ATE224716T1 - Pharmazeutische zusammensetzungen von cinchonin dihydrochlorid - Google Patents

Pharmazeutische zusammensetzungen von cinchonin dihydrochlorid

Info

Publication number: ATE224716T1
Authority: AT; Austria
Prior art keywords: pharmaceutical compositions; cinchonine; dihydrochloride; cinchonine dihydrochloride; compositions containing
Prior art date: 1997-06-11

Application number

AT98929515T

Other languages

English (en)

Inventor

Philippe Genne

Houssam Ibrahim

Original Assignee

Debiopharm Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-11

Filing date

1998-06-08

Publication date

2002-10-15

1998-06-08 Application filed by Debiopharm Sa filed Critical Debiopharm Sa

2002-10-15 Application granted granted Critical

2002-10-15 Publication of ATE224716T1 publication Critical patent/ATE224716T1/de

Links

ZDBQDNUZNQOCTH-OPMVAYRNSA-N (s)-[(2r,4s,5r)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol;dihydrochloride Chemical group Cl.Cl.C1=CC=C2C([C@@H]([C@@H]3N4CC[C@H]([C@H](C4)C=C)C3)O)=CC=NC2=C1 ZDBQDNUZNQOCTH-OPMVAYRNSA-N 0.000 title abstract 4
239000008194 pharmaceutical composition Substances 0.000 title abstract 3
206010048723 Multiple-drug resistance Diseases 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
KMPWYEUPVWOPIM-UHFFFAOYSA-N cinchonidine Natural products C1=CC=C2C(C(C3N4CCC(C(C4)C=C)C3)O)=CC=NC2=C1 KMPWYEUPVWOPIM-UHFFFAOYSA-N 0.000 abstract 1
KMPWYEUPVWOPIM-LSOMNZGLSA-N cinchonine Chemical compound C1=CC=C2C([C@@H]([C@H]3N4CC[C@H]([C@H](C4)C=C)C3)O)=CC=NC2=C1 KMPWYEUPVWOPIM-LSOMNZGLSA-N 0.000 abstract 1
LOUPRKONTZGTKE-UHFFFAOYSA-N cinchonine Natural products C1C(C(C2)C=C)CCN2C1C(O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-UHFFFAOYSA-N 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/49—Cinchonan derivatives, e.g. quinine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Orthopedic Medicine & Surgery (AREA)
Tropical Medicine & Parasitology (AREA)
Pain & Pain Management (AREA)
Physical Education & Sports Medicine (AREA)
Epidemiology (AREA)
Biomedical Technology (AREA)
Cardiology (AREA)
Neurosurgery (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT98929515T 1997-06-11 1998-06-08 Pharmazeutische zusammensetzungen von cinchonin dihydrochlorid ATE224716T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9707234A FR2764509A1 (fr)	1997-06-11	1997-06-11	Compositions pharmaceutiques contenant du dichlorhydrate de cinchonine
PCT/FR1998/001166 WO1998056383A1 (fr)	1997-06-11	1998-06-08	Compositions pharmaceutiques contenant du dichlorhydrate de cinchonine

Publications (1)

Publication Number	Publication Date
ATE224716T1 true ATE224716T1 (de)	2002-10-15

Family

ID=9507852

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98929515T ATE224716T1 (de)	1997-06-11	1998-06-08	Pharmazeutische zusammensetzungen von cinchonin dihydrochlorid

Country Status (14)

Country	Link
US (1)	US6528524B2 (de)
EP (1)	EP0986390B1 (de)
JP (1)	JP2002504109A (de)
CN (1)	CN1189174C (de)
AT (1)	ATE224716T1 (de)
AU (1)	AU740642B2 (de)
CA (1)	CA2295704A1 (de)
DE (1)	DE69808287T2 (de)
DK (1)	DK0986390T3 (de)
ES (1)	ES2184285T3 (de)
FR (1)	FR2764509A1 (de)
IL (2)	IL133222A0 (de)
PT (1)	PT986390E (de)
WO (1)	WO1998056383A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US9301956B2 (en) *	2014-02-12	2016-04-05	Adam Mickiewicz University	Application of cinchona alkaloid derivatives as cytotoxic compounds
US11066421B1 (en) *	2021-02-09	2021-07-20	Ares Pharmaceuticals, LLC	Synthetic cinchona alkaloids against cancer
US11649232B2 (en)	2021-05-10	2023-05-16	Ares Pharmaceuticals, LLC	Synthetic dimeric cinchona alkaloids against cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1981003564A1 (en)	1980-05-27	1981-12-10	C Rose	Drum pitch modulation
AU649787B2 (en) *	1991-02-25	1994-06-02	Debiopharm S.A.	Therapeutic agents for the treatment of multidrug resistance to cancers
NZ247516A (en) *	1993-04-28	1995-02-24	Bernard Charles Sherman	Water dispersible pharmaceutical compositions comprising drug dissolved in solvent system comprising at least one alcohol and at least one surfactant

1997
- 1997-06-11 FR FR9707234A patent/FR2764509A1/fr not_active Revoked
1998
- 1998-06-08 AT AT98929515T patent/ATE224716T1/de not_active IP Right Cessation
- 1998-06-08 CA CA002295704A patent/CA2295704A1/fr not_active Abandoned
- 1998-06-08 US US09/424,943 patent/US6528524B2/en not_active Expired - Fee Related
- 1998-06-08 ES ES98929515T patent/ES2184285T3/es not_active Expired - Lifetime
- 1998-06-08 CN CNB988060698A patent/CN1189174C/zh not_active Expired - Fee Related
- 1998-06-08 DK DK98929515T patent/DK0986390T3/da active
- 1998-06-08 PT PT98929515T patent/PT986390E/pt unknown
- 1998-06-08 WO PCT/FR1998/001166 patent/WO1998056383A1/fr not_active Ceased
- 1998-06-08 DE DE69808287T patent/DE69808287T2/de not_active Expired - Fee Related
- 1998-06-08 EP EP98929515A patent/EP0986390B1/de not_active Expired - Lifetime
- 1998-06-08 IL IL13322298A patent/IL133222A0/xx not_active IP Right Cessation
- 1998-06-08 AU AU79244/98A patent/AU740642B2/en not_active Ceased
- 1998-06-08 JP JP50176199A patent/JP2002504109A/ja not_active Ceased
1999
- 1999-11-30 IL IL133222A patent/IL133222A/en unknown

Also Published As

Publication number	Publication date
CN1189174C (zh)	2005-02-16
AU740642B2 (en)	2001-11-08
ES2184285T3 (es)	2003-04-01
AU7924498A (en)	1998-12-30
DK0986390T3 (da)	2003-01-27
DE69808287D1 (de)	2002-10-31
PT986390E (pt)	2003-01-31
IL133222A (en)	2006-08-01
IL133222A0 (en)	2001-03-19
WO1998056383A1 (fr)	1998-12-17
US6528524B2 (en)	2003-03-04
CN1259869A (zh)	2000-07-12
US20020091136A1 (en)	2002-07-11
EP0986390B1 (de)	2002-09-25
CA2295704A1 (fr)	1998-12-17
FR2764509A1 (fr)	1998-12-18
EP0986390A1 (de)	2000-03-22
JP2002504109A (ja)	2002-02-05
DE69808287T2 (de)	2003-06-26

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2003-04-15

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Publication of translation of european patent specification

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2008-03-15

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