ATE224187T1 - Verfahren zur vorbeugung und behandlung des myokardialen stunnings - Google Patents
Verfahren zur vorbeugung und behandlung des myokardialen stunningsInfo
- Publication number
- ATE224187T1 ATE224187T1 AT98959929T AT98959929T ATE224187T1 AT E224187 T1 ATE224187 T1 AT E224187T1 AT 98959929 T AT98959929 T AT 98959929T AT 98959929 T AT98959929 T AT 98959929T AT E224187 T1 ATE224187 T1 AT E224187T1
- Authority
- AT
- Austria
- Prior art keywords
- preventing
- phospholamban
- treating myocardial
- myocardial stunning
- stunning
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nonmetallic Welding Materials (AREA)
- Soil Working Implements (AREA)
- Fertilizers (AREA)
- Processing Of Meat And Fish (AREA)
- Road Signs Or Road Markings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Quinoline Compounds (AREA)
- Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99014697A | 1997-12-12 | 1997-12-12 | |
| PCT/FI1998/000976 WO1999030696A1 (en) | 1997-12-12 | 1998-12-11 | A method for the prevention and treatment of stunned myocardium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE224187T1 true ATE224187T1 (de) | 2002-10-15 |
Family
ID=25535825
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98959929T ATE224187T1 (de) | 1997-12-12 | 1998-12-11 | Verfahren zur vorbeugung und behandlung des myokardialen stunnings |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5968959A (de) |
| EP (1) | EP1039884B1 (de) |
| JP (1) | JP2002508314A (de) |
| AT (1) | ATE224187T1 (de) |
| AU (1) | AU1565599A (de) |
| BR (1) | BR9813549A (de) |
| CA (1) | CA2311932A1 (de) |
| DE (1) | DE69808131T2 (de) |
| DK (1) | DK1039884T3 (de) |
| ES (1) | ES2184341T3 (de) |
| PT (1) | PT1039884E (de) |
| WO (1) | WO1999030696A1 (de) |
| ZA (1) | ZA9811180B (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19839499A1 (de) * | 1998-08-29 | 2000-03-02 | Merck Patent Gmbh | 2-Oxo-2H-chinolinderivate |
| EP1728516A1 (de) * | 1998-11-02 | 2006-12-06 | The Regents of the University of California | Methode zur Hemmung der Phospholamban Aktivität zur Behandlung von Herzkrankheiten und Herzversagen |
| CA2349758A1 (en) * | 1998-11-02 | 2000-05-11 | The Regents Of The University Of California | A method for inhibition of phospholamban activity for the treatment of cardiac disease and heart failure |
| JP2002062296A (ja) * | 2000-08-22 | 2002-02-28 | Yamaguchi Technology Licensing Organization Ltd | 心不全治療薬のスクリーニング方法 |
| WO2002022177A2 (en) | 2000-09-11 | 2002-03-21 | The Regents Of The University Of California | High efficiency cardiac gene transfer |
| WO2004017922A2 (en) * | 2002-08-23 | 2004-03-04 | University Of Connecticut | Keto cannabinoids with therapeutic indications |
| WO2005023292A1 (en) | 2003-09-03 | 2005-03-17 | The General Hospital Corporation | Methods of treating restenosis |
| AR055041A1 (es) * | 2005-03-23 | 2007-08-01 | Merck Frosst Canada Ltd | Tiadiazoles y oxadiazoles como inhibidores de la sintesis de leucotrienos. composiciones farmaceuticas. |
| EP1917245A1 (de) | 2005-08-21 | 2008-05-07 | Abbott GmbH & Co. KG | Heterocyclische verbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren |
| FR2970964B1 (fr) * | 2011-01-28 | 2013-12-13 | Univ Claude Bernard Lyon | Nouveaux derives d'azacoumarines presentant une activite inhibitrice des pompes mdr |
| US9334256B2 (en) * | 2011-06-15 | 2016-05-10 | Nono Inc. | Agents and methods for treating ischemic and other diseases |
| US20200347038A1 (en) | 2014-08-29 | 2020-11-05 | Russell Dahl | Quinolines that modulate serca and their use for treating disease |
| WO2016032569A1 (en) * | 2014-08-29 | 2016-03-03 | Celladon Corporation | Quinolines and their use for treating endoplasmic reticulum stress-caused diseases |
| US11730729B2 (en) | 2020-07-20 | 2023-08-22 | Neurodon Corporation | Quinolines that modulate SERCA and their use for treating disease |
| UY40699A (es) | 2023-04-05 | 2024-08-30 | Ionis Pharmaceuticals Inc | Compuestos y métodos para reducir la expresión de pln |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3259635A (en) * | 1962-07-26 | 1966-07-05 | Cassella Farbwerke Mainkur Ag | 7-hydroxy coumarin derivative |
| US3515721A (en) * | 1967-06-26 | 1970-06-02 | Cassella Farbwerke Mainkur Ag | 3-tertiary-aminoethyl-4-methyl or phenyl-7-ethoxycarbonylmethoxy - halo or mononitro coumarins and congeners |
| IT1088554B (it) * | 1977-11-17 | 1985-06-10 | F I D I A Spa | Procedimento sellettivo per la preparazione di derivati della 7-indrossi cumarina |
| IT1160365B (it) * | 1978-12-19 | 1987-03-11 | F I D I A Spa | Applicazioni in campo farmacologico e terapeutico dell'8-cloro-3-(beta-dietilamincetil)-4-metil-7-etossi-carbonilmetossicumarina cloridrato preparato allo stato puro mediante procedimento selettivo, con particolare riguardo alla sua azione antiaritmica |
| CA2294550A1 (en) * | 1997-06-25 | 1999-01-07 | Orion Corporation | Use of phospholamban inhibitors for increasing coronary flow |
-
1998
- 1998-11-10 US US09/188,707 patent/US5968959A/en not_active Expired - Fee Related
- 1998-12-07 ZA ZA9811180A patent/ZA9811180B/xx unknown
- 1998-12-11 CA CA002311932A patent/CA2311932A1/en not_active Abandoned
- 1998-12-11 AT AT98959929T patent/ATE224187T1/de not_active IP Right Cessation
- 1998-12-11 ES ES98959929T patent/ES2184341T3/es not_active Expired - Lifetime
- 1998-12-11 DK DK98959929T patent/DK1039884T3/da active
- 1998-12-11 BR BR9813549-0A patent/BR9813549A/pt not_active IP Right Cessation
- 1998-12-11 AU AU15655/99A patent/AU1565599A/en not_active Abandoned
- 1998-12-11 WO PCT/FI1998/000976 patent/WO1999030696A1/en not_active Ceased
- 1998-12-11 PT PT98959929T patent/PT1039884E/pt unknown
- 1998-12-11 DE DE69808131T patent/DE69808131T2/de not_active Expired - Fee Related
- 1998-12-11 JP JP2000538679A patent/JP2002508314A/ja active Pending
- 1998-12-11 EP EP98959929A patent/EP1039884B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PT1039884E (pt) | 2003-01-31 |
| ZA9811180B (en) | 1999-06-09 |
| DK1039884T3 (da) | 2002-12-09 |
| DE69808131T2 (de) | 2003-06-05 |
| BR9813549A (pt) | 2000-10-10 |
| CA2311932A1 (en) | 1999-06-24 |
| DE69808131D1 (de) | 2002-10-24 |
| EP1039884B1 (de) | 2002-09-18 |
| ES2184341T3 (es) | 2003-04-01 |
| EP1039884A1 (de) | 2000-10-04 |
| US5968959A (en) | 1999-10-19 |
| WO1999030696A1 (en) | 1999-06-24 |
| AU1565599A (en) | 1999-07-05 |
| JP2002508314A (ja) | 2002-03-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1039884 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |