ATE222126T1 - Minocyclin und edta enthaltende beschichtungszusammensetzung für medizinische geräte - Google Patents
Minocyclin und edta enthaltende beschichtungszusammensetzung für medizinische geräteInfo
- Publication number
- ATE222126T1 ATE222126T1 AT94901405T AT94901405T ATE222126T1 AT E222126 T1 ATE222126 T1 AT E222126T1 AT 94901405 T AT94901405 T AT 94901405T AT 94901405 T AT94901405 T AT 94901405T AT E222126 T1 ATE222126 T1 AT E222126T1
- Authority
- AT
- Austria
- Prior art keywords
- edta
- glycocalyx
- minocycline
- formation
- methods
- Prior art date
Links
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 title abstract 3
- DYKFCLLONBREIL-KVUCHLLUSA-N minocycline Chemical compound C([C@H]1C2)C3=C(N(C)C)C=CC(O)=C3C(=O)C1=C(O)[C@@]1(O)[C@@H]2[C@H](N(C)C)C(O)=C(C(N)=O)C1=O DYKFCLLONBREIL-KVUCHLLUSA-N 0.000 title abstract 3
- 229960004023 minocycline Drugs 0.000 title abstract 3
- 239000008199 coating composition Substances 0.000 title 1
- 229920002306 Glycocalyx Polymers 0.000 abstract 4
- 210000004517 glycocalyx Anatomy 0.000 abstract 4
- 230000015572 biosynthetic process Effects 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 241000191963 Staphylococcus epidermidis Species 0.000 abstract 2
- 150000004676 glycans Chemical class 0.000 abstract 2
- 208000015181 infectious disease Diseases 0.000 abstract 2
- 229920001282 polysaccharide Polymers 0.000 abstract 2
- 239000005017 polysaccharide Substances 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 1
- 230000002458 infectious effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
- A61L29/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/21—Acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M2025/0056—Catheters; Hollow probes characterised by structural features provided with an antibacterial agent, e.g. by coating, residing in the polymer matrix or releasing an agent out of a reservoir
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Materials For Medical Uses (AREA)
- Paints Or Removers (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/975,486 US5362754A (en) | 1992-11-12 | 1992-11-12 | M-EDTA pharmaceutical preparations and uses thereof |
| PCT/US1993/010893 WO1994010838A1 (en) | 1992-11-12 | 1993-11-12 | M-edta pharmaceutical preparations and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE222126T1 true ATE222126T1 (de) | 2002-08-15 |
Family
ID=25523080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94901405T ATE222126T1 (de) | 1992-11-12 | 1993-11-12 | Minocyclin und edta enthaltende beschichtungszusammensetzung für medizinische geräte |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5362754A (de) |
| EP (1) | EP0668720B1 (de) |
| JP (1) | JPH08503400A (de) |
| AT (1) | ATE222126T1 (de) |
| AU (1) | AU673400B2 (de) |
| DE (1) | DE69332204T2 (de) |
| WO (1) | WO1994010838A1 (de) |
Families Citing this family (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5055455A (en) | 1988-09-28 | 1991-10-08 | Brigham And Women's Hospital | Capsular polysaccharide adhesin antigen, preparation, purification and use |
| US5688516A (en) * | 1992-11-12 | 1997-11-18 | Board Of Regents, The University Of Texas System | Non-glycopeptide antimicrobial agents in combination with an anticoagulant, an antithrombotic or a chelating agent, and their uses in, for example, the preparation of medical devices |
| US5624704A (en) * | 1995-04-24 | 1997-04-29 | Baylor College Of Medicine | Antimicrobial impregnated catheters and other medical implants and method for impregnating catheters and other medical implants with an antimicrobial agent |
| US5820607A (en) * | 1995-06-05 | 1998-10-13 | Board Of Regents, University Of Texas Systems | Multipurpose anti-microbial silastic sheath system for the prevention of device-related infections |
| US6558686B1 (en) | 1995-11-08 | 2003-05-06 | Baylor College Of Medicine | Method of coating medical devices with a combination of antiseptics and antiseptic coating therefor |
| US5756145A (en) * | 1995-11-08 | 1998-05-26 | Baylor College Of Medicine | Durable, Resilient and effective antimicrobial coating for medical devices and method of coating therefor |
| US6599714B1 (en) | 1996-03-13 | 2003-07-29 | University Technologies International Inc. | Method of growing and analyzing a biofilm |
| US20040068241A1 (en) * | 1996-06-04 | 2004-04-08 | Fischer Frank J. | Implantable medical device |
| US8304390B2 (en) * | 1997-07-31 | 2012-11-06 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method of treatment for preventing or reducing tumor growth in the liver of patient |
| US7132413B1 (en) | 1997-07-31 | 2006-11-07 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Anticoagulant/sterilizing compositions and methods |
| US20050124608A1 (en) * | 2001-04-03 | 2005-06-09 | Redmond H. P. | Treatment of cancers |
| US6165484A (en) * | 1997-08-26 | 2000-12-26 | Wake Forest University | EDTA and other chelators with or without antifungal antimicrobial agents for the prevention and treatment of fungal infections |
| US6166007A (en) | 1998-07-02 | 2000-12-26 | Sodemann; Klaus | Antimicrobial locks comprising taurinamide derivatives and carboxylic acids and/or salts thereof |
| US7252828B2 (en) | 1998-07-15 | 2007-08-07 | The Brigham And Women's Hospital, Inc. | Polysaccharide vaccine for staphylococcal infections |
| US6174537B1 (en) | 1998-09-25 | 2001-01-16 | Becton, Dickinson And Company | Catheter flush solution and method for its use |
| CA2302720C (en) * | 1999-03-29 | 2009-07-14 | Ed Geistlich Sohne Ag Fur Chemische Industrie | Anticoagulant/sterilizing compositions and methods |
| US6187768B1 (en) | 1999-06-01 | 2001-02-13 | Becton, Dickinson And Company | Kit for flushing medical devices and method of preparation |
| US7892530B2 (en) * | 1999-06-04 | 2011-02-22 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of tumor metastases and cancer |
| US7345039B2 (en) * | 1999-06-04 | 2008-03-18 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer |
| US8030301B2 (en) * | 1999-06-04 | 2011-10-04 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of cancers with methylol-containing compounds and at least one electrolyte |
| US6685694B2 (en) | 1999-07-23 | 2004-02-03 | Vasca, Inc. | Methods and kits for locking and disinfecting implanted catheters |
| US6679870B1 (en) | 1999-07-23 | 2004-01-20 | Vasca, Inc. | Methods and kits for locking and disinfecting implanted catheters |
| US6596505B2 (en) | 2000-04-17 | 2003-07-22 | University Technologies International, Inc. | Apparatus and methods for testing effects of materials and surface coatings on the formation of biofilms |
| US6599696B2 (en) | 2000-04-17 | 2003-07-29 | University Technologies International, Inc. | Effects of materials and surface coatings on encrustation and biofilm formation |
| WO2002082907A1 (en) * | 2001-01-12 | 2002-10-24 | Board Of Regents, The University Of Texas System | Novel antiseptic derivatives with broad spectrum antimicrobial activity for the impregnation of surfaces |
| EP1381372A2 (de) * | 2001-03-14 | 2004-01-21 | Paratek Pharmaceuticals, Inc. | Substituierte tetracyclin-verbindungen als synergistische antimykotische mittel |
| US6841546B2 (en) * | 2001-03-14 | 2005-01-11 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds as antifungal agents |
| EP1408987B1 (de) * | 2001-07-13 | 2013-04-10 | Paratek Pharmaceuticals, Inc. | Tetracyclin-verbindungen mit therapeutischen zielaktivitäten |
| US20030206906A1 (en) * | 2001-11-26 | 2003-11-06 | Genentech, Inc. | Catheter composition and uses thereof |
| US8541472B2 (en) * | 2001-12-05 | 2013-09-24 | Aseptica, Inc. | Antiseptic compositions, methods and systems |
| WO2003047341A2 (en) * | 2001-12-05 | 2003-06-12 | Aseptica, Inc. | Anti-microbial systems and methods |
| US6716200B2 (en) | 2002-01-18 | 2004-04-06 | C.R. Bard, Inc. | Antimicrobial urine collection system and methods of manufacturing the same |
| US8133501B2 (en) | 2002-02-08 | 2012-03-13 | Boston Scientific Scimed, Inc. | Implantable or insertable medical devices for controlled drug delivery |
| US8685427B2 (en) | 2002-07-31 | 2014-04-01 | Boston Scientific Scimed, Inc. | Controlled drug delivery |
| US6887270B2 (en) | 2002-02-08 | 2005-05-03 | Boston Scientific Scimed, Inc. | Implantable or insertable medical device resistant to microbial growth and biofilm formation |
| US7993390B2 (en) * | 2002-02-08 | 2011-08-09 | Boston Scientific Scimed, Inc. | Implantable or insertable medical device resistant to microbial growth and biofilm formation |
| US20030208166A1 (en) * | 2002-05-06 | 2003-11-06 | Schwartz Anthony H. | Implantable device with free-flowing exit and uses thereof |
| US8920826B2 (en) | 2002-07-31 | 2014-12-30 | Boston Scientific Scimed, Inc. | Medical imaging reference devices |
| WO2004043405A2 (en) | 2002-11-12 | 2004-05-27 | The Brigham And Women's Hospital, Inc. | Polysaccharide vaccine for staphylococcal infections |
| AU2003290867A1 (en) * | 2002-11-12 | 2004-06-03 | The Brigham And Women's Hospital, Inc. | Methods and products for treating staphylococcal infections |
| US7306580B2 (en) * | 2003-04-16 | 2007-12-11 | Cook Incorporated | Medical device with therapeutic agents |
| DK1644024T3 (da) | 2003-06-06 | 2019-10-07 | Univ Texas | Antimikrobielle skylleopløsninger |
| JP4916878B2 (ja) * | 2003-06-19 | 2012-04-18 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 5ht4−拮抗薬としてのアミノスルホニル置換4−(アミノメチル)−ピペリジンベンズアミド |
| AU2004296178B2 (en) * | 2003-12-04 | 2011-03-24 | The United States Of America As Represented By The Department Of Veterans Affairs | Gallium inhibits biofilm formation |
| CA2552911A1 (en) * | 2004-01-20 | 2005-08-11 | Board Of Regents, The University Of Texas System | Methods for coating and impregnating medical devices with antiseptic compositions |
| US7144992B2 (en) * | 2004-04-01 | 2006-12-05 | Kane Biotech Inc. | Synergistic antimicrobial compositions and methods for reducing biofilm formation |
| PL1745075T3 (pl) | 2004-04-21 | 2013-09-30 | Brigham & Womens Hospital Inc | Peptydy wiążące poli-N-acetyloglukozaminę (PNAG/DPNAG) i sposoby ich zastosowania |
| KR101171408B1 (ko) | 2004-05-21 | 2012-08-08 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 테트라사이클린 및 이의 유사체의 합성 |
| US7696182B2 (en) | 2004-11-02 | 2010-04-13 | Nd Partners, Llc | Antimicrobial locking solutions comprising taurinamide derivatives and biologically acceptable salts and acids, with the addition of small concentrations of heparin |
| US8906364B2 (en) | 2005-07-01 | 2014-12-09 | Kane Biotech Inc. | Antimicrobial compositions and uses thereof |
| US20080139450A1 (en) * | 2005-07-01 | 2008-06-12 | Srinivasa Madhyastha | Antimicrobial Compositions and Uses Thereof |
| JP2009511493A (ja) * | 2005-10-06 | 2009-03-19 | ノバベイ・ファーマシューティカルズ・インコーポレイテッド | N−ハロゲン化アミノ酸を使用する、尿路感染症(uti)を含む細菌感染症および真菌感染症の予防のためのシステムおよび方法 |
| WO2007062306A2 (en) | 2005-11-18 | 2007-05-31 | The Board Of Regents Of The University Of Texas System | Methods for coating surfaces with antimicrobial agents |
| MX2008010126A (es) | 2006-02-08 | 2010-02-22 | Tyrx Pharma Inc | Protesis de malla temporalmente rigidizadas. |
| US8591531B2 (en) | 2006-02-08 | 2013-11-26 | Tyrx, Inc. | Mesh pouches for implantable medical devices |
| JP5335664B2 (ja) * | 2006-04-07 | 2013-11-06 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | テトラサイクリンおよびその類似体の合成 |
| US7750201B2 (en) * | 2006-04-11 | 2010-07-06 | Tyco Healthcare Group Lp | Wound dressings with anti-microbial and chelating agents |
| US8167847B2 (en) | 2006-06-22 | 2012-05-01 | Excelsior Medical Corporation | Antiseptic cap and antiseptic cap equipped plunger and syringe barrel assembly |
| EP2479169B1 (de) | 2006-10-11 | 2014-12-03 | President and Fellows of Harvard College | Synthese eines Enon-Zwischenprodukts |
| US9023114B2 (en) | 2006-11-06 | 2015-05-05 | Tyrx, Inc. | Resorbable pouches for implantable medical devices |
| WO2008070353A2 (en) | 2006-11-07 | 2008-06-12 | Genentech, Inc. | Tissue plasminogen activator variant uses |
| WO2009155088A1 (en) * | 2008-05-30 | 2009-12-23 | University Of Cincinnati | Use of zinc chelators to inhibit biofilm formation |
| CN102159540B (zh) * | 2008-07-21 | 2015-08-12 | 布赖汉姆妇女医院 | 与合成的β-1,6葡糖胺寡糖相关的方法和组合物 |
| EP2318207A4 (de) * | 2008-08-28 | 2012-08-15 | Tyco Healthcare | Antimikrobielle fasern sowie entsprechende artikel und verfahren |
| US9622481B2 (en) | 2009-01-23 | 2017-04-18 | Kane Biotech Inc. | Biofilm-removing antimicrobial compositions and uses thereof |
| CA2750340C (en) | 2009-01-23 | 2017-09-19 | Kane Biotech Inc. | Biofilm-removing antimicrobial compositions and uses thereof |
| WO2010126607A2 (en) | 2009-04-30 | 2010-11-04 | President And Fellows Of Harvard College | Synthesis of tetracyclines and intermediates thereto |
| US20110066141A1 (en) * | 2009-09-11 | 2011-03-17 | Cook Incorporated | Implantable medical device having an anti-gastric distress agent |
| WO2012034032A2 (en) | 2010-09-10 | 2012-03-15 | The Board Of Regents Of Unbiversity Of Texas System | Antimicrobial solutions |
| CA2846891C (en) | 2011-08-31 | 2017-10-24 | Organic Medical Ventures, L.L.C. | Transdermal venous access locking solutions |
| ES2749223T3 (es) | 2013-04-16 | 2020-03-19 | Univ Cincinnati | Composiciones antimicrobianas de antibióticos aminoglicosídicos y quelantes de iones de zinc |
| CN108697827A (zh) | 2015-11-05 | 2018-10-23 | 得克萨斯州大学系统董事会 | 具有增强稳定性的抗微生物溶液 |
| WO2017134049A1 (en) | 2016-02-01 | 2017-08-10 | Schierholz Jörg Michael | Implantable medical products, a process for the preparation thereof, and use thereof |
| WO2017147067A1 (en) | 2016-02-22 | 2017-08-31 | Board Of Regents, The University Of Texas System | Antimicrobial compositions and uses thereof |
| GB201607814D0 (en) | 2016-05-04 | 2016-06-15 | 5D Health Prot Group Ltd | Anti-microbial compositions |
| WO2018226334A1 (en) * | 2017-06-06 | 2018-12-13 | St. Jude Medical, Cardiology Division, Inc. | Electrophysiology Device with Ion-Selective Electrodes |
| US12397014B2 (en) | 2019-02-05 | 2025-08-26 | The Brigham And Women's Hospital, Inc. | Polysaccharide compositions for use in treating filariasis |
| US11738120B1 (en) | 2022-04-14 | 2023-08-29 | Cormedix Inc. | Synthesis of taurolidine, purity profiles and polymorphs |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CS179567B1 (en) * | 1974-11-25 | 1977-11-30 | Vladimir Stoy | Ionogennic hydrophilic in water insoluble gels based on partial saponificated polymers or copolymers acrylonitrile and method of preparing them |
| US4442133A (en) * | 1982-02-22 | 1984-04-10 | Greco Ralph S | Antibiotic bonding of vascular prostheses and other implants |
| DK119884A (da) * | 1983-03-18 | 1984-09-19 | Lilly Co Eli | Fast, cylindrisk, subkutan implantation og dens anvendelse |
| US4678660A (en) * | 1984-12-07 | 1987-07-07 | Deseret Medical, Inc. | Thermoplastic polyurethane anticoagulant alloy coating |
| US4917686A (en) * | 1985-12-16 | 1990-04-17 | Colorado Biomedical, Inc. | Antimicrobial device and method |
| US4749585A (en) * | 1986-04-11 | 1988-06-07 | University Of Medicine And Dentistry Of New Jersey | Antibiotic bonded prosthesis and process for producing same |
| US4895566A (en) * | 1986-07-25 | 1990-01-23 | C. R. Bard, Inc. | Coating medical devices with cationic antibiotics |
| US5202449A (en) * | 1987-07-28 | 1993-04-13 | Nippon Kayaku Kabushiki Kaisha | Process for purifying 7-dimethylamino-6-demethyl-6-deoxytetracycline |
| US4846844A (en) * | 1987-08-31 | 1989-07-11 | Eli Lilly And Company | Antimicrobial coated implants |
| US5013306A (en) * | 1989-01-18 | 1991-05-07 | Becton, Dickinson And Company | Anti-infective and antithrombogenic medical articles and method for their preparation |
| US5217493A (en) * | 1992-03-11 | 1993-06-08 | Board Of Regents, The University Of Texas System | Antibacterial coated medical implants |
| FR2698025B1 (fr) * | 1992-11-13 | 1994-12-16 | Innovation Ingenierie Integrat | Dispositif de récupération et de stockage de déchets. |
-
1992
- 1992-11-12 US US07/975,486 patent/US5362754A/en not_active Expired - Lifetime
-
1993
- 1993-11-12 AT AT94901405T patent/ATE222126T1/de not_active IP Right Cessation
- 1993-11-12 JP JP6512342A patent/JPH08503400A/ja active Pending
- 1993-11-12 EP EP94901405A patent/EP0668720B1/de not_active Expired - Lifetime
- 1993-11-12 AU AU56003/94A patent/AU673400B2/en not_active Ceased
- 1993-11-12 WO PCT/US1993/010893 patent/WO1994010838A1/en not_active Ceased
- 1993-11-12 DE DE69332204T patent/DE69332204T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69332204T2 (de) | 2002-12-12 |
| AU5600394A (en) | 1994-06-08 |
| EP0668720B1 (de) | 2002-08-14 |
| EP0668720A1 (de) | 1995-08-30 |
| DE69332204D1 (de) | 2002-09-19 |
| US5362754A (en) | 1994-11-08 |
| WO1994010838A1 (en) | 1994-05-26 |
| AU673400B2 (en) | 1996-11-07 |
| JPH08503400A (ja) | 1996-04-16 |
| EP0668720A4 (de) | 1999-09-01 |
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