ATE22533T1 - PHARMACEUTICAL COMPOSITION. - Google Patents
PHARMACEUTICAL COMPOSITION.Info
- Publication number
- ATE22533T1 ATE22533T1 AT83302032T AT83302032T ATE22533T1 AT E22533 T1 ATE22533 T1 AT E22533T1 AT 83302032 T AT83302032 T AT 83302032T AT 83302032 T AT83302032 T AT 83302032T AT E22533 T1 ATE22533 T1 AT E22533T1
- Authority
- AT
- Austria
- Prior art keywords
- pharmaceutical composition
- gamma
- linolenic acid
- troxerutin
- bioflavonoid
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- IKGXIBQEEMLURG-NVPNHPEKSA-N rutin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-NVPNHPEKSA-N 0.000 abstract 3
- HOBAELRKJCKHQD-UHFFFAOYSA-N (8Z,11Z,14Z)-8,11,14-eicosatrienoic acid Natural products CCCCCC=CCC=CCC=CCCCCCCC(O)=O HOBAELRKJCKHQD-UHFFFAOYSA-N 0.000 abstract 1
- JMGZEFIQIZZSBH-UHFFFAOYSA-N Bioquercetin Natural products CC1OC(OCC(O)C2OC(OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5)C(O)C2O)C(O)C(O)C1O JMGZEFIQIZZSBH-UHFFFAOYSA-N 0.000 abstract 1
- 235000021298 Dihomo-γ-linolenic acid Nutrition 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 230000002950 deficient Effects 0.000 abstract 1
- HOBAELRKJCKHQD-QNEBEIHSSA-N dihomo-γ-linolenic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/CCCCCCC(O)=O HOBAELRKJCKHQD-QNEBEIHSSA-N 0.000 abstract 1
- IVTMALDHFAHOGL-UHFFFAOYSA-N eriodictyol 7-O-rutinoside Natural products OC1C(O)C(O)C(C)OC1OCC1C(O)C(O)C(O)C(OC=2C=C3C(C(C(O)=C(O3)C=3C=C(O)C(O)=CC=3)=O)=C(O)C=2)O1 IVTMALDHFAHOGL-UHFFFAOYSA-N 0.000 abstract 1
- 235000004626 essential fatty acids Nutrition 0.000 abstract 1
- VZCCETWTMQHEPK-UHFFFAOYSA-N gamma-Linolensaeure Natural products CCCCCC=CCC=CCC=CCCCCC(O)=O VZCCETWTMQHEPK-UHFFFAOYSA-N 0.000 abstract 1
- 235000020664 gamma-linolenic acid Nutrition 0.000 abstract 1
- VZCCETWTMQHEPK-QNEBEIHSSA-N gamma-linolenic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/CCCCC(O)=O VZCCETWTMQHEPK-QNEBEIHSSA-N 0.000 abstract 1
- 229960002733 gamolenic acid Drugs 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- FDRQPMVGJOQVTL-UHFFFAOYSA-N quercetin rutinoside Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 FDRQPMVGJOQVTL-UHFFFAOYSA-N 0.000 abstract 1
- ALABRVAAKCSLSC-UHFFFAOYSA-N rutin Natural products CC1OC(OCC2OC(O)C(O)C(O)C2O)C(O)C(O)C1OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5 ALABRVAAKCSLSC-UHFFFAOYSA-N 0.000 abstract 1
- 235000005493 rutin Nutrition 0.000 abstract 1
- 229960004555 rutoside Drugs 0.000 abstract 1
- 229960003232 troxerutin Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
A pharmaceutical composition comprises one or more essential fatty acids, for example, gamma -linolenic acid or dihomo- gamma -linolenic acid, in conjunction with rutin, troxerutin or other bioflavonoid. The composition is useful in the treatment of inflammation or defective T-lymphocyte function.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8212433 | 1982-04-29 | ||
| EP83302032A EP0093516B1 (en) | 1982-04-29 | 1983-04-12 | Pharmaceutical composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE22533T1 true ATE22533T1 (en) | 1986-10-15 |
Family
ID=10530062
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT83302032T ATE22533T1 (en) | 1982-04-29 | 1983-04-12 | PHARMACEUTICAL COMPOSITION. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4888326A (en) |
| EP (1) | EP0093516B1 (en) |
| JP (1) | JPS58208234A (en) |
| AT (1) | ATE22533T1 (en) |
| AU (1) | AU554667B2 (en) |
| CA (1) | CA1209913A (en) |
| DE (1) | DE3366530D1 (en) |
| IE (1) | IE54795B1 (en) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6121065A (en) * | 1984-07-10 | 1986-01-29 | Akira Kitano | Dietary supplement |
| JPS61103826A (en) * | 1984-10-25 | 1986-05-22 | Kao Corp | Anti-inflammatory agent |
| DE3615710A1 (en) * | 1986-05-09 | 1987-11-26 | Hoechst Ag | PREPARATIONS FOR THE SYNTHESIS OF PROSTAGLANDINES AND HYDROXY FATTY ACIDS IN BIOLOGICAL SYSTEMS |
| US5234952A (en) * | 1988-12-23 | 1993-08-10 | Nestec S.A. | Reduction of thrombogenicity with lipids of blackcurrant seed |
| CH676909A5 (en) * | 1988-12-23 | 1991-03-28 | Nestle Sa | |
| GB9111900D0 (en) * | 1991-06-03 | 1991-07-24 | Efamol Holdings | Fatty acid compositions |
| US5674901A (en) * | 1995-06-01 | 1997-10-07 | Wisconsin Alumni Research Foundation | Methods of treating animals to maintain or increase CD-4 and CD-8 cell populations |
| DE69420124T2 (en) * | 1993-01-15 | 2000-03-02 | Abbott Laboratories, Abbott Park | STRUCTURED LIPIDS |
| US5856149A (en) * | 1995-06-01 | 1999-01-05 | Wisconsin Alumni Research Foundation | Method of producing conjugated fatty acids |
| US5639460A (en) * | 1995-06-07 | 1997-06-17 | Raymond; Hal C. | Aqueous plant extract having antiviral activity |
| EP0941088B1 (en) * | 1996-11-05 | 2003-03-05 | Wisconsin Alumni Research Foundation | Use of conjugated linoleic acid to enhance natural killer lymphocyte function |
| US6107334A (en) * | 1998-02-23 | 2000-08-22 | Wake Forest University | Dietary control of arachidonic acid metabolism |
| US7138431B1 (en) * | 1998-02-23 | 2006-11-21 | Wake Forest University | Dietary control of arachidonic acid metabolism |
| WO2002009699A2 (en) * | 2000-07-28 | 2002-02-07 | Immupharm Aps | Method of treating symptoms of common cold, allergic rhinitis and infections relating to the respiratory tract |
| CA2436650A1 (en) | 2003-08-06 | 2005-02-06 | Naturia Inc. | Conjugated linolenic acid (clnatm) compositions: synthesis, purification and uses |
| MXPA04002940A (en) * | 2004-03-26 | 2005-09-28 | Velez Rivera Hector | PHYTO-COMPOSITION FOR THE TREATMENT OF ARTICULAR DISEASES. |
| ITMI20070555A1 (en) * | 2007-03-21 | 2007-06-20 | Giuliani Spa | COMPOSITION OF THE ACTIVITY OF INHIBITION ON THE 5 ALPHA-REDUCTASE |
| US8343753B2 (en) * | 2007-11-01 | 2013-01-01 | Wake Forest University School Of Medicine | Compositions, methods, and kits for polyunsaturated fatty acids from microalgae |
| GB0907413D0 (en) | 2009-04-29 | 2009-06-10 | Equateq Ltd | Novel methods |
| US8293790B2 (en) | 2011-10-19 | 2012-10-23 | Dignity Sciences Limited | Pharmaceutical compositions comprising DGLA and benzoyl peroxide and methods of use thereof |
| ES2784240T3 (en) | 2014-06-04 | 2020-09-23 | Ds Biopharma Ltd | Pharmaceutical compositions comprising DGLA and use thereof |
| US20210315851A1 (en) | 2020-04-03 | 2021-10-14 | Afimmune Limited | Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2893M (en) * | 1963-08-01 | 1964-11-02 | Jean Joseph Choukroun | Pharmaceutical composition based on vitamins. |
| GB1082624A (en) * | 1965-02-26 | 1967-09-06 | Calmic Ltd | Improvements in or relating to therapeutically active compounds |
| PT68117A (en) * | 1977-06-02 | 1978-06-01 | Sarget Lab | NOVEL PROCESS FOR THE PREPARATION OF BENZOPYRANIC GLYCOSIDE DERIVATIVES |
| IE47777B1 (en) * | 1978-01-23 | 1984-06-13 | Efamol Ltd | Pharmaceutical and dietary composition comprising gamma-linolenic acids |
| DE2967049D1 (en) * | 1978-04-11 | 1984-07-19 | Efamol Ltd | Pharmaceutical and dietary composition comprising gamma-linolenic acids |
| IE49783B1 (en) * | 1979-05-18 | 1985-12-11 | Efamol Ltd | Pharmaceutical and dietary composition comprising epsilon-linolenic acids |
-
1983
- 1983-04-12 AT AT83302032T patent/ATE22533T1/en not_active IP Right Cessation
- 1983-04-12 EP EP83302032A patent/EP0093516B1/en not_active Expired
- 1983-04-12 IE IE835/83A patent/IE54795B1/en not_active IP Right Cessation
- 1983-04-12 DE DE8383302032T patent/DE3366530D1/en not_active Expired
- 1983-04-22 AU AU13881/83A patent/AU554667B2/en not_active Ceased
- 1983-04-26 CA CA000426708A patent/CA1209913A/en not_active Expired
- 1983-04-28 JP JP58076016A patent/JPS58208234A/en active Pending
-
1988
- 1988-03-04 US US07/168,603 patent/US4888326A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA1209913A (en) | 1986-08-19 |
| IE830835L (en) | 1983-10-29 |
| AU1388183A (en) | 1983-11-03 |
| IE54795B1 (en) | 1990-02-14 |
| EP0093516B1 (en) | 1986-10-01 |
| EP0093516A1 (en) | 1983-11-09 |
| DE3366530D1 (en) | 1986-11-06 |
| JPS58208234A (en) | 1983-12-03 |
| US4888326A (en) | 1989-12-19 |
| AU554667B2 (en) | 1986-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |