ATE225847T1 - Verfahren,zusammensetzungen und vorrichtungen zur erhaltung und zur züchtung menschlicher stammzellen und/oder hämatopoetischer zellen - Google Patents

Verfahren,zusammensetzungen und vorrichtungen zur erhaltung und zur züchtung menschlicher stammzellen und/oder hämatopoetischer zellen

Info

Publication number
ATE225847T1
ATE225847T1 AT93908270T AT93908270T ATE225847T1 AT E225847 T1 ATE225847 T1 AT E225847T1 AT 93908270 T AT93908270 T AT 93908270T AT 93908270 T AT93908270 T AT 93908270T AT E225847 T1 ATE225847 T1 AT E225847T1
Authority
AT
Austria
Prior art keywords
cells
compositions
maintaining
methods
devices
Prior art date
Application number
AT93908270T
Other languages
English (en)
Inventor
Bernhard O Palsson
Stephen G Emerson
Richard M Schwartz
Original Assignee
Univ Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Michigan filed Critical Univ Michigan
Application granted granted Critical
Publication of ATE225847T1 publication Critical patent/ATE225847T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/08—Chemical, biochemical or biological means, e.g. plasma jet, co-culture

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT93908270T 1992-03-04 1993-03-04 Verfahren,zusammensetzungen und vorrichtungen zur erhaltung und zur züchtung menschlicher stammzellen und/oder hämatopoetischer zellen ATE225847T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84596992A 1992-03-04 1992-03-04
PCT/US1993/001803 WO1993018132A1 (en) 1992-03-04 1993-03-04 Methods, compositions and devices for maintaining and growing human stem and/or hematopoietic cells

Publications (1)

Publication Number Publication Date
ATE225847T1 true ATE225847T1 (de) 2002-10-15

Family

ID=25296563

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93908270T ATE225847T1 (de) 1992-03-04 1993-03-04 Verfahren,zusammensetzungen und vorrichtungen zur erhaltung und zur züchtung menschlicher stammzellen und/oder hämatopoetischer zellen

Country Status (8)

Country Link
EP (1) EP0629236B1 (de)
JP (1) JPH07504570A (de)
KR (1) KR100271284B1 (de)
AT (1) ATE225847T1 (de)
AU (1) AU685743B2 (de)
CA (1) CA2131385C (de)
DE (1) DE69332374T2 (de)
WO (1) WO1993018132A1 (de)

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US5631219A (en) * 1994-03-08 1997-05-20 Somatogen, Inc. Method of stimulating hematopoiesis with hemoglobin
WO1995024464A1 (en) * 1994-03-11 1995-09-14 Baxter International Inc. Flow-through bioreactor with grooves for cell retention
US5792603A (en) * 1995-04-27 1998-08-11 Advanced Tissue Sciences, Inc. Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native, vascular grafts
US6121042A (en) * 1995-04-27 2000-09-19 Advanced Tissue Sciences, Inc. Apparatus and method for simulating in vivo conditions while seeding and culturing three-dimensional tissue constructs
US5846828A (en) * 1995-06-07 1998-12-08 Advanced Tissue Sciences Apparatus and method for sterilizing, seeding, culturing, storing, shipping, and testing tissue, synthetic, or mechanical heart valves orvalve segments
US5843766A (en) * 1995-06-07 1998-12-01 Advanced Tissue Sciences, Inc. Apparatus for the growth and packaging of three dimensional tissue cultures
US5688687A (en) * 1995-06-07 1997-11-18 Aastrom Biosciences, Inc. Bioreactor for mammalian cell growth and maintenance
AU5931896A (en) * 1995-06-07 1996-12-30 Advanced Tissue Sciences, Inc. Apparatus and method for sterilizing, seeding, culturing, st oring, shipping, and testing replacement cartilage tissue co nstructs
US5763267A (en) * 1996-04-16 1998-06-09 Advanced Tissue Sciences Apparatus for the large scale growth and packaging of cell suspensions and three-dimensional tissue cultures
AU7172598A (en) * 1997-05-07 1998-11-27 Baxter International Inc. Method and apparatus for high volume production of viral particles
FR2771421B1 (fr) * 1997-11-27 2001-05-04 Bertin & Cie Dispositif d'amplification de cellules hematopoietiques et ses applications
NL1017973C2 (nl) * 2000-05-10 2002-11-08 Tristem Trading Cyprus Ltd Inrichting.
AU2002230396B2 (en) * 2000-10-06 2012-06-07 Krstec, Victor System and method to simulate hemodynamics
DE10128810B4 (de) * 2001-06-18 2013-11-07 Pan-Biotech Gmbh Einrichtung zur Kultivierung von Zellen, insbesondere menschlicher oder tierischer Zellen
US8492140B2 (en) * 2002-04-08 2013-07-23 Octane Biotech Inc. Automated tissue engineering system
DE10223536A1 (de) * 2002-05-27 2003-12-18 J Hinrich Peters Verfahren zur Trennung nicht-adhärenter Zellen von adhärenten Zellen
DE50211123D1 (de) 2002-09-16 2007-12-06 Pan Biotech Gmbh Verfahren zur kultivierung von zellen, insbesondere menschlicher oder tierischer zellen
CN1993460A (zh) * 2004-07-12 2007-07-04 索林集团意大利有限公司 用于培养人细胞的装置和方法
US8846393B2 (en) 2005-11-29 2014-09-30 Gamida-Cell Ltd. Methods of improving stem cell homing and engraftment
WO2008028241A1 (en) * 2006-09-06 2008-03-13 The University Of Queensland Microbioreactor
JP5666131B2 (ja) * 2008-02-22 2015-02-12 コバレントマテリアル株式会社 細胞培養モジュール
EP2449095A1 (de) * 2009-07-02 2012-05-09 Anthrogenesis Corporation Verfahren zur produktion von erythrozyten ohne feederzellen
GB0914195D0 (en) * 2009-08-13 2009-09-16 Plasticell Ltd Vessel for culturing cells
AU2012271341B2 (en) 2011-06-15 2017-07-13 The Charles Stark Draper Laboratory, Inc. Systems, methods, and devices relating to a biomimetic cellularized nephron unit
JP2014516582A (ja) * 2011-06-15 2014-07-17 ザ チャールズ スターク ドレイパー ラボラトリー インク 生体模倣環境において細胞を培養するためのデバイスおよび方法
WO2013121426A1 (en) 2012-02-13 2013-08-22 Gamida-Cell Ltd. Culturing of mesenchymal stem cells
US9175266B2 (en) 2012-07-23 2015-11-03 Gamida Cell Ltd. Enhancement of natural killer (NK) cell proliferation and activity
US9567569B2 (en) 2012-07-23 2017-02-14 Gamida Cell Ltd. Methods of culturing and expanding mesenchymal stem cells
JP5828823B2 (ja) * 2012-09-28 2015-12-09 クアーズテック株式会社 細胞培養モジュール及び細胞培養方法
JP6311609B2 (ja) * 2012-10-17 2018-04-18 コニカミノルタ株式会社 希少細胞の回収方法および検出方法
JP2014124097A (ja) * 2012-12-25 2014-07-07 Hitachi High-Technologies Corp 核酸分析用カートリッジ及び核酸分析装置
US20170158999A1 (en) * 2015-12-03 2017-06-08 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Modular bioreactor for culture of biopaper based tissues
CA3034452A1 (en) 2016-08-21 2018-03-01 Adva Biotechnology Ltd. Bioreactor and methods of use thereof
KR102546681B1 (ko) * 2017-09-01 2023-06-22 론차 콜로그네 게엠베하 엔드-투-엔드 세포 요법의 자동화
DE202018000370U1 (de) 2018-01-24 2018-04-12 Zellwerk Gmbh Mäander-Bioreaktor für die Isolierung und Vermehrung von Zellen aus Gewebeteilen von Tumoren, Metastasen und anderen Geweben
DE102018000561B4 (de) 2018-01-24 2019-11-07 Zellwerk Gmbh Mäander-Bioreaktor und Verfahren für die Isolierung und Vermehrung von Zellen aus Gewebeteilen von Tumoren, Metastasen und anderen Geweben
DE202018004857U1 (de) 2018-10-20 2019-01-14 Zellwerk Gmbh Mäander-Perfusions-Bioreaktor für die Differenzierung, Aktivierung, Stimulierung und Abtrennung von Zellen
US20230242864A1 (en) * 2022-01-31 2023-08-03 Sciperio, Inc In-time storage of manufactured cells for medical cellular therapy grown and differentiated in bioreactors
EP4596667A1 (de) 2024-01-30 2025-08-06 Green Elephant Biotech GmbH Bioreaktor und prozessleitsystem

Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
DE2726313C3 (de) * 1977-06-10 1980-02-07 Battelle-Institut E.V., 6000 Frankfurt Verfahren zur in-vitro-Biosynthese von Hormonen, insbesondere von Insulin
AU2232683A (en) * 1982-12-15 1984-06-21 Bio-Response Inc. Method and apparatus for cell propagation
US5135853A (en) * 1983-07-22 1992-08-04 Rensselaer Polytechnic Institute Three compartment bioreactor and method of use
DE3409501A1 (de) * 1984-03-15 1985-10-24 Sandoz-Patent-GmbH, 7850 Lörrach Verfahren zur kultivierung von zellen
US4894342A (en) * 1986-05-12 1990-01-16 C. D. Medical, Inc. Bioreactor system
US4861483A (en) * 1986-07-07 1989-08-29 Cornell Research Foundation, Inc. Apparatus and process to eliminate diffusional limitations in a membrane biological reactor by pressure cycling
US5399493A (en) * 1989-06-15 1995-03-21 The Regents Of The University Of Michigan Methods and compositions for the optimization of human hematopoietic progenitor cell cultures
KR100196062B1 (ko) * 1989-06-15 1999-06-15 로버트 에프. 게이민 세포를 성장시키기 위한 방법, 조성물 및 장치
ATE143999T1 (de) * 1991-06-19 1996-10-15 Endotronics Inc Zellkultur apparat
DE4206585C2 (de) * 1992-03-03 1994-11-24 Augustinus Dr Med Bader Vorrichtung zur Massenkultur von Zellen

Also Published As

Publication number Publication date
JPH07504570A (ja) 1995-05-25
DE69332374T2 (de) 2003-06-12
EP0629236B1 (de) 2002-10-09
AU685743B2 (en) 1998-01-29
DE69332374D1 (de) 2002-11-14
CA2131385A1 (en) 1993-09-16
AU3914893A (en) 1993-10-05
EP0629236A1 (de) 1994-12-21
CA2131385C (en) 2008-07-15
WO1993018132A1 (en) 1993-09-16
EP0629236A4 (de) 1997-06-04
KR100271284B1 (ko) 2000-11-01

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