ATE226727T1 - Leistungssteigerung von bindungsassays mit verwendung mehr als einer markierungsmittel - Google Patents

Leistungssteigerung von bindungsassays mit verwendung mehr als einer markierungsmittel

Info

Publication number
ATE226727T1
ATE226727T1 AT98900644T AT98900644T ATE226727T1 AT E226727 T1 ATE226727 T1 AT E226727T1 AT 98900644 T AT98900644 T AT 98900644T AT 98900644 T AT98900644 T AT 98900644T AT E226727 T1 ATE226727 T1 AT E226727T1
Authority
AT
Austria
Prior art keywords
binding assay
improving
performance
marking agent
analyte
Prior art date
Application number
AT98900644T
Other languages
English (en)
Inventor
Uri Piran
John J Quinn
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of ATE226727T1 publication Critical patent/ATE226727T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT98900644T 1997-01-31 1998-02-02 Leistungssteigerung von bindungsassays mit verwendung mehr als einer markierungsmittel ATE226727T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/791,591 US6087088A (en) 1997-01-31 1997-01-31 Binding assays using more than one label for determining analyte in the presence of interfering factors
PCT/IB1998/000125 WO1998034109A1 (en) 1997-01-31 1998-02-02 Improving performance of binding assays by use of more than one label

Publications (1)

Publication Number Publication Date
ATE226727T1 true ATE226727T1 (de) 2002-11-15

Family

ID=25154194

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98900644T ATE226727T1 (de) 1997-01-31 1998-02-02 Leistungssteigerung von bindungsassays mit verwendung mehr als einer markierungsmittel

Country Status (8)

Country Link
US (1) US6087088A (de)
EP (1) EP0968422B1 (de)
JP (1) JP2001511890A (de)
AT (1) ATE226727T1 (de)
AU (1) AU5572998A (de)
DE (1) DE69808895T2 (de)
ES (1) ES2186121T3 (de)
WO (1) WO1998034109A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010026920A1 (en) * 2000-02-25 2001-10-04 Mark Chandler Internal standards and controls for multiplexed assay
JP2004510161A (ja) * 2000-09-25 2004-04-02 アボット・ラボラトリーズ 高分子ポリカチオンを用いることにより、特異的結合アッセイにおける血清または血漿含有アッセイ試料の干渉を減少させるための方法及びキット
US6780602B2 (en) * 2001-11-01 2004-08-24 Microbiosystems, Limited Partnership Taxonomic identification of pathogenic microorganisms and their toxic proteins
GB0310270D0 (en) * 2003-05-03 2003-06-11 Univ Edinburgh Biomolecular devices
US7723099B2 (en) * 2003-09-10 2010-05-25 Abbott Point Of Care Inc. Immunoassay device with immuno-reference electrode
US20060257929A1 (en) * 2003-11-12 2006-11-16 Microbiosystems, Limited Partnership Method for the rapid taxonomic identification of pathogenic microorganisms and their toxic proteins
JP2008516641A (ja) * 2004-08-23 2008-05-22 リモート クリニカル ソリューションズ インコーポレイテッド 経口投与するための流体を変更するためのシステム及び方法
US8470608B2 (en) * 2008-05-20 2013-06-25 Rapid Pathogen Screening, Inc Combined visual/fluorescence analyte detection test
US8445293B2 (en) 2005-02-09 2013-05-21 Rapid Pathogen Screening, Inc. Method to increase specificity and/or accuracy of lateral flow immunoassays
JP2009524834A (ja) * 2006-01-27 2009-07-02 オクソニカ・インコーポレーテッド 被包検出様式を用いた側方流動イムノアッセイ
US8084223B2 (en) * 2009-03-23 2011-12-27 Siemens Healthcare Diagnostics Inc. Detection of false results in assays
CN101864288B (zh) * 2009-04-14 2013-11-13 博阳生物科技（上海）有限公司 游离三碘甲腺原氨酸检测微粒、其制备及应用
US9880156B2 (en) 2013-04-11 2018-01-30 Medite Cancer Diagnostics, Inc. Biological specimen evaluation methods using cytology and immunology
EP3176580A1 (de) 2015-12-01 2017-06-07 Roche Diagnostics GmbH Verfahren zur reduzierung von interferenzen in immunoassays

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713347A (en) * 1985-01-14 1987-12-15 Sensor Diagnostics, Inc. Measurement of ligand/anti-ligand interactions using bulk conductance
JP2802921B2 (ja) * 1986-06-17 1998-09-24 マイクロスキャン、インコーポレイテッド 蛍光バックグラウンド消去および水溶性希土類金属キレートフルオロフォルを使用する均質蛍光アッセイ
US5409814A (en) * 1987-04-10 1995-04-25 Boehringer Mannheim Gmbh Determination of ions in fluids
GB8800419D0 (en) * 1988-01-08 1988-02-10 Amersham Int Plc Method for measuring free fraction of ligands in biological fluids
DE3900534A1 (de) * 1989-01-10 1990-07-12 Boehringer Mannheim Gmbh Diagnostischer nachweis unter verwendung von chimaeren antikoerpern
JP2683172B2 (ja) * 1991-10-01 1997-11-26 キヤノン株式会社 検体測定方法及び検体測定装置
US5366859A (en) * 1991-10-31 1994-11-22 Mitsubishi Petrochemical Co., Ltd. Radioimmunoassay method
DE69328727T2 (de) * 1992-08-03 2000-09-07 Gec-Marconi Ltd., Stanmore Immunologisches nachweisverfahren unter verwendung von zwei bestimmbaren markern
DE19504198A1 (de) * 1995-02-09 1996-08-14 Behringwerke Ag Kompetitiver Immuntest unter Verwendung komplexierter Analytderivate
US5783453A (en) * 1995-06-29 1998-07-21 Chiron Diagnostics Corporation Non-separation specific binding chemiluminescent assay
EP0852012B1 (de) * 1996-05-01 2006-07-26 Dade Behring Marburg GmbH Chemilumineszente zusammensetungen und ihre verwendung zum nachweis von wasserstoffperoxid

Also Published As

Publication number Publication date
WO1998034109A1 (en) 1998-08-06
US6087088A (en) 2000-07-11
DE69808895D1 (de) 2002-11-28
AU5572998A (en) 1998-08-25
ES2186121T3 (es) 2003-05-01
EP0968422B1 (de) 2002-10-23
JP2001511890A (ja) 2001-08-14
DE69808895T2 (de) 2003-02-27
EP0968422A1 (de) 2000-01-05

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