性化合物
US20040146918A1 (en) * 2000-02-18 2004-07-29 Weiner Michael L. Hybrid nucleic acid assembly
US6471968B1 (en) 2000-05-12 2002-10-29 Regents Of The University Of Michigan Multifunctional nanodevice platform
US6350384B1 (en) 2000-08-14 2002-02-26 Dow Corning Corporation Silicon containing multi-arm star polymers
FR2814164B1 (fr) * 2000-09-18 2002-11-22 Rhodia Chimie Sa Materiau cimentaire comprenant un polymere dendritique
US6350819B1 (en) 2000-10-27 2002-02-26 Union Carbide Chemicals & Plastics Technology Corporation Dendritic macromolecules for metal-ligand catalyzed processes
KR100413532B1 (ko) * 2001-02-14 2003-12-31 학교법인 포항공과대학교 폴리아민이 말단에 치환된 덴드리머 및 그 제조방법
US6673205B2 (en) * 2001-05-10 2004-01-06 Fort James Corporation Use of hydrophobically modified polyaminamides with polyethylene glycol esters in paper products
AU2002350991A1 (en) * 2001-06-25 2003-01-08 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Macromolecular imaging agents for liver imaging
JP3984541B2 (ja) * 2001-12-26 2007-10-03 財団法人川村理化学研究所 星型ポリオキサゾリンからなる粒子およびその製造方法
GB0209022D0 (en) * 2002-04-19 2002-05-29 Imp College Innovations Ltd Compounds
US7412121B2 (en) * 2002-10-24 2008-08-12 Applied Research And Photonics, Inc. Nanophotonic integrated circuit and fabrication thereof
US7001580B2 (en) * 2002-12-31 2006-02-21 3M Innovative Properties Company Emulsions including surface-modified organic molecules
JP2007524844A (ja) * 2003-09-22 2007-08-30 ベクトン・ディキンソン・アンド・カンパニー デンドリマー内部標準を使用する質量分析による生体分子検体の定量化
WO2005061014A1 (de) * 2003-12-19 2005-07-07 Basf Aktiengesellschaft Quellbare hydrogelbildende polymere mit geringem feinstaubanteil
US20050171424A1 (en) * 2004-01-13 2005-08-04 The Gov. Of The Usa As Rep. By The Secretary Of The Dept. Of Health And Human Services Methods for imaging the lymphatic system using dendrimer-based contrast agents
DE102004015686A1 (de) * 2004-03-29 2005-10-27 Basf Ag Quellbare hydrogelbildende Polymere mit hoher Permeabilität
ATE432723T1 (de) * 2004-03-29 2009-06-15 Procter & Gamble Absorbierendes element für absorbierende artikel enthaltend hydrogel-formende, quellbare polymere mit hoher permeabilität
US8911942B2 (en) * 2004-05-20 2014-12-16 Quest Diagnostics Investments Incorporated Single label comparative hybridization
US7323109B2 (en) * 2004-06-15 2008-01-29 Eastman Kodak Company Composition comprising metal-ion sequestrant
US20050276862A1 (en) * 2004-06-15 2005-12-15 Bringley Joseph F Iron sequestering antimicrobial composition
US7723285B2 (en) * 2004-07-20 2010-05-25 Michigan Molecular Institute Beneficial agent delivery systems
MX265137B (es) 2004-08-17 2009-03-13 Unilever Nv Composiciones para el cuidado del cabello que comprenden un polimero dendritico.
ES2360639T5 (es) * 2004-08-17 2014-02-26 Unilever N.V. Procedimiento de tratamiento del cabello con una composición que comprende una macromolécula dendrítica
JP2008510829A (ja) * 2004-08-25 2008-04-10 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン デンドリマーに基づく組成物およびそれらの使用法
US20070041934A1 (en) * 2005-08-12 2007-02-22 Regents Of The University Of Michigan Dendrimer based compositions and methods of using the same
US8076074B2 (en) 2005-11-29 2011-12-13 Quest Diagnostics Investments Incorporated Balanced translocation in comparative hybridization
US8492098B2 (en) 2006-02-21 2013-07-23 The Trustees Of Tufts College Methods and arrays for target analyte detection and determination of reaction components that affect a reaction
US7914588B2 (en) * 2007-04-10 2011-03-29 Los Alamos National Security, Llc Synthesis of fluorescent metal nanoclusters
US20090088376A1 (en) * 2007-04-19 2009-04-02 The Regents Of The University Of Michigan Dendrimer based compositions and methods of using the same
JP5446119B2 (ja) * 2007-05-08 2014-03-19 公立大学法人大阪府立大学 低級アシル基含有ポリアミドアミンデンドロン脂質
US7507539B2 (en) * 2007-07-30 2009-03-24 Quest Diagnostics Investments Incorporated Substractive single label comparative hybridization
WO2009151687A2 (en) 2008-03-12 2009-12-17 The Regents Of The University Of Michigan Dendrimer conjugates
WO2010039861A2 (en) 2008-09-30 2010-04-08 The Regents Of The University Of Michigan Dendrimer conjugates
US9017644B2 (en) 2008-11-07 2015-04-28 The Regents Of The University Of Michigan Methods of treating autoimmune disorders and/or inflammatory disorders
WO2011059609A2 (en) 2009-10-13 2011-05-19 The Regents Of The University Of Michigan Dendrimer compositions and methods of synthesis
WO2011059586A2 (en) 2009-10-30 2011-05-19 The Regents Of The University Of Michigan Multifunctional small molecules
EP2778221B1 (de) 2011-02-07 2017-07-26 Life Technologies Corporation Zusammensetzungen und Verfahren zur Stabilisierung von empfindlichen Verbindungen
WO2013085718A1 (en) 2011-12-08 2013-06-13 The Regents Of The University Of Michigan Multifunctional small molecules
ES2580334T3 (es) 2014-01-13 2016-08-23 Yang, Guanghua Composiciones de dendrímeros, métodos de síntesis, y sus usos
EP3169310A1 (de) 2014-07-15 2017-05-24 Life Technologies Corporation Zusammensetzungen mit lipidaggregaten und verfahren zur effizienten bereitstellung von molekülen an zellen
CN110799492B (zh) * 2017-04-28 2023-06-27 爱康泰生治疗公司 用于递送核酸的新型羰基脂质和脂质纳米颗粒制剂
WO2019040340A1 (en) 2017-08-21 2019-02-28 The Hive Global, Inc. BICYCLE CASSETTE COMPRISING A CLAMP CONNECTION
CN108840807B (zh) * 2018-08-23 2019-07-05 东北石油大学 蓝紫色荧光体及其制备方法
CN109433718A (zh) * 2018-10-25 2019-03-08 湖北金洋资源股份公司 一种含油污金属件清洗工艺
US20240218155A1 (en) * 2022-12-28 2024-07-04 Zju-hangzhou Global Scientific And Technological Innovation Center Antistatic composition and olefin polymerization method

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US469064A (en) * 1892-02-16 Tooth-pick case
US3200106A (en) * 1960-08-04 1965-08-10 Petrolite Corp Derivatives of branched polyalkylene-polyamines
US3514250A (en) * 1965-03-25 1970-05-26 Petrolite Corp Process of inhibiting corrosion
US3445441A (en) * 1965-03-25 1969-05-20 Petrolite Corp Amino-amido polymers
US3580891A (en) * 1968-04-16 1971-05-25 Seekay Chemical Co Water-insoluble,cross-linked polymeric reaction product of ethylene diamine and nitrilotriacetic acid or derivative
US3528928A (en) * 1969-01-13 1970-09-15 Petrolite Corp Process of breaking oil-in-water emulsions
US3578643A (en) * 1969-06-06 1971-05-11 Grace W R & Co New polymers from nitrilotriacetonitrile and iminodiacetonitrile
BE756896A (fr) * 1969-10-01 1971-03-30 Montedison Spa Polyamides basiques, leurs procedes de preparation et leurs applications
US4036808A (en) * 1972-08-14 1977-07-19 California Institute Of Technology Conductive hydrogel containing 3-ionene
US4102827A (en) * 1973-12-26 1978-07-25 California Institute Of Technology Novel polyelectrolytes
US4315087A (en) * 1975-04-28 1982-02-09 Petrolite Corporation Quaternary polyaminoamides
US4141847A (en) * 1977-05-11 1979-02-27 Shell Oil Company Star-shaped polymer reacted with dicarboxylic acid and amine as dispersant viscosity index improver
US4360646A (en) * 1979-04-06 1982-11-23 Allied Corporation Preparation of lysine based macromolecular highly branched homogeneous compound
US4289872A (en) * 1979-04-06 1981-09-15 Allied Corporation Macromolecular highly branched homogeneous compound based on lysine units
US4435548A (en) * 1981-04-27 1984-03-06 The Dow Chemical Company Branched polyamidoamines
US4410688A (en) * 1981-04-29 1983-10-18 Allied Corporation Macromolecular highly branched homogeneous compound
US4957939A (en) * 1981-07-24 1990-09-18 Schering Aktiengesellschaft Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging
US4472509A (en) * 1982-06-07 1984-09-18 Gansow Otto A Metal chelate conjugated monoclonal antibodies
US4631337A (en) * 1983-01-07 1986-12-23 The Dow Chemical Company Hydrolytically-stable dense star polyamine
US4558120A (en) * 1983-01-07 1985-12-10 The Dow Chemical Company Dense star polymer
US4568737A (en) * 1983-01-07 1986-02-04 The Dow Chemical Company Dense star polymers and dendrimers
US4737550A (en) * 1983-01-07 1988-04-12 The Dow Chemical Company Bridged dense star polymers
US4507466A (en) * 1983-01-07 1985-03-26 The Dow Chemical Corporation Dense star polymers having core, core branches, terminal groups
US4946824A (en) * 1983-02-22 1990-08-07 Union Carbide Chemicals And Plastics Company Inc. Connected branch copolymers, methods for their production, and copying materials including same
US4855403A (en) * 1983-02-22 1989-08-08 Union Carbide Corporation Connected branch copolymers, methods for their production, and copying materials including same
US4634586A (en) * 1984-05-21 1987-01-06 The Board Of Trustees Of The Leland Stanford Junior University Reagent and method for radioimaging leukocytes
US4606907A (en) * 1984-07-02 1986-08-19 The Dow Chemical Company Bone seeking Tc-99m complexes of phosphonate derivatives of polyamidoamines
US4857218A (en) * 1984-08-17 1989-08-15 Union Carbide Corporation Lubrication method and compositions for use therein
US4587329A (en) * 1984-08-17 1986-05-06 The Dow Chemical Company Dense star polymers having two dimensional molecular diameter
US4980148A (en) * 1985-02-06 1990-12-25 Mallinckrodt, Inc. Methods for enhancing magnetic resonance imaging
US4675173A (en) * 1985-05-08 1987-06-23 Molecular Biosystems, Inc. Method of magnetic resonance imaging of the liver and spleen
US4824659A (en) * 1985-06-07 1989-04-25 Immunomedics, Inc. Antibody conjugates
US4871779A (en) * 1985-12-23 1989-10-03 The Dow Chemical Company Ion exchange/chelation resins containing dense star polymers having ion exchange or chelate capabilities
IT1213029B (it) * 1986-01-30 1989-12-07 Bracco Ind Chimica Spa Chelati di ioni metallici paramagnetici.
US4694064A (en) * 1986-02-28 1987-09-15 The Dow Chemical Company Rod-shaped dendrimer
US4713975A (en) * 1986-05-30 1987-12-22 The Dow Chemical Company Dense star polymers for calibrating/characterizing sub-micron apertures
US5039512A (en) * 1986-08-04 1991-08-13 Salutar, Inc. NMR imaging with paramagnetic polyvalent metal salts of poly-(acid-alkylene-amino)-alkanes
EP0271180B2 (de) * 1986-08-18 1997-06-18 The Dow Chemical Company Conjugate dichter Sterne
US5175270A (en) * 1986-09-10 1992-12-29 Polyprobe, Inc. Reagents for detecting and assaying nucleic acid sequences
US4863717A (en) * 1986-11-10 1989-09-05 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon Methods for circumventing the problem of free radial reduction associated with the use of stable nitroxide free radicals as contrast agents for magnetic reasonance imaging
JPS6484336A (en) * 1987-09-26 1989-03-29 Toshiba Corp Restriction directing type inference device
US4857599A (en) * 1988-02-08 1989-08-15 The Dow Chemical Company Modified dense star polymers
US5364613A (en) * 1989-04-07 1994-11-15 Sieving Paul F Polychelants containing macrocyclic chelant moieties
CA2031197A1 (en) * 1989-04-12 1990-10-13 James P. Tam Dendritic polymer of multiple antigen peptide system useful as anti-malarial vaccine
US5041516A (en) * 1989-06-21 1991-08-20 Cornell Research Foundation, Inc. Dendritic molecules and method of production
US4938885A (en) * 1989-09-28 1990-07-03 Texaco Inc. Antioxidant dispersant polymer dendrimer
DE3938992A1 (de) * 1989-11-21 1991-05-23 Schering Ag Kaskadenpolymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
MY108621A (en) * 1990-08-01 1996-10-31 Novartis Ag Polylactide preparation and purification
US5098475A (en) * 1991-01-28 1992-03-24 Xerox Corporation Inks with dendrimer colorants
US5154853A (en) * 1991-02-19 1992-10-13 University Of South Florida Unimolecular micelles and method of making the same
US5120361A (en) * 1991-06-27 1992-06-09 Xerox Corporation Ink compositions
ATE135678T1 (de) * 1991-11-07 1996-04-15 Shell Int Research Sekundäre amine und ein verfahren zu deren herstellung
JPH06506501A (ja) * 1992-01-13 1994-07-21 デーエスエム ナムローゼ フェンノートシャップ デンドライト高分子およびその製造

Also Published As

Publication number Publication date
DE69431150D1 (de) 2002-09-12
HU220996B1 (hu) 2002-07-29
FI953530A0 (fi) 1995-07-21
CN1089775C (zh) 2002-08-28
KR960700292A (ko) 1996-01-19
HU9502024D0 (en) 1995-09-28
CN1174852A (zh) 1998-03-04
HUT73151A (en) 1996-06-28
US5560929A (en) 1996-10-01
TW337531B (en) 1998-08-01
EP0680495A1 (de) 1995-11-08
CN1038842C (zh) 1998-06-24
KR100295923B1 (ko) 2001-10-24
EP0680495B1 (de) 2002-08-07
CZ291389B6 (cs) 2003-02-12
FI953530L (fi) 1995-07-21
DE69431150T2 (de) 2003-05-22
AU683875B2 (en) 1997-11-27
CA2154469A1 (en) 1994-08-04
CN1118168A (zh) 1996-03-06
JPH08505899A (ja) 1996-06-25
FI109910B (fi) 2002-10-31
CA2154469C (en) 2004-10-05
AU6231694A (en) 1994-08-15
WO1994017125A1 (en) 1994-08-04
CZ190595A3 (en) 1995-12-13

Similar Documents

Publication Publication Date Title
ATE221905T1 (de) Struktuierte copolymere als metallionenträger
FI953531A0 (fi) Pienisoluvaahtoja ja -seoksia sekä menetelmä niiden valmistamiseksi
AU3653097A (en) Cationically charge-modified membranes
EP1116769A3 (de) Elektrolytzusammensetzung, elektrochemische Zelle und ionisches Flüssigkristallmonomer
IL136479A0 (en) Block polymer processing for mesostructured inorganic oxide materials
FR2708786B1 (fr) Micro-usinage par faisceau ionique focalisé avec auto-masquage.
GB2344214B (en) An ion implanter with improved beam definition
MY120246A (en) Method for making contact lenses having uv absorbing properties
CA2175698A1 (en) Method and apparatus for making water having purified and activated functions
CA2221813A1 (en) Substituted trifluorostyrene compositions
DE69327107D1 (de) Poröse copolymere mit polymerischer zellularstruktur, geignet für die herstellung von ionenaustauschharzen und adsorptionsmitteln
CA2171298A1 (en) Trifluorostyrene and Substituted Trifluorostyrene Copolymeric Compositions and Ion-Exchange Membranes Formed Therefrom
DK0863933T3 (da) Nye hydrogeler på basis af triblokcopolymere, deres fremstilling og deres anvendelse
WO2003036656A1 (fr) Composition electrolytique en gel de polymeres et methode de production de la composition
CA2122251A1 (en) Wettable silicone hydrogel compositions and methods for their manufacture
CA2304934A1 (en) Moisture-absorbing and desorbing polymer and compositions derived therefrom
CA2183308A1 (en) A sealing and venting component for an apparatus which generates an internal gas
IT8319365A0 (it) Composizioni miscibili con acqua abase di un polimero cationico idrofilo e di un agente tensio-attivo anionico, e utili come agenti flocculanti.
EP0564050A3 (de)
BR0210803B1 (pt) ionÈmero, método de preparação e membrana eletrolìtica polimérica compreendendo o mesmo, conjunto de eletrodo de membrana e célula combustìvel compreendendo tal conjunto.
MX169157B (es) Un electrodo de referencia de estado solido
CA2341685A1 (en) Secreted renilla luciferase
FR2763931B1 (fr) Procede de preparation d'une solution ultrapure de peroxyde d'hydrogene par echange ionique avec recyclage
AU2001296159A1 (en) A cathode layer structure for a solid polymer fuel cell and fuel cell incorporating such structure
ES2164101T3 (es) Preparacion de filamentos de poli(m-fenilenoisoftalamida).

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties