ATE223059T1 - Cyanidfreies reagens und verfahren zur bestimmung von hämoglobin - Google Patents

Cyanidfreies reagens und verfahren zur bestimmung von hämoglobin

Info

Publication number: ATE223059T1
Authority: AT; Austria
Prior art keywords: reagent; cyanide; blood sample; group; free
Prior art date: 1994-03-11

Application number

AT95912800T

Other languages

English (en)

Inventor

Young Ran Kim

Stephen D Stroupe

Original Assignee

Abbott Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-03-11

Filing date

1995-03-06

Publication date

2002-09-15

1995-03-06 Application filed by Abbott Lab filed Critical Abbott Lab

2002-09-15 Application granted granted Critical

2002-09-15 Publication of ATE223059T1 publication Critical patent/ATE223059T1/de

Links

239000003153 chemical reaction reagent Substances 0.000 title abstract 5
102000001554 Hemoglobins Human genes 0.000 title abstract 2
108010054147 Hemoglobins Proteins 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
KDCGOANMDULRCW-UHFFFAOYSA-N 7H-purine Chemical compound N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 abstract 2
JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 abstract 2
239000008280 blood Substances 0.000 abstract 2
210000004369 blood Anatomy 0.000 abstract 2
AWJUIBRHMBBTKR-UHFFFAOYSA-N isoquinoline Chemical compound C1=NC=CC2=CC=CC=C21 AWJUIBRHMBBTKR-UHFFFAOYSA-N 0.000 abstract 2
ZCQWOFVYLHDMMC-UHFFFAOYSA-N Oxazole Chemical compound C1=COC=N1 ZCQWOFVYLHDMMC-UHFFFAOYSA-N 0.000 abstract 1
WTKZEGDFNFYCGP-UHFFFAOYSA-N Pyrazole Chemical compound C=1C=NNC=1 WTKZEGDFNFYCGP-UHFFFAOYSA-N 0.000 abstract 1
CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 abstract 1
FZWLAAWBMGSTSO-UHFFFAOYSA-N Thiazole Chemical compound C1=CSC=N1 FZWLAAWBMGSTSO-UHFFFAOYSA-N 0.000 abstract 1
238000002835 absorbance Methods 0.000 abstract 1
RRUDCFGSUDOHDG-UHFFFAOYSA-N acetohydroxamic acid Chemical compound CC(O)=NO RRUDCFGSUDOHDG-UHFFFAOYSA-N 0.000 abstract 1
229960001171 acetohydroxamic acid Drugs 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
SYELZBGXAIXKHU-UHFFFAOYSA-N dodecyldimethylamine N-oxide Chemical compound CCCCCCCCCCCC[N+](C)(C)[O-] SYELZBGXAIXKHU-UHFFFAOYSA-N 0.000 abstract 1
230000001545 erythrolytic effect Effects 0.000 abstract 1
150000002460 imidazoles Chemical class 0.000 abstract 1
229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 abstract 1
239000003446 ligand Substances 0.000 abstract 1
UYDLBVPAAFVANX-UHFFFAOYSA-N octylphenoxy polyethoxyethanol Chemical compound CC(C)(C)CC(C)(C)C1=CC=C(OCCOCCOCCOCCO)C=C1 UYDLBVPAAFVANX-UHFFFAOYSA-N 0.000 abstract 1
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
239000004094 surface-active agent Substances 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Immunology (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Molecular Biology (AREA)
Cell Biology (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Ecology (AREA)
Tropical Medicine & Parasitology (AREA)
Investigating Or Analysing Biological Materials (AREA)

AT95912800T 1994-03-11 1995-03-06 Cyanidfreies reagens und verfahren zur bestimmung von hämoglobin ATE223059T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US21262694A	1994-03-11	1994-03-11
PCT/US1995/002897 WO1995024651A1 (en)	1994-03-11	1995-03-06	Cyanide-free reagent and method for the determination of hemoglobin

Publications (1)

Publication Number	Publication Date
ATE223059T1 true ATE223059T1 (de)	2002-09-15

Family

ID=22791814

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95912800T ATE223059T1 (de)	1994-03-11	1995-03-06	Cyanidfreies reagens und verfahren zur bestimmung von hämoglobin

Country Status (9)

Country	Link
US (2)	US5612223A (de)
EP (1)	EP0749583B1 (de)
JP (1)	JP3523878B2 (de)
AT (1)	ATE223059T1 (de)
AU (1)	AU1984295A (de)
CA (1)	CA2183558C (de)
DE (1)	DE69527947T2 (de)
ES (1)	ES2184795T3 (de)
WO (1)	WO1995024651A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1996002841A1 (en) *	1994-07-14	1996-02-01	Abbott Laboratories	Methods and reagents for cyanide-free determination of hemoglobin and leukocytes in whole blood
US5834315A (en) *	1994-12-23	1998-11-10	Coulter Corporation	Cyanide-free reagent and method for hemoglobin determination and leukocyte differentitation
US5763280A (en) *	1997-01-21	1998-06-09	Coulter International Corp.	Cyanide-free lytic reagent composition and method for hemoglobin and cell analysis
US5882934A (en) *	1997-01-21	1999-03-16	Coulter International Corp.	Composition and method for hemoglobin and cell analysis
US5858794A (en) *	1997-05-13	1999-01-12	Bayer Corporation	Cyanide-containing hemoglobin reagent composition and method providing acceptable precision, accuracy and freedom from white cell interference on automated hematology analyzers
US5935857A (en) *	1997-08-01	1999-08-10	Coulter International Corp.	Blood diluent
US6074881A (en) *	1998-08-03	2000-06-13	Bayer Corporation	Method for the prevention of hemoglobin interference in reagent systems for measuring peroxidase activity
DE19835243A1 (de) *	1998-08-04	2000-02-24	Lmb Technologie Gmbh	Vorrichtung und Verfahren zum Bestimmen eines Hämoglobinwerts von Blut
JPWO2002021142A1 (ja) *	2000-09-07	2004-01-15	和光純薬工業株式会社	総ヘモグロビン及び糖化ヘモグロビンの測定方法
GB0110053D0 (en) *	2001-04-24	2001-06-13	Axis Shield Asa	Assay
US6573102B2 (en)	2001-07-27	2003-06-03	Coulter International Corp.	Lytic reagent composition for determination of nucleated blood cells
US6916658B2 (en)	2001-07-27	2005-07-12	Beckman Coulter, Inc.	Method for measurement of immature granulocytes
CN1276252C (zh)	2001-07-27	2006-09-20	贝克曼库尔特有限公司	有核红细胞的测量方法
US6410330B1 (en)	2001-07-27	2002-06-25	Coulter International Corp.	Method for measurement of nucleated red blood cells
US6890756B2 (en) *	2002-04-05	2005-05-10	Streck Laboratories, Inc.	Method of using cyanide-free lyse solution to emulate a cyanide-containing lyse solution in the measurement of hemoglobin
IES20020936A2 (en) *	2002-12-03	2003-11-26	Trinity Res Ltd	A cyanide-free reagent for measuring haemoglobin in blood, and a method for measuring haemoglobin
ATE464562T1 (de) *	2004-10-20	2010-04-15	Chempaq As	Lysereagens zur gleichzeitigen auszählung unterschiedlicher arten von blutzellen in einer blutprobe
US7235404B2 (en)	2005-05-04	2007-06-26	Beckman Coulter, Inc.	Cyanide-free lytic reagent composition and method of use for hemoglobin and white blood cell measurement
DE102005060993A1 (de) *	2005-12-20	2007-06-28	Medisynthana Diagnostics Gmbh & Co. Kg	Konversionsreagenz sowie Verfahren und Kit zur Bestimmung des Hämoglobins
WO2007084977A2 (en) *	2006-01-20	2007-07-26	Beckman Coulter, Inc.	Low hemoglobin concentration cell percentage and method of use in detection of iron deficiency
GB2445441B (en) *	2006-09-26	2010-06-30	Ge Healthcare Bio Sciences	Nucleic acid purification method
GB2445442A (en) *	2006-09-26	2008-07-09	Ge Healthcare Bio Sciences	Nucleic acid purification using anion exchange
GB2443505B (en) *	2006-09-26	2008-12-31	Ge Healthcare Bio Sciences	Nucleic acid purification method
EP2250182B1 (de) *	2008-02-07	2015-12-02	GE Healthcare Bio-Sciences Corp.	Isolierung von dna, rna und protein aus einer einzelnen probe
US8192995B2 (en)	2008-11-13	2012-06-05	Beckman Coulter, Inc.	Method of correction of particle interference to hemoglobin measurement
US8614066B2 (en)	2009-08-26	2013-12-24	Abbott Laboratories	Method of using ligand-free lysing agent in hemoglobin analysis
US20140152801A1 (en)	2009-10-28	2014-06-05	Alentic Microscience Inc.	Detecting and Using Light Representative of a Sample
US8603309B2 (en) *	2011-09-12	2013-12-10	Nova Biomedical Corporation	Disposable sensor for electrochemical detection of hemoglobin
US10502666B2 (en)	2013-02-06	2019-12-10	Alentic Microscience Inc.	Sample processing improvements for quantitative microscopy
WO2014205576A1 (en)	2013-06-26	2014-12-31	Alentic Microscience Inc.	Sample processing improvements for microscopy
CN103698501B (zh) *	2013-12-23	2015-07-29	深圳开立生物医疗科技股份有限公司	一种无氰化物溶血剂
GB201716136D0 (en) *	2017-10-03	2017-11-15	Cyanoguard Ag	Process
CN107907690B (zh) *	2017-11-15	2020-07-10	南通伊仕生物技术股份有限公司	一种超敏c反应蛋白检测试剂盒及其使用方法
US20210278422A1 (en) *	2018-09-12	2021-09-09	Sekisui Medical Co., Ltd.	Reagent and method for measuring hemoglobins
JP2023027418A (ja) *	2019-12-12	2023-03-02	Ｐｈｃホールディングス株式会社	糖化ヘモグロビンの電気化学測定方法およびそれに用いる測定キット

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4200435A (en) *	1978-12-26	1980-04-29	Abbott Laboratories	Determination of glycosylated hemoglobin in blood
US4255385A (en) *	1979-10-23	1981-03-10	Abbott Laboratories	Reagent and test kit for determining glycosylated hemoglobin
US4274978A (en) *	1979-12-07	1981-06-23	Abbott Laboratories	Standards for determining glycosylated hemoglobin
CA1263590C (en) *	1984-12-06	1989-12-05		CYANIDE-FREE REAGENT FOR THE DETERMINATION OF HEMOGLOBIN
US4853338A (en) *	1987-05-20	1989-08-01	Technicon Instruments Corporation	Cyanide-free hemoglobin reagent
JP2619900B2 (ja) *	1988-01-27	1997-06-11	東亜医用電子株式会社	血液中の白血球およびヘモグロビンの測定用試薬および方法
JP2836865B2 (ja) *	1989-10-23	1998-12-14	東亜医用電子株式会社	血液中の白血球およびヘモグロビンの測定用試薬
US5242832A (en) *	1990-03-01	1993-09-07	Toa Medical Electronics Co., Ltd.	Reagent for measurement of leukocytes and hemoglobin in blood
GB9024771D0 (en) *	1990-11-14	1991-01-02	Axis Research	Assay

1995
- 1995-03-06 AT AT95912800T patent/ATE223059T1/de not_active IP Right Cessation
- 1995-03-06 EP EP95912800A patent/EP0749583B1/de not_active Expired - Lifetime
- 1995-03-06 DE DE69527947T patent/DE69527947T2/de not_active Expired - Lifetime
- 1995-03-06 WO PCT/US1995/002897 patent/WO1995024651A1/en not_active Ceased
- 1995-03-06 ES ES95912800T patent/ES2184795T3/es not_active Expired - Lifetime
- 1995-03-06 JP JP52362295A patent/JP3523878B2/ja not_active Expired - Fee Related
- 1995-03-06 CA CA002183558A patent/CA2183558C/en not_active Expired - Fee Related
- 1995-03-06 AU AU19842/95A patent/AU1984295A/en not_active Abandoned
- 1995-08-31 US US08/524,128 patent/US5612223A/en not_active Expired - Lifetime
1996
- 1996-10-15 US US08/730,193 patent/US5866428A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ES2184795T3 (es)	2003-04-16
CA2183558A1 (en)	1995-09-14
EP0749583A1 (de)	1996-12-27
US5612223A (en)	1997-03-18
JPH09511575A (ja)	1997-11-18
DE69527947T2 (de)	2003-05-28
EP0749583B1 (de)	2002-08-28
DE69527947D1 (de)	2002-10-02
US5866428A (en)	1999-02-02
JP3523878B2 (ja)	2004-04-26
AU1984295A (en)	1995-09-25
CA2183558C (en)	2006-01-24
WO1995024651A1 (en)	1995-09-14

Legal Events

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Description

2003-02-15

UEP

Publication of translation of european patent specification

Ref document number: 0749583

Country of ref document: EP

2005-12-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE223059T1 (de)	2002-09-15	Cyanidfreies reagens und verfahren zur bestimmung von hämoglobin
DE3853671D1 (de)	1995-06-01	Reagens und Verfahren zur Messung von Leukozyten und Hämoglobin im Blut.
ATE223044T1 (de)	2002-09-15	Nachweis von retikulozyten mit coriphosphin o
ATA59196A (de)	1997-06-15	Vorrichtung und verfahren zur bestimmung der konzentration von hämoglobinderivaten in einer unverdünnten unhämolysierten vollblutprobe
DE69016377D1 (de)	1995-03-09	Reagenz und Verfahren zur Verwendung desselben in der automatischen durchflusszytometrischen Bestimmung von mindestens einer Leukocyten-Subpopulation aus Vollblut.
DE69623174D1 (de)	2002-10-02	Verfahren und Reagenszusammensetzung zur Durchführung von differenzierenden Leukocytzählungen in frischen und gealteren Vollblutproben, auf der Grundlage der bereitsvorhandenen Peroxidaseaktivität der Leukocyten
IL103056A (en)	1997-04-15	Method for sphering of red blood cells
ATE219245T1 (de)	2002-06-15	Biosensor, iontophoretischen probenahmesystem, und verfahren zur seiner anwendung
ATE83561T1 (de)	1993-01-15	Denaturierende reagenzien zur bestimmung von haemoglobinderivaten im blut.
EP0869347A3 (de)	2000-02-23	Verfahren und Reagent zur Identifikation von Retikulozyten, Erythrozyten und Blutplättchen
DE69213315D1 (de)	1996-10-10	Reagenzien und Verfahren zur Zellanalyse im Harn
ATE360090T1 (de)	2007-05-15	Vorrichtung und verfahren zum bestimmen der koagulation in flüssigproben
DE59007613D1 (de)	1994-12-08	Verfahren zum Nachweis und zur Bestimmung von Humanserumalbumin in biologischen Flüssigkeiten mit Hilfe fluorogener Cyanin-Farbstoffe.
CA2191614A1 (en)	1996-02-01	Methods and reagents for cyanide-free determination of hemoglobin and leukocytes in whole blood
ATE41058T1 (de)	1989-03-15	Verfahren zur kolorimetrischen bestimmung von polykarboxylnaten und sulfonaten in waessrigen medien.
CA2149903A1 (en)	1995-04-13	Use of capillary electrophoresis for quantitating the concentration of protein components and of the total protein in fluids
DE68917613D1 (de)	1994-09-29	Natriumdecylsulfat enthaltende Waschlösung, Testsatz und Verfahren zur Bestimmung eines immunologischen Liganden.
ATE74211T1 (de)	1992-04-15	Verfahren zum nachweis eines analyten sowie hierfuer geeignetes mittel.
DE59510217D1 (de)	2002-07-04	Verfahren zur Reduzierung der Beeinflussung von diagnostischen Tests durch Heparin unter Verwendung von Metallsalzen und diagnostisches Reagenz für diagnostische Tests zur Bestimmung der Gerinnungsfähigkeit des Blutes enthaltend Metallsalze
DE3765147D1 (de)	1990-10-31	Verfahren und reagenz zur bestimmung von gesamt-bilirubin.
DE69124030D1 (de)	1997-02-20	Testverfahren, die ein lösliches fibrinähnliches Monomer nutzen
ATE97501T1 (de)	1993-12-15	Reagens und verfahren zur bestimmung von haemoglobin im blut.
FI841145A7 (fi)	1984-10-01	Menetelmä hemoglobiinipitoisuuden kvantitatiiviseksi määrittämiseksi biologisessa näytteessä.
DE69430410D1 (de)	2002-05-23	Methode zum Nachweis von Fructosamin
DE69032131D1 (de)	1998-04-16	Verfahren und vorrichtung zur bestimmung von glykosyliertem protein