ATE225767T1 - 3,4-disubstituierte phenylethanolaminotetralin- carboxamid-derivate - Google Patents

3,4-disubstituierte phenylethanolaminotetralin- carboxamid-derivate

Info

Publication number
ATE225767T1
ATE225767T1 AT97902714T AT97902714T ATE225767T1 AT E225767 T1 ATE225767 T1 AT E225767T1 AT 97902714 T AT97902714 T AT 97902714T AT 97902714 T AT97902714 T AT 97902714T AT E225767 T1 ATE225767 T1 AT E225767T1
Authority
AT
Austria
Prior art keywords
carbon atom
amino
configuration
disubstituted
carboxamide derivatives
Prior art date
Application number
AT97902714T
Other languages
English (en)
Inventor
Makio Kitazawa
Kosuke Okazaki
Tetsuro Tamai
Masaru Saito
Nobuyuki Tanaka
Hiroaki Kobayashi
Ken Kikuchi
Hideyuki Muranaka
Original Assignee
Kissei Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=13386565&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE225767(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kissei Pharmaceutical filed Critical Kissei Pharmaceutical
Application granted granted Critical
Publication of ATE225767T1 publication Critical patent/ATE225767T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/04—Drugs for disorders of the urinary system for urolithiasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
AT97902714T 1996-02-19 1997-02-18 3,4-disubstituierte phenylethanolaminotetralin- carboxamid-derivate ATE225767T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6888596 1996-02-19
PCT/JP1997/000424 WO1997030023A1 (en) 1996-02-19 1997-02-18 3,4-disubstituted phenylethanolaminotetralincarboxamide derivatives

Publications (1)

Publication Number Publication Date
ATE225767T1 true ATE225767T1 (de) 2002-10-15

Family

ID=13386565

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97902714T ATE225767T1 (de) 1996-02-19 1997-02-18 3,4-disubstituierte phenylethanolaminotetralin- carboxamid-derivate

Country Status (24)

Country Link
US (1) US6133266A (de)
EP (1) EP0882704B1 (de)
JP (1) JP3892045B2 (de)
KR (1) KR100491633B1 (de)
CN (1) CN1100032C (de)
AT (1) ATE225767T1 (de)
AU (1) AU725042B2 (de)
BR (1) BR9707566B1 (de)
CA (1) CA2245490C (de)
CZ (1) CZ293974B6 (de)
DE (1) DE69716242T2 (de)
DK (1) DK0882704T3 (de)
EA (1) EA002143B1 (de)
ES (1) ES2184989T3 (de)
HU (1) HU229400B1 (de)
ID (1) ID16091A (de)
MY (1) MY123853A (de)
NO (1) NO323095B1 (de)
NZ (1) NZ331445A (de)
PL (1) PL186411B1 (de)
PT (1) PT882704E (de)
SG (1) SG72727A1 (de)
TW (1) TW375604B (de)
WO (1) WO1997030023A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999009001A1 (fr) * 1997-08-19 1999-02-25 Kissei Pharmaceutical Co., Ltd. Derives de phenylethanolaminotetraline et bronchodilatateurs
ZA994264B (en) 1998-07-01 2000-01-25 Warner Lambert Co Stereoisomers with high affinity for adrenergic receptors.
GB9913083D0 (en) * 1999-06-04 1999-08-04 Novartis Ag Organic compounds
US7232837B2 (en) 1999-06-29 2007-06-19 Mcneil-Ppc, Inc. Stereoisomers with high affinity for adrenergic receptors
FR2809725B1 (fr) * 2000-06-06 2004-05-07 Sanofi Synthelabo Propanolaminotetralines, leur preparation et compositions pharmaceutiques en contenant
GB0029562D0 (en) 2000-12-04 2001-01-17 Novartis Ag Organic compounds
US20060052458A1 (en) * 2003-01-22 2006-03-09 Kissei Pharmaceutical Co., Ltd. Preventive or remedy for intrauterine late embryonic development or pregnancy toxemia
WO2006054514A1 (ja) * 2004-11-19 2006-05-26 Kissei Pharmaceutical Co., Ltd. 神経因性疼痛の予防又は治療用医薬組成物
EP1813285A4 (de) * 2004-11-19 2010-06-09 Kissei Pharmaceutical Prophylaktisches oder therapeutisches mittel gegen neuropathische schmerzen
EP2098511A1 (de) 2008-03-07 2009-09-09 Solvias AG Verfahren zur Herstellung von Verbindungen mit einer Hydronaphtalinstruktur mit einem asymmetrisch substituierten Benzolring
JP2013511528A (ja) * 2009-11-18 2013-04-04 メディシノバ，インコーポレーテッド 喘息の急性憎悪の治療及びそれに罹患した患者の入院の可能性の低減
BR112012022619A2 (pt) * 2010-03-08 2015-10-20 Medicinova Inc composições, métodos, e meios para tratamento da dismenorreia
JP5841994B2 (ja) * 2010-04-08 2016-01-13 メディシノヴァ， インコーポレイテッド． 過敏性腸症候群の処置方法及びその治療用組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9107827D0 (en) * 1991-04-12 1991-05-29 Fujisawa Pharmaceutical Co New ethanolamine derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
IL104567A (en) * 1992-02-03 1997-03-18 Fujisawa Pharmaceutical Co Ethanolamine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
WO1993018007A1 (fr) * 1992-03-13 1993-09-16 Tokyo Tanabe Company Limited Nouveau derive de carbostyrile

Also Published As

Publication number Publication date
KR100491633B1 (ko) 2005-09-09
PL186411B1 (pl) 2004-01-30
SG72727A1 (en) 2000-05-23
NO983777L (no) 1998-10-19
CN1216526A (zh) 1999-05-12
ID16091A (id) 1997-09-04
CZ293974B6 (cs) 2004-09-15
ES2184989T3 (es) 2003-04-16
BR9707566A (pt) 1999-07-27
NO983777D0 (no) 1998-08-18
EP0882704B1 (de) 2002-10-09
CN1100032C (zh) 2003-01-29
AU2001497A (en) 1997-09-02
EP0882704A4 (de) 2000-06-14
KR19990082638A (ko) 1999-11-25
EA002143B1 (ru) 2001-12-24
TW375604B (en) 1999-12-01
JP3892045B2 (ja) 2007-03-14
NZ331445A (en) 2000-01-28
BR9707566B1 (pt) 2010-08-10
HU229400B1 (en) 2013-12-30
WO1997030023A1 (en) 1997-08-21
CZ252398A3 (cs) 1998-12-16
EA199800644A1 (ru) 1999-02-25
MY123853A (en) 2006-06-30
CA2245490A1 (en) 1997-08-21
CA2245490C (en) 2005-10-25
HUP9900621A3 (en) 1999-11-29
AU725042B2 (en) 2000-10-05
DK0882704T3 (da) 2003-02-17
DE69716242T2 (de) 2003-07-24
DE69716242D1 (de) 2002-11-14
EP0882704A1 (de) 1998-12-09
US6133266A (en) 2000-10-17
HUP9900621A2 (hu) 1999-08-30
NO323095B1 (no) 2007-01-02
PT882704E (pt) 2003-02-28
PL328530A1 (en) 1999-02-01

Similar Documents

Publication Publication Date Title
AU623733B2 (en) Benzofused-n-containing heterocyle derivatives
DE69716242D1 (de) 3,4-disubstituierte phenylethanolaminotetralin-carboxamid-derivate
ES2141137T3 (es) Agentes terapeuticos para la enfermedad de parkinson.
DE69713319D1 (de) 3,4-disubstituierte phenylethanolaminotetralincarboxylat-derivate
NO984699D0 (no) Fenyletanolamino-tetralinkarboks-amid-derivater
KR920008034A (ko) 항고혈압 작용 및 혈관 확장 활성있는 벤조피란 유도체, 그의 제법 및 그의 치료적 용도
EP0919233B8 (de) Therapeutisches mittel zur behandlung von nierenerkrankungen
CA2251090A1 (en) Phenylethanolaminotetralincarboxamide derivatives
EP0420464A3 (en) 3-isoxazolone derivatives, their preparation and their therapeutic uses

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0882704

Country of ref document: EP