ATE225518T1 - Verfahren zur elektronspinresonanz-verstärkten magnetresonanzabbildung (esremri) mit dynamischer ex vivo kernpolarisation einer magnetresonanzabbildungssubstanz - Google Patents

Verfahren zur elektronspinresonanz-verstärkten magnetresonanzabbildung (esremri) mit dynamischer ex vivo kernpolarisation einer magnetresonanzabbildungssubstanz

Info

Publication number
ATE225518T1
ATE225518T1 AT97930621T AT97930621T ATE225518T1 AT E225518 T1 ATE225518 T1 AT E225518T1 AT 97930621 T AT97930621 T AT 97930621T AT 97930621 T AT97930621 T AT 97930621T AT E225518 T1 ATE225518 T1 AT E225518T1
Authority
AT
Austria
Prior art keywords
magnetic resonance
resonance imaging
esremri
dynamic
electron spin
Prior art date
Application number
AT97930621T
Other languages
English (en)
Inventor
Ib Leunbach
Ian Young
Goesta Ehnholm
Georg Hansson
Stefan Petersson
Lars-Goran Wistrand
Klaes Golman
Original Assignee
Amersham Health As
Picker Nordstar Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham Health As, Picker Nordstar Oy filed Critical Amersham Health As
Application granted granted Critical
Publication of ATE225518T1 publication Critical patent/ATE225518T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/282—Means specially adapted for hyperpolarisation or for hyperpolarised contrast agents, e.g. for the generation of hyperpolarised gases using optical pumping cells, for storing hyperpolarised contrast agents or for the determination of the polarisation of a hyperpolarised contrast agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/62—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using double resonance

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • General Health & Medical Sciences (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Semiconductor Lasers (AREA)
AT97930621T 1996-07-05 1997-07-03 Verfahren zur elektronspinresonanz-verstärkten magnetresonanzabbildung (esremri) mit dynamischer ex vivo kernpolarisation einer magnetresonanzabbildungssubstanz ATE225518T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9614139.5A GB9614139D0 (en) 1996-07-05 1996-07-05 Method
PCT/GB1997/001804 WO1998001766A1 (en) 1996-07-05 1997-07-03 Method of electron spin resonance enhanced magnetic resonance imaging (esremri) with ex vivo dynamic nuclear polarisaton of an mr imaging agent

Publications (1)

Publication Number Publication Date
ATE225518T1 true ATE225518T1 (de) 2002-10-15

Family

ID=10796408

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97930621T ATE225518T1 (de) 1996-07-05 1997-07-03 Verfahren zur elektronspinresonanz-verstärkten magnetresonanzabbildung (esremri) mit dynamischer ex vivo kernpolarisation einer magnetresonanzabbildungssubstanz

Country Status (9)

Country Link
US (1) US6008644A (de)
EP (1) EP0909392B1 (de)
JP (1) JP4109719B2 (de)
AT (1) ATE225518T1 (de)
AU (1) AU3450497A (de)
DE (1) DE69716069T2 (de)
ES (1) ES2187794T3 (de)
GB (1) GB9614139D0 (de)
WO (1) WO1998001766A1 (de)

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EP0990168A1 (de) 1997-06-19 2000-04-05 Nycomed Imaging As Overhauser verfahren der magnetresonanz-bilderzeugung mit ex-vivo polarisierung eines magnetresonanz-bilderzeugungsmittels
US6278893B1 (en) * 1998-01-05 2001-08-21 Nycomed Imaging As Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent
DE19911043A1 (de) * 1999-03-12 2000-09-14 Philips Corp Intellectual Pty MR-Verfahren
GB9911679D0 (en) * 1999-05-19 1999-07-21 Nycomed Imaging As Magnetic resonance imaging
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GB0006207D0 (en) 2000-03-16 2000-05-03 Picker Nordstar Oy Nuclear magnetic resonance apparatus and method
US20040067591A1 (en) * 2002-10-04 2004-04-08 Wisconsin Alumni Research Foundation Tissue mimicking elastography phantoms
JP4639185B2 (ja) * 2003-04-15 2011-02-23 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 磁性粒子に作用して干渉物質を検出する方法および装置
WO2006064392A2 (en) * 2004-12-14 2006-06-22 Philips Intellectual Property & Standards Gmbh Method of determining a spatial distribution of magnetic particles
US20070025918A1 (en) * 2005-07-28 2007-02-01 General Electric Company Magnetic resonance imaging (MRI) agents: water soluble carbon-13 enriched fullerene and carbon nanotubes for use with dynamic nuclear polarization
ES2654520T3 (es) * 2005-10-11 2018-02-14 Huntington Medical Research Institutes Agentes de formación de imágenes y métodos de uso de los mismos
US8703102B2 (en) 2008-04-04 2014-04-22 Millikelvin Technologies Llc Systems and methods for producing hyperpolarized materials and mixtures thereof
WO2007136439A2 (en) 2006-02-21 2007-11-29 Avrum Belzer Hyperpolarization methods, systems and compositions
US7205764B1 (en) * 2006-04-11 2007-04-17 Varian, Inc. Method and apparatus for increasing the detection sensitivity in a high resolution NMR analysis
WO2008086534A1 (en) * 2007-01-11 2008-07-17 Huntington Medical Research Institutes Imaging agents and methods of use thereof
WO2009046457A2 (en) * 2007-10-05 2009-04-09 Huntington Medical Research Institutes Imaging of genetic material with magnetic resonance
WO2009129265A1 (en) * 2008-04-14 2009-10-22 Huntington Medical Research Institutes Methods and apparatus for pasadena hyperpolarization
WO2010037771A1 (en) * 2008-10-03 2010-04-08 Bracco Imaging Spa A process for the preparation of aqueous solutions of hyperpolarized molecules
JP5792726B2 (ja) 2009-08-31 2015-10-14 ミリケルビン テクノロジーズ エルエルシーＭｉｌｌｉｋｅｌｖｉｎ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｌｌｃ 過分極核を含む材料を作製する方法
US8970217B1 (en) 2010-04-14 2015-03-03 Hypres, Inc. System and method for noise reduction in magnetic resonance imaging
US9381257B2 (en) 2012-07-13 2016-07-05 Bracco Imaging S.P.A. Triarylmethyl radicals
US9874622B2 (en) 2013-09-27 2018-01-23 General Electric Company Hyperpolarized media transport vessel
JP6483108B2 (ja) 2013-10-28 2019-03-13 ブラッコ・イメージング・ソシエタ・ペル・アチオニＢｒａｃｃｏ Ｉｍａｇｉｎｇ Ｓ．Ｐ．Ａ． 超偏極カルボン酸塩化合物の製造方法
US10126438B2 (en) 2014-09-19 2018-11-13 University Of Virginia Patent Foundation Systems and methods for polarized nuclear imaging and spectroscopy
US11754652B2 (en) 2016-09-15 2023-09-12 University Of Virginia Patent Foundation Systems and methods for polarized nuclear imaging and spectroscopy
US10520561B2 (en) 2017-09-27 2019-12-31 General Electric Company System and method for hyperpolarizing a substance and quenching radicals therein
US10942237B2 (en) 2019-05-07 2021-03-09 GE Precision Healthcare LLC System and method for hyperpolarizing a substance
CN117148233B (zh) * 2023-10-31 2024-01-12 中国科学院精密测量科学与技术创新研究院 一种针对esr非均匀展宽的弱磁测量装置与方法

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FI85193C (fi) * 1989-11-27 1992-03-10 Instrumentarium Oy Undersoekningsfoerfarande och - anordning.
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DE19600241C2 (de) * 1995-01-13 2002-08-01 Bruker Biospin Gmbh Verfahren und Vorrichtung zum Auffinden von Edelsteinen in einer umgebenden Substanz mittels magnetischer Kernresonanz
US5678548A (en) * 1995-07-20 1997-10-21 The United States Of America As Represented By The Department Of Health And Human Services System and method for performing in vivo imaging and oxymetry and FT microscopy by pulsed radiofrequency electron paramagnetic resonance

Also Published As

Publication number Publication date
JP4109719B2 (ja) 2008-07-02
US6008644A (en) 1999-12-28
WO1998001766A1 (en) 1998-01-15
EP0909392B1 (de) 2002-10-02
EP0909392A1 (de) 1999-04-21
JP2000513979A (ja) 2000-10-24
GB9614139D0 (en) 1996-09-04
DE69716069T2 (de) 2003-06-26
DE69716069D1 (de) 2002-11-07
ES2187794T3 (es) 2003-06-16
AU3450497A (en) 1998-02-02

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